{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:39:41Z","timestamp":1791225581102,"version":"4.1.0"},"reference-count":32,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,3,1]]},"DOI":"10.1095\/biolreprod.104.033647","type":"journal-article","created":{"date-parts":[[2004,11,18]],"date-time":"2004-11-18T01:25:18Z","timestamp":1100741118000},"page":"720-726","source":"Crossref","is-referenced-by-count":131,"title":["Term Human Fetal Membranes Have a Weak Zone Overlying the Lower Uterine Pole and Cervix Before Onset of Labor1"],"prefix":"10.1093","volume":"72","author":[{"given":"M.","family":"El Khwad","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Stetzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.M.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.","family":"Mercer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Arikat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.W.","family":"Redline","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.M.","family":"Mansour","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.J.","family":"Moore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224024441_R1","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1056\/NEJM199803053381006","article-title":"Premature rupture of the fetal membranes","volume":"338","year":"1998","journal-title":"New Engl J Med"},{"key":"key\n\t\t\t\t20170224024441_R2","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1095\/biolreprod60.1.176","article-title":"Amnion type IV collagen composition and metabolism: implications for membrane breakdown","volume":"60","year":"1999","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024441_R3","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1095\/biolreprod53.2.321","article-title":"Striking changes in the structure and organization of rat fetal membranes precede parturition","volume":"53","year":"1995","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024441_R4","first-page":"1971","article-title":"A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor","volume":"98","year":"1997","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224024441_R5","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S0002-9378(00)70232-8","article-title":"Increased concentration of pro-matrix metalloproteinase 9 in term fetal membranes overlying the cervix before labor: implications for membrane remodeling and rupture","volume":"182","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R6","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1111\/j.1471-0528.1994.tb11908.x","article-title":"Structural characteristic of term human fetal membranes: a novel zone of extreme morphological alteration within the rupture site","volume":"101","year":"1994","journal-title":"Br J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1093\/humrep\/14.1.237","article-title":"Structural characteristics of term human fetal membranes before labor: identification of an area of altered morphology the cervix","volume":"14","year":"1999","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170224024441_R8","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1093\/humrep\/14.11.2895","article-title":"Increased incidence of apoptosis in non-labor-affected cytotrophoblast cells in term fetal membranes the cervix","volume":"14","year":"1999","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170224024441_R9","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1067\/S0002-9378(03)00585-4","article-title":"Mapping of zones of altered morphology and chorionic connective tissue cellular phenotype in human fetal membranes (amnion and deciduas) the lower uterine pole and cervix before labor at term","volume":"189","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R10","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/0002-9378(76)90788-2","article-title":"The mechanical properties of prematurely and non-prematurely ruptured membranes. Methods and preliminary results","volume":"125","year":"1976","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R11","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/0002-9378(79)90014-0","article-title":"An in vitro model for the study of enzymatically mediated biomechanical changes in the chorioamniotic membranes","volume":"133","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R12","first-page":"87","article-title":"The effect of labor on the rheologic response of chorioamniotic membranes","volume":"60","year":"1982","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R13","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/S0002-9378(16)33077-0","article-title":"Deformation and creep in the human chorioamniotic sac","volume":"134","year":"1979","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R14","first-page":"467","article-title":"The viscoelastic nature of chorioamniotic membranes","volume":"50","year":"1977","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R15","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/0028-2243(90)90078-F","article-title":"Biomechanical analysis of human chorioamniotic membranes","volume":"34","year":"1990","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"key\n\t\t\t\t20170224024441_R16","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0028-2243(93)90086-R","article-title":"Different biomechanical properties of human fetal membranes obtained before and after delivery","volume":"48","year":"1993","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"key\n\t\t\t\t20170224024441_R17","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1007\/BF00053332","article-title":"Effect of thickness on the fracture characteristics of fetal membranes","volume":"5","year":"1994","journal-title":"J Mater Sci Mater Med"},{"key":"key\n\t\t\t\t20170224024441_R18","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1111\/j.1471-0528.1976.tb00810.x","article-title":"A study of the elasticity and tension of fetal membranes and of the relation of the area of the gestational sac to the area of the uterine cavity","volume":"83","year":"1976","journal-title":"Br J Obstet Gynaecol"},{"key":"key\n\t\t\t\t20170224024441_R19","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1111\/j.1471-0528.1980.tb04524.x","article-title":"Bursting pressure and collagen content of fetal membranes and their relation to premature rupture of the membranes","volume":"87","year":"1980","journal-title":"Br J Obstet Gynaecol"},{"key":"key\n\t\t\t\t20170224024441_R20","first-page":"263","article-title":"Full-term and prematurely ruptured fetal membranes. An ultrastructural study","volume":"220","year":"1981","journal-title":"Cell Tissue Res"},{"key":"key\n\t\t\t\t20170224024441_R21","first-page":"204","article-title":"The physical properties of fetal membranes","volume":"20","year":"1962","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R22","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1007\/BF02367090","article-title":"Resistance of fetal membranes to concentrated force applications and reconciliation of puncture and burst testing","volume":"22","year":"1994","journal-title":"Ann Biomed Eng"},{"key":"key\n\t\t\t\t20170224024441_R23","first-page":"672","article-title":"Physical properties of the chorion throughout gestation","volume":"187","year":"2003","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R24","first-page":"S9","article-title":"The roles of tissue inhibitors of metalloproteinases in tissue remodeling and cell growth","volume":"20","year":"1996","journal-title":"Int J Obes Relat Metab Disord"},{"key":"key\n\t\t\t\t20170224024441_R25","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1095\/biolreprod53.2.339","article-title":"92-kDa gelatinase (matrix metalloproteinase-9) is induced in rat amnion immediately before parturition","volume":"53","year":"1995","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024441_R26","first-page":"148","article-title":"3rd 92-kd type IV collagenase (matrix metalloproteinase-9) activity in human amniochorion increases with labor","volume":"146","year":"1995","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t20170224024441_R27","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/S0002-9378(97)70260-6","article-title":"Collagenolytic enzymes (gelatinases) and their inhibitors in human amniochorionic membrane","volume":"177","year":"1997","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R28","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1067\/mob.2000.107330","article-title":"Programmed cell death (apoptosis) as a possible pathway to metalloproteinase activation and fetal membrane degradation in premature rupture of membranes","volume":"182","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R29","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1023\/A:1020362519981","article-title":"Screening of novel matrix metalloproteinases (MMPs) in human fetal membranes","volume":"19","year":"2002","journal-title":"J Assist Reprod Genet"},{"key":"key\n\t\t\t\t20170224024441_R30","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/molehr\/8.4.399","article-title":"Use of cDNA arrays to generate differential expression profiles for inflammatory genes in human gestational membranes delivered at term and preterm","volume":"8","year":"2002","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224024441_R31","first-page":"590","article-title":"Bacteria and inflammatory cells reduce chorioamniotic membrane integrity and tensile strength","volume":"74","year":"1989","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024441_R32","first-page":"851","article-title":"Matrix metalloprotienase-9 and tensile strength of fetal membranes in uncomplicated labor","volume":"95","year":"2000","journal-title":"Obstet Gynecol"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/72\/3\/720\/10564204\/biolreprod0720.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,25]],"date-time":"2017-08-25T00:18:47Z","timestamp":1503620327000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.104.033647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3,1]]},"references-count":32,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005,3,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.104.033647","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,3,1]]}}}