{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T05:17:49Z","timestamp":1761196669980},"reference-count":39,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,7,1]]},"DOI":"10.1095\/biolreprod61.1.40","type":"journal-article","created":{"date-parts":[[2005,10,31]],"date-time":"2005-10-31T23:08:20Z","timestamp":1130800100000},"page":"40-45","source":"Crossref","is-referenced-by-count":32,"title":["Prostaglandins and Leukotriene B4 Are Potent Inhibitors of 11\u03b2-Hydroxysteroid Dehydrogenase Type 2 Activity in Human Choriocarcinoma JEG-3 Cells1"],"prefix":"10.1093","volume":"61","author":[{"given":"D.B.","family":"Hardy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L.E.","family":"Pereria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224180857_R1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/0140-6736(93)90148-A","article-title":"Dysfunction of placental glucocorticoid barrier: link between fetal environment and adult hypertension?","volume":"341","year":"1993","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170224180857_R2","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S0039-128X(96)00165-1","article-title":"Glucocorticoids, feto-placental 11\u03b2-hydroxysteroid dehydrogenase type 2, and the early life origins of adult disease.","volume":"62","year":"1997","journal-title":"Steroids"},{"key":"key\n\t\t\t\t20170224180857_R3","first-page":"608","article-title":"Actions of placental and fetal adrenal steroid hormones in primate pregnancy.","volume":"16","year":"1995","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224180857_R4","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1046\/j.1365-2265.1997.1230939.x","article-title":"Placental 11\u03b2-hydroxysteroid dehydrogenase: a key regulator of fetal glucocorticoid exposure.","volume":"46","year":"1997","journal-title":"Clin Endocrinol"},{"key":"key\n\t\t\t\t20170224180857_R5","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1530\/ror.0.0020129","article-title":"Placental 11\u03b2-hydroxysteroid dehydrogenase: barrier to maternal glucocorticoids.","volume":"2","year":"1997","journal-title":"Rev Reprod"},{"key":"key\n\t\t\t\t20170224180857_R6","first-page":"2203","article-title":"Immunohistochemical localization of the 11\u03b2-hydroxysteroid dehydrogenase type II enzyme in human kidney and placenta.","volume":"80","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224180857_R7","first-page":"885","article-title":"Type 2 11\u03b2-hydroxysteroid dehydrogenase messenger ribonucleic acid and activity in human placenta and fetal membranes: its relationship to birth weight and putative role in fetal adrenal steroidogenesis.","volume":"80","year":"1995","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224180857_R8","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/0140-6736(93)90138-7","article-title":"Glucocorticoid exposure in utero: new model for adult hypertension.","volume":"341","year":"1993","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170224180857_R9","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1093\/humrep\/13.4.799","article-title":"11\u03b2-Hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction.","volume":"13","year":"1998","journal-title":"Hum Reprod"},{"key":"key\n\t\t\t\t20170224180857_R10","volume-title":"Program of the Xth International Congress on Hormonal Steroids","year":"1998"},{"key":"key\n\t\t\t\t20170224180857_R11","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1046\/j.1365-2265.1996.677500.x","article-title":"Apparent mineralocorticoid excess due to 11\u03b2-hydroxysteroid dehydrogenase deficiency: a possible cause of intrauterine growth retardation.","volume":"44","year":"1996","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key\n\t\t\t\t20170224180857_R12","first-page":"135","article-title":"11\u03b2-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess.","volume":"18","year":"1997","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224180857_R13","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/0039-128X(95)00201-Z","article-title":"11\u03b2-Hydroxysteroid dehydrogenases of the choriocarcinoma cell line JEG-3 and their inhibition by glycyrrhetinic acid and other natural substances.","volume":"61","year":"1996","journal-title":"Steroids"},{"key":"key\n\t\t\t\t20170224180857_R14","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1677\/jme.0.0160269","article-title":"Regulation of 11\u03b2-hydroxysteroid dehydrogenase type 2 activity and mRNA in human choriocarcinoma cells.","volume":"16","year":"1996","journal-title":"J Mol Endocrinol"},{"key":"key\n\t\t\t\t20170224180857_R15","doi-asserted-by":"crossref","first-page":"4912","DOI":"10.1210\/endo.138.11.5544","article-title":"Differential regulation of 11\u03b2-hydroxysteroid dehydrogenase type 1 and 2 by nitric oxide in cultured human placental trophoblast and chorionic cell preparation.","volume":"138","year":"1997","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180857_R16","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1095\/biolreprod58.6.1379","article-title":"Regulation of 11\u03b2-hydroxysteroid dehydrogenase type 2 by progesterone, estrogen and cyclic AMP pathway in cultured human placental trophoblasts.","volume":"58","year":"1998","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180857_R17","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1095\/biolreprod60.3.541","article-title":"Retinoic acid stimulates the expression of 11\u03b2-hydroxysteroid dehydrogenase type 2 in human choriocarcinoma JEG-3 cells.","volume":"60","year":"1999","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180857_R18","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1210\/endo-122-1-78","article-title":"The regulation of transplacental cortisol-cortisone metabolism by estrogen in pregnant baboons.","volume":"122","year":"1988","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180857_R19","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1210\/endo-127-4-1735","article-title":"Interconversion of cortisol and cortisone in baboon trophoblast and decidua cells in culture.","volume":"127","year":"1990","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180857_R20","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1210\/endo-126-5-2742","article-title":"Regulation of 11\u03b2-hydroxysteroid dehydrogenase activity in the baboon placenta by estrogen.","volume":"126","year":"1990","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180857_R21","first-page":"156","article-title":"Peptide signaling in human placenta and membranes: autocrine, paracrine, and endocrine mechanisms.","volume":"17","year":"1996","journal-title":"Endocr Rev"},{"key":"key\n\t\t\t\t20170224180857_R22","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/S0143-4004(96)90043-0","article-title":"Arachidonic metabolism in human placenta, fetal membranes, decidua, and myometrium: lipoxygenase and cytochrome p450 metabolites as main products in HPLC profiles.","volume":"17","year":"1996","journal-title":"Placenta"},{"key":"key\n\t\t\t\t20170224180857_R23","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/0303-7207(96)03855-5","article-title":"Analysis of the promoter of the NAD+ dependent 11\u03b2-hydroxysteroid dehydrogenase (HSD11K) gene in JEG-3 human choriocarcinoma cells.","volume":"121","year":"1996","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224180857_R24","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0303-7207(89)90185-8","article-title":"Effects of 8-bromo-cAMP on expression of endocrine functions by cultured human trophoblast cells: regulation of specific mRNAs.","volume":"61","year":"1989","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224180857_R25","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0165-0378(95)00931-A","article-title":"Tumor necrosis factor-\u03b1 affects in vitro hormone production by JEG-3 choriocarcinoma cell cultures.","volume":"29","year":"1995","journal-title":"J Reprod Immunol"},{"key":"key\n\t\t\t\t20170224180857_R26","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0952-3278(97)90573-1","article-title":"Tumour cell-endothelial cell interactions: evidence for roles for lipoxygenase products of arachidonic acid in metastasis.","volume":"56","year":"1997","journal-title":"Prostaglandins Leukot Essent Fatty Acids"},{"key":"key\n\t\t\t\t20170224180857_R27","doi-asserted-by":"crossref","first-page":"R11","DOI":"10.1016\/0303-7207(94)90176-7","article-title":"Cloning and tissue distribution of the human 11\u03b2-hydroxysteroid dehydrogenase type 2 enzyme","volume":"105","year":"1994","journal-title":"Mol Cell Endocrinol"},{"key":"key\n\t\t\t\t20170224180857_R28","doi-asserted-by":"crossref","first-page":"9179","DOI":"10.1093\/nar\/12.23.9179","article-title":"The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species.","volume":"12","year":"1984","journal-title":"Nucleic Acids Res"},{"key":"key\n\t\t\t\t20170224180857_R29","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1210\/endo.138.3.5008","article-title":"Retinoic acids increase 17\u03b2-hydroxysteroid dehydrogenase type 1 expression in JEG-3 and T47D cells, but the stimulation is potentiated by epidermal growth factor, 12-O-tetradecanoylphorbol-13-acetate, and cAMP only in JEG-3 cells.","volume":"138","year":"1997","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180857_R30","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1471-0528.1989.tb01581.x","article-title":"Leukotrienes in human umbilical plasma at birth.","volume":"96","year":"1989","journal-title":"Br J Obstet Gynaecol"},{"key":"key\n\t\t\t\t20170224180857_R31","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1677\/joe.0.0690413","article-title":"Distribution of prostaglandins E2 and F2\u03b1 within the foetoplacental unit throughout human pregnancy.","volume":"69","year":"1976","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224180857_R32","first-page":"985","volume-title":"The Physiology of Reproduction","year":"1994"},{"key":"key\n\t\t\t\t20170224180857_R33","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1016\/S0095-5108(18)30265-3","article-title":"The role of prostaglandins in labor and delivery.","volume":"22","year":"1995","journal-title":"Clin Perinat"},{"key":"key\n\t\t\t\t20170224180857_R34","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1210\/jcem-54-6-1251","article-title":"The lack of influence of labor on human placental 11\u03b2-hydroxysteroid dehydrogenase activity.","volume":"54","year":"1982","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224180857_R35","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1055\/s-2007-1012393","article-title":"11\u03b2-Hydroxysteroid dehydrogenase activity of the human placenta during pregnancy.","volume":"18","year":"1986","journal-title":"Horm Metab Res"},{"key":"key\n\t\t\t\t20170224180857_R36","first-page":"300","article-title":"Differential expression of 11\u03b2-hydroxysteroid dehydrogenase types 1 and 2 in human placenta and fetal membranes.","volume":"82","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224180857_R37","doi-asserted-by":"crossref","first-page":"684","DOI":"10.7326\/0003-4819-121-9-199411010-00010","article-title":"The role of leukotrienes in inflammation.","volume":"121","year":"1994","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t20170224180857_R38","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1055\/s-2007-994417","article-title":"The very low birthweight infant: maternal complications leading to preterm birth, placental lesions, and intrauterine growth.","volume":"12","year":"1995","journal-title":"Am J Perinat"},{"key":"key\n\t\t\t\t20170224180857_R39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1600-0897.1987.tb00162.x","article-title":"Fibrinoid and trophoblastic necrosis with massive chronic intervillositis: an extreme variant of villitis of unknown etiology.","volume":"15","year":"1987","journal-title":"Am J Reprod Immunol Microbiol"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/61\/1\/40\/10591674\/biolreprod0040.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T22:04:39Z","timestamp":1554329079000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod61.1.40"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,7,1]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,7,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod61.1.40","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,7,1]]}}}