{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T03:16:36Z","timestamp":1761707796909},"reference-count":54,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,11,1]]},"DOI":"10.1095\/biolreprod.105.040238","type":"journal-article","created":{"date-parts":[[2005,6,23]],"date-time":"2005-06-23T01:26:42Z","timestamp":1119490002000},"page":"872-880","source":"Crossref","is-referenced-by-count":26,"title":["Immunolocalization and Regulation of Cystatin 12 in Mouse Testis and Epididymis1"],"prefix":"10.1093","volume":"73","author":[{"given":"Ying","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Crystal A.","family":"Putnam-Lawson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Knapp-Hoch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick J.","family":"Friel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Debra","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randy","family":"Hively","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Griswold","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224024804_R1","first-page":"1363","article-title":"The cystatins: a diverse superfamily of cysteine peptidase inhibitors","volume":"45","year":"1986","journal-title":"Biomed Biochim Acta"},{"key":"key\n\t\t\t\t20170224024804_R2","first-page":"71","article-title":"Cystatins in health and disease","volume":"377","year":"1996","journal-title":"Biol Chem Hoppe Seyler"},{"key":"key\n\t\t\t\t20170224024804_R3","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0014-5793(91)80804-C","article-title":"The cystatins: protein inhibitors of cysteine proteinases","volume":"285","year":"1991","journal-title":"FEBS Lett"},{"key":"key\n\t\t\t\t20170224024804_R4","doi-asserted-by":"crossref","first-page":"10853","DOI":"10.1074\/jbc.272.16.10853","article-title":"Cystatin E is a novel human cysteine proteinase inhibitor with structural resemblance to family 2 cystatins","volume":"272","year":"1997","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224024804_R5","doi-asserted-by":"crossref","first-page":"24797","DOI":"10.1074\/jbc.273.38.24797","article-title":"Cystatin F is a glycosylated human low molecular weight cysteine proteinase inhibitor","volume":"273","year":"1998","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224024804_R6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0303-7207(02)00408-2","article-title":"A new subgroup of the family 2 cystatins","volume":"200","year":"2003","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224024804_R7","first-page":"1653","article-title":"The CRES gene: a unique testis-regulated gene related to the cystatin family is highly restricted in its expression to the proximal region of the mouse epididymis","volume":"6","year":"1992","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224024804_R8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1002\/mrd.1080410107","article-title":"Transient appearance of CRES protein during spermatogenesis and caput epididymal sperm maturation","volume":"41","year":"1995","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224024804_R9","doi-asserted-by":"crossref","first-page":"14208","DOI":"10.1073\/pnas.95.24.14208","article-title":"Testatin: a cystatin-related gene expressed during early testis development","volume":"95","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224024804_R10","doi-asserted-by":"crossref","first-page":"1872","DOI":"10.1095\/biolreprod.102.003368","article-title":"Identification and characterization of testis- and epididymis-specific genes: cystatin SC and cystatin TE-1","volume":"67","year":"2002","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R11","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1210\/en.2002-220890","article-title":"Cres2 and Cres3: new members of the cystatin-related epididymal spermatogenic subgroup of family 2 cystatins","volume":"144","year":"2003","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R12","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1095\/biolreprod.102.014100","article-title":"Cystatin E1 and E2, new members of male reproductive tract subgroup within cystatin type 2 family","volume":"69","year":"2003","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R13","doi-asserted-by":"crossref","first-page":"2787","DOI":"10.1210\/endo.143.7.8925","article-title":"Cystatin 11: a new member of the cystatin type 2 family","volume":"143","year":"2002","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R14","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0378-1119(00)00030-5","article-title":"Molecular cloning, chromosome mapping and characterization of a testis- specific cystatin-like cDNA, cystatin T","volume":"245","year":"2000","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170224024804_R15","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1089\/dna.1994.13.97","article-title":"The human type 2 cystatin gene family consists of eight to nine members, with at least seven genes clustered at a single locus on human chromosome 20","volume":"13","year":"1994","journal-title":"DNA Cell Biol"},{"key":"key\n\t\t\t\t20170224024804_R16","doi-asserted-by":"crossref","first-page":"2593","DOI":"10.1002\/j.1460-2075.1988.tb03109.x","article-title":"The 2.0 A X-ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases","volume":"7","year":"1988","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t20170224024804_R17","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1210\/en.2002-220997","article-title":"The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2","volume":"144","year":"2003","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R18","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.1210\/endo.140.6.6777","article-title":"Cystatin-related epididymal spermatogenic protein colocalizes with luteinizing hormone-beta protein in mouse anterior pituitary gonadotropes","volume":"140","year":"1999","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R19","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1095\/biolreprod60.6.1542","article-title":"Immunolocalization of CRES (cystatin-related epididymal spermatogenic) protein in the acrosomes of mouse spermatozoa","volume":"60","year":"1999","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R20","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1095\/biolreprod.102.003970","article-title":"Identification and characterization of cystatin-related epididymal spermatogenic protein in human spermatozoa: localization in the equatorial segment","volume":"67","year":"2002","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R21","first-page":"777","article-title":"A cystatin-related gene, testatin\/cresp, shows male-specific expression in germ and somatic cells from the initial stage of murine gonadal sex-differentiation","volume":"43","year":"1999","journal-title":"Int J Dev Biol"},{"key":"key\n\t\t\t\t20170224024804_R22","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0303-7207(90)90205-M","article-title":"Analysis of major androgen-regulated cDNA clones from the rat epididymis","volume":"74","year":"1990","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224024804_R23","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1042\/bj2810203","article-title":"Structure and expression of the rat epididymal secretory protein I gene. An androgen-regulated member of the lipocalin superfamily with a rare splice donor site","volume":"281","year":"1992","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224024804_R24","doi-asserted-by":"crossref","first-page":"2971","DOI":"10.1210\/endo.139.6.6074","article-title":"Molecular cloning and hormonal regulation of a murine epididymal retinoic acid-binding protein messenger ribonucleic acid","volume":"139","year":"1998","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R25","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1210\/endo-115-5-1925","article-title":"On the androgen microenvironment of maturing spermatozoa","volume":"115","year":"1984","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R26","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/j.1939-4640.1991.tb01602.x","article-title":"Endocytosis of androgen-binding protein, clusterin, and transferrin in the efferent ducts and epididymis of the ram","volume":"12","year":"1991","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224024804_R27","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1038\/37352","article-title":"A role for oestrogens in the male reproductive system","volume":"390","year":"1997","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224024804_R28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1095\/biolreprod58.1.197","article-title":"Regulation of gamma-glutamyl transpeptidase catalytic activity and protein level in the initial segment of the rat epididymis by testicular factors: role of basic fibroblast growth factor","volume":"58","year":"1998","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R29","first-page":"195","volume-title":"The Sertoli Cell,","year":"1993","edition":"1st ed"},{"key":"key\n\t\t\t\t20170224024804_R30","first-page":"121","volume-title":"Sertoli Cell Biology,","year":"2005","edition":"1st ed"},{"key":"key\n\t\t\t\t20170224024804_R31","first-page":"217","volume-title":"The Sertoli Cell,","year":"1993","edition":"1st ed"},{"key":"key\n\t\t\t\t20170224024804_R32","first-page":"189","volume-title":"The Physiology of Reproduction","year":"1994","edition":"2nd ed"},{"key":"key\n\t\t\t\t20170224024804_R33","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1002\/jemt.10314","article-title":"Acquisition of volume regulatory response of sperm upon maturation in the epididymis and the role of the cytoplasmic droplet","volume":"61","year":"2003","journal-title":"Microsc Res Tech"},{"key":"key\n\t\t\t\t20170224024804_R34","doi-asserted-by":"crossref","first-page":"35P","DOI":"10.1042\/bj1110035Pa","article-title":"Lysosomal enzymes in bull and ram semen","volume":"111","year":"1969","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224024804_R35","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1530\/jrf.0.0300105","article-title":"Glycolytic enzymes in the spermatozoa and cytoplasmic droplets of bull, boar and ram, and their leakage after shock","volume":"30","year":"1972","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224024804_R36","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1002\/j.1939-4640.1996.tb01759.x","article-title":"Mouse epididymal sperm contain active P450 aromatase which decreases as sperm traverse the epididymis","volume":"17","year":"1996","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224024804_R37","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1095\/biolreprod66.5.1219","article-title":"Comparison, characterization, and identification of proteases and protease inhibitors in epididymal fluids of domestic mammals. Matrix metalloproteinases are major fluid gelatinases","volume":"66","year":"2002","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R38","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1172\/JCI10768","article-title":"Disruption of the protein C inhibitor gene results in impaired spermatogenesis and male infertility","volume":"106","year":"2000","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224024804_R39","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1095\/biolreprod59.2.364","article-title":"Curry TE Jr. Pattern of messenger ribonucleic acid expression of tissue inhibitors of metalloproteinases (TIMPs) during testicular maturation in male mice lacking a functional TIMP-1 gene","volume":"59","year":"1998","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R40","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0378-1119(01)00462-0","article-title":"Cloning and sequencing of human Eppin: a novel family of protease inhibitors expressed in the epididymis and testis","volume":"270","year":"2001","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170224024804_R41","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1095\/biolreprod20.2.269","article-title":"Collection of rete testis fluid from rats without previous efferent duct ligation","volume":"20","year":"1979","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R42","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1091\/mbc.6.7.851","article-title":"The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse","volume":"6","year":"1995","journal-title":"Mol Biol Cell"},{"key":"key\n\t\t\t\t20170224024804_R43","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1042\/bj3480021","article-title":"Cloning and characterization of ADAM28: evidence for autocatalytic pro-domain removal and for cell surface localization of mature ADAM28","volume":"348","year":"2000","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224024804_R44","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1095\/biolreprod52.2.226","article-title":"Regulation of epididymal epithelial cell functions","volume":"52","year":"1995","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R45","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1095\/biolreprod52.5.1012","article-title":"Protein synthesis and secretion by the rat caput epididymidis in vivo: influence of the luminal microenvironment","volume":"52","year":"1995","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024804_R46","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1002\/j.1939-4640.1998.tb02054.x","article-title":"Androgen binding protein secretion and endocytosis by principal cells in the adult rat epididymis and during postnatal development","volume":"19","year":"1998","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224024804_R47","first-page":"47","article-title":"Testicular regulation of epididymal gene expression","volume":"53","year":"1998","journal-title":"J Reprod Fertil Suppl"},{"key":"key\n\t\t\t\t20170224024804_R48","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1530\/jrf.0.0500327","article-title":"Effect of efferent duct ligation, gonadectomy and testosterone replacement on epididymal contractility in the rat","volume":"50","year":"1977","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224024804_R49","doi-asserted-by":"crossref","first-page":"1618","DOI":"10.1210\/endo-99-6-1618","article-title":"Steroids in fluids and sperm entering and leaving the bovine epididymis, epididymal tissue, and accessory sex gland secretions","volume":"99","year":"1976","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R50","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/j.1939-4640.2002.tb02345.x","article-title":"Localization of androgen and estrogen receptors in adult male mouse reproductive tract","volume":"23","year":"2002","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224024804_R51","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1530\/ror.0.0050084","article-title":"Oestrogen in fluid transport in efferent ducts of the male reproductive tract","volume":"5","year":"2000","journal-title":"Rev Reprod"},{"key":"key\n\t\t\t\t20170224024804_R52","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/j.1939-4640.2000.tb03282.x","article-title":"Morphologic changes in efferent ductules and epididymis in estrogen receptor-alpha knockout mice","volume":"21","year":"2000","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224024804_R53","doi-asserted-by":"crossref","first-page":"4796","DOI":"10.1210\/endo.137.11.8895349","article-title":"Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility","volume":"137","year":"1996","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224024804_R54","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1095\/biolreprod63.6.1873","article-title":"Estrogen receptor alpha has a functional role in the mouse rete testis and efferent ductules","volume":"63","year":"2000","journal-title":"Biol Reprod"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/73\/5\/872\/10563125\/biolreprod0872.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,1,27]],"date-time":"2024-01-27T04:12:50Z","timestamp":1706328770000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.105.040238"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,11,1]]},"references-count":54,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005,11,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.105.040238","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005,11,1]]}}}