{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:26:13Z","timestamp":1792653973617,"version":"4.5.0"},"reference-count":62,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,8,1]]},"DOI":"10.1095\/biolreprod.111.091769","type":"journal-article","created":{"date-parts":[[2011,4,21]],"date-time":"2011-04-21T04:44:31Z","timestamp":1303361071000},"page":"386-396","source":"Crossref","is-referenced-by-count":166,"title":["Postnatal Deletion of Wnt7a Inhibits Uterine Gland Morphogenesis and Compromises Adult Fertility in Mice1"],"prefix":"10.1093","volume":"85","author":[{"given":"Kathrin A.","family":"Dunlap","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justyna","family":"Filant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanako","family":"Hayashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"III","given":"Edmund B.","family":"Rucker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwonhwa","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian Min","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard R.","family":"Behringer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franco J.","family":"DeMayo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Lydon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Wook","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas E.","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224022137_R01","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0074-7696(08)60088-1","article-title":"Epithelial-stromal interactions in development of the urogenital tract","volume":"47","year":"1976","journal-title":"Int Rev Cytol"},{"key":"key\n\t\t\t\t20170224022137_R02","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0045-6039(85)90481-6","article-title":"Stromal-epithelial interactions in adult organs","volume":"17","year":"1985","journal-title":"Cell Differ"},{"key":"key\n\t\t\t\t20170224022137_R03","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/aja.1001860102","article-title":"Histologic, morphometric, and immunocytochemical analysis of myometrial development in rats and mice: I. Normal development","volume":"186","year":"1989","journal-title":"Am J Anat"},{"key":"key\n\t\t\t\t20170224022137_R04","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/nrg1225","article-title":"Developmental genetics of the female reproductive tract in mammals","volume":"4","year":"2003","journal-title":"Nat Rev Genet"},{"key":"key\n\t\t\t\t20170224022137_R05","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/jb\/mvi087","article-title":"Development of the mammalian female reproductive tract","volume":"137","year":"2005","journal-title":"J Biochem (Tokyo"},{"key":"key\n\t\t\t\t20170224022137_R06","first-page":"85","article-title":"Comparative developmental biology of the mammalian uterus.","volume-title":"Current Topics in Developmental Biology","year":"2005"},{"key":"key\n\t\t\t\t20170224022137_R07","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1095\/biolreprod65.5.1311","article-title":"Developmental biology of uterine glands","volume":"65","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R08","first-page":"287","article-title":"Uterine differentiation as a foundation for subsequent fertility","volume":"54","year":"1999","journal-title":"J Reprod Fertil Suppl"},{"key":"key\n\t\t\t\t20170224022137_R09","first-page":"99","article-title":"Early uterine development in pigs","volume":"48","year":"1993","journal-title":"J Reprod Fertil Suppl"},{"key":"key\n\t\t\t\t20170224022137_R10","doi-asserted-by":"crossref","first-page":"2229","DOI":"10.1210\/endo-117-5-2229","article-title":"The postnatal ontogeny of rat uterine glands and age-related effects of 17beta-estradiol","volume":"117","year":"1985","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224022137_R11","doi-asserted-by":"crossref","first-page":"1870","DOI":"10.1095\/biolreprod.103.026336","article-title":"Gene expression profiling of neonatal mouse uterine development","volume":"70","year":"2004","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R12","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1095\/biolreprod.109.083154","article-title":"Foxa2 is essential for mouse endometrial gland development and fertility","volume":"83","year":"2010","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R13","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1530\/rep.0.1240289","article-title":"Evidence that absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation","volume":"124","year":"2002","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224022137_R14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0303-7207(99)00170-7","article-title":"Wnt genes and endocrine disruption of the female reproductive tract: a genetic approach","volume":"158","year":"1999","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224022137_R15","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1210\/er.2003-0020","article-title":"Molecular cues to implantation","volume":"25","year":"2004","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224022137_R16","article-title":"Uterine glands.","volume-title":"Branching Morphogenesis","year":"2005"},{"key":"key\n\t\t\t\t20170224022137_R17","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1101\/gad.14.15.1837","article-title":"Wnt signaling and cancer","volume":"14","year":"2000","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20170224022137_R18","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1038\/nrm2717","article-title":"Proximal events in Wnt signal transduction","volume":"10","year":"2009","journal-title":"Nat Rev Mol Cell Biol"},{"key":"key\n\t\t\t\t20170224022137_R19","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1038\/17068","article-title":"Female development in mammals is regulated by Wnt-4 signaling","volume":"397","year":"1999","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224022137_R20","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0925-4773(98)00112-9","article-title":"Differential expression patterns of Wnt genes in the murine female reproductive tract during development and the estrous cycle","volume":"76","year":"1998","journal-title":"Mech Dev"},{"key":"key\n\t\t\t\t20170224022137_R21","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/onc.2008.363","article-title":"Beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus","volume":"28","year":"2009","journal-title":"Oncogene"},{"key":"key\n\t\t\t\t20170224022137_R22","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1242\/dev.01090","article-title":"Wnt5a is required for proper epithelial-mesenchymal interactions in the uterus","volume":"131","year":"2004","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224022137_R23","doi-asserted-by":"crossref","first-page":"3201","DOI":"10.1242\/dev.125.16.3201","article-title":"Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract","volume":"125","year":"1998","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224022137_R24","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1038\/27221","article-title":"Sexually dimorphic development of the mammalian reproductive tract requires Wnt-7a","volume":"395","year":"1998","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224022137_R25","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1242\/dev.120.2.335","article-title":"Msx1 (Hox-7.1) in the adult mouse uterus: cellular interactions underlying regulation of expression","volume":"120","year":"1994","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224022137_R26","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1210\/me.2003-0403","article-title":"Uterine Msx-1 and Wnt4 signaling becomes aberrant in mice with the loss of leukemia inhibitory factor or Hoxa-10: evidence for a novel cytokine-homeobox-Wnt signaling in implantation","volume":"18","year":"2004","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224022137_R27","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/3027","article-title":"Fetal exposure to DES results in deregulation of Wnt7a during uterine morphogenesis","volume":"20","year":"1998","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170224022137_R28","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/S0960-9822(99)80310-8","article-title":"Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner","volume":"9","year":"1999","journal-title":"Curr Biol"},{"key":"key\n\t\t\t\t20170224022137_R29","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0168-9525(00)02028-X","article-title":"The Wnt\/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape","volume":"16","year":"2000","journal-title":"Trends Genet"},{"key":"key\n\t\t\t\t20170224022137_R30","doi-asserted-by":"crossref","first-page":"37024","DOI":"10.1074\/jbc.M300191200","article-title":"Functional characterization of WNT7A signaling in PC12 cells: interaction with a FZD5:LRP6 receptor complex and modulation by Dickkopf proteins","volume":"278","year":"2003","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224022137_R31","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1006\/bbrc.2001.6076","article-title":"WNT2B2 mRNA, up-regulated in primary gastric cancer, is a positive regulator of the WNT-beta-catenin-TCF signaling pathway","volume":"289","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"key":"key\n\t\t\t\t20170224022137_R32","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.ydbio.2005.09.045","article-title":"Conditional deletion of beta-catenin in the mesenchyme of the developing mouse uterus results in a switch to adipogenesis in the myometrium","volume":"288","year":"2005","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224022137_R33","doi-asserted-by":"crossref","first-page":"3035","DOI":"10.1210\/me.2004-0259","article-title":"Canonical Wnt signaling is critical to estrogen-mediated uterine growth","volume":"18","year":"2004","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224022137_R34","doi-asserted-by":"crossref","first-page":"8579","DOI":"10.1073\/pnas.0500612102","article-title":"Uterine Wnt\/beta-catenin signaling is required for implantation","volume":"102","year":"2005","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224022137_R35","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/gene.20098","article-title":"Cre-mediated recombination in cell lineages that express the progesterone receptor","volume":"41","year":"2005","journal-title":"Genesis"},{"key":"key\n\t\t\t\t20170224022137_R36","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1038\/75973","article-title":"High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP","volume":"25","year":"2000","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170224022137_R37","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.semcdb.2007.12.001","article-title":"In vivo analysis of progesterone receptor action in the uterus during embryo implantation","volume":"19","year":"2008","journal-title":"Semin Cell Dev Biol"},{"key":"key\n\t\t\t\t20170224022137_R38","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1006\/dbio.2001.0458","article-title":"Epithelial-stromal tissue interaction in paramesonephric (mullerian) epithelial differentiation","volume":"240","year":"2001","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224022137_R39","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1095\/biolreprod.103.026534","article-title":"Wnt7a is a suppressor of cell death in the female reproductive tract and is required for postnatal and estrogen-mediated growth","volume":"71","year":"2004","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R40","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1387\/ijdb.082680jm","article-title":"The developing female genital tract: from genetics to epigenetics","volume":"53","year":"2009","journal-title":"Int J Dev Biol"},{"key":"key\n\t\t\t\t20170224022137_R41","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1095\/biolreprod.110.088161","article-title":"WNTs in the neonatal mouse uterus: potential regulation of endometrial gland development","volume":"84","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R42","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.modgep.2004.08.006","article-title":"Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues","volume":"5","year":"2004","journal-title":"Gene Expr Patterns"},{"key":"key\n\t\t\t\t20170224022137_R43","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/j.gde.2010.06.005","article-title":"The FoxA factors in organogenesis and differentiation","volume":"20","year":"2010","journal-title":"Curr Opin Genet Dev"},{"key":"key\n\t\t\t\t20170224022137_R44","doi-asserted-by":"crossref","first-page":"13809","DOI":"10.1074\/jbc.M414122200","article-title":"Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis","volume":"280","year":"2005","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224022137_R45","doi-asserted-by":"crossref","first-page":"e511.","DOI":"10.1186\/1471-2164-9-511","article-title":"Microarray analysis of Foxa2 mutant mouse embryos reveals novel gene expression and inductive roles for the gastrula organizer and its derivatives","volume":"9","year":"2008","journal-title":"BMC Genomics"},{"key":"key\n\t\t\t\t20170224022137_R46","doi-asserted-by":"crossref","first-page":"40231","DOI":"10.1074\/jbc.M305892200","article-title":"Beta-catenin is required for specification of proximal\/distal cell fate during lung morphogenesis","volume":"278","year":"2003","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224022137_R47","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/pros.20877","article-title":"Activation of beta-catenin in mouse prostate causes HGPIN and continuous prostate growth after castration","volume":"69","year":"2009","journal-title":"Prostate"},{"key":"key\n\t\t\t\t20170224022137_R48","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1242\/dev.034066","article-title":"Noncanonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2","volume":"136","year":"2009","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224022137_R49","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1095\/biolreprod.108.075416","article-title":"Wnt genes in the mouse uterus: potential regulation of implantation","volume":"80","year":"2009","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R50","doi-asserted-by":"crossref","first-page":"e8.","DOI":"10.1186\/1471-213X-2-8","article-title":"A transcriptional response to Wnt protein in human embryonic carcinoma cells","volume":"2","year":"2002","journal-title":"BMC Dev Biol"},{"key":"key\n\t\t\t\t20170224022137_R51","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/ng0494-348","article-title":"Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development","volume":"6","year":"1994","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170224022137_R52","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1210\/me.2003-0222","article-title":"Hoxa11 regulates stromal cell death and proliferation during neonatal uterine development","volume":"18","year":"2004","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224022137_R53","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1095\/biolreprod56.5.1097","article-title":"Abnormal uterine stromal and glandular function associated with maternal reproductive defects in Hoxa-11 null mice","volume":"56","year":"1997","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224022137_R54","doi-asserted-by":"crossref","first-page":"2687","DOI":"10.1242\/dev.122.9.2687","article-title":"Mechanisms of reduced fertility in Hoxa-10 mutant mice: uterine homeosis and loss of maternal Hoxa-10 expression","volume":"122","year":"1996","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224022137_R55","doi-asserted-by":"crossref","first-page":"S852","DOI":"10.2741\/1148","article-title":"Progesterone receptor-regulated gene networks in implantation","volume":"8","year":"2003","journal-title":"Front Biosci"},{"key":"key\n\t\t\t\t20170224022137_R56","doi-asserted-by":"crossref","first-page":"2954","DOI":"10.1210\/jcem.87.6.8563","article-title":"Uterine glands provide histiotrophic nutrition for the human fetus during the first trimester of pregnancy","volume":"87","year":"2002","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224022137_R57","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1006\/dbio.2000.9767","article-title":"Embryo implantation","volume":"223","year":"2000","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224022137_R58","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.tem.2007.06.002","article-title":"Mouse models of implantation","volume":"18","year":"2007","journal-title":"Trends Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224022137_R59","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/359076a0","article-title":"Blastocyst implantation depends on maternal expression of leukemia inhibitory factor","volume":"359","year":"1992","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224022137_R60","doi-asserted-by":"crossref","first-page":"11408","DOI":"10.1073\/pnas.88.24.11408","article-title":"Uterine expression of leukemia inhibitory factor coincides with the onset of blastocyst implantation","volume":"88","year":"1991","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224022137_R61","doi-asserted-by":"crossref","first-page":"4365","DOI":"10.1210\/endo.141.12.7855","article-title":"Leukemia inhibitory factor can substitute for nidatory estrogen and is essential to inducing a receptive uterus for implantation but is not essential for subsequent embryogenesis","volume":"141","year":"2000","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224022137_R62","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1210\/mend.14.8.0498","article-title":"Dysregulation of EGF family of growth factors and COX-2 in the uterus during the preattachment and attachment reactions of the blastocyst with the luminal epithelium correlates with implantation failure in LIF-deficient mice","volume":"14","year":"2000","journal-title":"Mol Endocrinol"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","deposited":{"date-parts":[[2021,11,21]],"date-time":"2021-11-21T23:44:16Z","timestamp":1637538256000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.111.091769"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8,1]]},"references-count":62,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011,8,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.111.091769","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,8,1]]}}}