{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T21:15:15Z","timestamp":1791321315584,"version":"4.3.1"},"reference-count":0,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[1997,12,1]],"date-time":"1997-12-01T00:00:00Z","timestamp":880934400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["faseb.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The FASEB Journal"],"published-print":{"date-parts":[[1997,12]]},"abstract":"<jats:p>\n                    An astounding number of important regulatory and structural proteins are subject to modification by the attachment of ubiquitin or ubiquitin\u2010like proteins. This modification acts as a targeting signal, delivering the modified protein to different locations in the cell and modifying its activity, macromolecular interactions, or half\u2010life. Deubiquitination, or the removal of this modification, is being recognized as an important regulatory strategy. This reaction is catalyzed by processing proteases known as deubiquitinating enzymes (DUBs). More than 60 DUBs are already known, although little is known about their biological roles. This review concentrates on recent findings and new insights into this fascinating class of enzymes.\u2014Wilkinson, K. D. Regulation of ubiquitin\u2010dependent processes by deubiquitinating enzymes.\n                    <jats:italic>FASEB J.<\/jats:italic>\n                    11, 1245\u20131256 (1997)\n                  <\/jats:p>","DOI":"10.1096\/fasebj.11.14.9409543","type":"journal-article","created":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T06:05:22Z","timestamp":1516255522000},"page":"1245-1256","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":492,"title":["Regulation of ubiquitin\u2010dependent processes by deubiquitinating enzymes"],"prefix":"10.1096","volume":"11","author":[{"given":"Keith D.","family":"Wilkinson","sequence":"first","affiliation":[{"name":"Department of Biochemistry Emory University Atlanta Georgia 30322 USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1997,12]]},"container-title":["The FASEB Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1096\/fasebj.11.14.9409543","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/pdf\/10.1096\/fasebj.11.14.9409543","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T16:35:16Z","timestamp":1761669316000},"score":1,"resource":{"primary":{"URL":"https:\/\/faseb.onlinelibrary.wiley.com\/doi\/10.1096\/fasebj.11.14.9409543"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,12]]},"references-count":0,"journal-issue":{"issue":"14","published-print":{"date-parts":[[1997,12]]}},"alternative-id":["10.1096\/fasebj.11.14.9409543"],"URL":"https:\/\/doi.org\/10.1096\/fasebj.11.14.9409543","archive":["Portico"],"relation":{},"ISSN":["0892-6638","1530-6860"],"issn-type":[{"value":"0892-6638","type":"print"},{"value":"1530-6860","type":"electronic"}],"subject":[],"published":{"date-parts":[[1997,12]]},"assertion":[{"value":"1997-12-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}