{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T20:22:03Z","timestamp":1767990123218,"version":"3.49.0"},"reference-count":66,"publisher":"Oxford University Press (OUP)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,12,1]]},"DOI":"10.1095\/biolreprod.114.122168","type":"journal-article","created":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T08:51:46Z","timestamp":1415350306000},"source":"Crossref","is-referenced-by-count":20,"title":["Regulation of the Pannexin-1 Promoter in the Rat Epididymis1"],"prefix":"10.1093","volume":"91","author":[{"given":"Julie","family":"Dufresne","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel G.","family":"Cyr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224010428_CIT0001","doi-asserted-by":"crossref","first-page":"325","DOI":"10.4161\/spmg.1.4.18948","article-title":"Connexins and pannexins: Coordinating cellular communication in the testis and epididymis","volume":"1","year":"2011","journal-title":"Spermatogenesis"},{"key":"key\n\t\t\t\t20170224010428_CIT0002","first-page":"58","article-title":"The pannexins: past and present","volume":"5","year":"2014","journal-title":"Front Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0003","doi-asserted-by":"crossref","first-page":"193","DOI":"10.4161\/chan.5.3.15765","article-title":"Pannexin channels are not gap junction hemichannels","volume":"5","year":"2011","journal-title":"Channels (Austin)"},{"key":"key\n\t\t\t\t20170224010428_CIT0004","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bbamem.2012.01.017","article-title":"The biochemistry and function of pannexin channels","volume":"1828","year":"2013","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170224010428_CIT0005","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.pbiomolbio.2007.03.006","article-title":"Gap junctional proteins of animals: the innexin\/pannexin superfamily","volume":"94","year":"2007","journal-title":"Prog Biophys Mol Biol"},{"key":"key\n\t\t\t\t20170224010428_CIT0006","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1007\/s00018-007-7200-1","article-title":"Pannexins and gap junction protein diversity","volume":"65","year":"2008","journal-title":"Cell Mol Life Sci"},{"key":"key\n\t\t\t\t20170224010428_CIT0007","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1002\/bies.200800236","article-title":"Pannexins, distant relatives of the connexin family with specific cellular functions?","volume":"31","year":"2009","journal-title":"Bioessays"},{"key":"key\n\t\t\t\t20170224010428_CIT0008","doi-asserted-by":"crossref","first-page":"81","DOI":"10.4161\/chan.2.2.6003","article-title":"Connexin and pannexin hemichannels of neurons and astrocytes","volume":"2","year":"2008","journal-title":"Channels (Austin)"},{"key":"key\n\t\t\t\t20170224010428_CIT0009","doi-asserted-by":"crossref","first-page":"13644","DOI":"10.1073\/pnas.2233464100","article-title":"Pannexins, a family of gap junction proteins expressed in brain","volume":"100","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224010428_CIT0010","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.febslet.2014.01.028","article-title":"Regulation of pannexin channels by post-translational modifications","volume":"588","year":"2014","journal-title":"FEBS Lett"},{"key":"key\n\t\t\t\t20170224010428_CIT0011","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1042\/BJ20140447","article-title":"Pannexin channels and their links to human disease","volume":"461","year":"2014","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224010428_CIT0012","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.1091\/mbc.E09-01-0067","article-title":"Glycosylation regulates pannexin intermixing and cellular localization","volume":"20","year":"2009","journal-title":"Mol Biol Cell"},{"key":"key\n\t\t\t\t20170224010428_CIT0013","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1080\/15419060802014115","article-title":"Diverse subcellular distribution profiles of pannexin 1 and pannexin 3","volume":"15","year":"2008","journal-title":"Cell Commun Adhes"},{"key":"key\n\t\t\t\t20170224010428_CIT0014","doi-asserted-by":"crossref","first-page":"3772","DOI":"10.1242\/jcs.009514","article-title":"Pannexin 1 and pannexin 3 are glycoproteins that exhibit many distinct characteristics from the connexin family of gap junction proteins","volume":"120","year":"2007","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170224010428_CIT0015","doi-asserted-by":"crossref","first-page":"39602","DOI":"10.1074\/jbc.M112.397976","article-title":"S-nitrosylation inhibits pannexin 1 channel function","volume":"287","year":"2012","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224010428_CIT0016","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1038\/nature09413","article-title":"Pannexin 1 channels mediate \u2018find-me' signal release and membrane permeability during apoptosis","volume":"467","year":"2010","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224010428_CIT0017","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1002\/mrd.21280","article-title":"Characterization of pannexin1 and pannexin3 and their regulation by androgens in the male reproductive tract of the adult rat","volume":"78","year":"2011","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224010428_CIT0018","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.febslet.2004.07.009","article-title":"Pannexin membrane channels are mechanosensitive conduits for ATP","volume":"572","year":"2004","journal-title":"FEBS Lett"},{"key":"key\n\t\t\t\t20170224010428_CIT0019","doi-asserted-by":"crossref","first-page":"C752","DOI":"10.1152\/ajpcell.00228.2008","article-title":"P2X7 receptor-pannexin1 complex: pharmacology and signaling","volume":"295","year":"2008","journal-title":"Am J Physiol Cell Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0020","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.febslet.2005.12.004","article-title":"Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium","volume":"580","year":"2006","journal-title":"FEBS Lett"},{"key":"key\n\t\t\t\t20170224010428_CIT0021","doi-asserted-by":"crossref","first-page":"C817","DOI":"10.1152\/ajpcell.00460.2009","article-title":"Role of purinergic signaling pathways in V-ATPase recruitment to apical membrane of acidifying epididymal clear cells","volume":"298","year":"2010","journal-title":"Am J Physiol Cell Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0022","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.1113\/jphysiol.2012.230581","article-title":"ATP secretion in the male reproductive tract: essential role of CFTR","volume":"590","year":"2012","journal-title":"J Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0023","doi-asserted-by":"crossref","first-page":"576","DOI":"10.2164\/jandrol.111.012971","article-title":"Establishment of cell-cell cross talk in the epididymis: control of luminal acidification","volume":"32","year":"2011","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224010428_CIT0024","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S1472-6483(10)60801-2","article-title":"Molecular pathology of the CFTR locus in male infertility","volume":"10","year":"2005","journal-title":"Reprod Biomed Online"},{"key":"key\n\t\t\t\t20170224010428_CIT0025","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1365-2605.2004.00485.x","article-title":"CFTR mutations and polymorphisms in male infertility","volume":"27","year":"2004","journal-title":"Int J Androl"},{"key":"key\n\t\t\t\t20170224010428_CIT0026","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1002\/(SICI)1098-2795(200002)55:2<125::AID-MRD1>3.0.CO;2-Q","article-title":"Morphological changes in the vas deferens and expression of the cystic fibrosis transmembrane conductance regulator (CFTR) in control, deltaF508 and knock-out CFTR mice during postnatal life","volume":"55","year":"2000","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224010428_CIT0027","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1093\/molehr\/4.2.107","article-title":"CFTR gene and male fertility","volume":"4","year":"1998","journal-title":"Mol Hum Reprod"},{"key":"key\n\t\t\t\t20170224010428_CIT0028","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1172\/JCI43052","article-title":"Disease phenotype of a ferret CFTR-knockout model of cystic fibrosis","volume":"120","year":"2010","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224010428_CIT0029","doi-asserted-by":"crossref","first-page":"4209","DOI":"10.1113\/jphysiol.2012.230581","article-title":"ATP secretion in the male reproductive tract: essential role of CFTR","volume":"590","year":"2012","journal-title":"J Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0030","first-page":"246","article-title":"Toward a multiscale description of microvascular flow regulation: O(2)-dependent release of ATP from human erythrocytes and the distribution of ATP in capillary networks","volume":"3","year":"2012","journal-title":"Front Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0031","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1189\/jlb.0512249","article-title":"Pannexin1 hemichannels are critical for HIV infection of human primary CD4+ T lymphocytes","volume":"94","year":"2013","journal-title":"J Leukoc Biol"},{"key":"key\n\t\t\t\t20170224010428_CIT0032","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1084\/jem.20101805","article-title":"Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection","volume":"208","year":"2011","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170224010428_CIT0033","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1189\/jlb.0313148","article-title":"Editorial: Pannexin-1\u2014the hidden gatekeeper for HIV-1","volume":"94","year":"2013","journal-title":"J Leukoc Biol"},{"key":"key\n\t\t\t\t20170224010428_CIT0034","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1126\/science.1165209","article-title":"Activation of pannexin-1 hemichannels augments aberrant bursting in the hippocampus","volume":"322","year":"2008","journal-title":"Science"},{"key":"key\n\t\t\t\t20170224010428_CIT0035","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.tins.2009.11.007","article-title":"Non-junction functions of pannexin-1 channels","volume":"33","year":"2010","journal-title":"Trends Neurosci"},{"key":"key\n\t\t\t\t20170224010428_CIT0036","first-page":"172","article-title":"Roles of gap junctions, connexins, and pannexins in epilepsy","volume":"5","year":"2014","journal-title":"Front Physiol"},{"key":"key\n\t\t\t\t20170224010428_CIT0037","doi-asserted-by":"crossref","first-page":"7092","DOI":"10.1523\/JNEUROSCI.6062-08.2009","article-title":"Pannexin 1: the molecular substrate of astrocyte \u201chemichannels\u201d","volume":"29","year":"2009","journal-title":"J Neurosci"},{"key":"key\n\t\t\t\t20170224010428_CIT0038","doi-asserted-by":"crossref","first-page":"2911","DOI":"10.1002\/jbmr.509","article-title":"Pannexin 3 is a novel target for Runx2, expressed by osteoblasts and mature growth plate chondrocytes","volume":"26","year":"2011","journal-title":"J Bone Miner Res"},{"key":"key\n\t\t\t\t20170224010428_CIT0039","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.neuropharm.2013.02.019","article-title":"The bizarre pharmacology of the ATP release channel pannexin1","volume":"75","year":"2013","journal-title":"Neuropharmacology"},{"key":"key\n\t\t\t\t20170224010428_CIT0040","doi-asserted-by":"crossref","first-page":"4710","DOI":"10.1210\/en.2004-1634","article-title":"Characterization of a novel rat epididymal cell line to study epididymal function","volume":"146","year":"2005","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224010428_CIT0041","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1095\/biolreprod.106.057430","article-title":"Activation of an SP binding site is crucial for the expression of claudin 1 in rat epididymal principal cells","volume":"76","year":"2007","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224010428_CIT0042","doi-asserted-by":"crossref","first-page":"8292","DOI":"10.1128\/MCB.14.12.8292","article-title":"The Ikaros gene encodes a family of functionally diverse zinc finger DNA-binding proteins","volume":"14","year":"1994","journal-title":"Mol Cell Biol"},{"key":"key\n\t\t\t\t20170224010428_CIT0043","first-page":"287","article-title":"The emerging Pannexin 1 signalome: a new nexus revealed?","volume":"7","year":"2014","journal-title":"Front Cell Neurosci"},{"key":"key\n\t\t\t\t20170224010428_CIT0044","doi-asserted-by":"crossref","first-page":"18143","DOI":"10.1074\/jbc.M109.004804","article-title":"de Rivero Vaccari JP, Locovei S, Qiu F, Carlsson SK, Scemes E, Keane RW, Dahl G. The pannexin 1 channel activates the inflammasome in neurons and astrocytes","volume":"284","year":"2009","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224010428_CIT0045","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1016\/j.micinf.2012.05.010","article-title":"Pipoli da Fonseca J, Caillet M, Kroemer G, Perfettini JL. Multifaceted roles of purinergic receptors in viral infection","volume":"14","year":"2012","journal-title":"Microbes Infect"},{"key":"key\n\t\t\t\t20170224010428_CIT0046","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/aps.2012.95","article-title":"Ionotropic receptors and ion channels in ischemic neuronal death and dysfunction","volume":"34","year":"2013","journal-title":"Acta Pharmacol Sin"},{"key":"key\n\t\t\t\t20170224010428_CIT0047","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/ng1789","article-title":"Genome-wide analysis of mammalian promoter architecture and evolution","volume":"38","year":"2006","journal-title":"Nat Genet"},{"key":"key\n\t\t\t\t20170224010428_CIT0048","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0022-2836(87)90689-9","article-title":"CpG islands in vertebrate genomes","volume":"196","year":"1987","journal-title":"J Mol Biol"},{"key":"key\n\t\t\t\t20170224010428_CIT0049","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ceb.2008.03.003","article-title":"The RNA polymerase II core promoter\u2014the gateway to transcription","volume":"20","year":"2008","journal-title":"Curr Opin Cell Biol"},{"key":"key\n\t\t\t\t20170224010428_CIT0050","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.gene.2013.07.054","article-title":"Screening of transcription factors with transcriptional initiation activity","volume":"531","year":"2013","journal-title":"Gene"},{"key":"key\n\t\t\t\t20170224010428_CIT0051","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1101\/gad.1026202","article-title":"The RNA polymerase II core promoter: a key component in the regulation of gene expression","volume":"16","year":"2002","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20170224010428_CIT0052","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1002\/j.1939-4640.1997.tb01941.x","article-title":"Differential methylation in steroid 5 alpha-reductase isozyme genes in epididymis, testis, and liver of the adult rat","volume":"18","year":"1997","journal-title":"J Androl"},{"key":"key\n\t\t\t\t20170224010428_CIT0053","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1507\/endocrj.K06-009","article-title":"Neonatal exposure to diethylstilbestrol alters the expression of DNA methyltransferases and methylation of genomic DNA in the epididymis of mice","volume":"53","year":"2006","journal-title":"Endocr J"},{"key":"key\n\t\t\t\t20170224010428_CIT0054","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1267\/ahc.08025","article-title":"MeCP2 expression and promoter methylation of cyclin D1 gene are associated with cyclin D1 expression in developing rat epididymal duct","volume":"41","year":"2008","journal-title":"Acta Histochem Cytochem"},{"key":"key\n\t\t\t\t20170224010428_CIT0055","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1073\/pnas.89.1.38","article-title":"Molecular characterization of NSCL, a gene encoding a helix-loop-helix protein expressed in the developing nervous system","volume":"89","year":"1992","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224010428_CIT0056","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1242\/dev.127.2.425","article-title":"Regulation of neurogenesis by interactions between HEN1 and neuronal LMO proteins","volume":"127","year":"2000","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224010428_CIT0057","first-page":"1","article-title":"ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors","volume":"1826","year":"2012","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170224010428_CIT0058","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.mce.2005.12.045","article-title":"Identifying putative contraceptive targets by dissecting signal transduction networks in the epididymis using an in vivo electroporation (electrotransfer) approach","volume":"250","year":"2006","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224010428_CIT0059","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1101\/gad.6.3.481","article-title":"Molecular cloning and characterization of PEA3, a new member of the Ets oncogene family that is differentially expressed in mouse embryonic cells","volume":"6","year":"1992","journal-title":"Genes Dev"},{"key":"key\n\t\t\t\t20170224010428_CIT0060","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1210\/en.2003-0831","article-title":"Immortalization of epididymal epithelium in transgenic mice expressing simian virus 40 T antigen: characterization of cell lines and regulation of the polyoma enhancer activator 3","volume":"145","year":"2004","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224010428_CIT0061","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1095\/biolreprod57.1.186","article-title":"Identification, expression, and regulation of the transcriptional factor polyomavirus enhancer activator 3, and its putative role in regulating the expression of gamma-glutamyl transpeptidase mRNA-IV in the rat epididymis","volume":"57","year":"1997","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224010428_CIT0062","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1095\/biolreprod60.3.664","article-title":"Involvement of polyomavirus enhancer activator 3 in the regulation of expression of gamma-glutamyl transpeptidase messenger ribonucleic acid-IV in the rat epididymis","volume":"60","year":"1999","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224010428_CIT0063","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1002\/(SICI)1098-2795(199802)49:2<131::AID-MRD4>3.0.CO;2-Q","article-title":"The PEA3 protein of the Ets oncogene family is a putative transcriptional modulator of the mouse epididymis-specific glutathione peroxidase gene gpx5","volume":"49","year":"1998","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224010428_CIT0064","first-page":"492","volume-title":"Memories Are Made from These: from Messengers to Molecules","year":"2004"},{"key":"key\n\t\t\t\t20170224010428_CIT0065","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1242\/dev.040659","article-title":"G protein-coupled receptor 48 upregulates estrogen receptor alpha expression via cAMP\/PKA signaling in the male reproductive tract","volume":"137","year":"2010","journal-title":"Development"},{"key":"key\n\t\t\t\t20170224010428_CIT0066","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1530\/JOE-10-0223","article-title":"Androgens activate mitogen-activated protein kinase via epidermal growth factor receptor\/insulin-like growth factor 1 receptor in the mouse PC-1 cell line","volume":"209","year":"2011","journal-title":"J Endocrinol"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/91\/6\/143","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,4]],"date-time":"2024-06-04T21:00:18Z","timestamp":1717534818000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.114.122168"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12,1]]},"references-count":66,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2014,12,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.114.122168","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,12,1]]}}}