{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T14:45:17Z","timestamp":1785854717662,"version":"3.56.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2005,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title\/>\n                    <jats:p>The \u201cman-in-the-barrel\u201d syndrome is a descriptive term that was used in the past for patients with complete flaccid paralysis of the upper extremities caused by symmetric \u201cwatershed\u201d brain infarction after cardiovascular arrest or cardiac surgery. However, it is now evident that this syndrome can occur in acute and chronic diseases of the upper and lower motor neuron. We describe a 48-year-old woman with rapid and severe progressive weakness and wasting of both upper extremities mimicking the \u201cman-in-the-barrel\u201d syndrome. The neurologic and electrophysiological findings were compatible with anterior horn cell disease affecting the cervical spinal cord segments. There were only minimal signs suggesting the presence of myelopathy. After the initial rapid onset, progression during the 7 years of follow up was minimal. An extensive etiologic workup disclosed infection with HTLV-1.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/01.cnd.0000150262.44324.99","type":"journal-article","created":{"date-parts":[[2005,2,24]],"date-time":"2005-02-24T04:28:36Z","timestamp":1109219316000},"page":"127-131","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":9,"title":["HTLV-1 Associated Motor Neuron Disease Mimicking \u201cMan-in-the-Barrel\u201d Syndrome"],"prefix":"10.1097","volume":"6","author":[{"given":"Gabriel","family":"Vainstein","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos R","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natan","family":"Gadoth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-5-20240808","first-page":"279","article-title":"Distal field infarction.","volume":"12","author":"Mohr","year":"1969","journal-title":"Neurology"},{"key":"R2-5-20240808","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1161\/01.STR.22.8.1078","article-title":"Review of the variability of the territories of the major cerebral arteries.","volume":"22","author":"Van der Zwan","year":"1991","journal-title":"Stroke"},{"key":"R3-5-20240808","first-page":"845","article-title":"A new agglutination test for serum antibodies to adult T-cell leukemia virus.","volume":"75","author":"Ikeda","year":"1984","journal-title":"Gann"},{"key":"R4-5-20240808","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0140-6736(85)92734-5","article-title":"Antibodies to human T-lymphotrophic virus type-I in patients with tropical spastic paraparesis.","volume":"2","author":"Gessain","year":"1985","journal-title":"Lancet"},{"key":"R5-5-20240808","first-page":"190","article-title":"Involvement of peripheral nervous system and skeletal muscles in HTLV1-related paraplegia. Study of 70 cases seen in Martinique.","volume":"151","author":"Samdja","year":"1995","journal-title":"Rev Neurol (Paris)"},{"key":"R6-5-20240808","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1002\/ana.410340508","article-title":"Spastic paraparesis associated with human T-lymphotropic virus type I: a clinical, serological, and genomic study in Iranian-born Mashhadi Jews.","volume":"34","author":"Achiron","year":"1993","journal-title":"Ann Neurol"},{"key":"R7-5-20240808","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1002\/(SICI)1096-9071(199811)56:3<269::AID-JMV16>3.0.CO;2-9","article-title":"Ethnic cluster of HTLV-I infection in Israel among the Mashhadi Jewish population.","volume":"56","author":"Miller","year":"1998","journal-title":"J Med Virol"},{"key":"R8-5-20240808","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1089\/aid.1996.12.1185","article-title":"Prevalence of HTLV type I infection in Iran: a serological and genetic study.","volume":"12","author":"Safai","year":"1996","journal-title":"AIDS Res Hum Retroviruses"},{"key":"R11-5-20240808","first-page":"2061","article-title":"Peripheral man-in-the-barrel syndrome.","volume":"25","author":"Uterga","year":"1997","journal-title":"Rev Neurol"},{"key":"R12-5-20240808","first-page":"138","article-title":"Man-in-the-barrel syndrome.","volume":"14","author":"Camino Oritz de Barron","year":"1999","journal-title":"Neurologia"},{"key":"R13-5-20240808","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1600-0404.1998.tb05977.x","article-title":"Man-in-the-barrel syndrome caused by cervical spinal cord infarction.","volume":"97","author":"Berg","year":"1998","journal-title":"Acta Neurol Scand"},{"key":"R14-5-20240808","first-page":"40","article-title":"Pure motor neuropathy after radiation therapy: 6 cases.","volume":"154","author":"Lalu","year":"1998","journal-title":"Rev Neurol"},{"key":"R15-5-20240808","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1227\/00006123-197910000-00003","article-title":"Cervical spondylotic radiculopathy producing motor manifestations mimicking primary muscular atrophy.","volume":"5","author":"Dorsen","year":"1979","journal-title":"Neurosurgery"},{"key":"R16-5-20240808","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1097\/00007632-199802150-00008","article-title":"Cervical spondylotic amyotrophy.","volume":"23","author":"Kameyama","year":"1998","journal-title":"Spine"},{"key":"R17-5-20240808","first-page":"427","article-title":"The clinical syndrome of amyotrophic lateral sclerosis.","volume":"32","author":"Mulder","year":"1957","journal-title":"Mayo Clin Proc"},{"key":"R18-5-20240808","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1002\/ana.410030512","article-title":"Juvenile type of distal and segmental muscular atrophy of upper extremities.","volume":"3","author":"Sobue","year":"1978","journal-title":"Ann Neurol"},{"key":"R19-5-20240808","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1212\/WNL.40.1.118","article-title":"A syndrome of asymmetric limb weakness with motor conduction block.","volume":"40","author":"Krarup","year":"1990","journal-title":"Neurology"},{"key":"R20-5-20240808","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1212\/WNL.53.5.1071","article-title":"Brachial amyotrophic diplegia: a slowly progressive motor neuron disorder.","volume":"53","author":"Katz","year":"1999","journal-title":"Neurology"},{"key":"R21-5-20240808","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1136\/jnnp.65.6.950","article-title":"Flail arm syndrome: a distinctive variant of amyotrophic lateral sclerosis.","volume":"65","author":"Hu","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry"}],"container-title":["Journal of Clinical Neuromuscular Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00131402-200503000-00005","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T13:45:36Z","timestamp":1785851136000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00131402-200503000-00005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,3]]},"references-count":19,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1097\/01.cnd.0000150262.44324.99","relation":{},"ISSN":["1522-0443"],"issn-type":[{"value":"1522-0443","type":"print"}],"subject":[],"published":{"date-parts":[[2005,3]]}}}