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Due to reports of some nonspecific actions of 2\u2010APB, and the fact that its principal antagonistic effect is on Ca\n                    <jats:sup>2+<\/jats:sup>\n                    entry rather than Ca\n                    <jats:sup>2+<\/jats:sup>\n                    release, this compound may not have the utility first suggested. However, 2\u2010APB has thrown up some interesting results, particularly with respect to store\u2010operated Ca\n                    <jats:sup>2+<\/jats:sup>\n                    entry in nonexcitable cells. These data indicate that although it must be used with caution, 2\u2010APB can be useful in probing certain aspects of Ca\n                    <jats:sup>2+<\/jats:sup>\n                    signaling.\u2014Bootman, M. D., Collins, T. J., Mackenzie, L., Roderick, H. L., Berridge, M. J., Peppiatt, C. M. 2\u2010Aminoethoxydiphenyl borate (2\u2010APB) is a reliable blocker of store\u2010operated Ca\n                    <jats:sup>2+<\/jats:sup>\n                    entry but an inconsistent inhibitor of InsP\n                    <jats:sub>3<\/jats:sub>\n                    \u2010induced Ca\n                    <jats:sup>2+<\/jats:sup>\n                    release.\n                    <jats:italic>FASEB J<\/jats:italic>\n                    . 16, 1145\u20131150 (2002)\n                  <\/jats:p>","DOI":"10.1096\/fj.02-0037rev","type":"journal-article","created":{"date-parts":[[2002,9,30]],"date-time":"2002-09-30T13:43:21Z","timestamp":1033393401000},"page":"1145-1150","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":609,"title":["2\u2010Aminoethoxydiphenyl borate (2\u2010APB) is a reliable blocker of store\u2010operated Ca\n                    <sup>2+<\/sup>\n                    entry but an inconsistent inhibitor of InsP\n                    <sub>3<\/sub>\n                    \u2010induced Ca\n                    <sup>2+<\/sup>\n                    release"],"prefix":"10.1096","volume":"16","author":[{"given":"Martin D.","family":"Bootman","sequence":"first","affiliation":[{"name":"Laboratory of Molecular Signalling The Babraham Institute  Babraham Cambridge CB2 4AT UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tony J.","family":"Collins","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Signalling The Babraham Institute  Babraham Cambridge CB2 4AT UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Mackenzie","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular Signalling The Babraham Institute  Babraham Cambridge CB2 4AT UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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