{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T07:45:21Z","timestamp":1791791121677,"version":"4.3.4"},"reference-count":175,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:00:00Z","timestamp":1789171200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T00:00:00Z","timestamp":1789171200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M754280"],"award-info":[{"award-number":["2024M754280"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["faseb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The FASEB Journal"],"published-print":{"date-parts":[[2026,9,30]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:p>Traumatic brain injury (TBI) initiates a complex secondary injury cascade that significantly contributes to long\u2010term neurological deficits, with post\u2010translational modifications (PTMs) emerging as pivotal molecular regulators of this process. Unlike primary mechanical damage, secondary injury evolves over hours to years and involves intricate proteomic alterations that changes in gene expression alone cannot fully explain. PTMs\u2014including phosphorylation, ubiquitination, acetylation, SUMOylation, glycosylation, and emerging modifications such as succinylation, lactylation, and nitrosylation\u2014serve as dynamic molecular switches that fine\u2010tune protein function, stability, localization, and interactions in response to TBI\u2010induced stressors. These modifications play dual roles: they can either promote neuroprotection and recovery or drive pathological processes such as neuronal cell death (via apoptosis, necroptosis, and ferroptosis), neuroinflammation through glial activation and inflammasome signaling, blood\u2013brain barrier disruption, mitochondrial dysfunction, and impaired synaptic plasticity. Critically, extensive crosstalk exists among different PTM pathways\u2014such as the interplay between phosphorylation and ubiquitination in protein degradation or the competitive balance between acetylation and SUMOylation\u2014that collectively shape cellular fate after injury. This nuanced regulatory network presents both challenges and opportunities for therapeutic intervention. Targeting PTM\u2010related enzymes, including kinases, phosphatases, E3 ligases, and histone deacetylases, has shown promise in preclinical models, while novel strategies like Proteolysis\u2010Targeting Chimeras (PROTACs) and repurposed drugs (e.g., metformin, resveratrol) offer innovative avenues for modulating the PTM landscape. Advances in high\u2010throughput proteomics and mass spectrometry are enabling the mapping of TBI\u2010specific PTM signatures across spatiotemporal phases, facilitating the identification of pro\u2010survival versus pro\u2010death modification thresholds. Despite hurdles in clinical translation\u2014such as blood\u2013brain barrier penetration and off\u2010target effects\u2014the growing understanding of PTM dynamics underscores their potential as both biomarkers and therapeutic targets. Future TBI management may thus rely on precision medicine approaches that integrate multi\u2010PTM profiling to guide combination therapies aimed at tipping the balance toward neural repair and functional recovery.<\/jats:p>","DOI":"10.1096\/fj.202602218rr","type":"journal-article","created":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T17:20:33Z","timestamp":1789233633000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Post\u2010Translational Modifications in Traumatic Brain Injury: Decoding the Proteomic Landscape and Molecular Mechanisms of Secondary Injury"],"prefix":"10.1096","volume":"40","author":[{"given":"PeiPei","family":"Shen","sequence":"first","affiliation":[{"name":"Department of Anesthesiology Jinling Hospital, Jinling School of Clinical Medicine, Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liping","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Jinling Hospital, Jinling School of Clinical Medicine, Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0191-6769","authenticated-orcid":false,"given":"Zhonghua","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Jinling Hospital, Jinling School of Clinical Medicine, Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Zong","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Jinling Hospital, Jinling School of Clinical Medicine, Nanjing University  Nanjing China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,9,12]]},"reference":[{"key":"e_1_2_15_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amepre.2025.01.001"},{"key":"e_1_2_15_3_1","doi-asserted-by":"publisher","DOI":"10.1159\/000547563"},{"key":"e_1_2_15_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01870-3"},{"issue":"10","key":"e_1_2_15_5_1","article-title":"Revisiting Traumatic Brain Injury: From Molecular Mechanisms to Therapeutic Interventions","volume":"8","author":"Jarrahi A.","year":"2020","journal-title":"Biomedicine"},{"key":"e_1_2_15_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-025-04449-0"},{"key":"e_1_2_15_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102489"},{"key":"e_1_2_15_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom14010118"},{"key":"e_1_2_15_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2026.115652"},{"key":"e_1_2_15_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-021-03503-x"},{"key":"e_1_2_15_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2025.106094"},{"key":"e_1_2_15_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-025-01923-7"},{"key":"e_1_2_15_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2025.02.005"},{"key":"e_1_2_15_14_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-025-03817-2"},{"key":"e_1_2_15_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-025-08706-6"},{"key":"e_1_2_15_16_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2025.1570596"},{"key":"e_1_2_15_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-024-04316-4"},{"key":"e_1_2_15_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms262412158"},{"key":"e_1_2_15_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics14010152"},{"key":"e_1_2_15_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells14231878"},{"key":"e_1_2_15_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.70568"},{"key":"e_1_2_15_22_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-025-00478-5"},{"key":"e_1_2_15_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-025-02123-3"},{"key":"e_1_2_15_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12028-025-02293-2"},{"key":"e_1_2_15_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-025-04519-3"},{"key":"e_1_2_15_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-025-00842-z"},{"key":"e_1_2_15_27_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2022.0219"},{"key":"e_1_2_15_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14954"},{"key":"e_1_2_15_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-024-06515-x"},{"key":"e_1_2_15_30_1","doi-asserted-by":"publisher","DOI":"10.1089\/neur.2021.0001"},{"key":"e_1_2_15_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2026.e00846"},{"key":"e_1_2_15_32_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.880267"},{"key":"e_1_2_15_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2026.116613"},{"key":"e_1_2_15_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2026.121582"},{"key":"e_1_2_15_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2024.04.031"},{"key":"e_1_2_15_36_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1125662"},{"key":"e_1_2_15_37_1","doi-asserted-by":"publisher","DOI":"10.1515\/tnsci-2022-0272"},{"key":"e_1_2_15_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/medicina62020362"},{"key":"e_1_2_15_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043120"},{"key":"e_1_2_15_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12915-023-01800-1"},{"key":"e_1_2_15_41_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-023-01056-w"},{"key":"e_1_2_15_42_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12883-025-04303-4"},{"key":"e_1_2_15_43_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-05360-z"},{"key":"e_1_2_15_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25052880"},{"key":"e_1_2_15_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25042372"},{"key":"e_1_2_15_46_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26199604"},{"key":"e_1_2_15_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-025-05258-1"},{"key":"e_1_2_15_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(22)00309-X"},{"key":"e_1_2_15_49_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000214674"},{"key":"e_1_2_15_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2025.2546148"},{"key":"e_1_2_15_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2024.01.084"},{"key":"e_1_2_15_52_1","doi-asserted-by":"publisher","DOI":"10.1177\/11772719221105145"},{"key":"e_1_2_15_53_1","doi-asserted-by":"publisher","DOI":"10.31083\/FBL38904"},{"key":"e_1_2_15_54_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms232113000"},{"key":"e_1_2_15_55_1","doi-asserted-by":"publisher","DOI":"10.4103\/NRR.NRR-D-24-01398"},{"key":"e_1_2_15_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000002420"},{"key":"e_1_2_15_57_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-026-02257-3"},{"key":"e_1_2_15_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2025.115147"},{"key":"e_1_2_15_59_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2021.658852"},{"key":"e_1_2_15_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-021-01949-w"},{"key":"e_1_2_15_61_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26136456"},{"key":"e_1_2_15_62_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-026-05822-y"},{"key":"e_1_2_15_63_1","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.70729"},{"key":"e_1_2_15_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2025.06.020"},{"key":"e_1_2_15_65_1","doi-asserted-by":"publisher","DOI":"10.4103\/NRR.NRR-D-24-00890"},{"key":"e_1_2_15_66_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2024.1448570"},{"key":"e_1_2_15_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2025.115454"},{"key":"e_1_2_15_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2023.05.069"},{"key":"e_1_2_15_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2025.07.009"},{"key":"e_1_2_15_70_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-026-70304-7"},{"key":"e_1_2_15_71_1","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X231197173"},{"key":"e_1_2_15_72_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26115066"},{"key":"e_1_2_15_73_1","doi-asserted-by":"publisher","DOI":"10.1002\/iid3.70106"},{"issue":"8","key":"e_1_2_15_74_1","first-page":"1193","article-title":"SENP5 Deteriorates Traumatic Brain Injury via SUMO2\u2010Dependent Suppression of E2F1 SUMOylation","volume":"55","author":"Ding Y.","year":"2023","journal-title":"Acta Biochimica et Biophysica Sinica"},{"key":"e_1_2_15_75_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2024.2350669"},{"key":"e_1_2_15_76_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24469-y"},{"key":"e_1_2_15_77_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02563-2"},{"key":"e_1_2_15_78_1","doi-asserted-by":"publisher","DOI":"10.4103\/1673-5374.374654"},{"key":"e_1_2_15_79_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-025-02214-w"},{"key":"e_1_2_15_80_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-180177"},{"key":"e_1_2_15_81_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2022.892197"},{"key":"e_1_2_15_82_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-05539-4"},{"key":"e_1_2_15_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.115765"},{"key":"e_1_2_15_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2017.04.016"},{"key":"e_1_2_15_85_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40779-023-00482-8"},{"key":"e_1_2_15_86_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2025.106772"},{"key":"e_1_2_15_87_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellin.2023.100128"},{"key":"e_1_2_15_88_1","doi-asserted-by":"publisher","DOI":"10.1080\/10409238.2025.2574638"},{"key":"e_1_2_15_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41594-024-01294-7"},{"key":"e_1_2_15_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2025.110715"},{"key":"e_1_2_15_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-15608-y"},{"key":"e_1_2_15_92_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells13090734"},{"key":"e_1_2_15_93_1","doi-asserted-by":"publisher","DOI":"10.1093\/burnst\/tkad062"},{"key":"e_1_2_15_94_1","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000003032"},{"key":"e_1_2_15_95_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.5c10061"},{"key":"e_1_2_15_96_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox14060640"},{"key":"e_1_2_15_97_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.14565"},{"key":"e_1_2_15_98_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-17758-4"},{"key":"e_1_2_15_99_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurot.2025.e00708"},{"key":"e_1_2_15_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2024.10.013"},{"key":"e_1_2_15_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.niox.2024.11.005"},{"key":"e_1_2_15_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26189245"},{"key":"e_1_2_15_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2025.107200"},{"key":"e_1_2_15_104_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2024.2367923"},{"key":"e_1_2_15_105_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-04333-z"},{"key":"e_1_2_15_106_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-024-01515-y"},{"key":"e_1_2_15_107_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10142-025-01760-5"},{"key":"e_1_2_15_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ibneur.2025.10.017"},{"key":"e_1_2_15_109_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-025-03633-x"},{"key":"e_1_2_15_110_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2020.113524"},{"key":"e_1_2_15_111_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-025-03512-5"},{"key":"e_1_2_15_112_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.114930"},{"key":"e_1_2_15_113_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2023.0580"},{"key":"e_1_2_15_114_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2023.106550"},{"key":"e_1_2_15_115_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-025-02125-6"},{"key":"e_1_2_15_116_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1742-23.2024"},{"key":"e_1_2_15_117_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-025-00449-6"},{"issue":"2","key":"e_1_2_15_118_1","article-title":"The Imbalance of Astrocytic Mitochondrial Dynamics Following Blast\u2010Induced Traumatic Brain Injury","volume":"11","author":"Guilhaume\u2010Correa F.","year":"2023","journal-title":"Biomedicine"},{"key":"e_1_2_15_119_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2025.1697060"},{"key":"e_1_2_15_120_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abo6889"},{"key":"e_1_2_15_121_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-024-02810-1"},{"key":"e_1_2_15_122_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnsyn.2025.1534379"},{"key":"e_1_2_15_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2025.149647"},{"key":"e_1_2_15_124_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-025-05893-5"},{"key":"e_1_2_15_125_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2019.111547"},{"key":"e_1_2_15_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2021.12.002"},{"key":"e_1_2_15_127_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-025-10489-0"},{"key":"e_1_2_15_128_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2025.111739"},{"key":"e_1_2_15_129_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.70282"},{"key":"e_1_2_15_130_1","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/7879629"},{"key":"e_1_2_15_131_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-04711-0"},{"key":"e_1_2_15_132_1","doi-asserted-by":"publisher","DOI":"10.4103\/NRR.NRR-D-24-00113"},{"key":"e_1_2_15_133_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-05619-5"},{"key":"e_1_2_15_134_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaf750"},{"key":"e_1_2_15_135_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-0172-4"},{"key":"e_1_2_15_136_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-024-06748-w"},{"key":"e_1_2_15_137_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20225774"},{"key":"e_1_2_15_138_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci10070449"},{"key":"e_1_2_15_139_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2025.2471633"},{"key":"e_1_2_15_140_1","doi-asserted-by":"publisher","DOI":"10.1097\/JS9.0000000000003249"},{"key":"e_1_2_15_141_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2025.10.288"},{"key":"e_1_2_15_142_1","doi-asserted-by":"publisher","DOI":"10.1089\/neu.2021.0311"},{"key":"e_1_2_15_143_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.00401"},{"key":"e_1_2_15_144_1","doi-asserted-by":"publisher","DOI":"10.1080\/00207454.2024.2332959"},{"key":"e_1_2_15_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2025.118110"},{"key":"e_1_2_15_146_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-026-02518-9"},{"key":"e_1_2_15_147_1","doi-asserted-by":"publisher","DOI":"10.2174\/011570159X438970260115164001"},{"key":"e_1_2_15_148_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2026.115876"},{"key":"e_1_2_15_149_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-020-00594-3"},{"key":"e_1_2_15_150_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-019-09366-1"},{"key":"e_1_2_15_151_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2022.148109"},{"key":"e_1_2_15_152_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.15258"},{"key":"e_1_2_15_153_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0000000000001805"},{"key":"e_1_2_15_154_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12906-024-04639-3"},{"key":"e_1_2_15_155_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2024.1380353"},{"key":"e_1_2_15_156_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11306-022-01970-z"},{"key":"e_1_2_15_157_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2023.1239653"},{"key":"e_1_2_15_158_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-023-03281-3"},{"key":"e_1_2_15_159_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26136277"},{"key":"e_1_2_15_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.03.032"},{"key":"e_1_2_15_161_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-023-03379-8"},{"key":"e_1_2_15_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.13997"},{"issue":"4","key":"e_1_2_15_163_1","article-title":"Increases of Phosphorylated Tau (Ser202\/Thr205) in the Olfactory Regions Are Associated With Impaired EEG and Olfactory Behavior in Traumatic Brain Injury Mice","volume":"10","author":"Yoon Y.","year":"2022","journal-title":"Biomedicine"},{"key":"e_1_2_15_164_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12640-022-00495-6"},{"key":"e_1_2_15_165_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2023.04.014"},{"key":"e_1_2_15_166_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2023.149320"},{"key":"e_1_2_15_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2023.114352"},{"key":"e_1_2_15_168_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02651-3"},{"key":"e_1_2_15_169_1","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci15030236"},{"key":"e_1_2_15_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2025.01.021"},{"key":"e_1_2_15_171_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26030906"},{"key":"e_1_2_15_172_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02466-7"},{"key":"e_1_2_15_173_1","doi-asserted-by":"publisher","DOI":"10.5607\/en25020"},{"key":"e_1_2_15_174_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2019.11.001"},{"key":"e_1_2_15_175_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1606268"},{"key":"e_1_2_15_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105310"}],"container-title":["The FASEB Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/pdf\/10.1096\/fj.202602218RR","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/full-xml\/10.1096\/fj.202602218RR","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/pdf\/10.1096\/fj.202602218RR","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T06:52:32Z","timestamp":1791787952000},"score":1,"resource":{"primary":{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/10.1096\/fj.202602218RR"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,12]]},"references-count":175,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2026,9,30]]}},"alternative-id":["10.1096\/fj.202602218RR"],"URL":"https:\/\/doi.org\/10.1096\/fj.202602218rr","archive":["Portico"],"relation":{},"ISSN":["0892-6638","1530-6860"],"issn-type":[{"value":"0892-6638","type":"print"},{"value":"1530-6860","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,12]]},"assertion":[{"value":"2026-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e72307"}}