{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T08:05:13Z","timestamp":1791014713689,"version":"4.1.0"},"reference-count":72,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1097\/01.all.0000191887.89773.cc","type":"journal-article","created":{"date-parts":[[2005,11,1]],"date-time":"2005-11-01T04:00:55Z","timestamp":1130817655000},"page":"496-503","source":"Crossref","is-referenced-by-count":34,"title":["TACItly changing tunes: farewell to a yin and yang of BAFF receptor and TACI in humoral immunity?"],"prefix":"10.1097","volume":"5","author":[{"given":"Ulrich","family":"Salzer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bodo","family":"Grimbacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210128","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1006\/clim.1999.4725","article-title":"Common variable immunodeficiency: clinical and immunological features of 248 patients","volume":"92","author":"Cunningham-Rundles","year":"1999","journal-title":"Clin Immunol"},{"key":"R2-4-20210128","doi-asserted-by":"crossref","first-page":"4408","DOI":"10.4049\/jimmunol.164.8.4408","article-title":"Fine mapping of IGAD1 in IgA deficiency and common variable immunodeficiency: identification and characterization of haplotypes shared by affected members of 101 multiple-case families","volume":"164","author":"Vo\u0159echovsk\u00fd","year":"2000","journal-title":"J Immunol"},{"key":"R3-4-20210128","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/S0065-2776(08)60744-0","article-title":"IgA deficiency","volume":"65","author":"Burrows","year":"1997","journal-title":"Adv Immunol"},{"key":"R4-4-20210128","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/ni902","article-title":"Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency","volume":"4","author":"Grimbacher","year":"2003","journal-title":"Nat Immunol"},{"key":"R5-4-20210128","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/00130832-200312000-00001","article-title":"The immunological synapse for B-cell memory: the role of the ICOS and its ligand for the longevity of humoral immunity","volume":"3","author":"Grimbacher","year":"2003","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"R6-4-20210128","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.clim.2004.07.002","article-title":"ICOS deficiency in patients with common variable immunodeficiency","volume":"113","author":"Salzer","year":"2004","journal-title":"Clin Immunol"},{"key":"R7-4-20210128","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1182\/blood-2003-12-4420","article-title":"Molecular analysis of a large cohort of patients with the hyper immunoglobulin M (IgM) syndrome","volume":"105","author":"Lee","year":"2005","journal-title":"Blood"},{"key":"R8-4-20210128","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1111\/j.1365-3083.2005.001603.x","article-title":"Normal ICOS, ICOSL and AID alleles in Danish patients with common variable immunodeficiency","volume":"61","author":"Ohm-Laursen","year":"2005","journal-title":"Scand J Immunol"},{"key":"R9-4-20210128","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1038\/ng1600","article-title":"Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans","volume":"37","author":"Salzer","year":"2005","journal-title":"Nat Genet"},{"key":"R10-4-20210128","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1038\/ng1601","article-title":"TACI is mutant in common variable immunodeficiency and IgA deficiency","volume":"37","author":"Castigli","year":"2005","journal-title":"Nat Genet"},{"key":"R14-4-20210128","doi-asserted-by":"crossref","first-page":"4464","DOI":"10.1182\/blood-2002-10-3123","article-title":"Macrophage- and dendritic cell-dependent regulation of human B-cell proliferation requires the TNF family ligand BAFF","volume":"101","author":"Craxton","year":"2003","journal-title":"Blood"},{"key":"R15-4-20210128","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1038\/ni829","article-title":"DCs induce CD40-independent Immunoglobulin class switching through BLyS and APRIL","volume":"3","author":"Litinskiy","year":"2002","journal-title":"Nat Immunol"},{"key":"R16-4-20210128","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1084\/jem.189.11.1747","article-title":"BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth","volume":"189","author":"Schneider","year":"1999","journal-title":"J Exp Med"},{"key":"R17-4-20210128","first-page":"1021","article-title":"APRIL\/TRDL-1, a tumor necrosis factor-like ligand, stimulates cell death","volume":"60","author":"Kelly","year":"2000","journal-title":"Cancer Res"},{"key":"R18-4-20210128","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1182\/blood-2004-02-0564","article-title":"Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases","volume":"105","author":"Scapini","year":"2005","journal-title":"Blood"},{"key":"R19-4-20210128","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1084\/jem.20030789","article-title":"Normal B cell homeostasis requires B cell activation factor production by radiation-resistant cells","volume":"198","author":"Gorelik","year":"2003","journal-title":"J Exp Med"},{"key":"R20-4-20210128","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1182\/blood-2003-06-2043","article-title":"Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival","volume":"103","author":"Novak","year":"2004","journal-title":"Blood"},{"key":"R21-4-20210128","doi-asserted-by":"crossref","first-page":"807","DOI":"10.4049\/jimmunol.173.2.807","article-title":"B cell-activating factor belonging to the TNF family (BAFF)-R is the principal BAFF receptor facilitating BAFF costimulation of circulating T and B cells","volume":"173","author":"Ng","year":"2004","journal-title":"J Immunol"},{"key":"R22-4-20210128","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1172\/JCI18025","article-title":"BAFF selectively enhances the survival of plasmablasts generated from human memory B cells","volume":"112","author":"Avery","year":"2003","journal-title":"J Clin Invest"},{"key":"R23-4-20210128","doi-asserted-by":"crossref","first-page":"812","DOI":"10.4049\/jimmunol.172.2.812","article-title":"TNF deficiency fails to protect BAFF transgenic mice against autoimmunity and reveals a predisposition to B cell lymphoma","volume":"172","author":"Batten","year":"2004","journal-title":"J Immunol"},{"key":"R24-4-20210128","doi-asserted-by":"crossref","first-page":"3903","DOI":"10.1073\/pnas.0307348101","article-title":"Impaired IgA class switching in APRIL-deficient mice","volume":"101","author":"Castigli","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R25-4-20210128","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.4049\/jimmunol.173.4.2331","article-title":"B cell-activating factor belonging to the TNF family acts through separate receptors to support B cell survival and T cell-independent antibody formation","volume":"173","author":"Shulga-Morskaya","year":"2004","journal-title":"J Immunol"},{"key":"R26-4-20210128","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1126\/science.1061964","article-title":"An essential role for BAFF in the normal development of B cells through a BCMA independent pathway","volume":"293","author":"Schiemann","year":"2001","journal-title":"Science"},{"key":"R27-4-20210128","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S1074-7613(01)00183-2","article-title":"TACI-Ig neutralizes molecules critical for B cell development and autoimmune disease. Impaired B cell maturation in mice lacking BLyS","volume":"15","author":"Gross","year":"2001","journal-title":"Immunity"},{"key":"R28-4-20210128","doi-asserted-by":"crossref","first-page":"2245","DOI":"10.4049\/jimmunol.173.4.2245","article-title":"TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology","volume":"173","author":"Sasaki","year":"2004","journal-title":"J Immunol"},{"key":"R29-4-20210128","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1084\/jem.20031330","article-title":"BCMA is essential for the survival of long-lived bone marrow plasma cells","volume":"199","author":"O'Connor","year":"2004","journal-title":"J Exp Med"},{"key":"R30-4-20210128","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S1074-7613(01)00130-3","article-title":"Regulation of the T-independent humoral response by TACI","volume":"14","author":"von B\u00fclow","year":"2001","journal-title":"Immunity"},{"key":"R31-4-20210128","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/89790","article-title":"Activation and accumulation of B cells in TACI-deficient mice","volume":"2","author":"Yan","year":"2001","journal-title":"Nat Immunol"},{"key":"R32-4-20210128","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S1074-7613(03)00025-6","article-title":"Loss of TACI causes fatal lymphoproliferation and autoimmunity, establishing TACI as an inhibitory BLyS receptor","volume":"18","author":"Seshasayee","year":"2003","journal-title":"Immunity"},{"key":"R33-4-20210128","doi-asserted-by":"crossref","first-page":"6883","DOI":"10.4049\/jimmunol.169.12.6883","article-title":"TNFR-associated factor-3 is associated with BAFF-R and negatively regulates BAFF-R-mediated NF-kappa B activation and IL-10 production","volume":"169","author":"Xu","year":"2002","journal-title":"J Immunol"},{"key":"R34-4-20210128","doi-asserted-by":"crossref","first-page":"958","DOI":"10.1038\/ni842","article-title":"BAFF-induced NEMO-independent processing of NF-kappa B2 in maturing B cells","volume":"3","author":"Claudio","year":"2002","journal-title":"Nat Immunol"},{"key":"R35-4-20210128","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/S1074-7613(02)00425-9","article-title":"BAFF\/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-kappaB2","volume":"17","author":"Kayagaki","year":"2002","journal-title":"Immunity"},{"key":"R36-4-20210128","doi-asserted-by":"crossref","first-page":"1322","DOI":"10.4049\/jimmunol.165.3.1322","article-title":"TNF receptor family member BCMA (B cell maturation) associates with TNF receptor-associated factor (TRAF) 1, TRAF2, and TRAF3 and activates NF-kappa B, elk-1, c-Jun N-terminal kinase, and p38 mitogen-activated protein kinase","volume":"165","author":"Hatzoglou","year":"2000","journal-title":"J Immunol"},{"key":"R37-4-20210128","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1084\/jem.192.1.137","article-title":"TACI is a TRAF-interacting receptor for TALL-1, a tumor necrosis factor family member involved in B cell regulation","volume":"192","author":"Xia","year":"2000","journal-title":"J Exp Med"},{"key":"R38-4-20210128","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1126\/science.278.5335.138","article-title":"NF-AT activation induced by a CAML-interacting member of the tumor necrosis factor receptor superfamily","volume":"278","author":"von B\u00fclow","year":"1997","journal-title":"Science"},{"key":"R39-4-20210128","doi-asserted-by":"crossref","first-page":"7218","DOI":"10.1074\/jbc.M411714200","article-title":"Structures of APRIL-receptor complexes: like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding","volume":"280","author":"Hymowitz","year":"2005","journal-title":"J Biol Chem"},{"key":"R40-4-20210128","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1126\/science.285.5425.260","article-title":"BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator","volume":"285","author":"Moore","year":"1999","journal-title":"Science"},{"key":"R41-4-20210128","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/S0092-8674(02)00631-1","article-title":"Crystal structure of sTALL-1 reveals a virus-like assembly of TNF family ligands","volume":"108","author":"Liu","year":"2002","journal-title":"Cell"},{"key":"R42-4-20210128","doi-asserted-by":"crossref","first-page":"38220","DOI":"10.1074\/jbc.M306852200","article-title":"DeltaBAFF, an alternate splice isoform that regulates receptor binding and biopresentation of the B cell survival cytokine, BAFF","volume":"278","author":"Gavin","year":"2003","journal-title":"J Biol Chem"},{"key":"R43-4-20210128","doi-asserted-by":"crossref","first-page":"319","DOI":"10.4049\/jimmunol.175.1.319","article-title":"deltaBAFF, a splice isoform of BAFF, opposes full-length BAFF activity in vivo in transgenic mouse models","volume":"175","author":"Gavin","year":"2005","journal-title":"J Immunol"},{"key":"R44-4-20210128","doi-asserted-by":"crossref","first-page":"4314","DOI":"10.4049\/jimmunol.169.8.4314","article-title":"BLyS and APRIL form biologically active heterotrimers that are expressed in patients with systemic immune-based rheumatic diseases","volume":"169","author":"Roschke","year":"2002","journal-title":"J Immunol"},{"key":"R45-4-20210128","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1084\/jem.192.7.953","article-title":"Attenuation of apoptosis underlies B lymphocyte stimulator enhancement of humoral immune response","volume":"192","author":"Do","year":"2000","journal-title":"J Exp Med"},{"key":"R46-4-20210128","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1084\/jem.192.10.1453","article-title":"BAFF mediates survival of peripheral immature B lymphocytes","volume":"192","author":"Batten","year":"2000","journal-title":"J Exp Med"},{"key":"R47-4-20210128","doi-asserted-by":"crossref","first-page":"3370","DOI":"10.1073\/pnas.97.7.3370","article-title":"Severe B cell hyperplasia and autoimmune disease in TALL-1 transgenic mice","volume":"97","author":"Khare","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R48-4-20210128","doi-asserted-by":"crossref","first-page":"1697","DOI":"10.1084\/jem.190.11.1697","article-title":"Mice transgenic for BAFF develop lymphocytic disorders along with autoimmune manifestations","volume":"190","author":"Mackay","year":"1999","journal-title":"J Exp Med"},{"key":"R49-4-20210128","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1128\/MCB.21.12.4067-4074.2001","article-title":"B-cell maturation protein, which binds the tumor necrosis factor family members BAFF and APRIL, is dispensable for humoral immune responses","volume":"21","author":"Xu","year":"2001","journal-title":"Mol Cell Biol"},{"key":"R50-4-20210128","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1126\/science.1061965","article-title":"BAFF-R, a newly identified TNF receptor that specifically interacts with BAFF","volume":"293","author":"Thompson","year":"2001","journal-title":"Science"},{"key":"R51-4-20210128","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1016\/S0960-9822(01)00481-X","article-title":"Identification of a novel receptor for B lymphocyte stimulator that is mutated in a mouse strain with severe B cell deficiency","volume":"11","author":"Yan","year":"2001","journal-title":"Curr Biol"},{"key":"R52-4-20210128","doi-asserted-by":"crossref","first-page":"761","DOI":"10.4049\/jimmunol.171.2.761","article-title":"NF-kappa B1 p50 is required for BLyS attenuation of apoptosis but dispensable for processing of NF-kappa B2 p100 to p52 in quiescent mature B cells","volume":"171","author":"Hatada","year":"2003","journal-title":"J Immunol"},{"key":"R53-4-20210128","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S1074-7613(04)00079-2","article-title":"Reduced competitiveness of autoantigen-engaged B cells due to increased dependence on BAFF","volume":"20","author":"Lesley","year":"2004","journal-title":"Immunity"},{"key":"R54-4-20210128","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1002\/eji.1830210506","article-title":"Phenotypic and genetic characterization of a unique B lymphocyte deficiency in strain A\/WySnJ mice","volume":"21","author":"Miller","year":"1991","journal-title":"Eur J Immunol"},{"key":"R55-4-20210128","doi-asserted-by":"crossref","first-page":"762","DOI":"10.4049\/jimmunol.172.2.762","article-title":"Cutting edge: BAFF regulates CD21\/35 and CD23 expression independent of its B cell survival function","volume":"172","author":"Gorelik","year":"2004","journal-title":"J Immunol"},{"key":"R56-4-20210128","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/eji.200324692","article-title":"The anti-apoptotic factor Bcl-2 can functionally substitute for the B cell survival but not for the marginal zone B cell differentiation activity of BAFF","volume":"34","author":"Tardivel","year":"2004","journal-title":"Eur J Immunol"},{"key":"R57-4-20210128","doi-asserted-by":"crossref","first-page":"6225","DOI":"10.4049\/jimmunol.167.11.6225","article-title":"T cell costimulation by the TNF ligand BAFF","volume":"167","author":"Huard","year":"2001","journal-title":"J Immunol"},{"key":"R58-4-20210128","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1093\/intimm\/dxh043","article-title":"BAFF production by antigen-presenting cells provides T cell co-stimulation","volume":"16","author":"Huard","year":"2004","journal-title":"Int Immunol"},{"key":"R59-4-20210128","doi-asserted-by":"crossref","first-page":"2750","DOI":"10.1002\/eji.200425198","article-title":"BAFF binding to T cell-expressed BAFF-R costimulates T cell proliferation and alloresponses","volume":"34","author":"Ye","year":"2004","journal-title":"Eur J Immunol"},{"key":"R60-4-20210128","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/embo-reports\/kve198","article-title":"Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase","volume":"2","author":"Lopez-Fraga","year":"2001","journal-title":"EMBO Rep"},{"key":"R61-4-20210128","doi-asserted-by":"crossref","first-page":"5711","DOI":"10.1093\/emboj\/cdf565","article-title":"An endogenous hybrid mRNA encodes TWE-PRIL, a functional cell surface TWEAK-APRIL fusion protein","volume":"21","author":"Pradet-Balade","year":"2002","journal-title":"EMBO J"},{"key":"R62-4-20210128","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1084\/jem.188.6.1185","article-title":"APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth","volume":"188","author":"Hahne","year":"1998","journal-title":"J Exp Med"},{"key":"R63-4-20210128","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1038\/sj.onc.1207350","article-title":"Abnormal production of the TNF-homologue APRIL increases the proliferation of human malignant glioblastoma cell lines via a specific receptor","volume":"23","author":"Deshayes","year":"2004","journal-title":"Oncogene"},{"key":"R64-4-20210128","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1084\/jem.20042309","article-title":"Identification of proteoglycans as the APRIL-specific binding partners","volume":"201","author":"Ingold","year":"2005","journal-title":"J Exp Med"},{"key":"R65-4-20210128","doi-asserted-by":"crossref","first-page":"3897","DOI":"10.1002\/j.1460-2075.1992.tb05482.x","article-title":"A new gene, BCM, on chromosome 16 is fused to the interleukin-2 gene by a t(4;16)(q26;p13) translocation in a malignant T cell lymphoma","volume":"11","author":"Laabi","year":"1992","journal-title":"EMBO J"},{"key":"R66-4-20210128","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1093\/intimm\/7.7.1093","article-title":"BCMAp: an integral membrane protein in the Golgi apparatus of human mature B lymphocytes","volume":"7","author":"Gras","year":"1995","journal-title":"Int Immunol"},{"key":"R67-4-20210128","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1093\/nar\/22.7.1147","article-title":"The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed","volume":"22","author":"Laabi","year":"1994","journal-title":"Nucl Acids Res"},{"key":"R68-4-20210128","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1007\/s003350010125","article-title":"Molecular cloning and functional characterization of murine transmembrane activator and CAML interactor (TACI) with chromosomal localization in human and mouse","volume":"11","author":"von Bulow","year":"2000","journal-title":"Mamm Genome"},{"key":"R69-4-20210128","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1182\/blood-2002-02-0558","article-title":"Aberrant expression of B-lymphocyte stimulator by B chronic lymphocytic leukemia cells: a mechanism for survival","volume":"100","author":"Novak","year":"2002","journal-title":"Blood"},{"key":"R70-4-20210128","doi-asserted-by":"crossref","first-page":"35478","DOI":"10.1074\/jbc.M005224200","article-title":"Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS","volume":"275","author":"Wu","year":"2000","journal-title":"J Biol Chem"},{"key":"R71-4-20210128","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1084\/jem.20032000","article-title":"TACI and BAFF-R mediate isotype switching in B cells","volume":"201","author":"Castigli","year":"2005","journal-title":"J Exp Med"},{"key":"R72-4-20210128","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1128\/MCB.23.4.1428-1440.2003","article-title":"Two adjacent trimeric Fas ligands are required for Fas signaling and formation of a death-inducing signaling complex","volume":"23","author":"Holler","year":"2003","journal-title":"Mol Cell Biol"},{"key":"R73-4-20210128","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1159\/000082107","article-title":"Human B lymphocyte malignancies: exploitation of BLyS and APRIL and their receptors","volume":"8","author":"Jelinek","year":"2005","journal-title":"Curr Dir Autoimmun"},{"key":"R74-4-20210128","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1159\/000082106","article-title":"The BAFF\/APRIL system: an important player in systemic rheumatic diseases","volume":"8","author":"Mackay","year":"2005","journal-title":"Curr Dir Autoimmun"},{"key":"R75-4-20210128","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1002\/art.11299","article-title":"Generation and characterization of LymphoStat-B, a human monoclonal antibody that antagonizes the bioactivities of B lymphocyte stimulator","volume":"48","author":"Baker","year":"2003","journal-title":"Arthritis Rheum"}],"container-title":["Current Opinion in Allergy & Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/01.all.0000191887.89773.cc","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:54:32Z","timestamp":1785855272000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00130832-200512000-00004"}},"subtitle":["New genetic defects in common variable immunodeficiency"],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":72,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1097\/01.all.0000191887.89773.cc","relation":{},"ISSN":["1528-4050"],"issn-type":[{"value":"1528-4050","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}