{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,20]],"date-time":"2026-06-20T14:53:49Z","timestamp":1781967229778,"version":"3.54.5"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,3,1]]},"DOI":"10.1095\/biolreprod.102.009738","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T18:30:50Z","timestamp":1098297050000},"page":"888-895","source":"Crossref","is-referenced-by-count":22,"title":["Epididymal Phenotype in Luteinizing Hormone Receptor Knockout Animals and Its Response to Testosterone Replacement Therapy1"],"prefix":"10.1093","volume":"68","author":[{"given":"Z.M.","family":"Lei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"X.","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ch. V.","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224175936_R1","first-page":"999","article-title":"Efferent ducts, epididymis, and vas deferens: structure, functions, and their regulation","year":"1988"},{"key":"key\n\t\t\t\t20170224175936_R2","first-page":"691","article-title":"Anatomy of mammalian male accessory reproductive organs","volume-title":"Marshall's Physiology of Reproduction","year":"1990"},{"key":"key\n\t\t\t\t20170224175936_R3","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S0074-7696(08)61567-3","article-title":"Gene expression in the epididymis","volume":"188","year":"1999","journal-title":"Int Rev Cytol"},{"key":"key\n\t\t\t\t20170224175936_R4","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1095\/biolreprod65.3.696","article-title":"Dynamic changes in gene expression along the rat epididymis","volume":"65","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175936_R5","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1038\/216816a0","article-title":"Sperm maturation in rabbit epididymis","volume":"216","year":"1967","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224175936_R6","first-page":"53","article-title":"Sperm dynamics in the epididymis","volume-title":"Gamete Physiology","year":"1992"},{"key":"key\n\t\t\t\t20170224175936_R7","first-page":"27","article-title":"Androgens and epididymal function","volume-title":"Pharmacology, Biology and Clinical Applications of Androgens","year":"1996"},{"key":"key\n\t\t\t\t20170224175936_R8","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1038\/258145a0","article-title":"Alteration of epididymal sperm transport and maturation in mice by oestrogen and testosterone","volume":"258","year":"1975","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224175936_R9","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1095\/biolreprod21.1.135","article-title":"Properties of a prolactin receptor from the rabbit epididymis","volume":"21","year":"1979","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175936_R10","first-page":"91","article-title":"1, 25-dihydroxyvitamin D3 receptors: exchange assay and presence in reproductive tissues","year":"1982"},{"key":"key\n\t\t\t\t20170224175936_R11","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1095\/biolreprod27.4.771","article-title":"Effects of spironolactone (aldosterone antagonist) on electrolytes and water content of the cauda epididymidis and fertility of male rats","volume":"27","year":"1982","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175936_R12","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1210\/endo-113-5-1703","article-title":"The effects of estradiol, tamoxifen, and testosterone on the weights and histology of the epididymis and accessory sex organs of sexually immature rabbits","volume":"113","year":"1983","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224175936_R13","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1002\/j.1939-4640.1985.tb00836.x","article-title":"Localization of cellular retinol-binding protein and cellular retinoic acid-binding protein in the rat testis and epididymis","volume":"6","year":"1985","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224175936_R14","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1111\/j.1476-5381.1989.tb12664.x","article-title":"Endothelin stimulates short circuit current in cultured rat epididymal epithelium","volume":"98","year":"1989","journal-title":"Brit J Pharmacol"},{"key":"key\n\t\t\t\t20170224175936_R15","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1677\/joe.0.1250449","article-title":"Effect of angiotensins on electrogenic anion transport in monolayer cultures of rat epididymis","volume":"125","year":"1990","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R16","first-page":"(abstract PS255)","article-title":"Effect of hCG on intracellular chloride concentration in rat epididymal cells","volume":"14","year":"1993","journal-title":"Clin Biochem Rev"},{"key":"key\n\t\t\t\t20170224175936_R17","doi-asserted-by":"crossref","first-page":"C607","DOI":"10.1152\/ajpcell.1994.267.2.C607","article-title":"The effect of [Arg8]-vasopressin on electrogenic chloride secretion in cultured rat epididymal epithelia","volume":"267","year":"1994","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20170224175936_R18","first-page":"abstract 338 (141)","article-title":"Novel expression of luteinizing hormone (LH)\/human chorionic gonadotropin (hCG) receptor gene in rat epididymis","volume":"52","year":"1995","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175936_R19","first-page":"1608","article-title":"Rat epididymis expresses luteinizing hormone receptor (LHR)","volume":"41","year":"1996","journal-title":"Chinese Sci Bull"},{"key":"key\n\t\t\t\t20170224175936_R20","article-title":"Human epididymis contains luteinizing hormone\/chorionic gonadotropin receptors","year":"1996"},{"key":"key\n\t\t\t\t20170224175936_R21","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/molehr\/3.11.945","article-title":"Localization of plasminogen activator and inhibitor, LH and androgen receptors and inhibin subunits in monkey epididymis","volume":"3","year":"1997","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224175936_R22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0167-4889(97)00015-3","article-title":"Angiotensin II receptors, AT1 and AT2, in the rat epididymis: immunocytochemical and electrophysiological studies","volume":"1357","year":"1997","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170224175936_R23","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1677\/joe.0.1540389","article-title":"Local regulation of epididymal anion secretion by pituitary adenylate cyclase-activating polypeptide","volume":"154","year":"1997","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R24","first-page":"15","article-title":"The role of local angiotensins and prostaglandins in the control of anion secretion by the rat epididymis","volume":"53","year":"1998","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224175936_R25","first-page":"466","article-title":"Glycoprotein hormones: structure and function","volume":"50","year":"1981","journal-title":"Annu Rev Biochem"},{"key":"key\n\t\t\t\t20170224175936_R26","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/369455a0","article-title":"Crystal structure of human chorionic gonadotropin","volume":"369","year":"1994","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224175936_R27","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1530\/acta.0.0900696","article-title":"Differential properties of human chorionic gonadotropin and human luteinizing hormone binding to plasma membranes of bovine corpora lutea","volume":"90","year":"1979","journal-title":"Acta Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R28","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1210\/mend-5-6-759","article-title":"Expression of human luteinizing hormone (LH) receptor: interaction with LH and chorionic gonadotropin from human but not equine, rat and ovine species","volume":"5","year":"1991","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R29","doi-asserted-by":"crossref","first-page":"R9","DOI":"10.1016\/0303-7207(95)03564-N","article-title":"Novel expression of luteinizing hormone\/chorionic gonadotropin receptor gene in rat prostate","volume":"111","year":"1995","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R30","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1210\/endo.136.3.7867600","article-title":"Expression and functionality of luteinizing hormone\/chorionic gonadotropin receptor in the rat prostate","volume":"136","year":"1995","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224175936_R31","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1095\/biolreprod56.1.67","article-title":"Expression of luteinizing hormone\/human chorionic gonadotropin receptor gene in benign prostatic hyperplasia and in prostate carcinoma in humans","volume":"56","year":"1997","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175936_R32","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1006\/bbrc.1997.6412","article-title":"Luteinizing hormone increases the abundance of various transcripts, independently of the androgens in the rat prostate","volume":"233","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170224175936_R33","article-title":"The presence of functional luteinizing hormone\/chorionic gonadotropin receptors in human prostate cell lines","year":"1997"},{"key":"key\n\t\t\t\t20170224175936_R34","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/j.1939-4640.1998.tb02014.x","article-title":"Seminal vesicles are novel sites of luteinizing hormone\/human chorionic gonadotropin receptor gene expression","volume":"19","year":"1998","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224175936_R35","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1002\/(SICI)1097-0045(19980515)35:3<212::AID-PROS7>3.0.CO;2-I","article-title":"Coexpression of gonadotropic hormones and their corresponding FSH and LH\/CG-receptors in the human prostate","volume":"35","year":"1998","journal-title":"Prostate"},{"key":"key\n\t\t\t\t20170224175936_R36","first-page":"3","article-title":"Direct luteinizing hormone regulation of the male reproductive tract","volume-title":"Current Knowledge in Reproductive Medicine","year":"2000"},{"key":"key\n\t\t\t\t20170224175936_R37","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1210\/mend.15.1.0586","article-title":"Targeted disruption of luteinizing hormone\/human chorionic gonadotropin receptor gene","volume":"15","year":"2001","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R38","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1210\/mend.15.1.0582","article-title":"Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice","volume":"15","year":"2001","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R39","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0303-7207(95)03497-U","article-title":"Signaling and transacting factors in the transcriptional inhibition of gonadotropin releasing hormone gene by human chorionic gonadotropin in immortalized hypothalamic GT1\u20137 neurons","volume":"109","year":"1995","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R40","first-page":"1111","article-title":"Novel presence of luteinizing hormone\/human chorionic gonadotropin (hCG) receptors and the down-regulating action of hCG on gonadotropin releasing hormone gene expression in immortalized hypothalamic GT1\u20137 neurons","volume":"8","year":"1994","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R41","article-title":"Principles and Procedures of Statistics, with Special Reference to the Biological Sciences","year":"1960"},{"key":"key\n\t\t\t\t20170224175936_R42","first-page":"abstract 236 (200)","article-title":"Gonadal failure in LH\/hCG receptor knockout mice: increased apoptosis and decreased telomerase levels","volume":"62","year":"2000","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175936_R43","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1530\/eje.0.1330235","article-title":"Endocrine control of testicular somatic and premeiotic germ cell development in the immature testis of the primate Macaca mulatta","volume":"133","year":"1995","journal-title":"Eur J Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R44","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0303-7207(01)00694-3","article-title":"Consequences of targeted inactivation of LH receptors","volume":"187","year":"2002","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224175936_R45","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/37352","article-title":"A role for oestrogens in the male reproductive system","volume":"390","year":"1997","journal-title":"Nature"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/68\/3\/888\/10558782\/biolreprod0888.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T02:31:34Z","timestamp":1734575494000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.102.009738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,3,1]]},"references-count":45,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,3,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.102.009738","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,3,1]]}}}