{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,30]],"date-time":"2025-03-30T04:02:21Z","timestamp":1743307341539,"version":"3.40.3"},"reference-count":14,"publisher":"Scientific Societies","issue":"3","funder":[{"DOI":"10.13039\/100005825","name":"U.S. Department of Agriculture \u2013 National Institute of Food and Agriculture","doi-asserted-by":"crossref","award":["SC-1700594"],"award-info":[{"award-number":["SC-1700594"]}],"id":[{"id":"10.13039\/100005825","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Plant Disease"],"published-print":{"date-parts":[[2025,3,1]]},"abstract":"<jats:p> Fludioxonil and propiconazole are frequently used fungicides for managing fungal diseases in specialty crops. They are often used in mixture to manage postharvest brown rot caused by Monilinia fructicola and sour rot caused by the yeast-like fungus Geotrichum candidum on stone fruits. Previous research indicated, however, that fludioxonil can increase the expression of the ATP-binding cassette transporters CDR1 and CDR2 in the yeast Candida albicans, leading to increased resistance to demethylation inhibitor (DMI) fungicides. In this study, mycelial growth assays and detached fruit assays were conducted with G. candidum isolates of varying sensitivity to propiconazole to investigate potential antagonism between the two active ingredients. Isolates sensitive, reduced-sensitive, and resistant to propiconazole were able to grow with or without 20 \u03bcg\/ml of fludioxonil on potato dextrose agar containing up to 0, 3, and 30 \u03bcg\/ml of propiconazole and on water agar containing up to 7.5, 7.5, and 30 \u03bcg\/ml of propiconazole, respectively, and no antagonistic interactions were detected. Propiconazole controlled disease with or without 20 \u03bcg\/ml of fludioxonil equally on detached cherry fruit caused by isolates with different DMI sensitivity phenotypes. Our results indicated no detectable antagonism between fludioxonil and propiconazole that would interfere with the mixture\u2019s ability to manage sour rot of cherry. <\/jats:p>","DOI":"10.1094\/pdis-08-24-1675-sc","type":"journal-article","created":{"date-parts":[[2024,10,23]],"date-time":"2024-10-23T15:16:43Z","timestamp":1729696603000},"page":"558-561","source":"Crossref","is-referenced-by-count":0,"title":["Fludioxonil Does Not Antagonize Propiconazole Activity Against <i>Geotrichum candidum<\/i>"],"prefix":"10.1094","volume":"109","author":[{"given":"Bingyu","family":"Zhao","sequence":"first","affiliation":[{"name":"Department of Plant and Environmental Sciences, Clemson University, Clemson, SC 29634, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhezheng","family":"Zeng","sequence":"additional","affiliation":[{"name":"National Key Laboratory for Germplasm Innovation and Utilization of Horticultural Crops, and College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jhulia","family":"Gelain","sequence":"additional","affiliation":[{"name":"Department of Plant and Environmental Sciences, Clemson University, Clemson, SC 29634, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9385-9898","authenticated-orcid":false,"given":"Chao-Xi","family":"Luo","sequence":"additional","affiliation":[{"name":"National Key Laboratory for Germplasm Innovation and Utilization of Horticultural Crops, and College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9642-1920","authenticated-orcid":false,"given":"Guido","family":"Schnabel","sequence":"additional","affiliation":[{"name":"Department of Plant and Environmental Sciences, Clemson University, Clemson, SC 29634, U.S.A."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1665","reference":[{"key":"b1","doi-asserted-by":"publisher","DOI":"10.1016\/S0141-0229(02)00149-7"},{"volume-title":"2024 Southeastern Peach, Nectarine, and Plum Pest Management and Culture Guide","year":"2024","author":"Blaauw B.","key":"b2"},{"key":"b3","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.050963-0"},{"key":"b4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijfoodmicro.2014.11.009"},{"key":"b5","doi-asserted-by":"publisher","DOI":"10.1006\/fgbi.2000.1206"},{"key":"b6","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9063(199711)51:3<271::AID-PS642>3.0.CO;2-#"},{"key":"b7","doi-asserted-by":"publisher","DOI":"10.1002\/ps.1150"},{"key":"b8","doi-asserted-by":"publisher","DOI":"10.1094\/PHYTO.1997.87.5.500"},{"key":"b9","first-page":"S1.86","volume":"114","author":"Gelain J.","year":"2024","journal-title":"Phytopathology"},{"key":"b10","doi-asserted-by":"publisher","DOI":"10.3390\/jof9090917"},{"key":"b11","doi-asserted-by":"publisher","DOI":"10.1007\/BF00352101"},{"key":"b12","unstructured":"Price, S. 2023. Identification and Characterization of Geotrichum candidum Isolates from Peach with Reduced Sensitivity to Propiconazole. M.S. thesis. Clemson University, Clemson, SC. https:\/\/tigerprints.clemson.edu\/all_theses\/4183"},{"key":"b13","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.11.2378"},{"key":"b14","doi-asserted-by":"publisher","DOI":"10.1094\/PDIS-09-11-0796"}],"container-title":["Plant Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/apsjournals.apsnet.org\/doi\/pdf\/10.1094\/PDIS-08-24-1675-SC","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,29]],"date-time":"2025-03-29T04:21:01Z","timestamp":1743222061000},"score":1,"resource":{"primary":{"URL":"https:\/\/apsjournals.apsnet.org\/doi\/10.1094\/PDIS-08-24-1675-SC"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,1]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3,1]]}},"alternative-id":["10.1094\/PDIS-08-24-1675-SC"],"URL":"https:\/\/doi.org\/10.1094\/pdis-08-24-1675-sc","relation":{},"ISSN":["0191-2917","1943-7692"],"issn-type":[{"type":"print","value":"0191-2917"},{"type":"electronic","value":"1943-7692"}],"subject":[],"published":{"date-parts":[[2025,3,1]]}}}