{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:45:57Z","timestamp":1790178357253,"version":"4.1.0"},"reference-count":83,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,8,1]]},"DOI":"10.1095\/biolreprod.111.097527","type":"journal-article","created":{"date-parts":[[2012,5,31]],"date-time":"2012-05-31T06:05:45Z","timestamp":1338444345000},"source":"Crossref","is-referenced-by-count":12,"title":["Overexpression of Follistatin in the Mouse Epididymis Disrupts Fluid Resorption and Sperm Transit in Testicular Excurrent Ducts1"],"prefix":"10.1093","volume":"87","author":[{"given":"Darcie D.","family":"Seachrist","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emhonta","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christianne","family":"Magee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colin M.","family":"Clay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James K.","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.N. Rao","family":"Veeramachaneni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth A.","family":"Keri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224020403_R01","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/321779a0","article-title":"Pituitary FSH is released by a heterodimer of the [beta]-subunits from the two forms of inhibin","volume":"321","year":"1986","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224020403_R02","doi-asserted-by":"crossref","first-page":"8282","DOI":"10.1073\/pnas.84.23.8282","article-title":"Isolation and partial characterization of follistatin: a single-chain Mr 35,000 monomeric protein that inhibits the release of follicle-stimulating hormone","volume":"84","year":"1987","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224020403_R03","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1177\/153537020222700905","article-title":"Activins, inhibins, and follistatins: from endocrinology to signaling. A paradigm for the new millennium","volume":"227","year":"2002","journal-title":"Exp Biol Med"},{"key":"key\n\t\t\t\t20170224020403_R04","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s004670050653","article-title":"Collecting duct morphogenesis","volume":"13","year":"1999","journal-title":"Pediatr Nephrol"},{"key":"key\n\t\t\t\t20170224020403_R05","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1006\/dbio.2001.0399","article-title":"Activins as regulators of branching morphogenesis","volume":"238","year":"2001","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R06","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/0925-4773(94)00342-K","article-title":"Activin disrupts epithelial branching morphogenesis in developing glandular organs of the mouse","volume":"50","year":"1995","journal-title":"Mech Dev"},{"key":"key\n\t\t\t\t20170224020403_R07","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/dbio.2001.0364","article-title":"Regulation of prostate branching morphogenesis by activin a and follistatin","volume":"237","year":"2001","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R08","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.devcel.2005.09.008","article-title":"The structure of the follistatin: activin complex reveals antagonism of both type i and type ii receptor binding","volume":"9","year":"2005","journal-title":"Dev Cell"},{"key":"key\n\t\t\t\t20170224020403_R09","doi-asserted-by":"crossref","first-page":"9337","DOI":"10.1073\/pnas.95.16.9337","article-title":"Direct binding of follistatin to a complex of bone-morphogenetic protein and its receptor inhibits ventral and epidermal cell fates in early Xenopus embryo","volume":"95","year":"1998","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224020403_R10","doi-asserted-by":"crossref","first-page":"3586","DOI":"10.1210\/en.2006-0089","article-title":"Biological activity of follistatin isoforms and follistatin-like-3 is dependent on differential cell surface binding and specificity for activin, myostatin, and bone morphogenetic proteins","volume":"147","year":"2006","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R11","doi-asserted-by":"crossref","first-page":"4589","DOI":"10.1210\/en.2008-0259","article-title":"Differential Antagonism of activin, myostatin and growth and differentiation factor 11 by wild-type and mutant follistatin","volume":"149","year":"2008","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R12","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1006\/bbrc.2001.6103","article-title":"Follistatin inhibits the function of the oocyte-derived factor BMP-15","volume":"289","year":"2001","journal-title":"Biochem Biophys Res Comm"},{"key":"key\n\t\t\t\t20170224020403_R13","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1471-2202-2-12","article-title":"Bone morphogenetic protein-5 (BMP-5) promotes dendritic growth in cultured sympathetic neurons","volume":"2","year":"2001","journal-title":"BMC Neurosci"},{"key":"key\n\t\t\t\t20170224020403_R14","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/S0898-6568(00)00099-1","article-title":"Difference between follistatin isoforms in the inhibition of activin signalling: activin neutralizing activity of follistatin isoforms is dependent on their affinity for activin","volume":"12","year":"2000","journal-title":"Cell Signal"},{"key":"key\n\t\t\t\t20170224020403_R15","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1530\/rep.1.00090","article-title":"Bone morphogenetic protein (BMP) ligands and receptors in bovine ovarian follicle cells: actions of BMP-4, -6 and -7 on granulosa cells and differential modulation of Smad-1 phosphorylation by follistatin","volume":"127","year":"2004","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224020403_R16","first-page":"341","article-title":"Characterization of follistatin isoforms in early Xenopus embryogenesis","volume":"44","year":"2000","journal-title":"Int J Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R17","doi-asserted-by":"crossref","first-page":"15579","DOI":"10.1016\/S0021-9258(18)82296-7","article-title":"Molecular heterogeneity of follistatin, an activin-binding protein. Higher affinity of the carboxyl-terminal truncated forms for heparan sulfate proteoglycans on the ovarian granulosa cell","volume":"268","year":"1993","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224020403_R18","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/374356a0","article-title":"Different phenotypes for mice deficient in either activins or activin receptor type II","volume":"374","year":"1995","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224020403_R19","doi-asserted-by":"crossref","first-page":"1812","DOI":"10.1101\/gad.11.14.1812","article-title":"The signaling pathway mediated by the type IIB activin receptor controls axial patterning and lateral asymmetry in the mouse","volume":"11","year":"1997","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20170224020403_R20","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1101\/gad.12.6.844","article-title":"van den Eijnden-van Raaij J, Donahoe PK, Li E. The type I activin receptor ActRIB is required for egg cylinder organization and gastrulation in the mouse","volume":"12","year":"1998","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20170224020403_R21","doi-asserted-by":"crossref","first-page":"2551","DOI":"10.1242\/dev.126.11.2551","article-title":"van den Eijnden-van Raaij J, Donahoe PK, Li E. The type I serine\/threonine kinase receptor ActRIA (ALK2) is required for gastrulation of the mouse embryo","volume":"126","year":"1999","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224020403_R22","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1038\/78161","article-title":"Insertion of Inhbb into the Inhba locus rescues the Inhba-null phenotype and reveals new activin functions","volume":"25","year":"2000","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170224020403_R23","doi-asserted-by":"crossref","first-page":"10526","DOI":"10.1073\/pnas.1000318107","article-title":"a product of fetal Leydig cells, is a unique paracrine regulator of Sertoli cell proliferation and fetal testis cord expansion","volume":"107","year":"2010","journal-title":"Proc Natl Acad Sci"},{"key":"key\n\t\t\t\t20170224020403_R24","doi-asserted-by":"crossref","first-page":"184","DOI":"10.2353\/ajpath.2009.080296","article-title":"Activin C antagonizes activin A in vitro and overexpression leads to pathologies in vivo","volume":"174","year":"2009","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t20170224020403_R25","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1210\/mend.12.1.0053","article-title":"Overexpression of mouse follistatin causes reproductive defects in transgenic mice","volume":"12","year":"1998","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224020403_R26","doi-asserted-by":"crossref","first-page":"979","DOI":"10.1210\/me.2003-0364","article-title":"Overexpression of follistatin-like 3 in gonads causes defects in gonadal development and function in transgenic mice","volume":"18","year":"2004","journal-title":"Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224020403_R27","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1210\/endo-126-2-1156","article-title":"Oxytocin in the ovine ductuli efferentes and caput epididymidis: immunolocalization and endocytosis from the luminal fluid","volume":"126","year":"1990","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R28","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/j.1939-4640.1991.tb01602.x","article-title":"Endocytosis of androgen-binding protein, clusterin, and transferrin in the efferent ducts and epididymis of the ram","volume":"12","year":"1991","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224020403_R29","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1002\/j.1939-4640.1990.tb01594.x","article-title":"Proteins in luminal fluid of the ram excurrent ducts: changes in composition and evidence for differential endocytosis","volume":"11","year":"1990","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224020403_R30","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1071\/RD9930361","article-title":"The epididymis and sperm maturation: a perspective","volume":"5","year":"1993","journal-title":"Reprod Fertil Dev"},{"key":"key\n\t\t\t\t20170224020403_R31","first-page":"999","article-title":"Efferent ducts, epididymis, and vas deferens: structure, functions, and their regulation","volume-title":"Physiology of Reproduction, vol. 1, 3rd ed","year":"1988"},{"key":"key\n\t\t\t\t20170224020403_R32","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/978-1-4615-0679-9_4","article-title":"The efferent ductules: structure and function","volume-title":"The Epididymis: From Molecules to Clinical Practice: A Comprehensive Survey of the Efferent Ducts, the Epididymis and the Vas Deferens","year":"2002"},{"key":"key\n\t\t\t\t20170224020403_R33","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.fertnstert.2004.05.104","article-title":"Tissue immunoexpression and messenger ribonucleic acid localization of inhibin\/activin subunit in human epididymis","volume":"83","year":"2005","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224020403_R34","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/molehr\/3.11.945","article-title":"Localization of plasminogen activator and inhibitor, LH and androgen receptors and inhibin subunits in monkey epididymis","volume":"3","year":"1997","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224020403_R35","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1530\/eje.0.1420537","article-title":"Comparative analysis of follistatin-, activin beta A- and activin beta B-mRNA steady-state levels in diverse porcine tissues by multiplex S1 nuclease analysis","volume":"142","year":"2000","journal-title":"Eur J Endocrinol"},{"key":"key\n\t\t\t\t20170224020403_R36","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1016\/S0012-1606(03)00100-3","article-title":"Regulation of metanephric kidney development by growth\/differentiation factor 11","volume":"257","year":"2003","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R37","doi-asserted-by":"crossref","first-page":"11322","DOI":"10.1073\/pnas.0703445104","article-title":"Essential roles of inhibin beta A in mouse epididymal coiling","volume":"104","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224020403_R38","doi-asserted-by":"crossref","first-page":"4323","DOI":"10.1093\/nar\/25.21.4323","article-title":"Cre-mediated gene deletion in the mammary gland","volume":"25","year":"1997","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t20170224020403_R39","volume-title":"The Mouse: Its Reproduction and Development","year":"1990"},{"key":"key\n\t\t\t\t20170224020403_R40","doi-asserted-by":"crossref","first-page":"2045","DOI":"10.1242\/dev.043299","article-title":"FOXA1 is an essential determinant of ERalpha expression and mammary ductal morphogenesis","volume":"137","year":"2010","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224020403_R41","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1262\/jrd.18023","article-title":"The relationship between sperm morphology and in vitro fertilization ability in mice","volume":"52","year":"2006","journal-title":"J Reprod Dev"},{"key":"key\n\t\t\t\t20170224020403_R42","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1210\/endo-122-3-787","article-title":"Evidence from Sertoli cell-depleted rats indicates that spermatid number in adults depends on numbers of Sertoli cells produced during perinatal development","volume":"122","year":"1988","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R43","doi-asserted-by":"crossref","first-page":"5438","DOI":"10.1210\/endo.136.12.7588293","article-title":"Activin stimulates Sertoli cell proliferation in a defined period of rat testis development","volume":"136","year":"1995","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R44","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1210\/en.2002-220595","article-title":"Proliferative phase Sertoli cells display a developmentally regulated response to activin in vitro","volume":"144","year":"2003","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R45","doi-asserted-by":"crossref","first-page":"2916","DOI":"10.1210\/endo.142.7.8230","article-title":"Rajendra Kumar T, Matzuk MM, de Kretser DM. Analysis of the testicular phenotype of the follicle-stimulating hormone {beta}-subunit knockout and the activin type II receptor knockout mice by stereological analysis","volume":"142","year":"2001","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R46","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1038\/374356a0","article-title":"Different phenotypes for mice deficient in either activins or activin receptor type II","volume":"374","year":"1995","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224020403_R47","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/ng0297-201","article-title":"Follicle stimulating hormone is required for ovarian follicle maturation but not male fertility","volume":"15","year":"1997","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170224020403_R48","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1023\/A:1013063514007","article-title":"Spatial and temporal expression of the Cre gene under the control of the MMTV-LTR in different lines of transgenic mice","volume":"10","year":"2001","journal-title":"Transgenic Res"},{"key":"key\n\t\t\t\t20170224020403_R49","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1002\/j.1939-4640.2000.tb03282.x","article-title":"Morphologic changes in efferent ductules and epididymis in estrogen receptor-alpha knockout mice","volume":"21","year":"2000","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224020403_R50","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1095\/biolreprod63.6.1873","article-title":"Estrogen receptor alpha has a functional role in the mouse rete testis and efferent ductules","volume":"63","year":"2000","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R51","doi-asserted-by":"crossref","first-page":"11162","DOI":"10.1073\/pnas.90.23.11162","article-title":"Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene","volume":"90","year":"1993","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224020403_R52","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1677\/JOE-10-0290","article-title":"Ex3alphaERKO male infertility phenotype recapitulates the alpha ERKO male phenotype","volume":"207","year":"2010","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224020403_R53","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1242\/dev.127.19.4277","article-title":"Effect of single and compound knockouts of estrogen receptors alpha (ERalpha) and beta (ERbeta) on mouse reproductive phenotypes","volume":"127","year":"2000","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224020403_R54","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1210\/en.2008-0044","article-title":"Defects of prostate development and reproductive system in the estrogen receptor-{alpha} null male mice","volume":"150","year":"2009","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224020403_R55","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1095\/biolreprod.110.087353","article-title":"Estrogen, efferent ductules, and the epididymis","volume":"84","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R56","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/ar.1071","article-title":"Morphological analysis of endocytosis in efferent ductules of estrogen receptor-\u03b1 knockout male mouse","volume":"263","year":"2001","journal-title":"Anat Rec"},{"key":"key\n\t\t\t\t20170224020403_R57","doi-asserted-by":"crossref","first-page":"36755","DOI":"10.1074\/jbc.M705143200","article-title":"Activin regulates estrogen receptor gene expression in the mouse ovary","volume":"282","year":"2007","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224020403_R58","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1677\/JOE-08-0226","article-title":"Bone morphogenetic protein 6 (BMP6) and BMP7 inhibit estrogen-induced proliferation of breast cancer cells by suppressing p38 mitogen-activated protein kinase activation","volume":"199","year":"2008","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224020403_R59","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1095\/biolreprod.109.079053","article-title":"Regulation of gene expression by estrogen and testosterone in the proximal mouse reproductive tract","volume":"81","year":"2009","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R60","doi-asserted-by":"crossref","first-page":"14132","DOI":"10.1073\/pnas.241245898","article-title":"Estrogen action and male fertility: roles of the sodium\/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function","volume":"98","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224020403_R61","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1042\/BC20040078","article-title":"Aquaporin-1 and -9 are differentially regulated by oestrogen in the efferent ductule epithelium and initial segment of the epididymis","volume":"97","year":"2005","journal-title":"Biol Cell"},{"key":"key\n\t\t\t\t20170224020403_R62","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.ydbio.2008.10.015","article-title":"Inhibition and transcriptional silencing of a subtilisin-like proprotein convertase, PACE4\/SPC4, reduces the branching morphogenesis of and AQP5 expression in rat embryonic submandibular gland","volume":"325","year":"2009","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R63","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1111\/j.1365-2443.2006.01009.x","article-title":"Chromatin immunoprecipitation-mediated target identification proved aquaporin 5 is regulated directly by estrogen in the uterus","volume":"11","year":"2006","journal-title":"Genes Cells"},{"key":"key\n\t\t\t\t20170224020403_R64","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1369\/jhc.2008.951947","article-title":"Membrane domain specificity in the spatial distribution of aquaporins 5, 7, 9, and 11 in efferent ducts and epididymis of rats","volume":"56","year":"2008","journal-title":"J Histochem Cytochem"},{"key":"key\n\t\t\t\t20170224020403_R65","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1530\/rep.1.00136","article-title":"Differential hormonal regulation of estrogen receptors ER{alpha} and ER{beta} and androgen receptor expression in rat efferent ductules","volume":"128","year":"2004","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224020403_R66","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.devcel.2004.09.012","article-title":"Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation","volume":"7","year":"2004","journal-title":"Dev Cell"},{"key":"key\n\t\t\t\t20170224020403_R67","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1038\/387083a0","article-title":"Regulation of skeletal muscle mass in mice by a new TGF-p superfamily member","volume":"387","year":"1997","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224020403_R68","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1242\/dev.125.6.1103","article-title":"Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis","volume":"125","year":"1998","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224020403_R69","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1006\/dbio.2001.0448","article-title":"Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis","volume":"240","year":"2001","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R70","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1002\/(SICI)1097-0177(199703)208:3<349::AID-AJA6>3.0.CO;2-I","article-title":"Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos","volume":"208","year":"1997","journal-title":"Dev Dyn"},{"key":"key\n\t\t\t\t20170224020403_R71","doi-asserted-by":"crossref","first-page":"2808","DOI":"10.1101\/gad.9.22.2808","article-title":"BMP-7 is an inducer of nephrogenesis, and is also required for eye development and skeletal patterning","volume":"9","year":"1995","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20170224020403_R72","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1210\/er.2003-0007","article-title":"The bone morphogenetic protein system in mammalian reproduction","volume":"25","year":"2004","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224020403_R73","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ydbio.2004.08.034","article-title":"Developmental expression and function of Bmp4 in spermatogenesis and in maintaining epididymal integrity","volume":"276","year":"2004","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224020403_R74","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1161\/CIRCULATIONAHA.106.683227","article-title":"Bone morphogenic protein antagonists are coexpressed with bone morphogenic protein 4 in endothelial cells exposed to unstable flow in vitro in mouse aortas and in human coronary arteries: role of bone morphogenic protein antagonists in inflammation and atherosclerosis","volume":"116","year":"2007","journal-title":"Circulation"},{"key":"key\n\t\t\t\t20170224020403_R75","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0925-4773(97)00673-4","article-title":"The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4","volume":"63","year":"1997","journal-title":"Mech Dev"},{"key":"key\n\t\t\t\t20170224020403_R76","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/j.1939-4640.1997.tb01922.x","article-title":"Effects of heat stress on mouse testicular cells and sperm chromatin structure","volume":"18","year":"1997","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224020403_R77","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1095\/biolreprod32.1.120","article-title":"Cauda epididymal sperm motility: a comparison among five species","volume":"32","year":"1985","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R78","first-page":"E143","article-title":"Direct evaluation of acidification by rat testis and epididymis: role of carbonic anhydrase","volume":"258","year":"1990","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20170224020403_R79","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1095\/biolreprod33.3.588","article-title":"Effects of pH, lactate, and viscoelastic drag on sperm motility: a species comparison","volume":"33","year":"1985","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R80","doi-asserted-by":"crossref","first-page":"4131","DOI":"10.1038\/sj.emboj.7601272","article-title":"Epididymal expression of the forkhead transcription factor Foxi1 is required for male fertility","volume":"25","year":"2006","journal-title":"EMBO J"},{"key":"key\n\t\t\t\t20170224020403_R81","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1095\/biolreprod.109.079889","article-title":"Absence of estrogen receptor alpha leads to physiological alterations in the mouse epididymis and consequent defects in sperm function","volume":"82","year":"2010","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R82","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1095\/biolreprod.109.080366","article-title":"Epididymal hypo-osmolality induces abnormal sperm morphology and function in the estrogen receptor alpha knockout mouse","volume":"82","year":"2010","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224020403_R83","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.beem.2010.08.008","article-title":"The struggle for male hormonal contraception","volume":"25","year":"2011","journal-title":"Best Pract Res Clin Endocrinol Metab"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/87\/2\/41","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T21:46:53Z","timestamp":1713995213000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.111.097527"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,8,1]]},"references-count":83,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,8,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.111.097527","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,8,1]]}}}