{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T15:30:35Z","timestamp":1785771035148,"version":"3.56.0"},"reference-count":49,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Heart Disease"],"published-print":{"date-parts":[[2002,11]]},"DOI":"10.1097\/00132580-200211000-00007","type":"journal-article","created":{"date-parts":[[2003,11,17]],"date-time":"2003-11-17T05:10:49Z","timestamp":1069045849000},"page":"380-386","source":"Crossref","is-referenced-by-count":27,"title":["Are Antihypertensive Agents Protective Against Dementia? A Review of Clinical and Preclinical Data"],"prefix":"10.1097","volume":"4","author":[{"given":"William H.","family":"Frishman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20061208","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1126\/science.280.5362.395","volume":"280","author":"Wilmoth","year":"1998","journal-title":"Science"},{"key":"R3-7-20061208","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1161\/01.HYP.36.6.1079","volume":"36","author":"Harrington","year":"2000","journal-title":"Hypertension"},{"key":"R4-7-20061208","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0749-0690(05)70069-0","volume":"17","author":"Knopman","year":"2001","journal-title":"Clin Geriatr Med"},{"key":"R5-7-20061208","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S1098-3597(01)90047-X","volume":"3","author":"Chui","year":"2001","journal-title":"Clin Cornerstone"},{"key":"R6-7-20061208","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1001\/archinte.161.2.152","volume":"161","author":"Birkenh??ger","year":"2001","journal-title":"Arch Intern Med"},{"key":"R7-7-20061208","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/oxfordjournals.aje.a116868","volume":"138","author":"Elias","year":"1993","journal-title":"Am J Epidemiol"},{"key":"R8-7-20061208","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1001\/jama.1995.03530230032026","volume":"274","author":"Launer","year":"1995","journal-title":"JAMA"},{"key":"R9-7-20061208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/13825589608256627","volume":"3","author":"Swan","year":"1996","journal-title":"Aging Neuropsychol Cogn"},{"key":"R10-7-20061208","doi-asserted-by":"crossref","first-page":"1141","DOI":"10.1016\/S0140-6736(96)90608-X","volume":"347","author":"Skoog","year":"1996","journal-title":"Lancet"},{"key":"R11-7-20061208","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1161\/01.HYP.31.3.780","volume":"31","author":"Kilander","year":"1998","journal-title":"Hypertension"},{"key":"R12-7-20061208","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1038\/sj.jhh.1000551","volume":"11","author":"Starr","year":"1997","journal-title":"J Hum Hypertens"},{"key":"R13-7-20061208","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1001\/jama.281.5.438","volume":"281","author":"Glynn","year":"1999","journal-title":"JAMA"},{"key":"R14-7-20061208","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1212\/WNL.53.9.1948","volume":"53","author":"Tzourio","year":"1999","journal-title":"Neurology"},{"key":"R15-7-20061208","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1001\/archneur.56.8.991","volume":"56","author":"Guo","year":"1999","journal-title":"Arch Neurol"},{"key":"R16-7-20061208","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1136\/bmj.322.7300.1447","volume":"322","author":"Kivipelto","year":"2001","journal-title":"BMJ"},{"key":"R17-7-20061208","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1212\/WNL.56.1.42","volume":"56","author":"Knopman","year":"2001","journal-title":"Neurology"},{"key":"R18-7-20061208","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1212\/WNL.56.12.1683","volume":"56","author":"Kivipelto","year":"2001","journal-title":"Neurology"},{"key":"R19-7-20061208","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0146-2806(98)80010-8","volume":"23","author":"Frishman","year":"1998","journal-title":"Curr Probl Cardiol"},{"key":"R20-7-20061208","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1038\/sj.jhh.1001118","volume":"14","author":"Rigaud","year":"2000","journal-title":"J Hum Hypertens"},{"key":"R21-7-20061208","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1212\/WNL.56.7.921","volume":"56","author":"Dufouil","year":"2001","journal-title":"Neurology"},{"key":"R22-7-20061208","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1002\/1531-8249(199912)46:6<827::AID-ANA4>3.0.CO;2-H","volume":"46","author":"de Leeuw","year":"1999","journal-title":"Ann Neurol"},{"key":"R23-7-20061208","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1161\/01.STR.24.8.1148","volume":"24","author":"Nobili","year":"1993","journal-title":"Stroke"},{"key":"R24-7-20061208","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1111\/j.1749-6632.2000.tb06352.x","volume":"903","author":"Farkas","year":"2000","journal-title":"Ann NY Acad Sci"},{"key":"R25-7-20061208","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0140-6736(96)09328-2","volume":"349","author":"Hofman","year":"1997","journal-title":"Lancet"},{"key":"R26-7-20061208","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1212\/WNL.56.11.1539","volume":"56","author":"de Groot","year":"2001","journal-title":"Neurology"},{"key":"R27-7-20061208","first-page":"S21","volume":"18","author":"Tzourio","year":"2000","journal-title":"J Hypertens"},{"key":"R28-7-20061208","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1212\/WNL.51.4.986","volume":"51","author":"Swan","year":"1998","journal-title":"Neurology"},{"key":"R29-7-20061208","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1001\/archneur.58.4.643","volume":"58","author":"DeCarli","year":"2001","journal-title":"Arch Neurol"},{"key":"R30-7-20061208","doi-asserted-by":"crossref","first-page":"S115","DOI":"10.1097\/00002093-199912003-00017","volume":"13","author":"Kalaria","year":"1999","journal-title":"Alzheimer Dis Assoc Disord"},{"key":"R31-7-20061208","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/s11906-001-0062-2","volume":"3","author":"Sierra","year":"2001","journal-title":"Curr Hypertens Rep"},{"key":"R32-7-20061208","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/S0140-6736(98)03086-4","volume":"352","author":"Forette","year":"1998","journal-title":"Lancet"},{"key":"R33-7-20061208","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/S0140-6736(97)05381-6","volume":"350","author":"Staessen","year":"1997","journal-title":"Lancet"},{"key":"R33A-7-20061208","doi-asserted-by":"crossref","first-page":"2046","DOI":"10.1001\/archinte.162.18.2046","volume":"162","author":"Forette","year":"2002","journal-title":"Arch Intern Med"},{"key":"R34-7-20061208","doi-asserted-by":"crossref","first-page":"943","DOI":"10.1097\/00004872-199608000-00003","volume":"14","author":"Vanhanen","year":"1996","journal-title":"J Hypertens"},{"key":"R35-7-20061208","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/00041552-199905000-00012","volume":"8","author":"Starr","year":"1999","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"R36-7-20061208","doi-asserted-by":"crossref","first-page":"55A","DOI":"10.1016\/S0895-7061(01)01590-4","volume":"14","author":"Jacobson","year":"2001","journal-title":"Am J Hypertens"},{"key":"R37-7-20061208","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1161\/01.STR.31.10.2536","volume":"31","year":"2000","journal-title":"Stroke"},{"key":"R38-7-20061208","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1097\/00132580-200111000-00008","volume":"3","author":"Epstein","year":"2001","journal-title":"Heart Dis"},{"key":"R39-7-20061208","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1749-6632.1994.tb44429.x","volume":"747","author":"Schuurman","year":"1994","journal-title":"Ann NY Acad Sci"},{"key":"R40-7-20061208","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0197-4580(00)00225-6","volume":"22","author":"Farkas","year":"2001","journal-title":"Neurobiol Aging"},{"key":"R41-7-20061208","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1097\/00004872-199303001-00002","volume":"11","author":"van Zwieten","year":"1993","journal-title":"J Hypertens"},{"key":"R42-7-20061208","doi-asserted-by":"crossref","first-page":"2085","DOI":"10.1016\/S0047-6374(01)00318-9","volume":"122","author":"Sabbatini","year":"2001","journal-title":"Mech Ageing Dev"},{"key":"R43-7-20061208","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s004010000278","volume":"101","author":"Kemper","year":"2001","journal-title":"Acta Neuropathol"},{"key":"R44-7-20061208","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/S0047-6374(01)00233-0","volume":"122","author":"Sabbatini","year":"2001","journal-title":"Mech Ageing Dev"},{"key":"R45-7-20061208","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/01.HYP.37.4.1124","volume":"37","author":"Krenek","year":"2001","journal-title":"Hypertension"},{"key":"R46-7-20061208","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1080\/080370598438998","volume":"7","author":"Herbette","year":"1998","journal-title":"Blood Press"},{"key":"R47-7-20061208","doi-asserted-by":"crossref","first-page":"117A","DOI":"10.1016\/S0895-7061(02)02592-X","volume":"15","author":"Zanchetti","year":"2002","journal-title":"Am J Hypertens"},{"key":"R48-7-20061208","doi-asserted-by":"crossref","first-page":"58A","DOI":"10.1016\/S0895-7061(02)02424-X","volume":"15","author":"Hollenberg","year":"2002","journal-title":"Am J Hypertens"},{"key":"R49-7-20061208","doi-asserted-by":"crossref","first-page":"2090","DOI":"10.1001\/archinte.162.18.2090","volume":"162","author":"Murray","year":"2002","journal-title":"Arch Intern Med"}],"container-title":["Heart Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00132580-200211000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T14:39:24Z","timestamp":1785767964000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00132580-200211000-00007"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2002,11]]},"references-count":49,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.1097\/00132580-200211000-00007","relation":{},"ISSN":["1521-737X"],"issn-type":[{"value":"1521-737X","type":"print"}],"subject":[],"published":{"date-parts":[[2002,11]]}}}