{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T23:46:50Z","timestamp":1790725610283,"version":"4.1.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,5,1]]},"DOI":"10.1095\/biolreprod.108.070425","type":"journal-article","created":{"date-parts":[[2009,1,15]],"date-time":"2009-01-15T03:53:09Z","timestamp":1231991589000},"page":"928-934","source":"Crossref","is-referenced-by-count":26,"title":["Progesterone-Regulated Caspase 3 Action in the Mouse May Play a Role in Uterine Quiescence During Pregnancy Through Fragmentation of Uterine Myocyte Contractile Proteins"],"prefix":"10.1093","volume":"80","author":[{"given":"Pancharatnam","family":"Jeyasuria","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaime","family":"Wetzel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Bradley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalpana","family":"Subedi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer C.","family":"Condon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224024828_R01","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/0002-9378(84)90677-X","article-title":"Oxytocin receptors in the human uterus during pregnancy and parturition","volume":"150","year":"1984","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024828_R02","first-page":"972","article-title":"Labor induction in women at term with mifepristone (RU 486): a double-blind, randomized, placebo-controlled study","volume":"80","year":"1992","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024828_R03","doi-asserted-by":"crossref","first-page":"C168","DOI":"10.1152\/ajpcell.1978.235.5.C168","article-title":"Possible role of gap junctions in activation of myometrium during parturition","volume":"235","year":"1978","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20170224024828_R04","first-page":"514","article-title":"Endocrine and paracrine regulation of birth at term and preterm","volume":"21","year":"2000","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224024828_R05","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1097\/01.AOG.0000160432.95395.8f","article-title":"17 Hydroxyprogesterone for the prevention of preterm delivery","volume":"105","year":"2005","journal-title":"Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024828_R06","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1210\/me.2005-0242","article-title":"Up-regulation of the progesterone receptor (PR)-C isoform in laboring myometrium by activation of nuclear factor-kappaB may contribute to the onset of labor through inhibition of PR function","volume":"20","year":"2006","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224024828_R07","doi-asserted-by":"crossref","first-page":"9518","DOI":"10.1073\/pnas.1633616100","article-title":"A decline in the levels of progesterone receptor coactivators in the pregnant uterus at term may antagonize progesterone receptor function and contribute to the initiation of parturition","volume":"100","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224024828_R08","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1210\/jcem.87.6.8609","article-title":"Progesterone withdrawal and estrogen activation in human parturition are coordinated by progesterone receptor A expression in the myometrium","volume":"87","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224024828_R09","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1093\/molehr\/7.9.875","article-title":"Interactions between progesterone receptor isoforms in myometrial cells in human labour","volume":"7","year":"2001","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224024828_R10","first-page":"981","article-title":"The parturition defect in steroid 5alpha-reductase type 1 knockout mice is due to impaired cervical ripening","volume":"13","year":"1999","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224024828_R11","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1095\/biolreprod55.5.992","article-title":"Induction of preterm birth in mice by RU486","volume":"55","year":"1996","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024828_R12","doi-asserted-by":"crossref","first-page":"6252","DOI":"10.1073\/pnas.092022999","article-title":"Functional consequences of caspase activation in cardiac myocytes","volume":"99","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224024828_R13","doi-asserted-by":"crossref","first-page":"1770","DOI":"10.1152\/japplphysiol.01288.2005","article-title":"Caspase activation contributes to endotoxin-induced diaphragm weakness","volume":"100","year":"2006","journal-title":"J Appl Physiol"},{"key":"key\n\t\t\t\t20170224024828_R14","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/j.1464-410X.2005.05855.x","article-title":"Effect of glycine on recovery of bladder smooth muscle contractility after acute urinary retention in rats","volume":"96","year":"2005","journal-title":"BJU Int"},{"key":"key\n\t\t\t\t20170224024828_R15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/1477-7827-1-44","article-title":"Apoptosis in uterine epithelium and decidua in response to implantation: evidence for two different pathways","volume":"1","year":"2003","journal-title":"Reprod Biol Endocrinol"},{"key":"key\n\t\t\t\t20170224024828_R16","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1095\/biolreprod.105.048124","article-title":"Myometrial apoptosis: activation of the caspase cascade in the pregnant rat myometrium at midgestation","volume":"74","year":"2006","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024828_R17","first-page":"660","article-title":"Apoptosis and Fas expression in human fetal membranes","volume":"83","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224024828_R18","first-page":"1508","article-title":"Stability of housekeeping gene expression in the rat retina during exposure to cyclic hyperoxia","volume":"13","year":"2007","journal-title":"Mol Vis"},{"key":"key\n\t\t\t\t20170224024828_R19","doi-asserted-by":"crossref","first-page":"202","DOI":"10.2144\/99262bm05","article-title":"Extraction of nuclear proteins from striated muscle tissue","volume":"26","year":"1999","journal-title":"Biotechniques"},{"key":"key\n\t\t\t\t20170224024828_R20","doi-asserted-by":"crossref","first-page":"2423","DOI":"10.1038\/sj.onc.1202558","article-title":"Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis","volume":"18","year":"1999","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170224024828_R21","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1126\/science.3283939","article-title":"The steroid and thyroid hormone receptor superfamily","volume":"240","year":"1988","journal-title":"Science"},{"key":"key\n\t\t\t\t20170224024828_R22","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1177\/1933719107306229","article-title":"Contractility and calcium signaling of human myometrium are profoundly affected by cholesterol manipulation: implications for labor?","volume":"14","year":"2007","journal-title":"Reprod Sci"},{"key":"key\n\t\t\t\t20170224024828_R23","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/0002-9378(90)91216-Y","article-title":"Gestational changes in mechanical properties of skinned muscle tissues of human myometrium","volume":"163","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224024828_R24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/0014-2999(95)00089-4","article-title":"Gestational changes in oxytocin- and endothelin-1-induced contractility of pregnant rat myometrium","volume":"278","year":"1995","journal-title":"Eur J Pharmacol"},{"key":"key\n\t\t\t\t20170224024828_R25","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S1095-6433(98)10118-6","article-title":"Increased contractility of rat uterine smooth muscle at the end of pregnancy","volume":"121","year":"1998","journal-title":"Comp Biochem Physiol A Mol Integr Physiol"},{"key":"key\n\t\t\t\t20170224024828_R26","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1172\/JCI116564","article-title":"Contractile elements and myosin light chain phosphorylation in myometrial tissue from nonpregnant and pregnant women","volume":"92","year":"1993","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224024828_R27","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1089\/089771502753754073","article-title":"Caspase 3-mediated cleavage of amyloid precursor protein and formation of amyloid Beta peptide in traumatic axonal injury","volume":"19","year":"2002","journal-title":"J Neurotrauma"},{"key":"key\n\t\t\t\t20170224024828_R28","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1523\/JNEUROSCI.20-08-02825.2000","article-title":"Cytochrome c release and caspase activation in traumatic axonal injury","volume":"20","year":"2000","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170224024828_R29","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1006\/exnr.2000.7523","article-title":"Rapid upregulation of caspase 3 in rat spinal cord after injury: mRNA, protein, and cellular localization correlates with apoptotic cell death","volume":"166","year":"2000","journal-title":"Exp Neurol"},{"key":"key\n\t\t\t\t20170224024828_R30","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1095\/biolreprod.105.040006","article-title":"Expression and localization of alpha-smooth muscle and gamma-actins in the pregnant rat myometrium","volume":"73","year":"2005","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224024828_R31","doi-asserted-by":"crossref","first-page":"25805","DOI":"10.1074\/jbc.M001680200","article-title":"Cleavage of the actin-capping protein alpha-adducin at Asp-Asp-Ser-Asp633-Ala by caspase 3 is preceded by its phosphorylation on serine 726 in cisplatin-induced apoptosis of renal epithelial cells","volume":"275","year":"2000","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224024828_R32","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1006\/bbrc.1997.7126","article-title":"Bradykinin induces actin reorganization and enhances cell motility in HaCaT keratinocytes","volume":"237","year":"1997","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170224024828_R33","doi-asserted-by":"crossref","first-page":"2051","DOI":"10.1089\/10430340152677403","article-title":"Blocking caspase-activated apoptosis improves contractility in failing myocardium","volume":"12","year":"2001","journal-title":"Hum Gene Ther"},{"key":"key\n\t\t\t\t20170224024828_R34","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1016\/S0735-1097(01)01670-9","article-title":"Inhibition of caspase 3 improves contractile recovery of stunned myocardium, independent of apoptosis-inhibitory effects","volume":"38","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"key\n\t\t\t\t20170224024828_R35","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1016\/S0092-8674(03)00422-7","article-title":"Apoptotic cells induce migration of phagocytes via caspase 3-mediated release of a lipid attraction signal","volume":"113","year":"2003","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170224024828_R36","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S1097-2765(04)00237-0","article-title":"Clearance of apoptotic cells: getting rid of the corpses","volume":"14","year":"2004","journal-title":"Mol Cell"},{"issue":"(pt 1)","key":"key\n\t\t\t\t20170224024828_R37","first-page":"1","article-title":"Caspases: the executioners of apoptosis","volume":"326","year":"1997","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224024828_R38","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1038\/ncpcardio0710","article-title":"Mechanisms of disease: apoptosis in heart failure\u2014seeing hope in death","volume":"3","year":"2006","journal-title":"Nat Clin Pract Cardiovasc Med"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/80\/5\/928\/10572337\/biolreprod0928.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,17]],"date-time":"2019-05-17T08:08:06Z","timestamp":1558080486000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article\/2557786\/Progesterone-Regulated"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5,1]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2009,5,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.108.070425","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,5,1]]}}}