{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T15:59:13Z","timestamp":1776355153715,"version":"3.51.2"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[1999,9,1]]},"DOI":"10.1095\/biolreprod61.3.635","type":"journal-article","created":{"date-parts":[[2005,10,31]],"date-time":"2005-10-31T23:08:20Z","timestamp":1130800100000},"page":"635-642","source":"Crossref","is-referenced-by-count":37,"title":["Autoimmune Ovarian Inflammation Triggered by Proinflammatory (Th1) T Cells Is Compatible with Normal Ovarian Function in Mice1"],"prefix":"10.1093","volume":"61","author":[{"given":"Harini","family":"Bagavant","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sallie","family":"Adams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Terranova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alice","family":"Chang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frances W.","family":"Kraemer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yahuan","family":"Lou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ken","family":"Kasai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"An Ming","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth S.K.","family":"Tung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224180653_R1","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1097\/00004347-199007000-00001","article-title":"Autoimmune oophoritis: a clinicopathologic assessment of 12 cases.","volume":"9","year":"1990","journal-title":"Int J Gynecol Pathol"},{"key":"key\n\t\t\t\t20170224180653_R2","first-page":"509","article-title":"Autoimmunity in endocrine disease.","volume":"36","year":"1980","journal-title":"Recent Prog Horm Res"},{"key":"key\n\t\t\t\t20170224180653_R3","first-page":"883","article-title":"Immunological aspects of premature ovarian failure associated with idiopathic Addison's disease.","volume":"2","year":"1968","journal-title":"Lancet"},{"key":"key\n\t\t\t\t20170224180653_R4","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0015-0282(16)45687-6","article-title":"Premature ovarian failure\u2014evidence for the autoimmune mechanism.","volume":"36","year":"1981","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224180653_R5","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00004347-198202000-00006","article-title":"Premature hypergonadotropic ovarian failure: clinicopathological study of 19 cases.","volume":"1","year":"1982","journal-title":"Int J Gynecol Pathol"},{"key":"key\n\t\t\t\t20170224180653_R6","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.4049\/jimmunol.140.4.1132","article-title":"Antigen-specific inhibition of immune interferon production by suppressor cells of autoimmune encephalomyelitis.","volume":"140","year":"1988","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170224180653_R7","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1172\/JCI115055","article-title":"Essential role for interferon gamma and interleukin 6 in autoimmune insulin dependant diabetes in NOD\/Wehi mice.","volume":"87","year":"1991","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224180653_R8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0163-7258(95)02064-0","article-title":"Cytokines in the ovary: pathophysiology and potential for pharmacological intervention.","volume":"69","year":"1996","journal-title":"Pharmacol Ther"},{"key":"key\n\t\t\t\t20170224180653_R9","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1111\/j.1600-0897.1991.tb01089.x","article-title":"Immunology of ovarian failure.","volume":"25","year":"1991","journal-title":"Am J Reprod Immunol"},{"key":"key\n\t\t\t\t20170224180653_R10","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1095\/biolreprod46.4.523","article-title":"Analysis of contraceptive potential of antibodies against native and deglycosylated porcine ZP3 in vivo and in vitro.","volume":"46","year":"1992","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180653_R11","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1016\/S0015-0282(16)57863-7","article-title":"Immunization of monkeys with recombinant complimentary deoxyribonucleic acid expressed zona pellucida proteins.","volume":"64","year":"1995","journal-title":"Fertil Steril"},{"key":"key\n\t\t\t\t20170224180653_R12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF00344296","article-title":"Genetic susceptibility to post-thymectomy autoimmune diseases in mice.","volume":"14","year":"1981","journal-title":"Immunogenetics"},{"key":"key\n\t\t\t\t20170224180653_R13","first-page":"293","article-title":"Murine autoimmune oophoritis, epididymoorchitis and gastritis induced by day 3 thymectomy.","volume":"126","year":"1987","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t20170224180653_R14","doi-asserted-by":"crossref","first-page":"4758","DOI":"10.1073\/pnas.92.11.4758","article-title":"Aodl, the immunoregulatory locus controlling abrogation of tolerance in neonatal thymectomy induced autoimmune ovarian dysgenesis, maps to mouse chromosome 16.","volume":"92","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"key\n\t\t\t\t20170224180653_R15","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1084\/jem.183.2.631","article-title":"Aod2, the locus controlling development of atrophy in neonatal thymectomy induced autoimmune ovarian dysgenesis, co-localizes with IL-2, Fgfb and Idd3.","volume":"183","year":"1996","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170224180653_R16","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1172\/JCI115572","article-title":"Autoimmune disease of the ovary induced by a ZP3 peptide from the mouse zona pellucida.","volume":"89","year":"1992","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224180653_R17","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.4049\/jimmunol.155.5.2715","article-title":"A zona pellucida 3 peptide vaccine induces antibodies and reversible infertility without ovarian pathology.","volume":"155","year":"1995","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170224180653_R18","first-page":"38","volume-title":"the mouse: its reproduction and development","year":"1993"},{"key":"key\n\t\t\t\t20170224180653_R19","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/0022-1759(94)90370-0","article-title":"Constructing polycompetitor cDNAs for quantitative PCR","volume":"175","year":"1994","journal-title":"J Immunol Methods"},{"key":"key\n\t\t\t\t20170224180653_R20","doi-asserted-by":"crossref","first-page":"554","DOI":"10.4049\/jimmunol.147.2.554","article-title":"Analysis of cytokine gene expression during fetal thymic ontogeny using polymerase chain reaction.","volume":"147","year":"1991","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170224180653_R21","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1530\/jrf.0.0170555","article-title":"Proposal for classification of oocytes and follicles in the mouse ovary.","volume":"17","year":"1968","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224180653_R22","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1530\/jrf.0.0370277","article-title":"Cell kinetic studies of follicular atresia in the mouse ovary.","volume":"37","year":"1974","journal-title":"J Reprod Fertil"},{"key":"key\n\t\t\t\t20170224180653_R23","doi-asserted-by":"crossref","first-page":"5790","DOI":"10.4049\/jimmunol.151.10.5790","article-title":"T cell peptide of a self protein elicits autoantibody to the protein antigen: implications for specificity and pathogenetic role of antibody in autoimmunity.","volume":"151","year":"1993","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170224180653_R24","doi-asserted-by":"crossref","first-page":"3535","DOI":"10.4049\/jimmunol.156.9.3535","article-title":"Rapid induction of autoantibodies by endogenous ovarian antigens and activated T cells.","volume":"156","year":"1996","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170224180653_R25","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.4049\/jimmunol.136.7.2348","article-title":"Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins.","volume":"136","year":"1986","journal-title":"J Immunol"},{"key":"key\n\t\t\t\t20170224180653_R26","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1084\/jem.177.1.57","article-title":"Surface expression of alpha 4 integrin is required for entry into brain parenchyma.","volume":"177","year":"1993","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170224180653_R27","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1095\/biolreprod48.4.707","article-title":"Tumor necrosis factor a gene expression in mouse oocytes and follicular cells.","volume":"48","year":"1993","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180653_R28","first-page":"308","volume-title":"Pathology of Reproductive.","year":"1991"},{"key":"key\n\t\t\t\t20170224180653_R29","doi-asserted-by":"crossref","first-page":"1098","DOI":"10.1210\/endo.133.3.8103448","article-title":"Experimental autoimmune orchitis induced by testis and sperm antigen specific T cell clones: an important pathogenic cytokine is tumor necrosis factor.","volume":"133","year":"1993","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180653_R30","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1600-0897.1997.tb00192.x","article-title":"Review: cytokine involvement in ovarian processes.","volume":"37","year":"1997","journal-title":"Am J Reprod Immunol"},{"key":"key\n\t\t\t\t20170224180653_R31","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/0960-0760(92)90082-T","article-title":"The potential relevance of cytokines to ovarian physiology.","volume":"43","year":"1992","journal-title":"J Steroid Biochem"},{"key":"key\n\t\t\t\t20170224180653_R32","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1210\/endo.132.1.8419137","article-title":"Ovulatory effect of interleukin 1\u03b2 on the perfused rat ovary.","volume":"132","year":"1993","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180653_R33","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1210\/endo.137.5.8612534","article-title":"Fas\/Apo-1\/CD95 system as a mediator of granulosa cell apoptosis in ovarian follicle atresia.","volume":"137","year":"1996","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180653_R34","first-page":"206","article-title":"Mechanism of deletion of endothelial cells during regression of the corpus luteum.","volume":"51","year":"1984","journal-title":"Lab Invest"},{"key":"key\n\t\t\t\t20170224180653_R35","first-page":"503","article-title":"Effects of lipopolysaccharide on ovarian function in the pregnant mare serum gonadotropin-treated immature rat.","volume":"1","year":"1993","journal-title":"Endocr J"},{"key":"key\n\t\t\t\t20170224180653_R36","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/0002-9378(90)90425-7","article-title":"Induction of class II major histocompatibility complex antigen expression on human granulosa cells by interferon gamma: a potential mechanism contributing to autoimmune failure.","volume":"162","year":"1990","journal-title":"Am J Obstet Gynecol"},{"key":"key\n\t\t\t\t20170224180653_R37","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1600-065X.1991.tb00580.x","article-title":"Cytokine assays: role in evaluation of the pathogenesis of autoimmunity.","volume":"119","year":"1991","journal-title":"Immunol Rev"},{"key":"key\n\t\t\t\t20170224180653_R38","doi-asserted-by":"crossref","first-page":"989","DOI":"10.1084\/jem.186.7.989","article-title":"Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice.","volume":"186","year":"1997","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170224180653_R39","first-page":"375","article-title":"Experimental allergic encephalomyelitis: inhibition of clinical signs and paradoxical enhancement of lesion in second attacks.","volume":"101","year":"1980","journal-title":"Am J Pathol"},{"key":"key\n\t\t\t\t20170224180653_R40","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1084\/jem.183.4.1893","article-title":"Inhibition of leukotriene B4 receptor interaction suppresses eosinophil infiltration and disease pathology in murine model of experimental allergic encephalomyelitis.","volume":"183","year":"1996","journal-title":"J Exp Med"},{"key":"key\n\t\t\t\t20170224180653_R41","volume-title":"Keystone Symposium: T Lymphocyte Activation, Differentiation and Death","year":"1998"},{"key":"key\n\t\t\t\t20170224180653_R42","volume-title":"Serono Symposium: XIth Ovarian Workshop: Ovarian Cell Growth, Apoptosis and Cancer","year":"1996"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/61\/3\/635\/10592428\/biolreprod0635.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T07:58:05Z","timestamp":1736063885000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod61.3.635"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,9,1]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1999,9,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod61.3.635","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,9,1]]}}}