{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T11:30:00Z","timestamp":1791027000229,"version":"4.1.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Critical Care Medicine"],"published-print":{"date-parts":[[2007,3]]},"DOI":"10.1097\/01.ccm.0000256723.37586.a2","type":"journal-article","created":{"date-parts":[[2007,1,25]],"date-time":"2007-01-25T09:03:24Z","timestamp":1169715804000},"page":"886-892","source":"Crossref","is-referenced-by-count":57,"title":["Toll-like receptor 2 activation by bacterial peptidoglycan\u2013associated lipoprotein activates cardiomyocyte inflammation and contractile dysfunction"],"prefix":"10.1097","volume":"35","author":[{"given":"Xinsheng","family":"Zhu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aranya","family":"Bagchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huailong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten J.","family":"Kirschning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roger J.","family":"Hajjar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Chao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith","family":"Hellman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-29-20160304","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1053\/jcan.2001.22317","volume":"15","author":"Kumar","year":"2001","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"R2-29-20160304","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1053\/jcan.2001.25003","volume":"15","author":"Kumar","year":"2001","journal-title":"J Cardiothorac Vasc Anesth"},{"key":"R3-29-20160304","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1128\/IAI.68.5.2566-2572.2000","volume":"68","author":"Hellman","year":"2000","journal-title":"Infect Immun"},{"key":"R4-29-20160304","doi-asserted-by":"crossref","first-page":"14274","DOI":"10.1074\/jbc.M109696200","volume":"277","author":"Hellman","year":"2002","journal-title":"J Biol Chem"},{"key":"R5-29-20160304","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1086\/427815","volume":"191","author":"Liang","year":"2005","journal-title":"J Infect Dis"},{"key":"R6-29-20160304","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1126\/science.1631560","volume":"257","author":"Finkel","year":"1992","journal-title":"Science"},{"key":"R7-29-20160304","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1093\/cvr\/27.8.1486","volume":"27","author":"Evans","year":"1993","journal-title":"Cardiovasc Res"},{"key":"R8-29-20160304","doi-asserted-by":"crossref","first-page":"R577","DOI":"10.1152\/ajpcell.1998.274.3.C577","volume":"274","author":"Meldrum","year":"1998","journal-title":"Am J Physiol"},{"key":"R9-29-20160304","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1161\/01.RES.78.1.154","volume":"78","author":"Murray","year":"1996","journal-title":"Circ Res"},{"key":"R10-29-20160304","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1152\/jappl.1994.76.3.1060","volume":"76","author":"Walley","year":"1994","journal-title":"J Appl Physiol"},{"key":"R11-29-20160304","first-page":"H668","volume":"263","author":"Eichenholz","year":"1992","journal-title":"Am J Physiol"},{"key":"R12-29-20160304","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1086\/376453","volume":"188","author":"Hellman","year":"2003","journal-title":"J Infect Dis"},{"key":"R13-29-20160304","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4049\/jimmunol.168.1.348","volume":"168","author":"Wooten","year":"2002","journal-title":"J Immunol"},{"key":"R14-29-20160304","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/nm1008","volume":"10","author":"Bjorkbacka","year":"2004","journal-title":"Nat Med"},{"key":"R15-29-20160304","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/0076-6879(94)35143-0","volume":"235","author":"Nikaido","year":"1994","journal-title":"Methods Enzymol"},{"key":"R16-29-20160304","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/oxfordjournals.jbchem.a133199","volume":"89","author":"Mizuno","year":"1981","journal-title":"J Biochem (Tokyo)"},{"key":"R17-29-20160304","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1128\/JCM.21.2.211-216.1985","volume":"21","author":"Novitsky","year":"1985","journal-title":"J Clin Microbiol"},{"key":"R18-29-20160304","first-page":"H986","volume":"277","author":"Scherrer-Crosbie","year":"1999","journal-title":"Am J Physiol"},{"key":"R19-29-20160304","doi-asserted-by":"crossref","first-page":"2075","DOI":"10.1006\/jmcc.2000.1239","volume":"32","author":"Lim","year":"2000","journal-title":"J Mol Cell Cardiol"},{"key":"R20-29-20160304","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/S0022-3565(24)35291-7","volume":"292","author":"Kimura","year":"2000","journal-title":"J Pharmacol Exp Ther"},{"key":"R21-29-20160304","doi-asserted-by":"crossref","first-page":"21997","DOI":"10.1074\/jbc.M413676200","volume":"280","author":"Chao","year":"2005","journal-title":"J Biol Chem"},{"key":"R22-29-20160304","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1111\/j.1699-0463.1990.tb01017.x","volume":"98","author":"Henriksen","year":"1990","journal-title":"APMIS"},{"key":"R23-29-20160304","doi-asserted-by":"crossref","first-page":"2181","DOI":"10.1128\/JCM.25.11.2181-2188.1987","volume":"25","author":"Henriksen","year":"1987","journal-title":"J Clin Microbiol"},{"key":"R24-29-20160304","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1097\/01.CCM.0000152223.27176.A6","volume":"33","author":"Zhu","year":"2005","journal-title":"Crit Care Med"},{"key":"R25-29-20160304","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1097\/00024382-200209000-00014","volume":"18","author":"Ren","year":"2002","journal-title":"Shock"},{"key":"R26-29-20160304","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/S0968-0004(02)02145-X","volume":"27","author":"Janssens","year":"2002","journal-title":"Trends Biochem Sci"},{"key":"R27-29-20160304","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1172\/JCI20762","volume":"113","author":"Meng","year":"2004","journal-title":"J Clin Invest"},{"key":"R28-29-20160304","doi-asserted-by":"crossref","first-page":"3693","DOI":"10.1161\/01.CIR.0000143081.13042.04","volume":"110","author":"Knuefermann","year":"2004","journal-title":"Circulation"},{"key":"R29-29-20160304","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1161\/01.RES.0000144175.70140.8c","volume":"95","author":"Tavener","year":"2004","journal-title":"Circ Res"},{"key":"R30-29-20160304","doi-asserted-by":"crossref","first-page":"H577","DOI":"10.1152\/ajpheart.00745.2004","volume":"288","author":"Binck","year":"2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"R31-29-20160304","first-page":"581","volume":"424","author":"Gershon","year":"2003","journal-title":"Nature"},{"key":"R32-29-20160304","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1164\/ajrccm.152.2.7633696","volume":"152","author":"Herbertson","year":"1995","journal-title":"Am J Respir Crit Care Med"},{"key":"R33-29-20160304","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1378\/chest.101.3.810","volume":"101","author":"Vincent","year":"1992","journal-title":"Chest"},{"key":"R34-29-20160304","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1097\/00003246-199609000-00002","volume":"24","author":"Cohen","year":"1996","journal-title":"Crit Care Med"},{"key":"R35-29-20160304","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1016\/S0140-6736(05)60602-2","volume":"351","author":"Abraham","year":"1998","journal-title":"Lancet"}],"container-title":["Critical Care Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/01.CCM.0000256723.37586.A2","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T05:49:53Z","timestamp":1736747393000},"score":1,"resource":{"primary":{"URL":"http:\/\/journals.lww.com\/00003246-200703000-00029"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2007,3]]},"references-count":35,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.1097\/01.ccm.0000256723.37586.a2","relation":{},"ISSN":["0090-3493"],"issn-type":[{"value":"0090-3493","type":"print"}],"subject":[],"published":{"date-parts":[[2007,3]]}}}