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The information on monkey genomes is still limited and no versatile gene expression screening tool is available. We tested human whole genome microarrays for cross\u2010species reactivity with AGM transcripts using both long oligonucleotide arrays (60\u2010mer probes) and short oligonucleotide arrays (25\u2010mer). Using the long oligonucleotide arrays, we detected 4\u2010fold more AGM transcripts than with the short oligonucleotide technology. The number of detected transcripts was comparable to that detected using human RNA, with 87% of the detected genes being shared between both species. The specificity of the signals obtained with the long oligonucleotide arrays was determined by analyzing the transcriptome of concanava\u2010lin A\u2010activated CD4\n                    <jats:sup>+<\/jats:sup>\n                    T cells\n                    <jats:italic>vs.<\/jats:italic>\n                    nonactivated T cells of two monkey species AGM and macaque. For both species, the genes showing the most significant changes in expression, such as IL\u20102R, were those known to be regulated in human CD4\n                    <jats:sup>+<\/jats:sup>\n                    T cell activation. Finally, tissue specificity of the signals was established by comparing the transcription profiles of AGM brain and tonsil cells. In conclusion, the ABI human microarray platform provides a highly valuable tool for the assessment of AGM gene expression profiles.\u2014Jacquelin B., Mayau, V., Brysbaert, G., Regnault, B., Diop, O. M., Arenzana\u2010Seisdedos, F., Rogge, L., Copp\u00e9e J\u2010Y., Barr\u00e9\u2010Sinoussi F., Benecke, A., M\u00fcller\u2010Trutwin M. C. Long oligonucleotide microarrays for African green monkey gene expression profile analysis.\n                    <jats:italic>FASEB J.<\/jats:italic>\n                    21, 3262\u20133271 (2007)\n                  <\/jats:p>","DOI":"10.1096\/fj.07-8271com","type":"journal-article","created":{"date-parts":[[2007,5,16]],"date-time":"2007-05-16T21:10:58Z","timestamp":1179349858000},"page":"3262-3271","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Long oligonucleotide microarrays for African green monkey gene expression profile analysis"],"prefix":"10.1096","volume":"21","author":[{"given":"B\u00e9atrice","family":"Jacquelin","sequence":"first","affiliation":[{"name":"Unit\u00e9de R\u00e9gulation des Infections R\u00e9trovirales Institut Pasteur Paris France"},{"name":"Plateforme Puces \u00e0 ADN\u2010Genopole Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronique","family":"Mayau","sequence":"additional","affiliation":[{"name":"Unit\u00e9de R\u00e9gulation des Infections R\u00e9trovirales Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Brysbaert","sequence":"additional","affiliation":[{"name":"Institut de Recherche Interdisciplinaire\u2010CNRS and Institut des Hautes \u00c9tudes Scientifiques Bures sur Yvette France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e9atrice","family":"Regnault","sequence":"additional","affiliation":[{"name":"Plateforme Puces \u00e0 ADN\u2010Genopole Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ousmane M.","family":"Diop","sequence":"additional","affiliation":[{"name":"Laboratoire de R\u00e9trovirologie Institut Pasteur Dakar Senegal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Arenzana\u2010Seisdedos","sequence":"additional","affiliation":[{"name":"Laboratoire de Pathologie Virale Mol\u00e9culaire Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Rogge","sequence":"additional","affiliation":[{"name":"Groupe \u00e0 5 ans Immunor\u00e9gulation Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Yves","family":"Copp\u00e9e","sequence":"additional","affiliation":[{"name":"Plateforme Puces \u00e0 ADN\u2010Genopole Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7oise","family":"Barr\u00e9\u2010Sinoussi","sequence":"additional","affiliation":[{"name":"Unit\u00e9de R\u00e9gulation des Infections R\u00e9trovirales Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arndt","family":"Benecke","sequence":"additional","affiliation":[{"name":"Institut de Recherche Interdisciplinaire\u2010CNRS and Institut des Hautes \u00c9tudes Scientifiques Bures sur Yvette France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michaela C.","family":"M\u00fcller\u2010Trutwin","sequence":"additional","affiliation":[{"name":"Unit\u00e9de R\u00e9gulation des Infections R\u00e9trovirales Institut Pasteur Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,5,16]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/ilar.42.2.74"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6446(02)02578-3"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1217"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth0605-477a"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth756"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-6-63"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1239"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-6-160"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0684.2006.00180.x"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2005-6-7-r60"},{"key":"e_1_2_5_12_1","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1096\/fj.02-0681fje","article-title":"Microarray analysis of nonhuman primates: validation of experimental models in neurological disorders","volume":"17","author":"Marvanova M.","year":"2003","journal-title":"FASEB J."},{"key":"e_1_2_5_13_1","article-title":"Analysis of result variability from high-density oligonucleotide arrays comparing same-species and cross-species hybridizations","volume":"33","author":"Chismar J. 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