{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:01:45Z","timestamp":1791216105097,"version":"4.1.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,7,1]]},"DOI":"10.1095\/biolreprod.102.010975","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T18:30:50Z","timestamp":1098297050000},"page":"254-260","source":"Crossref","is-referenced-by-count":149,"title":["Ubiquitination of Prohibitin in Mammalian Sperm Mitochondria: Possible Roles in the Regulation of Mitochondrial Inheritance and Sperm Quality Control1"],"prefix":"10.1093","volume":"69","author":[{"given":"Winston E.","family":"Thompson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Ramalho-Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Sutovsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224175159_R1","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1038\/46466","article-title":"Ubiquitin tag for sperm mitochondria","volume":"402","year":"1999","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224175159_R2","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1095\/biolreprod63.2.582","article-title":"Ubiquitinated sperm mitochondria, selective proteolysis and the regulation of mitochondrial inheritance in mammalian embryos","volume":"63","year":"2000","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175159_R3","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1038\/35047064","article-title":"Mitochondrial genome variation and the origin of modern humans","volume":"408","year":"2000","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224175159_R4","doi-asserted-by":"crossref","first-page":"4542","DOI":"10.1073\/pnas.92.10.4542","article-title":"Elimination of paternal mitochondrial DNA in intraspecific crosses during early mouse embryogenesis","volume":"92","year":"1995","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224175159_R5","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1093\/genetics\/156.3.1277","article-title":"Selective and continuous elimination of mitochondria microinjected into mouse eggs from spermatids, but not from liver cells, occurs throughout embryogenesis","volume":"156","year":"2000","journal-title":"Genetics"},{"key":"key\n\t\t\t\t20170224175159_R6","first-page":"576","article-title":"Paternal inheritance of mitochondrial DNA","volume":"22","year":"2002","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170224175159_R7","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.biochem.67.1.425","article-title":"The ubiquitin system","volume":"67","year":"1998","journal-title":"Annu Rev Biochem"},{"key":"key\n\t\t\t\t20170224175159_R8","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1126\/science.1067466","article-title":"Emerging roles of ubiquitin in transcription regulation","volume":"296","year":"2002","journal-title":"Science"},{"key":"key\n\t\t\t\t20170224175159_R9","doi-asserted-by":"crossref","first-page":"13165","DOI":"10.1074\/jbc.273.21.13165","article-title":"Ubiquitination of histone H3 in elongating spermatids of rat testes","volume":"273","year":"1998","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224175159_R10","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1006\/dbio.1998.9155","article-title":"Histone ubiquitination and chromatin remodeling in mouse spermatogenesis","volume":"207","year":"1999","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224175159_R11","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/dbio.1999.9342","article-title":"Activation of a UBC4-dependent pathway of ubiquitin conjugation during postnatal development of the rat testis","volume":"212","year":"1999","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224175159_R12","doi-asserted-by":"crossref","first-page":"4064","DOI":"10.1128\/MCB.16.8.4064","article-title":"A novel rat homolog of the Saccharomyces cerevisiae ubiquitin-conjugating enzymes UBC4 and UBC5 with distinct biochemical features is induced during spermatogenesis","volume":"16","year":"1996","journal-title":"Mol Cell Biol"},{"key":"key\n\t\t\t\t20170224175159_R13","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1095\/biolreprod55.2.291","article-title":"Light and electron microscopic immunohistochemical localization of protein gene product 9.5 and ubiquitin immunoreactivities in the human epididymis and vas deferens","volume":"55","year":"1996","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175159_R14","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1242\/jcs.114.9.1665","article-title":"A putative, ubiquitin-dependent mechanism for the recognition and elimination of defective spermatozoa in the mammalian epididymis","volume":"114","year":"2001","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170224175159_R15","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1002\/j.1939-4640.1993.tb01666.x","article-title":"Immunoreactive ubiquitin in human seminal plasma","volume":"14","year":"1993","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224175159_R16","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1093\/humrep\/16.2.250","article-title":"Ubiquitin-based sperm assay for the diagnosis of male factor infertility","volume":"16","year":"2001","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170224175159_R17","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1093\/humrep\/17.8.2119","article-title":"Sperm Ubiquitination in Patients with Dysplasia of the Fibrous Sheath","volume":"17","year":"2002","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170224175159_R18","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0167-4889(02)00267-7","article-title":"Membrane protein degradation by AAA proteases in mitochondria","volume":"1592","year":"2002","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170224175159_R19","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1095\/biolreprod49.2.300","article-title":"Expression of prohibitin in rat seminiferous epithelium","volume":"49","year":"1993","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175159_R20","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1016\/0006-291X(89)91813-5","article-title":"Isolation of a cDNA that hybrid selects antiproliferative mRNA from rat liver","volume":"164","year":"1989","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170224175159_R21","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1128\/MCB.11.3.1372","article-title":"Prohibitin, an evolutionarily conserved intracellular protein that blocks DNA synthesis in normal fibroblasts and HeLa cells","volume":"11","year":"1991","journal-title":"Mol Cell Biol"},{"key":"key\n\t\t\t\t20170224175159_R22","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0531-5565(94)00069-7","article-title":"Prohibitin: potential role in senescence, development, and tumor suppression","volume":"30","year":"1995","journal-title":"Exp Gerontol"},{"key":"key\n\t\t\t\t20170224175159_R23","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/jcp.1041570211","article-title":"Cell cycle activity and expression of prohibitin mRNA","volume":"157","year":"1993","journal-title":"J Cell Physiol"},{"key":"key\n\t\t\t\t20170224175159_R24","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1530\/jrf.0.1090337","article-title":"Steroidogenic acute regulatory (StAR) protein (p25) and prohibitin (p28) from cultured rat ovarian granulosa cells","volume":"109","year":"1997","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224175159_R25","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/(SICI)1097-0185(19990901)256:1<40::AID-AR6>3.0.CO;2-X","article-title":"Immunolocalization and expression of prohibitin, a mitochondrial associated protein within the rat ovaries","volume":"256","year":"1999","journal-title":"Anat Rec"},{"key":"key\n\t\t\t\t20170224175159_R26","doi-asserted-by":"crossref","first-page":"4076","DOI":"10.1210\/endo.142.9.8354","article-title":"Characterization of prohibitin in a newly established rat ovarian granulosa cell line","volume":"142","year":"2001","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224175159_R27","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1006\/excr.1995.1194","article-title":"Prohibitin antiproliferative activity and lack of heterozygosity in immortalized cell lines","volume":"218","year":"1995","journal-title":"Exp Cell Res"},{"key":"key\n\t\t\t\t20170224175159_R28","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1006\/excr.1996.0120","article-title":"The 3\u2032 untranslated region of prohibitin and cellular immortalization","volume":"224","year":"1996","journal-title":"Exp Cell Res"},{"key":"key\n\t\t\t\t20170224175159_R29","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1002\/mrd.10101","article-title":"Ubiquitin-dependent, sperm quality control mechanism recognizes spermatozoa with DNA defects, as revealed by dual ubiquitin-TUNEL assay","volume":"61","year":"2002","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224175159_R30","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/978-1-4899-1922-9_2","article-title":"Polyubiquitin chains","volume-title":"Ubiquitin and the Biology of the Cell","year":"1998"},{"key":"key\n\t\t\t\t20170224175159_R31","first-page":"1793","article-title":"Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG 132","volume":"68","year":"2002","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175159_R32","doi-asserted-by":"crossref","first-page":"31567","DOI":"10.1074\/jbc.M101760200","article-title":"Characterization of Sptrx, a novel member of the thioredoxin family specifically expressed in human spermatozoa","volume":"276","year":"2001","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224175159_R33","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0012-1606(84)90126-X","article-title":"The role of disulfide bond reduction during mammalian sperm nuclear decondensation in vivo","volume":"101","year":"1984","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224175159_R34","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1095\/biolreprod56.6.1503","article-title":"Depletion of glutathione during oocyte maturation reversibly blocks the decondensation of the male pronucleus and pronuclear apposition during fertilization","volume":"56","year":"1997","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224175159_R35","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/(SICI)1098-2795(199811)51:3<243::AID-MRD3>3.0.CO;2-P","article-title":"Expression and regulation of genes associated with cell death during murine preimplantation embryo development","volume":"51","year":"1998","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224175159_R36","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1038\/nrm731","article-title":"Deadly encounter: ubiquitin meets apoptosis","volume":"3","year":"2002","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key\n\t\t\t\t20170224175159_R37","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1083\/jcb.145.6.1199","article-title":"A role for ubiquitination in mitochondrial inheritance in Saccharomyces cerevisiae","volume":"145","year":"1999","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170224175159_R38","doi-asserted-by":"crossref","first-page":"4043","DOI":"10.1128\/MCB.18.7.4043","article-title":"Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae","volume":"18","year":"1998","journal-title":"Mol Cell Biol"},{"key":"key\n\t\t\t\t20170224175159_R39","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/jemt.10319","article-title":"Ubiquitin-dependent proteolysis in mammalian spermatogenesis, fertilization, and sperm quality control: killing three birds with one stone","volume":"61","year":"2003","journal-title":"Microsc Res Tech"},{"key":"key\n\t\t\t\t20170224175159_R40","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/(SICI)1098-2795(199909)54:1<24::AID-MRD4>3.0.CO;2-S","article-title":"Transmitochondrial differences and varying levels of heteroplasmy in nuclear transfer cloned cattle","volume":"54","year":"1999","journal-title":"Mol Reprod Dev"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/69\/1\/254\/10589157\/biolreprod0254.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,19]],"date-time":"2024-12-19T02:32:25Z","timestamp":1734575545000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.102.010975"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,7,1]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,7,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.102.010975","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,7,1]]}}}