{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T16:25:33Z","timestamp":1791044733249,"version":"4.1.0"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2000,1,1]]},"DOI":"10.1095\/biolreprod62.1.45","type":"journal-article","created":{"date-parts":[[2005,10,31]],"date-time":"2005-10-31T18:08:20Z","timestamp":1130782100000},"page":"45-53","source":"Crossref","is-referenced-by-count":128,"title":["Endocrine Alterations That Underlie Endotoxin-Induced Disruption of the Follicular Phase in Ewes1"],"prefix":"10.1093","volume":"62","author":[{"given":"Deborah F.","family":"Battaglia","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly B.","family":"Krasa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasantha","family":"Padmanabhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Vigui\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred J.","family":"Karsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","reference":[{"key":"key\n\t\t\t\t20170224180721_R1","first-page":"368","article-title":"Suppression of preovulatory luteinizing hormone surges in heifers after intrauterine infusions of Escherichia coli endotoxin.","volume":"50","year":"1989","journal-title":"Am J Vet Res"},{"key":"key\n\t\t\t\t20170224180721_R2","first-page":"2454","article-title":"Stress and the menstrual cycle: relevance of cycle quality in the short- and long-term response to a 5-day endotoxin challenge during the follicular phase in the rhesus monkey.","volume":"83","year":"1998","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20170224180721_R3","first-page":"61","article-title":"Immune-neuroendocrine circuits: integrative role of cytokines.","volume":"13","year":"1992","journal-title":"Front Neuroendocrinol"},{"key":"key\n\t\t\t\t20170224180721_R4","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1172\/JCI112815","article-title":"Secretory products of macrophages.","volume":"79","year":"1987","journal-title":"J Clin Invest"},{"key":"key\n\t\t\t\t20170224180721_R5","doi-asserted-by":"crossref","first-page":"2424","DOI":"10.1210\/endo.133.6.8243260","article-title":"The chronic intracerebroventricular infusion of interleukin-1\u03b2 alters the activity of the hypothalamic-pituitary-gonadal axis of cycling rats. I. Effect on LHRH and gonadotropin biosynthesis and secretion.","volume":"133","year":"1993","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R6","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1210\/endo.138.4.5044","article-title":"Effect of immune and metabolic challenges on the luteinizing hormone-releasing hormone neuronal system in cycling female rats: an evaluation at the transcriptional level.","volume":"138","year":"1997","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R7","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/0006-8993(93)90463-W","article-title":"Interleukin-1\u03b2 inhibits the endogenous expression of the early gene c-fos located within the nucleus of LH-RH neurons and interferes with hypothalamic LH-RH release during proestrus in the rat.","volume":"613","year":"1993","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20170224180721_R8","doi-asserted-by":"crossref","first-page":"4273","DOI":"10.1210\/endo.138.10.5449","article-title":"Endotoxin inhibits the reproductive neuroendocrine axis while stimulating adrenal steroids: a simultaneous view from hypophyseal portal and peripheral blood.","volume":"138","year":"1997","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R9","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1159\/000126520","article-title":"Effect of endotoxin on pituitary hormone secretion in sheep.","volume":"58","year":"1993","journal-title":"Neuroendocrinology"},{"key":"key\n\t\t\t\t20170224180721_R10","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1210\/endo.130.6.1597143","article-title":"Roles of interleukin-1\u03b1 and\u22121\u03b2 in endotoxin-induced suppression of plasma gonadotropin levels in rats.","volume":"130","year":"1992","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0006-8993(93)91637-8","article-title":"Mode of action of interleukin-1 suppression of pituitary LH release in castrated male rats.","volume":"612","year":"1993","journal-title":"Brain Res"},{"key":"key\n\t\t\t\t20170224180721_R12","first-page":"169","article-title":"Opioid peptides involvement in endotoxin-induced suppression of LH secretion in ovariectomized Holstein heifers.","volume":"1","year":"1995","journal-title":"Reprod Toxicol"},{"key":"key\n\t\t\t\t20170224180721_R13","doi-asserted-by":"crossref","first-page":"2077","DOI":"10.1210\/endo-128-4-2077","article-title":"An inhibitory effect of interleukin-1\u03b1 on basal gonadotropin release in the ovariectomized rhesus monkey: reversal by a corticotropin-releasing factor antagonist.","volume":"128","year":"1991","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R14","first-page":"659","volume-title":"The Physiology of Reproduction, vol.","year":"1994"},{"key":"key\n\t\t\t\t20170224180721_R15","first-page":"119","article-title":"Gonadotropic control of follicular development and function during the oestrous cycle of the ewe.","volume":"30","year":"1981","journal-title":"J Reprod Fertil Suppl"},{"key":"key\n\t\t\t\t20170224180721_R16","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1677\/joe.0.1260377","article-title":"The effect of a potent gonadotrophin-releasing hormone antagonist on ovarian secretion of oestradiol, inhibin and androstenedione and the concentration of LH and FSH during the follicular phase of the sheep oestrous cycle.","volume":"126","year":"1990","journal-title":"J Endocrinol"},{"key":"key\n\t\t\t\t20170224180721_R17","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0739-7240(97)00059-3","article-title":"Characterization of endocrine events during the periestrous period in sheep after estrous synchronization with controlled internal drug release (CIDR) device.","volume":"15","year":"1998","journal-title":"Domest Anim Endocrinol"},{"key":"key\n\t\t\t\t20170224180721_R18","first-page":"6","article-title":"How does melatonin code for day length in the ewe: duration of nocturnal melatonin release or coincidence of melatonin with a light-entrained sensitive period?","volume":"39","year":"1988","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180721_R19","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1210\/endo-101-3-807","article-title":"A new concept for control of the estrous cycle of the ewe based on the temporal relationships between luteinizing hormone, estradiol and progesterone in peripheral serum and evidence that progesterone inhibits tonic LH secretion.","volume":"101","year":"1977","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R20","first-page":"299","volume-title":"Gonadotropins","year":"1968"},{"key":"key\n\t\t\t\t20170224180721_R21","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1210\/endo-84-5-1166","article-title":"Radioimmunoassay for bovine and ovine luteinizing hormone.","volume":"84","year":"1969","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R22","doi-asserted-by":"crossref","first-page":"1806","DOI":"10.1210\/endo.134.4.8137746","article-title":"Central regulation of pulsatile GnRH secretion by estradiol during the period leading up to the preovulatory GnRH surge in the ewe.","volume":"134","year":"1994","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R23","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1159\/000127011","article-title":"Evidence for short or ultrashort loop negative feedback of gonadotropin-releasing hormone secretion.","volume":"62","year":"1995","journal-title":"Neuroendocrinology"},{"key":"key\n\t\t\t\t20170224180721_R24","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/0010-4809(72)90082-1","article-title":"Computer program sequence for analysis and summary of radioimmunoassay data.","volume":"5","year":"1972","journal-title":"Comput Biomed Res"},{"key":"key\n\t\t\t\t20170224180721_R25","first-page":"E486","article-title":"Cluster analysis: a simple, versatile and robust algorithm for endocrine pulse detection.","volume":"250","year":"1986","journal-title":"Am J Physiol"},{"key":"key\n\t\t\t\t20170224180721_R26","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1095\/biolreprod23.2.404","article-title":"Importance of estradiol and progesterone in regulating LH secretion and estrous behavior during the sheep estrous cycle.","volume":"23","year":"1980","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180721_R27","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1210\/endo-113-4-1333","article-title":"A role for estradiol in enhancing luteinizing hormone pulse frequency during the follicular phase of the estrous cycle of sheep.","volume":"113","year":"1983","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R28","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0306-4522(97)00350-3","article-title":"Time course and localization patterns of interleukin-1\u03b2 messenger RNA expression in brain and pituitary after peripheral administration of lipopolysaccharide.","volume":"83","year":"1998","journal-title":"Neuroscience"},{"key":"key\n\t\t\t\t20170224180721_R29","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1210\/endo-124-5-2105","article-title":"In the rat, interleukin-1\u03b1 acts at the level of the brain and the gonads to interfere with gonadotropin and sex steroid secretion.","volume":"124","year":"1989","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R30","first-page":"503","article-title":"Effects of lipopolysaccharide on ovarian function in the pregnant mare serum gonadotropin-treated immature rat.","volume":"1","year":"1993","journal-title":"Endocr J"},{"key":"key\n\t\t\t\t20170224180721_R31","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1095\/biolreprod54.6.1390","article-title":"Lipopolysaccharide inhibits in vitro luteinizing hormone-stimulated rat ovarian granulosa cell estradiol but not progesterone secretion.","volume":"54","year":"1996","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180721_R32","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1210\/endo-126-4-2145","article-title":"Interleukin-1 inhibits the ovarian steroid-induced luteinizing hormone surge and release of hypothalamic luteinizing hormone-releasing hormone in rats.","volume":"126","year":"1990","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R33","doi-asserted-by":"crossref","first-page":"2471","DOI":"10.1210\/endo.140.6.6739","article-title":"Endotoxin disrupts the estradiol-induced LH surge: interference with estradiol signal reading not surge release.","volume":"140","year":"1999","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R34","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/0378-1135(90)90033-R","article-title":"Effects of endotoxin infusion on circulating levels of eicosanoids, progesterone, cortisol, glucose and lactic acid, and abortion in pregnant cows.","volume":"21","year":"1990","journal-title":"Vet Microbiol"},{"key":"key\n\t\t\t\t20170224180721_R35","first-page":"170","article-title":"Cortisol blocks or delays the preovulatory surge of LH.","volume":"26","year":"1997","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180721_R36","first-page":"260","article-title":"Influence of the hypothalamic-pituitary-adrenal axis on the menstrual cycle and the pituitary responsiveness to estradiol in the female rhesus monkey (Macaca mulatta).","volume":"42","year":"1990","journal-title":"Biol Reprod"},{"key":"key\n\t\t\t\t20170224180721_R37","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1210\/endo-105-2-421","article-title":"Control of the preovulatory endocrine events in the ewe: interrelationship of estradiol, progesterone, and luteinizing hormone.","volume":"105","year":"1979","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R38","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1210\/endo.135.5.7956932","article-title":"Stimulatory effects of interleukin-induced activation of the hypothalamo-pituitary-adrenal axis on gonadotropin secretion in ovariectomized monkeys replaced with estradiol.","volume":"135","year":"1994","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R39","first-page":"2136","article-title":"Interleukin-1 stimulates luteinizing hormone release during the midfollicular phase in the rhesus monkey: a novel way in which stress may influence the menstrual cycle.","volume":"81","year":"1996","journal-title":"Endocrinology"},{"key":"key\n\t\t\t\t20170224180721_R40","first-page":"607","volume-title":"The Ovary.","year":"1993"}],"container-title":["Biology of Reproduction"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/biolreprod\/article-pdf\/62\/1\/45\/10592087\/biolreprod0045.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,4,3]],"date-time":"2019-04-03T18:03:54Z","timestamp":1554314634000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/biolreprod\/article-lookup\/doi\/10.1095\/biolreprod62.1.45"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,1,1]]},"references-count":40,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,1,1]]}},"URL":"https:\/\/doi.org\/10.1095\/biolreprod62.1.45","relation":{},"ISSN":["0006-3363","1529-7268"],"issn-type":[{"value":"0006-3363","type":"print"},{"value":"1529-7268","type":"electronic"}],"subject":[],"published":{"date-parts":[[2000,1,1]]}}}