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In concordance, NahG potato plants were more sensitive to treatment with methyl viologen, a reactive oxygen species\u2013generating compound. In addition, when challenged with PVX ROTH1, NahG transgenic lines showed a decreased disease-resistance response to infection and were unable to induce systemic acquired resistance. However, the avirulent viral effector, the PVX 25-kDa protein, does induce expression of the pathogenesis-related gene PR-1a in NahG potato plants. Taken together, our data indicate that SA is involved in local and systemic defense responses mediated by the Nb gene in Solanum tuberosum. This is the first report to show that basal levels of SA correlate with hypersensitive resistance to PVX. <\/jats:p>","DOI":"10.1094\/mpmi-23-4-0394","type":"journal-article","created":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T21:14:44Z","timestamp":1267478084000},"page":"394-405","source":"Crossref","is-referenced-by-count":45,"title":["Salicylic Acid Is Involved in the <i>Nb<\/i>-Mediated Defense Responses to <i>Potato virus X<\/i> in <i>Solanum tuberosum<\/i>"],"prefix":"10.1094","volume":"23","author":[{"given":"Gerardo","family":"S\u00e1nchez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadia","family":"Gerhardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Florencia","family":"Siciliano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adri\u00e1n","family":"Vojnov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Malcuit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Rosa","family":"Marano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1665","reference":[{"key":"p_1","doi-asserted-by":"crossref","unstructured":"Asada, K. 1996. 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