{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T15:54:31Z","timestamp":1769270071118,"version":"3.49.0"},"reference-count":115,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2009,7,29]],"date-time":"2009-07-29T00:00:00Z","timestamp":1248825600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100010329","name":"University of Bradford","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010329","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["faseb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The FASEB Journal"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>\n                    Vitiligo is characterized by a patchy loss of inherited skin color affecting \u03030.5% of individuals of all races. Despite the absence of the protecting pigment and the overwhelming evidence for hydrogen peroxide (H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    )\u2010induced oxidative stress in the entire epidermis of these patients, there is neither increased photodamage\/skin aging nor a higher incidence for sun\u2010induced nonmelanoma skin cancer. Here we demonstrate for the first time increased DNA damage\n                    <jats:italic>via<\/jats:italic>\n                    8\u2010oxoguanine in the skin and plasma in association with epidermal up\u2010regulated phosphorylated\/acetylated p53 and high levels of the p53 antagonist p76\n                    <jats:sup>MDM2<\/jats:sup>\n                    . Shortpatch base\u2010excision repair\n                    <jats:italic>via<\/jats:italic>\n                    hOggl, APE1, and polymerase\u03b2 DNA repair is up\u2010regulated. Overexpression of Bcl\u20102 and low caspase 3 and cytochrome\n                    <jats:italic>c<\/jats:italic>\n                    levels argue against increased apoptosis in this disease. Moreover, we show the presence of high epidermal peroxynitrite (ONOO\n                    <jats:sup>\u2212<\/jats:sup>\n                    ) levels\n                    <jats:italic>via<\/jats:italic>\n                    nitrotyrosine together with high nitrated p53 levels. We demonstrate by EMSA that nitration of p53 by ONOO\n                    <jats:sup>\u2212<\/jats:sup>\n                    (300\u00d710\n                    <jats:sup>\u22126<\/jats:sup>\n                    M) abrogates DNA binding, while H\n                    <jats:sub>2<\/jats:sub>\n                    O\n                    <jats:sub>2<\/jats:sub>\n                    \u2010oxidized p53 (10\n                    <jats:sup>\u22123<\/jats:sup>\n                    M) enhances DNA binding capacity and prevents ONOO\n                    <jats:sup>\u2212<\/jats:sup>\n                    induced abrogation of DNA binding. Taken together, we add a novel reactive oxygen species to the list of oxidative stress inducers in vitiligo. Moreover, we pro\n                    <jats:sub>!<\/jats:sub>\n                    pose up\u2010regulated wild\u2010type p53 together with p76\n                    <jats:sup>MDM2<\/jats:sup>\n                    as major players in the control of DNA damage\/repair and prevention of photodamage and nonmelanoma skin cancer in vitiligo.\u2014Salem, M. M. A. E. L., Shalbaf, M., Gibbons, N. C. J., Chavan, B., Thornton, J. M., Schallreuter, K. U. Enhanced DNA binding capacity on up\u2010regulated epidermal wild\u2010type p53 in vitiligo by H\n                    <jats:sub>!<\/jats:sub>\n                    O\n                    <jats:sub>!<\/jats:sub>\n                    \u2010mediated oxidation: a possible repair mechanism for DNA damage.\n                    <jats:italic>FASEB J.<\/jats:italic>\n                    23, 3790\u20133807 (2009).\n                    <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/www.fasebj.org\">www.fasebj.org<\/jats:ext-link>\n                  <\/jats:p>","DOI":"10.1096\/fj.09-132621","type":"journal-article","created":{"date-parts":[[2009,7,29]],"date-time":"2009-07-29T21:47:57Z","timestamp":1248904077000},"page":"3790-3807","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":64,"title":["Enhanced DNA binding capacity on up\u2010regulated epidermal wild\u2010type p53 in vitiligo by H\n                    <sub>2<\/sub>\n                    O\n                    <sub>2<\/sub>\n                    \u2010mediated oxidation: a possible repair mechanism for DNA damage"],"prefix":"10.1096","volume":"23","author":[{"given":"Mohamed M. A. E. L.","family":"Salem","sequence":"first","affiliation":[{"name":"Clinical and Experimental Dermatology Department of Biomedical Sciences\/Centre for Skin Sciences School of Life Sciences University of Bradford Bradford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Shalbaf","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Dermatology Department of Biomedical Sciences\/Centre for Skin Sciences School of Life Sciences University of Bradford Bradford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas C. J.","family":"Gibbons","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Dermatology Department of Biomedical Sciences\/Centre for Skin Sciences School of Life Sciences University of Bradford Bradford UK"},{"name":"University of Bradford Bradford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhaven","family":"Chavan","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Dermatology Department of Biomedical Sciences\/Centre for Skin Sciences School of Life Sciences University of Bradford Bradford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. M.","family":"Thornton","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Dermatology Department of Biomedical Sciences\/Centre for Skin Sciences School of Life Sciences University of Bradford Bradford UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin U.","family":"Schallreuter","sequence":"additional","affiliation":[{"name":"Clinical and Experimental Dermatology Department of Biomedical Sciences\/Centre for Skin Sciences School of Life Sciences University of Bradford Bradford UK"},{"name":"Institute for Pigmentary Disorders in association with E. M. Arndt University Greifswald Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2009,7,29]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2008.00697.x"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2007.00666.x"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jidsp.5640189"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.0022-202X.2004.22230.x"},{"issue":"3","key":"e_1_2_5_6_1","article-title":"Functional and structural index ofcellular impairment during vitiligo","volume":"126","author":"Dell'Anna M. L.","year":"2006","journal-title":"J. Invest. Dermatol."},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2003.00087.x"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700257"},{"key":"e_1_2_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12492612"},{"key":"e_1_2_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2004.01.082"},{"key":"e_1_2_5_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.150.3692.72"},{"key":"e_1_2_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700612"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2002.00057.x"},{"key":"e_1_2_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2006.05.063"},{"key":"e_1_2_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.0906-6705.2006.00423.x"},{"key":"e_1_2_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.2008.00699.x"},{"key":"e_1_2_5_17_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00044.2003"},{"key":"e_1_2_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2007.10.007"},{"key":"e_1_2_5_19_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.08-125435"},{"key":"e_1_2_5_20_1","doi-asserted-by":"publisher","DOI":"10.1159\/000057881"},{"key":"e_1_2_5_21_1","doi-asserted-by":"publisher","DOI":"10.1159\/000249197"},{"key":"e_1_2_5_22_1","article-title":"PUVA for vitiligo and skin cancer","volume":"22","author":"Westerhof W.","year":"1997","journal-title":"Clin. Exp. Dermatol."},{"key":"e_1_2_5_23_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0625.2003.00084.x"},{"key":"e_1_2_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2000.03712.x"},{"key":"e_1_2_5_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.1997.tb00461.x"},{"key":"e_1_2_5_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/08916930108994127"},{"key":"e_1_2_5_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9896(2000)9999:9999<::AID-PATH659>3.0.CO;2-D"},{"key":"e_1_2_5_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1203013"},{"key":"e_1_2_5_29_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.8.5733"},{"key":"e_1_2_5_30_1","doi-asserted-by":"publisher","DOI":"10.1096\/fasebj.11.7.9212076"},{"key":"e_1_2_5_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-007-6362-1"},{"key":"e_1_2_5_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb04067.x"},{"key":"e_1_2_5_33_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670060015008"},{"key":"e_1_2_5_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.1968.15"},{"key":"e_1_2_5_35_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.1.06275"},{"key":"e_1_2_5_36_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/7.6.1513"},{"key":"e_1_2_5_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/9.13.2989"},{"key":"e_1_2_5_38_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2001.00220.x"},{"key":"e_1_2_5_39_1","volume-title":"Ph.D. thesis","author":"Salem M. M. A. E.","year":"2009"},{"key":"e_1_2_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90562-Q"},{"key":"e_1_2_5_41_1","volume-title":"Ph.D. thesis","author":"Oberprieler N. G.","year":"2007"},{"key":"e_1_2_5_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/35002510"},{"key":"e_1_2_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-483X(03)00150-1"},{"key":"e_1_2_5_44_1","first-page":"1136","article-title":"Oxidative stress in pterygium: relationship between p53 and 8-hydroxydeoxyguanosine","volume":"12","author":"Perra M. T.","year":"2006","journal-title":"Mol. Vis."},{"key":"e_1_2_5_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(02)00818-3"},{"key":"e_1_2_5_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/ja962255b"},{"key":"e_1_2_5_47_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/12.4.2137"},{"key":"e_1_2_5_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/15287399309531806"},{"key":"e_1_2_5_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccn.2003.09.010"},{"key":"e_1_2_5_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05978"},{"key":"e_1_2_5_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/1011-1344(93)87101-R"},{"key":"e_1_2_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-9084(99)80039-X"},{"key":"e_1_2_5_53_1","doi-asserted-by":"crossref","first-page":"5197","DOI":"10.1073\/pnas.93.11.5197","article-title":"Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine","volume":"93","author":"der Kemp P. A.","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"e_1_2_5_54_1","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.2000.1773"},{"key":"e_1_2_5_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrfmmm.2003.07.004"},{"key":"e_1_2_5_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0921-8777(01)00078-7"},{"key":"e_1_2_5_57_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.21.15230"},{"key":"e_1_2_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0969-2126(97)00303-1"},{"key":"e_1_2_5_59_1","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2867-7-15"},{"key":"e_1_2_5_60_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.24.16979"},{"key":"e_1_2_5_61_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1062238"},{"key":"e_1_2_5_62_1","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1016\/S1389-1723(01)80324-8","article-title":"Radiation-inducible TNF-\u03b1lpha gene expression under stress-inducible promoter gadd 153 for cancer therapy","volume":"92","author":"Ito A.","year":"2001","journal-title":"J. Biosci. Bioeng."},{"key":"e_1_2_5_63_1","doi-asserted-by":"publisher","DOI":"10.1038\/35018127"},{"key":"e_1_2_5_64_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi970759w"},{"key":"e_1_2_5_65_1","first-page":"1169","article-title":"WAF1\/CIP1 is induced in p53-mediated G1 arrest and apoptosis","volume":"54","author":"El-Deiry W. S.","year":"1994","journal-title":"Cancer Res."},{"key":"e_1_2_5_66_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.13.2.152"},{"key":"e_1_2_5_67_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8266092"},{"key":"e_1_2_5_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(94)90519-3"},{"key":"e_1_2_5_69_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.7.3706"},{"key":"e_1_2_5_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1992.tb38657.x"},{"key":"e_1_2_5_71_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2002.01781.x"},{"key":"e_1_2_5_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mrfmmm.2004.06.055"},{"key":"e_1_2_5_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(99)00291-9"},{"key":"e_1_2_5_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90500-P"},{"key":"e_1_2_5_75_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.16.7491"},{"key":"e_1_2_5_76_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.091100298"},{"key":"e_1_2_5_77_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.7997877"},{"key":"e_1_2_5_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(92)90586-2"},{"key":"e_1_2_5_79_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.8091232"},{"key":"e_1_2_5_80_1","doi-asserted-by":"publisher","DOI":"10.2165\/00128071-200203050-00001"},{"key":"e_1_2_5_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2007.03.009"},{"key":"e_1_2_5_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2007.07.012"},{"key":"e_1_2_5_83_1","first-page":"9","article-title":"Minocycline protects melanocytes against H2O2-induced cell death via JNK and p38 MAPK pathways","volume":"22","author":"Song X.","year":"2008","journal-title":"Int. J. Mol. Med."},{"key":"e_1_2_5_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(94)01161-3"},{"key":"e_1_2_5_85_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3190299"},{"key":"e_1_2_5_86_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.6.2442"},{"key":"e_1_2_5_87_1","first-page":"3365","article-title":"Nitric oxide induces conformational and functional modifications of wildtype p53 tumor suppressor protein","volume":"57","author":"Calmels S.","year":"1997","journal-title":"Cancer Res."},{"key":"e_1_2_5_88_1","doi-asserted-by":"publisher","DOI":"10.1006\/abbi.2001.2540"},{"key":"e_1_2_5_89_1","first-page":"8670","article-title":"Inactivation of wild-type p53 protein function by reactive oxygen and nitrogen species in malignant glioma cells","volume":"63","author":"Cobbs C. S.","year":"2003","journal-title":"Cancer Res."},{"key":"e_1_2_5_90_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.3263703"},{"key":"e_1_2_5_91_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0749.2002.1o049.x"},{"key":"e_1_2_5_92_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3000531"},{"key":"e_1_2_5_93_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0560.1983.tb00328.x"},{"key":"e_1_2_5_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12500086"},{"key":"e_1_2_5_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12335801"},{"key":"e_1_2_5_96_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1996.271.5.C1424"},{"key":"e_1_2_5_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(96)69020-X"},{"key":"e_1_2_5_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5849(01)00633-5"},{"key":"e_1_2_5_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700021"},{"key":"e_1_2_5_100_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700051"},{"key":"e_1_2_5_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-5793(97)00748-5"},{"key":"e_1_2_5_102_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.jid.5700268"},{"key":"e_1_2_5_103_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.2003"},{"key":"e_1_2_5_104_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.12.19.2973"},{"key":"e_1_2_5_105_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/20.6.1331"},{"key":"e_1_2_5_106_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.2001.02225.x"},{"key":"e_1_2_5_107_1","doi-asserted-by":"publisher","DOI":"10.1038\/358080a0"},{"key":"e_1_2_5_108_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi00160a004"},{"key":"e_1_2_5_109_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6603(01)68086-3"},{"key":"e_1_2_5_110_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.24.12754"},{"key":"e_1_2_5_111_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-3233(04)69001-2"},{"key":"e_1_2_5_112_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.14.9.6187"},{"key":"e_1_2_5_113_1","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.11.3341"},{"key":"e_1_2_5_114_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.271.16.9573"},{"key":"e_1_2_5_115_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi011117i"},{"key":"e_1_2_5_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1546"}],"container-title":["The FASEB Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1096\/fj.09-132621","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1096\/fj.09-132621","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/pdf\/10.1096\/fj.09-132621","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T22:43:26Z","timestamp":1761691406000},"score":1,"resource":{"primary":{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/10.1096\/fj.09-132621"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,7,29]]},"references-count":115,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2009,11]]}},"alternative-id":["10.1096\/fj.09-132621"],"URL":"https:\/\/doi.org\/10.1096\/fj.09-132621","archive":["Portico"],"relation":{},"ISSN":["0892-6638","1530-6860"],"issn-type":[{"value":"0892-6638","type":"print"},{"value":"1530-6860","type":"electronic"}],"subject":[],"published":{"date-parts":[[2009,7,29]]},"assertion":[{"value":"2009-05-13","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-06-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2009-07-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}