{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:15:47Z","timestamp":1791328547591,"version":"4.3.1"},"reference-count":58,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2004,12,1]]},"DOI":"10.1095\/biolreprod.104.032201","type":"journal-article","created":{"date-parts":[[2004,10,20]],"date-time":"2004-10-20T18:41:43Z","timestamp":1098297703000},"page":"1862-1869","source":"Crossref","is-referenced-by-count":21,"title":["Altered Placental Lactogen and Leptin Expression in Placentomes from Bovine Nuclear Transfer Pregnancies1"],"prefix":"10.1093","volume":"71","author":[{"given":"Susan R.","family":"Ravelich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew N.","family":"Shelling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiva","family":"Reddy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Keelan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David N.","family":"Wells","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. James","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita S.F.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernhard H.","family":"Breier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224040016_R1","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1530\/rep.0.1220347","article-title":"Nutrient partitioning during adolescent pregnancy","volume":"122","year":"2001","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224040016_R2","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/ije\/30.1.15","article-title":"The nutritional basis of the fetal origins of adult disease","volume":"30","year":"2001","journal-title":"Int J Epidemiol"},{"key":"key\n\t\t\t\t20170224040016_R3","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1095\/biolreprod.103.023853","article-title":"Maternal growth hormone treatment from Day 35 to 80 of gestation alters nutrient partitioning in favor of uteroplacental growth in the overnourished adolescent sheep","volume":"70","year":"2004","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R4","doi-asserted-by":"crossref","first-page":"S29","DOI":"10.1016\/S0301-2115(03)00170-2","article-title":"Models of fetal growth restriction","volume":"110","year":"2003","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"key\n\t\t\t\t20170224040016_R5","first-page":"379","article-title":"Studies on experimental growth retardation in sheep. The effect of removal of endometrial caruncles on fetal size and metabolism","volume":"1","year":"1979","journal-title":"J Dev Physiol"},{"key":"key\n\t\t\t\t20170224040016_R6","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/S1071-5576(03)00134-5","article-title":"Fetal growth restriction and consequences for the offspring in animal models","volume":"10","year":"2003","journal-title":"J Soc Gynecol Invest"},{"key":"key\n\t\t\t\t20170224040016_R7","first-page":"17","article-title":"Some aspects of placental function in chronically heat-stressed ewes","volume":"9","year":"1987","journal-title":"J Dev Physiol"},{"key":"key\n\t\t\t\t20170224040016_R8","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0303-7207(98)00039-2","article-title":"Fetal growth and placental function","volume":"140","year":"1998","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224040016_R9","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.2527\/1995.7361861x","article-title":"Placental-fetal hormonal interactions: impact on fetal growth","volume":"73","year":"1995","journal-title":"J Anim Sci"},{"key":"key\n\t\t\t\t20170224040016_R10","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1042\/bst0290057","article-title":"Leptin expression in placental and fetal tissues: does leptin have a functional role?","volume":"29","year":"2001","journal-title":"Biochem Soc Trans"},{"key":"key\n\t\t\t\t20170224040016_R11","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/S0739-7240(96)00090-2","article-title":"Effect of chronic infusion of placental lactogen on ovine fetal growth in late gestation","volume":"13","year":"1996","journal-title":"Domest Anim Endocrinol"},{"key":"key\n\t\t\t\t20170224040016_R12","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/0143-4004(92)90025-O","article-title":"Current topic: the synepitheliochorial placenta of ruminants: binucleate cell fusions and hormone production","volume":"13","year":"1992","journal-title":"Placenta"},{"key":"key\n\t\t\t\t20170224040016_R13","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1002\/(SICI)1097-0029(19970701\/15)38:1\/2<88::AID-JEMT10>3.0.CO;2-A","article-title":"Structure and function in the ruminant synepitheliochorial placenta: central role of the trophoblast binucleate cell in deer","volume":"38","year":"1997","journal-title":"Microsc Res Tech"},{"key":"key\n\t\t\t\t20170224040016_R14","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.2527\/1992.7092911x","article-title":"Ruminant placental lactogens: structure and biology","volume":"70","year":"1992","journal-title":"J Anim Sci"},{"key":"key\n\t\t\t\t20170224040016_R15","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1210\/endo-99-5-1273","article-title":"Circulating placental lactogen levels in dairy and beef cattle","volume":"99","year":"1976","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224040016_R16","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1210\/edrv-12-4-329","article-title":"Clinical counterpoint: the physiology of placental lactogen in human pregnancy","volume":"12","year":"1991","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224040016_R17","first-page":"232","article-title":"Comparison of the growth promoting effects of bovine placental lactogen with bovine somatotropin.","year":"1990","journal-title":"ADSA Annual Meeting"},{"key":"key\n\t\t\t\t20170224040016_R18","first-page":"83","article-title":"The growth hormone prolactin gene family in ruminant placenta","volume":"49","year":"1995","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224040016_R19","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1095\/biolreprod63.5.1219","article-title":"Leptin in pregnancy","volume":"63","year":"2000","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R20","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1053\/plac.2001.0769","article-title":"Prospective function of placental leptin at maternal-fetal interface","volume":"23","year":"2002","journal-title":"Placenta"},{"key":"key\n\t\t\t\t20170224040016_R21","doi-asserted-by":"crossref","first-page":"R1628","DOI":"10.1152\/ajpregu.00750.2001","article-title":"Spatial and developmental regulation of leptin in fetal sheep","volume":"282","year":"2002","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"key\n\t\t\t\t20170224040016_R22","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1677\/joe.0.1690465","article-title":"Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome","volume":"169","year":"2001","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224040016_R23","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1530\/ror.0.0050018","article-title":"Placental leptin","volume":"5","year":"2000","journal-title":"Rev Reprod"},{"key":"key\n\t\t\t\t20170224040016_R24","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1038\/nm0997-1029","article-title":"Nonadipose tissue production of leptin: leptin as a novel placenta-derived hormone in humans","volume":"3","year":"1997","journal-title":"Nat Med"},{"key":"key\n\t\t\t\t20170224040016_R25","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1093\/molehr\/6.10.951","article-title":"Leptin modulates extracellular matrix molecules and metalloproteinases: possible implications for trophoblast invasion","volume":"6","year":"2000","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224040016_R26","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1385\/ENDO:19:1:65","article-title":"Possible role of placental leptin in pregnancy: a review","volume":"19","year":"2002","journal-title":"Endocrine"},{"key":"key\n\t\t\t\t20170224040016_R27","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1093\/molehr\/6.8.763","article-title":"Placental leptin in normal, diabetic and fetal growth-retarded pregnancies","volume":"6","year":"2000","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224040016_R28","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1095\/biolreprod63.6.1787","article-title":"Evidence for placental abnormality as the major cause of mortality in first-trimester somatic cell cloned bovine fetuses","volume":"63","year":"2000","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R29","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1095\/biolreprod65.1.23","article-title":"Evaluation of gestational deficiencies in cloned sheep fetuses and placentae","volume":"65","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R30","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1095\/biolreprod60.4.996","article-title":"Production of cloned calves following nuclear transfer with cultured adult mural granulosa cells","volume":"60","year":"1999","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R31","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1095\/biolreprod.103.021139","article-title":"Insulin-like growth factor-I and binding proteins 1, 2, and 3 in bovine nuclear transfer pregnancies","volume":"70","year":"2004","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R32","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1095\/biolreprod.103.020982","article-title":"Cloned cattle fetuses with the same nuclear genetics are more variable than contemporary half-siblings resulting from artificial insemination and exhibit fetal and placental growth deregulation even in the first trimester","volume":"70","year":"2004","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040016_R33","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1530\/jrf.0.1180047","article-title":"Effect of inhibitors and uncouplers of oxidative phosphorylation during compaction and blastulation of bovine embryos cultured in vitro","volume":"118","year":"2000","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224040016_R34","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0093-691X(02)01273-6","article-title":"Coordination between donor cell type and cell cycle stage improves nuclear cloning efficiency in cattle","volume":"59","year":"2003","journal-title":"Theriogenology"},{"key":"key\n\t\t\t\t20170224040016_R35","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1677\/joe.0.1320185","article-title":"Serum half-life and in vivo actions of recombinant bovine placental lactogen in the dairy cow","volume":"132","year":"1992","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224040016_R36","doi-asserted-by":"crossref","first-page":"E83","DOI":"10.1152\/ajpendo.2000.279.1.E83","article-title":"Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition","volume":"279","year":"2000","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224040016_R37","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1677\/joe.0.1700323","article-title":"Dysregulation of the adipoinsular axis\u2014a mechanism for the pathogenesis of hyperleptinemia and adipogenic diabetes induced by fetal programming","volume":"170","year":"2001","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224040016_R38","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1038\/194495a0","article-title":"Preparation of iodine-131 labelled human growth hormone of high specific activity","volume":"194","year":"1962","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224040016_R39","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/S0304-3940(02)01423-4","article-title":"Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data","volume":"339","year":"2003","journal-title":"Neurosci Lett"},{"key":"key\n\t\t\t\t20170224040016_R40","volume-title":"ABI Prism 7700 Sequence Detection System, User Bulletin 2","year":"1997"},{"key":"key\n\t\t\t\t20170224040016_R41","first-page":"0034.1","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","year":"2002","journal-title":"Genome Biol"},{"key":"key\n\t\t\t\t20170224040016_R42","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1089\/15362300260339485","article-title":"Implantation and placental development in somatic cell clone recipient cows","volume":"4","year":"2002","journal-title":"Clon Stem Cells"},{"key":"key\n\t\t\t\t20170224040016_R43","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1600-0412.2004.00277.x","article-title":"Second- and third-trimester serum levels of placental proteins in preeclampsia and small-for-gestational age pregnancies","volume":"83","year":"2004","journal-title":"Acta Obstet Gynecol Scand"},{"key":"key\n\t\t\t\t20170224040016_R44","doi-asserted-by":"crossref","first-page":"1741S","DOI":"10.1093\/jn\/133.5.1741S","article-title":"Regulation of fetal growth by the somatotrophic axis","volume":"133","year":"2003","journal-title":"J Nutr"},{"key":"key\n\t\t\t\t20170224040016_R45","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0014-2999(98)00884-X","article-title":"Expression of leptin receptor in lung: leptin as a growth factor","volume":"365","year":"1999","journal-title":"Eur J Pharmacol"},{"key":"key\n\t\t\t\t20170224040016_R46","doi-asserted-by":"crossref","first-page":"14564","DOI":"10.1073\/pnas.93.25.14564","article-title":"Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells","volume":"93","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224040016_R47","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/emm.2001.17","article-title":"Potential role of leptin in angiogenesis: leptin induces endothelial cell proliferation and expression of matrix metalloproteinases in vivo and in vitro","volume":"33","year":"2001","journal-title":"Exp Mol Med"},{"key":"key\n\t\t\t\t20170224040016_R48","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1530\/jrf.0.0760499","article-title":"Control of binucleate cell migration in the placenta of sheep and goats","volume":"76","year":"1986","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224040016_R49","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.2527\/1991.6931059x","article-title":"Relations between maternal and fetal plasma concentrations of placental lactogen and placental and fetal weights in well-fed ewes","volume":"69","year":"1991","journal-title":"J Anim Sci"},{"key":"key\n\t\t\t\t20170224040016_R50","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1053\/plac.2002.0929","article-title":"Regulatory transcription factors controlling function and differentiation of human trophoblast\u2014a review","volume":"24","year":"2003","journal-title":"Placenta"},{"key":"key\n\t\t\t\t20170224040016_R51","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1210\/rp.57.1.221","article-title":"Transcription factors underlying the development and endocrine functions of the placenta","volume":"57","year":"2002","journal-title":"Recent Prog Horm Res"},{"key":"key\n\t\t\t\t20170224040016_R52","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0022-2275(20)32561-X","article-title":"Adipose tissue ob mRNA expression in humans: discordance with plasma leptin and relationship with adipose TNFalpha expression","volume":"39","year":"1998","journal-title":"J Lipid Res"},{"key":"key\n\t\t\t\t20170224040016_R53","doi-asserted-by":"crossref","first-page":"2888","DOI":"10.1210\/endo.142.7.8227","article-title":"Leptin administration prevents spontaneous gestational diabetes in heterozygous Lepr(db\/+) mice: effects on placental leptin and fetal growth","volume":"142","year":"2001","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224040016_R54","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1136\/adc.88.9.822","article-title":"Transient hyperinsulinism associated with macrosomia, hypertrophic obstructive cardiomyopathy, hepatomegaly, and nephromegaly","volume":"88","year":"2003","journal-title":"Arch Dis Child"},{"key":"key\n\t\t\t\t20170224040016_R55","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1530\/ror.0.0030155","article-title":"Large offspring syndrome in cattle and sheep","volume":"3","year":"1998","journal-title":"Rev Reprod"},{"key":"key\n\t\t\t\t20170224040016_R56","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0093-691X(02)00935-4","article-title":"Morphology and morphometry of in vivo- and in vitro-produced bovine concepti from early pregnancy to term and association with high birth weights","volume":"58","year":"2002","journal-title":"Theriogenology"},{"key":"key\n\t\t\t\t20170224040016_R57","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1530\/rep.0.1260469","article-title":"Proliferation and apoptosis in bovine placentomes during pregnancy and around induced and spontaneous parturition as well as in cows retaining the fetal membranes","volume":"126","year":"2003","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224040016_R58","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1067\/mob.2001.117313","article-title":"Leptin in the ovine fetus correlates with fetal and placental size","volume":"185","year":"2001","journal-title":"Am J Obstet Gynecol"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/71\/6\/1862\/10644377\/biolreprod1862.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,6,26]],"date-time":"2021-06-26T18:39:56Z","timestamp":1624732796000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.104.032201"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,12,1]]},"references-count":58,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2004,12,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.104.032201","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,12,1]]}}}