{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T05:44:14Z","timestamp":1790747054646,"version":"4.1.0"},"reference-count":116,"publisher":"Oxford University Press (OUP)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,4,1]]},"DOI":"10.1095\/biolreprod.115.134908","type":"journal-article","created":{"date-parts":[[2016,3,3]],"date-time":"2016-03-03T04:49:24Z","timestamp":1456980564000},"source":"Crossref","is-referenced-by-count":98,"title":["Biology of Preimplantation Conceptus at the Onset of Elongation in Dairy Cows1"],"prefix":"10.1093","volume":"94","author":[{"given":"Eduardo S.","family":"Ribeiro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leandro F.","family":"Greco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael S.","family":"Bisinotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1bio S.","family":"Lima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William W.","family":"Thatcher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 E.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224031620_CIT0001","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1071\/RD06102","article-title":"Pregnancy recognition and conceptus implantation in domestic ruminants: roles of progesterone, interferons and endogenous retroviruses","volume":"19","year":"2007","journal-title":"Reprod Fert Dev"},{"key":"key\n\t\t\t\t20170224031620_CIT0002","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/aja.1001590305","article-title":"An electron microscopic study of implantation in the cow","volume":"159","year":"1980","journal-title":"Am J Anat"},{"key":"key\n\t\t\t\t20170224031620_CIT0003","first-page":"513","article-title":"The effect of embryonic death rates in cattle on the efficacy of estrus synchronization programs","volume":"82","year":"2004","journal-title":"Anim Reprod Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0004","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1071\/RD09221","article-title":"Factors affecting fertilisation and early embryo quality in single- and superovulated dairy cattle","volume":"22","year":"2010","journal-title":"Reprod Fert Dev"},{"key":"key\n\t\t\t\t20170224031620_CIT0005","first-page":"370","article-title":"Economic aspects of applying reproductive technologies to dairy herds","volume":"9","year":"2012","journal-title":"Anim Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0006","first-page":"10","article-title":"Low doses of bovine somatotropin enhance conceptus development and fertility in lactating dairy cows","volume":"90","year":"2014","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0007","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1095\/biolreprod64.6.1608","article-title":"Endometrial glands are required for conceptus elongation and survival","volume":"64","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0008","first-page":"91","article-title":"Antiluteolytic effects of bovine trophoblast protein-1","volume":"37","year":"1989","journal-title":"J Reprod Fert"},{"key":"key\n\t\t\t\t20170224031620_CIT0009","doi-asserted-by":"crossref","first-page":"5681","DOI":"10.1073\/pnas.0811841106","article-title":"The endometrium responds differently to cloned versus fertilized embryos","volume":"106","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224031620_CIT0010","first-page":"5687","article-title":"Endometrium as an early sensor of in vitro embryo manipulation technologies","volume":"14","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224031620_CIT0011","first-page":"6","article-title":"Conceptus-endometrium crosstalk during maternal recognition of pregnancy in cattle","volume":"87","year":"2012","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0012","volume-title":"Nutrient Requirements of Dairy Cattle, 7th rev ed","author":"National Research Council","year":"2001"},{"key":"key\n\t\t\t\t20170224031620_CIT0013","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/0093-691X(88)90038-6","article-title":"The anatomy and physiology of preattachment bovine embryos","volume":"29","year":"1988","journal-title":"Theriogenology"},{"issue":"(7)","key":"key\n\t\t\t\t20170224031620_CIT0014","first-page":"research0034.1","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","year":"2002","journal-title":"Genome Biology"},{"key":"key\n\t\t\t\t20170224031620_CIT0015","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2-\u0394\u0394Ct method","volume":"25","year":"2001","journal-title":"Methods"},{"key":"key\n\t\t\t\t20170224031620_CIT0016","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1186\/1471-2105-7-85","article-title":"Statistical analysis of real-time PCR data","volume":"7","year":"2006","journal-title":"BMC Bioinformatics"},{"key":"key\n\t\t\t\t20170224031620_CIT0017","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1095\/biolreprod.111.094771","article-title":"Comparison of the effects of early pregnancy with human interferon alpha 2 (IFNA2) on gene expression in bovine endometrium","volume":"86","year":"2012","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0018","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1186\/1471-2105-11-395","article-title":"MZmine 2: modular framework for processing, visualizing, and analyzing mass spectrometry based molecular profile data","volume":"11","year":"2010","journal-title":"BMC Bioinformatics"},{"key":"key\n\t\t\t\t20170224031620_CIT0019","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.anireprosci.2008.02.014","article-title":"Oxygen tension and medium type actions on blastocyst development and interferon-tau secretion in cattle","volume":"111","year":"2009","journal-title":"Anim Reprod Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0020","doi-asserted-by":"crossref","first-page":"2695","DOI":"10.3168\/jds.S0022-0302(94)77212-X","article-title":"Principal descriptors of body condition score in Holstein cows","volume":"77","year":"1994","journal-title":"J Dairy Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0021","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1198\/016214504000000683","article-title":"A model-based background adjustment for oligonucleotide expression arrays","volume":"99","year":"2004","journal-title":"J Am Stat Assoc"},{"key":"key\n\t\t\t\t20170224031620_CIT0022","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/biostatistics\/kxj037","article-title":"Adjusting batch effects in microarray expression data using empirical Bayes methods","volume":"8","year":"2007","journal-title":"Biostatistics"},{"key":"key\n\t\t\t\t20170224031620_CIT0023","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1007\/0-387-29362-0_23","article-title":"Limma: linear models for microarray data","volume-title":"Bioinformatics and Computational Biology Solutions Using R and Bioconductor","year":"2005"},{"issue":"(1)","key":"key\n\t\t\t\t20170224031620_CIT0024","article-title":"Linear models and empirical Bayes methods for assessing differential expression in microarray experiments","volume":"3","year":"2004","journal-title":"Stat Applic Genet Mol Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0025","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate\u2013a practical and powerful approach to multiple testing","volume":"57","year":"1995","journal-title":"J R Stat Soc Series B Stat Methodol"},{"key":"key\n\t\t\t\t20170224031620_CIT0026","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/bioinformatics\/btt703","article-title":"Causal analysis approaches in Ingenuity Pathway Analysis","volume":"30","year":"2014","journal-title":"Bioinformatics"},{"key":"key\n\t\t\t\t20170224031620_CIT0027","doi-asserted-by":"crossref","first-page":"141","DOI":"10.2144\/000113999","article-title":"LASAGNA-Search: an integrated web tool for transcription factor binding site search and visualization","volume":"54","year":"2013","journal-title":"Biotechniques"},{"key":"key\n\t\t\t\t20170224031620_CIT0028","first-page":"1","article-title":"MetaboAnalyst 2.0\u2013a comprehensive server for metabolomic data analysis","volume":"40","year":"2012","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t20170224031620_CIT0029","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1101\/gad.501108","article-title":"Genome-wide profiling of PPAR\u03b3:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis","volume":"22","year":"2008","journal-title":"Gen Dev"},{"key":"key\n\t\t\t\t20170224031620_CIT0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1042\/bj3530193","article-title":"Dual DNA-binding specificity of peroxisome-proliferator-activated receptor \u03b3 controlled by heterodimer formation with retinoid X receptor alpha","volume":"353","year":"2001","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224031620_CIT0031","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1016\/j.ydbio.2005.09.043","article-title":"Molecular evidence for a critical period in mural trophoblast development in bovine blastocysts","volume":"288","year":"2005","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0032","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1530\/REP-10-0174","article-title":"A small set of extra-embryonic genes defines a new landmark for bovine embryo staging","volume":"141","year":"2011","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0033","first-page":"365","article-title":"Gene expression in elongating and gastrulating embryos from ruminants","volume":"64","year":"2007","journal-title":"Soc Reprod Fert Suppl"},{"key":"key\n\t\t\t\t20170224031620_CIT0034","first-page":"19","article-title":"Conceptus elongation in cattle: genes, models and questions","volume":"134","year":"2011","journal-title":"Anim Reprod Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0035","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1095\/biolreprod.111.092643","article-title":"RNA sequencing reveals novel gene clusters in bovine conceptuses associated with maternal recognition of pregnancy and implantation","volume":"85","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0036","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.matbio.2010.04.001","article-title":"Secreted phosphoprotein 1 binds integrins to initiate multiple cell signaling pathways, including FRAP1\/mTOR, to support attachment and force-generated migration of trophectoderm cells","volume":"29","year":"2010","journal-title":"Matrix Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0037","first-page":"3025","article-title":"Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions","volume":"122","year":"2009","journal-title":"J Cell Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0038","doi-asserted-by":"crossref","first-page":"948","DOI":"10.1038\/nmat3791","article-title":"Sharing the force","volume":"12","year":"2013","journal-title":"Nat Mater"},{"key":"key\n\t\t\t\t20170224031620_CIT0039","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1038\/nmat3772","article-title":"Molecular mechanisms of cellular mechanosensing","volume":"12","year":"2013","journal-title":"Nat Mater"},{"key":"key\n\t\t\t\t20170224031620_CIT0040","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1110\/ps.9.8.1594","article-title":"The L6 membrane proteins\u2013a new four-transmembrane superfamily","volume":"9","year":"2000","journal-title":"Protein Sci"},{"issue":"(8)","key":"key\n\t\t\t\t20170224031620_CIT0041","first-page":"3272","article-title":"The L6 protein TM4SF1 is critical for endothelial cell function and tumor angiogenesis","volume":"69","year":"2009","journal-title":"Cancer Res"},{"key":"key\n\t\t\t\t20170224031620_CIT0042","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s10456-011-9218-0","article-title":"TM4SF1: a tetraspanin-like protein necessary for nanopodia formation and endothelial cell migration","volume":"14","year":"2011","journal-title":"Angiogenesis"},{"key":"key\n\t\t\t\t20170224031620_CIT0043","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/(SICI)1097-0169(1997)38:3<250::AID-CM3>3.0.CO;2-9","article-title":"Fibroblast transgelin and smooth muscle SM22A are the same protein, the expression of which is down-regulated in many cell lines","volume":"38","year":"1997","journal-title":"Cell Motil Cytoskel"},{"key":"key\n\t\t\t\t20170224031620_CIT0044","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.biocel.2008.02.011","article-title":"Transgelin: an actin-binding protein and tumour suppressor","volume":"41","year":"2009","journal-title":"Int J Biochem Cell Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0045","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.jmb.2003.09.012","article-title":"The muscle ankyrin repeat proteins: CARP, ankrd2\/Arpp and DARP as a family of titin filament based stress response molecules","volume":"333","year":"2003","journal-title":"J Mol Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0046","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/35025229","article-title":"Thrombin signalling and protease-activated receptors","volume":"407","year":"2000","journal-title":"Nature"},{"key":"key\n\t\t\t\t20170224031620_CIT0047","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1038\/381516a0","article-title":"Role of the thrombin receptor in development and evidence for a second receptor","volume":"381","year":"1996","journal-title":"Nature"},{"issue":"(5)","key":"key\n\t\t\t\t20170224031620_CIT0048","first-page":"677","article-title":"Thrombin regulates the metastatic potential of human rhabdomyosarcoma cells: distinct role of PAR1 and PAR3 signaling","volume":"8","year":"2010","journal-title":"Mol Cancer Res"},{"key":"key\n\t\t\t\t20170224031620_CIT0049","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.cell.2004.12.018","article-title":"PAR1 is a matrix metalloprotease-1 receptor that promotes invasion and tumorigenesis of breast cancer cells","volume":"120","year":"2005","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170224031620_CIT0050","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1097\/MPA.0b013e31829f0b81","article-title":"Proteinase-activated receptors differentially modulate in vitro invasion of human pancreatic adenocarcinoma PANC-1 cells in correlation with changes in the expression of CDC42 protein","volume":"43","year":"2014","journal-title":"Pancreas"},{"key":"key\n\t\t\t\t20170224031620_CIT0051","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1083\/jcb.200608093","article-title":"Vascular endothelial growth factor can signal through platelet-derived growth factor receptors","volume":"177","year":"2007","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0052","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1681\/ASN.V94583","article-title":"Thrombin regulates PDGF expression in bovine glomerular endothelial cells","volume":"9","year":"1998","journal-title":"Am Soc Nephrol"},{"key":"key\n\t\t\t\t20170224031620_CIT0053","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1046\/j.1538-7836.2003.00208.x","article-title":"Thrombin induces angiogenesis and vascular endothelial growth factors expression in human endothelial cells: possible relevance to HIF-1alpha","volume":"1","year":"2003","journal-title":"J Thromb Haemost"},{"key":"key\n\t\t\t\t20170224031620_CIT0054","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1083\/jcb.141.4.1061","article-title":"Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis","volume":"141","year":"1998","journal-title":"J Cell Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0055","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1095\/biolreprod.111.094722","article-title":"Uterine histotroph and conceptus development: select nutrients and secreted phosphoprotein 1 affect mechanistic target of rapamycin cell signaling in ewes","volume":"85","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0056","first-page":"75","article-title":"Functional role of arginine during the peri-implantation period of pregnancy. III. Arginine stimulates proliferation and interferon tau production by ovine trophectoderm cells via nitric oxide and polyamine-TSC2-MTOR signaling pathways","volume":"92","year":"2015","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0057","doi-asserted-by":"crossref","first-page":"2852","DOI":"10.1096\/fj.13-248757","article-title":"Functional role of arginine during the peri-implantation period of pregnancy. I. Consequences of loss of function of arginine transporter SLC7A1 mRNA in ovine conceptus trophectoderm","volume":"28","year":"2014","journal-title":"FASEB J"},{"key":"key\n\t\t\t\t20170224031620_CIT0058","first-page":"59","article-title":"Functional role of arginine during the peri-implantation period of pregnancy. II. Consequences of loss of function of nitric oxide synthase NOS3 mRNA in ovine conceptus trophectoderm","volume":"91","year":"2014","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0059","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1071\/RD12266","article-title":"Contributions of an animal scientist to understanding the biology of the uterus and pregnancy","volume":"25","year":"2013","journal-title":"Reprod Fert Dev"},{"key":"key\n\t\t\t\t20170224031620_CIT0060","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/S0303-7207(97)00097-X","article-title":"Differential expression of the growth hormone receptor and its transcript in bovine uterus and placenta","volume":"131","year":"1997","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224031620_CIT0061","doi-asserted-by":"crossref","first-page":"1826","DOI":"10.1095\/biolreprod64.6.1826","article-title":"Growth hormone (GH)\/GH receptor expression and GH-mediated effects during early bovine embryogenesis","volume":"64","year":"2001","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0062","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1677\/joe.0.1650231","article-title":"The expression of the IGF system in the bovine uterus throughout the oestrous cycle and early pregnancy","volume":"165","year":"2000","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224031620_CIT0063","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1530\/rep.0.1220601","article-title":"Changes in the relative abundance of mRNA transcripts for insulin-like growth factor (IGF-I and IGF-II) ligands and their receptors (IGF-IR\/IGF-IIR) in preimplantation bovine embryos derived from different in vitro systems","volume":"122","year":"2001","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0064","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.3168\/jds.2007-0664","article-title":"Growth hormone receptor, insulin-like growth factor (IGF)-1, and IGF-binding protein-2 expression in the reproductive tissues of early postpartum dairy cows","volume":"91","year":"2008","journal-title":"J Dairy Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0065","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.3168\/jds.S0022-0302(98)75747-9","article-title":"Role of the insulin-like growth factor system in uterine function and placental development in ruminants","volume":"81","year":"1998","journal-title":"J Dairy Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0066","doi-asserted-by":"crossref","first-page":"1409","DOI":"10.1095\/biolreprod61.6.1409","article-title":"Effects of recombinant ovine interferon tau, placental lactogen, and growth hormone on the ovine uterus","volume":"61","year":"1999","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0067","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/mrd.1145","article-title":"Growth hormone inhibits apoptosis in in vitro produced bovine embryos","volume":"61","year":"2002","journal-title":"Mol Reprod Dev"},{"key":"key\n\t\t\t\t20170224031620_CIT0068","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/S0093-691X(01)00694-X","article-title":"Effects of growth hormone and insulin-like growth factor-I on development of in vitro derived bovine embryos","volume":"57","year":"2002","journal-title":"Theriogenology"},{"key":"key\n\t\t\t\t20170224031620_CIT0069","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1530\/rep.0.1250327","article-title":"Growth hormone, insulin-like growth factor I and cell proliferation in the mouse blastocyst","volume":"125","year":"2003","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0070","doi-asserted-by":"crossref","first-page":"3360","DOI":"10.3168\/jds.S0022-0302(06)72373-6","article-title":"Pregnancy, bovine somatotropin, and dietary n-3 fatty acids in lactating dairy cows: I. Ovarian, conceptus, and growth hormone-insulin-like growth factor system responses","volume":"89","year":"2006","journal-title":"J Dairy Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0071","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1146\/annurev.med.53.082901.104018","article-title":"The mechanisms of action of PPARs","volume":"53","year":"2002","journal-title":"Annual Rev Med"},{"key":"key\n\t\t\t\t20170224031620_CIT0072","first-page":"409168","article-title":"PPARG: gene expression regulation and next-generation sequencing for unsolved issues","volume":"2010","year":"2010","journal-title":"PPAR Res"},{"key":"key\n\t\t\t\t20170224031620_CIT0073","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.jri.2011.05.003","article-title":"PPAR\u03b3 and human trophoblast differentiation","volume":"90","year":"2011","journal-title":"J Reprod Immunol"},{"key":"key\n\t\t\t\t20170224031620_CIT0074","doi-asserted-by":"crossref","first-page":"4312","DOI":"10.1073\/pnas.94.9.4312","article-title":"Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors \u03b1 and \u03b4","volume":"94","year":"1997","journal-title":"Proc Natl Acad Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0075","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0092-8674(00)81574-3","article-title":"Oxidized LDL regulates macrophage gene expression through ligand activation of PPAR\u03b3","volume":"93","year":"1998","journal-title":"Cell"},{"key":"key\n\t\t\t\t20170224031620_CIT0076","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/S1097-2765(00)80209-9","article-title":"PPAR\u03b3 is required for placental, cardiac, and adipose tissue development","volume":"4","year":"1999","journal-title":"Mol Cell"},{"key":"key\n\t\t\t\t20170224031620_CIT0077","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.mce.2006.02.009","article-title":"The pleiotropic function of PPAR\u03b3 in the placenta","volume":"249","year":"2006","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224031620_CIT0078","doi-asserted-by":"crossref","first-page":"3625","DOI":"10.1210\/en.2007-0211","article-title":"BarakY, Biron-Shental T, Nelson MD, Sadovsky Y. Ligand-activated PPARg alters placental morphology and placental fatty acid uptake in mice","volume":"148","year":"2007","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224031620_CIT0079","first-page":"143","article-title":"Placental PPAR\u03b3 regulates spatiotemporally diverse genes and a unique metabolic network","year":"2012","journal-title":"Dev Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0080","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1530\/rep.1.00799","article-title":"Developmental regulation of prostacyclin synthase and prostacyclin receptors in the ovine uterus and conceptus during the peri-implantation period","volume":"131","year":"2006","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0081","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1095\/biolreprod.114.123877","article-title":"Peroxisome proliferator activator receptor gamma (PPARG) regulates conceptus elongation in sheep","volume":"92","year":"2015","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0082","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1016\/j.placenta.2011.08.014","article-title":"Expression and localization of DLX3, PPARG and SP1 in bovine trophoblast during binucleated cell differentiation","volume":"32","year":"2011","journal-title":"Placenta"},{"key":"key\n\t\t\t\t20170224031620_CIT0083","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1124\/pr.56.3.3","article-title":"Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition","volume":"56","year":"2004","journal-title":"Pharmacol Rev"},{"key":"key\n\t\t\t\t20170224031620_CIT0084","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1095\/biolreprod.110.089979","article-title":"Prostaglandins regulate conceptus elongation and mediate effects of interferon tau on the ovine uterine endometrium","volume":"84","year":"2011","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0085","first-page":"9","article-title":"Conceptus-derived prostaglandins regulate endometrial function in sheep","volume":"87","year":"2012","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0086","doi-asserted-by":"crossref","first-page":"13029","DOI":"10.1074\/jbc.M109546200","article-title":"Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor and oxidized alkyl phospholipids from oxidized low density lipoprotein","volume":"277","year":"2002","journal-title":"J. Biol Chem"},{"key":"key\n\t\t\t\t20170224031620_CIT0087","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1096\/fj.02-1075fje","article-title":"PPAR\u03b3 ligands induce prostaglandin production in vascular smooth muscle cells: indomethacin acts as a peroxisome proliferator-activated receptor-antagonist","volume":"17","year":"2003","journal-title":"FASEB J"},{"key":"key\n\t\t\t\t20170224031620_CIT0088","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1042\/BJ20070089","article-title":"Peroxisome-proliferator-activated receptors and the control of levels of prostaglandin-endoperoxide synthase 2 by arachidonic acid in the bovine uterus","volume":"406","year":"2007","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224031620_CIT0089","doi-asserted-by":"crossref","first-page":"919","DOI":"10.2527\/jas1973.365919x","article-title":"Control by progesterone of the concentration of lipid droplets in epithelial cells of the sheep endometrium","volume":"36","year":"1973","journal-title":"J Anim Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0090","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1530\/jrf.0.0790569","article-title":"Assessment of sheep blastocyst effects on neutral lipids in the uterine caruncular epithelium","volume":"79","year":"1987","journal-title":"J Reprod Fert"},{"key":"key\n\t\t\t\t20170224031620_CIT0091","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1095\/biolreprod27.2.431","article-title":"Metabolism of arachidonic acid in vitro by bovine blastocysts and endometrium","volume":"27","year":"1982","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0092","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1530\/REP-09-0081","article-title":"Quantitative characterization of prostaglandins in the uterus of early pregnant cattle","volume":"138","year":"2009","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0093","first-page":"97","article-title":"Intraluteal prostaglandin biosynthesis and signaling are selectively directed towards PGF2alpha during luteolysis but towards PGE2 during the establishment of pregnancy in sheep","volume":"87","year":"2012","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0094","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1530\/REP-13-0165","article-title":"Conceptus-derived prostaglandins regulate gene expression in the endometrium prior to pregnancy recognition in ruminants","volume":"146","year":"2013","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0095","doi-asserted-by":"crossref","first-page":"6248","DOI":"10.1073\/pnas.87.16.6248","article-title":"Selective incorporation of (15S)-hydroxyeicosatetraenoic acid in phosphatidylinositol of human neutrophils: Agonist-induced deacylation and transformation of stored hydroxyeicosanoids","volume":"87","year":"1990","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224031620_CIT0096","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.prostaglandins.2004.09.013","article-title":"Lipid signaling in embryo implantation","volume":"77","year":"2005","journal-title":"Prostag Lip Med"},{"key":"key\n\t\t\t\t20170224031620_CIT0097","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1161\/01.ATV.0000222960.43792.ff","article-title":"Lipoxygenase pathways as mediators of early inflammatory events in atherosclerosis","volume":"26","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"key\n\t\t\t\t20170224031620_CIT0098","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.prostaglandins.2008.12.002","article-title":"Biology of endocannabinoid synthesis system","volume":"89","year":"2009","journal-title":"Prostag Lip Med"},{"key":"key\n\t\t\t\t20170224031620_CIT0099","doi-asserted-by":"crossref","first-page":"14914","DOI":"10.1073\/pnas.2436379100","article-title":"Differential G protein-coupled cannabinoid receptor signaling by anandamide directs blastocyst activation for implantation","volume":"100","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"key\n\t\t\t\t20170224031620_CIT0100","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1093\/humupd\/dmu004","article-title":"Endocannabinoids as biomarkers of human reproduction","volume":"20","year":"2014","journal-title":"Hum Reprod Update"},{"key":"key\n\t\t\t\t20170224031620_CIT0101","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/sj.bjp.0707423","article-title":"Cannabinoids go nuclear: evidence for activation of peroxisome proliferator-activated receptors","volume":"152","year":"2007","journal-title":"Brit J Pharm"},{"key":"key\n\t\t\t\t20170224031620_CIT0102","first-page":"23513","article-title":"Cannabinoids: a new group of agonists of PPARs","volume":"2007","year":"2007","journal-title":"PPAR Res"},{"issue":"(12)","key":"key\n\t\t\t\t20170224031620_CIT0103","first-page":"7481","article-title":"Release of prostaglandins and monohydroxy and trihydroxy metabolites of linoleic and arachidonic acids by adult and fetal aortae and ductus arteriosus","volume":"260","year":"1985","journal-title":"J Biol Chem"},{"key":"key\n\t\t\t\t20170224031620_CIT0104","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.bbagen.2009.07.026","article-title":"Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential","volume":"1790","year":"2009","journal-title":"Biochim Biophys Acta"},{"key":"key\n\t\t\t\t20170224031620_CIT0105","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1161\/HYPERTENSIONAHA.114.04760","article-title":"Activation of nuclear factor erythroid 2\u2013related factor 2 coordinates dimethylarginine dimethylaminohydrolase\/PPAR-\u03b3\/endothelial nitric oxide synthase pathways that enhance nitric oxide generation in human glomerular endothelial cells","volume":"65","year":"2015","journal-title":"Hypertension"},{"key":"key\n\t\t\t\t20170224031620_CIT0106","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1530\/REP-13-0010","article-title":"Proteomic analysis of uterine fluid during the pre-implantation period of pregnancy in cattle","volume":"147","year":"2014","journal-title":"Reproduction"},{"key":"key\n\t\t\t\t20170224031620_CIT0107","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1152\/physiolgenomics.00067.2012","article-title":"Evidence for an early endometrial response to pregnancy in cattle: both dependent upon and independent of interferon tau","volume":"44","year":"2012","journal-title":"Physiol Genom"},{"key":"key\n\t\t\t\t20170224031620_CIT0108","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1042\/bj2560807","article-title":"Incorporation of lipoxygenase products into cholesteryl esters by acyl-CoA: cholesterol acyltransferase in cholesterol-rich macrophages","volume":"256","year":"1988","journal-title":"Biochem J"},{"key":"key\n\t\t\t\t20170224031620_CIT0109","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1530\/ror.0.0050067","article-title":"Evolution of mammalian pregnancy in the presence of the maternal immune system","volume":"5","year":"2000","journal-title":"Rev Reprod"},{"key":"key\n\t\t\t\t20170224031620_CIT0110","first-page":"267","article-title":"Major histocompatibility antigen expression on the bovine placenta: its relationship to abnormal pregnancies and retained placenta","volume":"82\u201383","year":"2004","journal-title":"Anim Reprod Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0111","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1016\/j.molimm.2011.04.011","article-title":"Complement activation in animal and human pregnancies as a model for immunological recognition","volume":"48","year":"2011","journal-title":"Mol Immunol"},{"key":"key\n\t\t\t\t20170224031620_CIT0112","first-page":"64","article-title":"Maternal-embryo interaction leading up to the initiation of implantation of pregnancy in cattle","volume":"1","year":"2014","journal-title":"Animal"},{"key":"key\n\t\t\t\t20170224031620_CIT0113","doi-asserted-by":"crossref","first-page":"4907","DOI":"10.3168\/jds.2013-7802","article-title":"Effects of supplemental progesterone after artificial insemination on expression of interferon-stimulated genes and fertility in dairy cows","volume":"97","year":"2014","journal-title":"J Dairy Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0114","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.anireprosci.2014.08.008","article-title":"Effect of exogenous progesterone supplementation in the early luteal phase post-insemination on pregnancy per artificial insemination in Holstein\u2013Friesian cows","volume":"150","year":"2014","journal-title":"Anim Reprod Sci"},{"key":"key\n\t\t\t\t20170224031620_CIT0115","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1016\/0093-691X(95)00279-H","article-title":"Synchronization of ovulation in dairy cows using PGF2alpha and GnRH","volume":"44","year":"1995","journal-title":"Theriogenology"},{"key":"key\n\t\t\t\t20170224031620_CIT0116","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1017\/S1751731114000858","article-title":"Synchronisation of ovulation for management of reproduction in dairy cows","volume":"8","year":"2014","journal-title":"Animal"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/94\/4\/97","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T18:58:02Z","timestamp":1718391482000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod.115.134908"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4,1]]},"references-count":116,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod.115.134908","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,4,1]]}}}