{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:15:18Z","timestamp":1761707718311},"reference-count":50,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003,11,1]]},"DOI":"10.1095\/biolreprod.102.012443","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T14:30:50Z","timestamp":1098282650000},"page":"1600-1607","source":"Crossref","is-referenced-by-count":20,"title":["Regional Differences in Water Content, Collagen Content, and Collagen Degradation in the Cervix of Nonpregnant Cows"],"prefix":"10.1093","volume":"69","author":[{"given":"V.N.A.","family":"Breeveld-Dwarkasing","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"de Boer-Brouwer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.M.","family":"te Koppele","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.A.","family":"Bank","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.C.","family":"van der Weijden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.A.M.","family":"Taverne","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.M.F.","family":"van Dissel-Emiliani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224180936_R1","first-page":"22","article-title":"The comparative anatomy of the mammalian cervix","volume-title":"Biology of the Cervix","year":"1973"},{"key":"key\n\t\t\t\t20170224180936_R2","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1530\/jrf.0.1040085","article-title":"Cervical opening in relation to progesterone and oestradiol during heat in beagle bitches","volume":"104","year":"1995","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224180936_R3","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1136\/vr.101.4.70","article-title":"Clinical examination of the ovaries and cervix of the sow","volume":"101","year":"1977","journal-title":"Vet Rec"},{"key":"key\n\t\t\t\t20170224180936_R4","first-page":"20","article-title":"Anatomy of female reproduction","volume-title":"Reproduction in Farm Animals","year":"1993"},{"key":"key\n\t\t\t\t20170224180936_R5","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0945-053X(97)90012-3","article-title":"Simplified measurement of degraded collagen in tissues: application in healthy, fibrillated and osteoarthritic cartilage","volume":"16","year":"1997","journal-title":"Matrix Biol"},{"key":"key\n\t\t\t\t20170224180936_R6","first-page":"186","article-title":"Biochemische Grundlagen der Zervixreifung und Muttermondser\u00f6ffnung","volume":"198","year":"1994","journal-title":"Zeits Geburtsh Perinatol"},{"key":"key\n\t\t\t\t20170224180936_R7","doi-asserted-by":"crossref","first-page":"15","DOI":"10.3109\/03008209109006992","article-title":"Three-dimensional structures of uterine elastic fibers: scanning electron microscopic studies","volume":"27","year":"1991","journal-title":"Connect Tissue Res"},{"key":"key\n\t\t\t\t20170224180936_R8","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1530\/jrf.0.0980153","article-title":"Stimulation of collagen secretion by relaxin and effect of oestrogen on relaxin binding in uterine cervical cells of pigs","volume":"98","year":"1993","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224180936_R9","first-page":"547","article-title":"Cell populations in the human uterine cervix during midcyclic cervical opening [in German]","volume":"58","year":"1998","journal-title":"Geburtsh Frauenheilk"},{"key":"key\n\t\t\t\t20170224180936_R10","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1113\/jphysiol.1959.sp006304","article-title":"Changes in the physical properties of the uterine cervix of the rat during pregnancy","volume":"148","year":"1959","journal-title":"J Physiol"},{"key":"key\n\t\t\t\t20170224180936_R11","first-page":"57","article-title":"The anatomy of the cervix, gross and microscopic","volume-title":"Biology of the Cervix","year":"1973"},{"key":"key\n\t\t\t\t20170224180936_R12","first-page":"27","article-title":"The ultrastructure of the human cervix","volume-title":"Dilatation of the uterine cervix (connective tissue biology and clinical management)","year":"1980"},{"key":"key\n\t\t\t\t20170224180936_R13","first-page":"45","article-title":"Collagen dynamics and extensibility in the female reproductive tract","volume-title":"Dilatation of the Uterine Cervix (Connective Tissue Biology and Clinical Management)","year":"1980"},{"key":"key\n\t\t\t\t20170224180936_R14","first-page":"45","article-title":"Connective tissue alterations associated with parturition in the rabbit","volume-title":"Dilatation of the Uterine Cervix (Connective Tissue Biology and Clinical Management)","year":"1980"},{"key":"key\n\t\t\t\t20170224180936_R15","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1097\/00003081-199506000-00009","article-title":"Anatomy and physiology of cervical ripening","volume":"38","year":"1995","journal-title":"Clin Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R16","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1095\/biolreprod54.3.700","article-title":"Oxytocin receptors in bovine cervix: distribution and gene expression during the estrous cycle","volume":"54","year":"1996","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180936_R17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0921-4488(92)90070-K","article-title":"Changes in the extensibility of the ovine cervix uteri following infusion of estradiol-17\u03b2 at term","volume":"7","year":"1992","journal-title":"Small Rumin Res"},{"key":"key\n\t\t\t\t20170224180936_R18","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0002-9378(85)90311-4","article-title":"Increase in cervical extensibility during labour induced after isolation of the cervix from the uterus in pregnant ewes","volume":"151","year":"1985","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R19","doi-asserted-by":"crossref","first-page":"3004","DOI":"10.1210\/endo-125-6-3004","article-title":"Hormonal control of the cervix in pregnant gilts. II. Relaxin promotes changes in the physical properties of the cervix in ovariectomized hormone-treated pregnant gilts","volume":"125","year":"1989","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180936_R20","doi-asserted-by":"crossref","first-page":"1967","DOI":"10.1210\/endo-129-4-1967","article-title":"Hormonal control of the cervix in pregnant gilts. III. Relaxin\u2019s influence on cervical biochemical properties in ovariectomized hormone-treated pregnant gilts","volume":"129","year":"1991","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180936_R21","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1210\/endo.133.1.8319559","article-title":"Hormonal control of the cervix in pregnant gilts. IV Relaxin promotes changes in the histological characteristics of the cervix that are associated with cervical softening during late pregnancy in gilts","volume":"133","year":"1993","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180936_R22","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1016\/0002-9378(82)90111-9","article-title":"Variations in the mechanical behaviour of the rabbit cervix with endocrine state and anatomic site","volume":"143","year":"1982","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R23","first-page":"255","article-title":"Anatomic site and stretch modulus in the human cervix","volume-title":"Dilatation of the Uterine Cervix (Connective Tissue biology and Clinical Management).","year":"1980"},{"key":"key\n\t\t\t\t20170224180936_R24","first-page":"772","article-title":"In vitro analysis of muscular contractile ability and passive biomechanical properties of uterine cervical samples from nonpregnant women","volume":"77","year":"1991","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R25","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1148\/radiology.186.1.8416558","article-title":"Zonal anatomy of the cervix: correlation of MR imaging and histologic examination of hysterectomy specimens","volume":"186","year":"1993","journal-title":"Radiology"},{"key":"key\n\t\t\t\t20170224180936_R26","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1210\/endo.135.3.8070369","article-title":"Individual and combined effects of relaxin, estrogen and progesterone in ovariectomized gilts. I. Effects on the growth, softening and histological properties of the cervix","volume":"135","year":"1994","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180936_R27","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1530\/jrf.0.0810533","article-title":"Effects of monoclonal antibody against PMSG administered shortly after the preovulatory LH surge on time and number of ovulations in PMSG\/PG treated cows","volume":"81","year":"1987","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224180936_R28","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/S0006-291X(76)80180-5","article-title":"The estimation of two collagens from human dermis by interrupted gel electrophoresis","volume":"72","year":"1976","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170224180936_R29","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1006\/abio.1996.0346","article-title":"Amino acid analysis by reverse-phase high-performance liquid chromatography: improved derivatisation and detection conditions with 9-fluoromethyl chloroformate","volume":"240","year":"1996","journal-title":"Ann Biochem"},{"key":"key\n\t\t\t\t20170224180936_R30","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1136\/ard.58.1.35","article-title":"Lysylhydroxylation and nonreducible cross-linking of human supraspinatus tendon collagen: changes with age and in chronic rotator cuff tendinitis","volume":"58","year":"1999","journal-title":"Ann Rheum Dis"},{"key":"key\n\t\t\t\t20170224180936_R31","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0009-8981(67)90167-2","article-title":"Determination of hydroxyproline","volume":"18","year":"1967","journal-title":"Clin Chim Acta"},{"key":"key\n\t\t\t\t20170224180936_R32","doi-asserted-by":"crossref","first-page":"656","DOI":"10.2144\/97224bm19","article-title":"Microassay for the assessment of hydroxyproline","volume":"22","year":"1997","journal-title":"BioTechniques"},{"key":"key\n\t\t\t\t20170224180936_R33","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1016\/0002-9378(78)90003-0","article-title":"Collagen changes in the human uterine cervix at parturition","volume":"130","year":"1978","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R34","first-page":"413","article-title":"Changes in the collagen of the uterine cervix of the mouse during the oestrous cycle","volume":"55","year":"1972","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224180936_R35","first-page":"432","article-title":"Changes in the cervical function at parturition","volume":"8","year":"1977","journal-title":"Ann Rech Vet"},{"key":"key\n\t\t\t\t20170224180936_R36","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1530\/jrf.0.1130075","article-title":"Length tension relationships in the non pregnant and pregnant rat uterus and the effect of antiprogestin","volume":"113","year":"1998","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224180936_R37","first-page":"351","article-title":"The effects of pregnancy and labor on the amino acid composition of the human cervix","volume-title":"Biology of the Cervix","year":"1973"},{"key":"key\n\t\t\t\t20170224180936_R38","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/0002-9378(83)90446-5","article-title":"Ripening of the human uterine cervix related to changes in collagen, glycosaminoglycans, and collagenolytic activity","volume":"147","year":"1983","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R39","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0002-9378(80)90248-3","article-title":"Morphologic and histochemical evidence for the occurrence of collagenolysis and for the role of neutrophilic polymorphonuclear leukocytes during cervical dilatation","volume":"138","year":"1980","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R40","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1111\/j.1471-0528.1989.tb03196.x","article-title":"Changes in the connective tissue of corpus and cervix uteri during ripening and labour in term pregnancy","volume":"96","year":"1989","journal-title":"Br J Obstet Gynaecol"},{"key":"key\n\t\t\t\t20170224180936_R41","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1111\/j.1471-0528.1991.tb15391.x","article-title":"Insufficient remodeling of the uterine connective tissue in women with protracted labour","volume":"98","year":"1991","journal-title":"Br J Obstet Gynaecol"},{"key":"key\n\t\t\t\t20170224180936_R42","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S0002-9378(96)70352-6","article-title":"Cervical ripening in humans: Potential roles of estrogen, progesterone, and insulin-like growth factor-I","volume":"174","year":"1996","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R43","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0301-2115(96)02440-2","article-title":"Cervical collagen in nonpregnant women with previous cervical incompetence","volume":"67","year":"1996","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"key\n\t\t\t\t20170224180936_R44","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0029-7844(97)00245-7","article-title":"Malmst\u00f6m A, Barchan K, Eriksson HA, Ekman G. Potential roles for gonadal steroids and insulin-like growth factor I during final cervical ripening","volume":"90","year":"1997","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180936_R45","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1095\/biolreprod48.6.1348","article-title":"Influence of ovarian steroids on relaxin-induced distensibility and compositional changes in the porcine cervix","volume":"48","year":"1993","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180936_R46","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0378-4320(96)01593-X","article-title":"Relaxin and estrogen synergistically accelerate growth and development in the uterine cervix of prepubertal pig","volume":"46","year":"1997","journal-title":"Anim Reprod Sci"},{"key":"key\n\t\t\t\t20170224180936_R47","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1071\/RD02005","article-title":"Immunohistochemical distribution of oestrogen and progesterone receptors and tissue concentrations of oestrogens in the cervix of nonpregnant cows","volume":"14","year":"2002","journal-title":"Reprod Fertil Dev"},{"key":"key\n\t\t\t\t20170224180936_R48","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1002\/1529-0131(200010)43:10<2202::AID-ANR7>3.0.CO;2-E","article-title":"The increased swelling and instantaneous deformation of osteoarthritic cartilage is highly correlated with collagen degradation","volume":"43","year":"2000","journal-title":"Arthritis Rheum"},{"key":"key\n\t\t\t\t20170224180936_R49","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0304-4165(91)90250-K","article-title":"Increased hyaluronate synthesis and changes in glycosaminoglycans ratios and molecular weight of proteoglycans synthesized by cultured cervical tissue from ewes at various stages of pregnancy","volume":"1075","year":"1991","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170224180936_R50","first-page":"45","article-title":"Changes in the extracellular matrix during pregnancy and parturition","volume":"27","year":"1999","journal-title":"J Perinat Med"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/69\/5\/1600\/10588317\/biolreprod1600.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2018,10,16]],"date-time":"2018-10-16T06:20:44Z","timestamp":1539670844000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article\/2712860\/Regional"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,1]]},"references-count":50,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2003,11,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.102.012443","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,11,1]]}}}