{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T14:51:14Z","timestamp":1758120674686},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,7,1]]},"DOI":"10.1095\/biolreprod.105.048363","type":"journal-article","created":{"date-parts":[[2006,3,9]],"date-time":"2006-03-09T02:04:58Z","timestamp":1141869898000},"page":"24-33","source":"Crossref","is-referenced-by-count":6,"title":["Daily Immunoactive and Bioactive Human Chorionic Gonadotropin Profiles in Periimplantation Urine Samples1"],"prefix":"10.1093","volume":"75","author":[{"given":"Pete","family":"Lohstroh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongxing","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Gee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bill","family":"Lasley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224040022_R1","first-page":"1557","article-title":"Reproductive toxicology: current and future directions","volume":"62","year":"2001","journal-title":"Biochem Pharm"},{"key":"key\n\t\t\t\t20170224040022_R2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1056\/NEJM198807283190401","article-title":"Incidence of early loss of pregnancy","volume":"319","year":"1988","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170224040022_R3","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0065-2660(08)60332-6","article-title":"The origin of numerical chromosome abnormalities","volume":"33","year":"1995","journal-title":"Adv Genet"},{"key":"key\n\t\t\t\t20170224040022_R4","article-title":"Reproductive and developmental toxicants. Regulatory actions provide uncertain protection","author":"U.S. General Accounting Office","year":"1991","journal-title":"GAO\/PEMD-92\u20133"},{"key":"key\n\t\t\t\t20170224040022_R5","volume-title":"Developmental Toxicology","year":"1994"},{"key":"key\n\t\t\t\t20170224040022_R6","first-page":"883","article-title":"Prospective monitoring of early fetal loss and clinical spontaneous abortion among female semiconductor workers","volume":"8","year":"1995","journal-title":"Am J Ind Med"},{"key":"key\n\t\t\t\t20170224040022_R7","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1002\/ajim.4700280612","article-title":"Epidemiologic methods for prospective assessment of menstrual cycle and reproductive characteristics in female semiconductor workers","volume":"28","year":"1995","journal-title":"Am J Ind Med"},{"key":"key\n\t\t\t\t20170224040022_R8","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/S0015-0282(02)04694-0","article-title":"Conception, early pregnancy loss, and time to clinical pregnancy: a population-based prospective study","volume":"79","year":"2003","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224040022_R9","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/aje\/kwh128","article-title":"et al Paternal smoking and pregnancy loss: a prospective study using a biomarker of pregnancy","volume":"159","year":"2004","journal-title":"Am J Epidemiol"},{"key":"key\n\t\t\t\t20170224040022_R10","first-page":"194","volume-title":"Essential Reproduction","year":"2000","edition":"5th ed"},{"key":"key\n\t\t\t\t20170224040022_R11","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1210\/en.2002-220922","article-title":"The central role of human chorionic gonadotrophin in the formation of human placental syncytium","volume":"144","year":"2003","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224040022_R12","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1146\/annurev.bi.50.070181.002341","article-title":"Glycoprotein hormones: structure and function","volume":"50","year":"1981","journal-title":"Annu Rev Biochem"},{"key":"key\n\t\t\t\t20170224040022_R13","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1002\/(SICI)1097-0223(199812)18:12<1232::AID-PD439>3.0.CO;2-Z","article-title":"Differential urinary gonadotrophin profiles in early pregnancy and early pregnancy loss","volume":"18","year":"1998","journal-title":"Prenat Diagn"},{"key":"key\n\t\t\t\t20170224040022_R14","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1093\/humrep\/deh702","article-title":"free HCG beta subunit, and HCG beta core fragment: longitudinal patterns in urine during early pregnancy","volume":"20","year":"2005","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170224040022_R15","doi-asserted-by":"crossref","first-page":"2233","DOI":"10.1093\/clinchem\/43.12.2233","article-title":"Immunoassay of human chorionic gonadotrophin, its free subunits, and metabolites","volume":"43","year":"1997","journal-title":"Clin Chem"},{"key":"key\n\t\t\t\t20170224040022_R16","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.1095\/biolreprod49.6.1310","article-title":"Luminesence luteinizing hormone\/choriogonadotropin (LH\/CG) cellular bioassay: measurement of serum bioactive LH\/CG during pregnancy in human and macaque","volume":"49","year":"1993","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224040022_R17","first-page":"204","article-title":"Characterization of human chorionic gonadotrophin peptide variants with a radioreceptor assay using recombinant human luteinizing hormone\/chorionic gonadotropin receptors","volume":"3","year":"1997","journal-title":"Early Pregnancy"},{"key":"key\n\t\t\t\t20170224040022_R18","first-page":"213","article-title":"Characterization of human chorionic gonadotrophin in normal and abnormal pregnancies","volume":"3","year":"1997","journal-title":"Early Pregnancy"},{"key":"key\n\t\t\t\t20170224040022_R19","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1016\/S0015-0282(02)02998-9","article-title":"Urinary follicle-stimulating hormone peak as a biomarker for estimating the day of ovulation","volume":"77","year":"2002","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224040022_R20","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/S0015-0282(97)00475-5","article-title":"Enzyme immunoassay method for total urinary follicle-stimulating hormone (FSH) beta and its application for measurement of total urinary FSH","volume":"69","year":"1998","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224040022_R21","first-page":"1222","article-title":"Jr, Overstreet JW, Samuels SJ, Boyers SP, Canfield RE, O'Connor JF, Hanson FW, Lasley BL, Prospective assessment of early fetal loss using an immunoenzymometric screening assay for detection of urinary human chorionic gonadotropin","volume":"57","year":"1992","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224040022_R22","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/j.fertnstert.2004.10.038","article-title":"HCG secretion and excretion during early pregnancy","volume":"83","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224040022_R23","first-page":"793","article-title":"Hormonal profiles of natural conception cycles ending in early, unrecognized pregnancy loss","volume":"4","year":"1991","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224040022_R24","first-page":"1796","article-title":"Time of implantation of the conceptus and loss of pregnancy","volume":"340","year":"2001","journal-title":"N Engl J Med"},{"key":"key\n\t\t\t\t20170224040022_R25","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1016\/S0021-9258(19)81628-9","article-title":"Site specificity of the chorionic gonadotropin N-linked oligosaccharides in signal transduction","volume":"264","year":"1989","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224040022_R26","doi-asserted-by":"crossref","first-page":"21613","DOI":"10.1016\/S0021-9258(20)80585-7","article-title":"Site-directed alanine mutagenesis of Phe33, Arg35, and Arg42-Ser43-Lys44 in the human gonadotropin alpha-subunit","volume":"268","year":"1993","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224040022_R27","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1210\/endo.134.4.7511092","article-title":"A region in the human glycoprotein hormone alpha-subunit important in holoprotein formation and receptor binding","volume":"134","year":"1994","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224040022_R28","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0303-7207(03)00075-3","article-title":"Activation of the luteinizing hormone receptor in the extracellular domain","volume":"202","year":"2003","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224040022_R29","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1677\/joe.0.1720497","article-title":"Differential expression of human chorionic gonadotropin (hCG) glycosylation isoforms in failing and continuing pregnancies: preliminary characterization of the hyperglycosylated hCG epitope","volume":"172","year":"2002","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224040022_R30","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1210\/mend.16.7.0871","article-title":"Evolution of glycoprotein hormone subunit genes in bilateral metazoan: identification of two novel human glycoprotein hormone subunit family genes, GPA2 and GPB5","volume":"16","year":"2002","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224040022_R31","doi-asserted-by":"crossref","first-page":"1445","DOI":"10.1172\/JCI0214340","article-title":"Thyrostimulin, a heterodimer of two new human glycoprotein subunits, activates the thyroid-stimulating hormone receptor","volume":"109","year":"2002","journal-title":"J Clin Invest"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/75\/1\/24\/10565052\/biolreprod0024.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,3]],"date-time":"2024-02-03T07:18:02Z","timestamp":1706944682000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.105.048363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,7,1]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2006,7,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.105.048363","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,7,1]]}}}