{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T04:53:53Z","timestamp":1769230433413,"version":"3.49.0"},"reference-count":52,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2006,4]]},"DOI":"10.1097\/01.fpc.0000199501.54466.de","type":"journal-article","created":{"date-parts":[[2008,5,4]],"date-time":"2008-05-04T11:08:48Z","timestamp":1209899328000},"page":"253-263","source":"Crossref","is-referenced-by-count":41,"title":["Polymorphisms of the FAS and FAS ligand genes associated with risk of cutaneous malignant melanoma"],"prefix":"10.1097","volume":"16","author":[{"given":"Chunying","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Larson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengdong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhensheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sara S.","family":"Strom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey E.","family":"Gershenwald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor G.","family":"Prieto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey E.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Merrick I.","family":"Ross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul F.","family":"Mansfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janice N.","family":"Cormier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madeleine","family":"Duvic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth A.","family":"Grimm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingyi","family":"Wei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-4-20210212","article-title":"Cancer Facts and Figures, 2005","year":"2005"},{"key":"R2-4-20210212","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1056\/NEJM199904293401707","article-title":"The pathogenesis of melanoma induced by ultraviolet radiation","volume":"340","author":"Gilchrest","year":"1999","journal-title":"N Engl J Med"},{"key":"R3-4-20210212","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1093\/jnci\/95.4.308","article-title":"Repair of UV light-induced DNA damage and risk of cutaneous malignant melanoma","volume":"95","author":"Wei","year":"2003","journal-title":"J Natl Cancer Inst"},{"key":"R4-4-20210212","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.canlet.2004.09.035","article-title":"UV induced bystander signaling leading to apoptosis","volume":"223","author":"Banerjee","year":"2005","journal-title":"Cancer Lett"},{"key":"R5-4-20210212","doi-asserted-by":"crossref","first-page":"5795","DOI":"10.1074\/jbc.M406334200","article-title":"Alpha-melanocyte-stimulating hormone protects from ultraviolet radiation-induced apoptosis and DNA damage","volume":"280","author":"Bohm","year":"2005","journal-title":"J Biol Chem"},{"key":"R6-4-20210212","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0163-7258(00)00096-6","article-title":"Death the Fas way: regulation and pathophysiology of CD95 and its ligand","volume":"88","author":"Sharma","year":"2000","journal-title":"Pharmacol Ther"},{"key":"R7-4-20210212","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1038\/sj.cdd.4401179","article-title":"Signaling and transcriptional control of Fas ligand gene expression","volume":"10","author":"Kavurma","year":"2003","journal-title":"Cell Death Differ"},{"key":"R8-4-20210212","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1023\/A:1024112231953","article-title":"Mad dogs, Englishmen and apoptosis: the role of cell death in UV-induced skin cancer","volume":"8","author":"Guzman","year":"2003","journal-title":"Apoptosis"},{"key":"R9-4-20210212","doi-asserted-by":"crossref","first-page":"3152","DOI":"10.1038\/sj.onc.1206456","article-title":"Death receptors and melanoma resistance to apoptosis","volume":"22","author":"Ivanov","year":"2003","journal-title":"Oncogene"},{"key":"R10-4-20210212","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1046\/j.1523-1747.2000.00164.x","article-title":"Inhibition of growth of melanoma cells by CD95 (Fas\/APO-1) gene transfer in vivo","volume":"115","author":"Aragane","year":"2000","journal-title":"J Invest Dermatol"},{"key":"R11-4-20210212","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.imlet.2005.06.008","article-title":"Role of apoptosis in basal cell and squamous cell carcinoma formation","volume":"100","author":"Erb","year":"2005","journal-title":"Immunol Lett"},{"key":"R12-4-20210212","doi-asserted-by":"crossref","first-page":"1785","DOI":"10.1016\/S0002-9440(10)65434-X","article-title":"Alterations of Fas (Apo-1\/CD95) gene in cutaneous malignant melanoma","volume":"154","author":"Shin","year":"1999","journal-title":"Am J Pathol"},{"key":"R13-4-20210212","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1093\/rheumatology\/38.7.645","article-title":"Evaluation of a new Apo-1\/Fas promoter polymorphism in rheumatoid arthritis and systemic lupus erythematosus patients","volume":"38","author":"Huang","year":"1999","journal-title":"Rheumatology (Oxford)"},{"key":"R14-4-20210212","first-page":"4327","article-title":"Functional FAS promoter polymorphisms are associated with increased risk of acute myeloid leukemia","volume":"63","author":"Sibley","year":"2003","journal-title":"Cancer Res"},{"key":"R15-4-20210212","doi-asserted-by":"crossref","first-page":"132","DOI":"10.4049\/jimmunol.170.1.132","article-title":"A novel polymorphic CAAT\/enhancer-binding protein beta element in the FasL gene promoter alters Fas ligand expression: a candidate background gene in African American systemic lupus erythematosus patients","volume":"170","author":"Wu","year":"2003","journal-title":"J Immunol"},{"key":"R16-4-20210212","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0198-8859(02)00775-9","article-title":"Fas ligand gene polymorphisms are not associated with Hashimoto's thyroiditis and Graves\u2019 disease","volume":"64","author":"Stuck","year":"2003","journal-title":"Hum Immunol"},{"key":"R17-4-20210212","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/sj.cdd.4400964","article-title":"Genetic polymorphisms of Fas (CD95) and FasL (CD178) in human longevity: studies on centenarians","volume":"9","author":"Pinti","year":"2002","journal-title":"Cell Death Differ"},{"key":"R18-4-20210212","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1136\/jmg.2004.030106","article-title":"Functional polymorphisms in cell death pathway genes FAS and FASL contribute to risk of lung cancer","volume":"42","author":"Zhang","year":"2005","journal-title":"J Med Genet"},{"key":"R19-4-20210212","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/sj.leu.2401708","article-title":"Lack of CD95\/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas","volume":"14","author":"Bertoni","year":"2000","journal-title":"Leukemia"},{"key":"R20-4-20210212","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1093\/jnci\/djh289","article-title":"Re: polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma","volume":"96","author":"Krippl","year":"2004","journal-title":"J Natl Cancer Inst"},{"key":"R21-4-20210212","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1093\/jnci\/djh187","article-title":"Polymorphisms of death pathway genes FAS and FASL in esophageal squamous-cell carcinoma","volume":"96","author":"Sun","year":"2004","journal-title":"J Natl Cancer Inst"},{"key":"R22-4-20210212","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.ygyno.2005.04.001","article-title":"Fas gene promoter -670 polymorphism (A\/G) is associated with cervical carcinogenesis","volume":"98","author":"Ueda","year":"2005","journal-title":"Gynecol Oncol"},{"key":"R23-4-20210212","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1084\/jem.20050707","article-title":"FASL -844C polymorphism is associated with increased activation-induced T cell death and risk of cervical cancer","volume":"202","author":"Sun","year":"2005","journal-title":"J Exp Med"},{"key":"R24-4-20210212","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1002\/ijc.10800","article-title":"Single nucleotide polymorphism at Fas promoter is associated with cervical carcinogenesis","volume":"103","author":"Lai","year":"2003","journal-title":"Int J Cancer"},{"key":"R25-4-20210212","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0301-472X(00)00623-8","article-title":"Mutation analysis of the FAS and TNFR apoptotic cascade genes in hematological malignancies","volume":"29","author":"Rozenfeld-Granot","year":"2001","journal-title":"Exp Hematol"},{"key":"R26-4-20210212","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.imlet.2005.03.016","article-title":"Attenuation of the Fas-L independent b16bL6 melanoma lymphocidic capacity by H-2\u2009K class I molecules","volume":"100","author":"Kellman-Pressman","year":"2005","journal-title":"Immunol Lett"},{"key":"R27-4-20210212","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1023\/B:CLIN.0000037727.28386.4e","article-title":"Essential role for hematopoietic Fas ligand (FasL) in the suppression of melanoma lung metastasis revealed in bone marrow chimeric mice","volume":"21","author":"Hall","year":"2004","journal-title":"Clin Exp Metastasis"},{"key":"R28-4-20210212","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.yexcr.2004.05.011","article-title":"HLA-DR signaling inhibits Fas-mediated apoptosis in A375 melanoma cells","volume":"299","author":"Aoudjit","year":"2004","journal-title":"Exp Cell Res"},{"key":"R29-4-20210212","doi-asserted-by":"crossref","first-page":"9131","DOI":"10.1038\/sj.onc.1207228","article-title":"CD95\/Fas signaling in human melanoma cells: conditional expression of CD95\u2009l\/FasL overcomes the intrinsic apoptosis resistance of malignant melanoma and inhibits growth and progression of human melanoma xenotransplants","volume":"22","author":"Eberle","year":"2003","journal-title":"Oncogene"},{"key":"R30-4-20210212","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1097\/00008390-200304000-00007","article-title":"Interferon-gamma and anti-Fas antibody-induced apoptosis in human melanoma cell lines and its relationship to bcl-2 cleavage and bak expression","volume":"13","author":"Kamei","year":"2003","journal-title":"Melanoma Res"},{"key":"R31-4-20210212","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1200\/JCO.2001.19.16.3635","article-title":"Final version of the American Joint Committee on Cancer staging system for cutaneous melanoma","volume":"19","author":"Balch","year":"2001","journal-title":"J Clin Oncol"},{"key":"R32-4-20210212","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1001\/archderm.1988.01670060015008","article-title":"The validity and practicality of sun-reactive skin types I through VI","volume":"124","author":"Fitzpatrick","year":"1988","journal-title":"Arch Dermatol"},{"key":"R33-4-20210212","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1093\/bioinformatics\/bth071","article-title":"2LD, GENECOUNTING and HAP: computer programs for linkage disequilibrium analysis","volume":"20","author":"Zhao","year":"2004","journal-title":"Bioinformatics"},{"key":"R34-4-20210212","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1046\/j.1469-1809.2001.6540395.x","article-title":"Sampling variance and distribution of the D\u2032 measure of overall gametic disequilibrium between multiallelic loci","volume":"65","author":"Zapata","year":"2001","journal-title":"Ann Hum Genet"},{"key":"R35-4-20210212","doi-asserted-by":"crossref","first-page":"1162","DOI":"10.1086\/379378","article-title":"A comparison of bayesian methods for haplotype reconstruction from population genotype data","volume":"73","author":"Stephens","year":"2003","journal-title":"Am J Hum Genet"},{"key":"R36-4-20210212","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1086\/319501","article-title":"A new statistical method for haplotype reconstruction from population data","volume":"68","author":"Stephens","year":"2001","journal-title":"Am J Hum Genet"},{"key":"R37-4-20210212","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1093\/carcin\/21.3.485","article-title":"Apoptosis in cancer","volume":"21","author":"Lowe","year":"2000","journal-title":"Carcinogenesis"},{"key":"R38-4-20210212","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/35077213","article-title":"Proliferation cell cycle and apoptosis in cancer","volume":"17","author":"Evan","year":"2001","journal-title":"Nature"},{"key":"R39-4-20210212","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1189\/jlb.71.6.907","article-title":"Immune escape of tumors: apoptosis resistance and tumor counterattack","volume":"71","author":"Igney","year":"2002","journal-title":"J Leukoc Biol"},{"key":"R40-4-20210212","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.yexcr.2004.11.023","article-title":"The novel tumor suppressor p33ING2 enhances UVB-induced apoptosis in human melanoma cells","volume":"304","author":"Chin","year":"2005","journal-title":"Exp Cell Res"},{"key":"R41-4-20210212","doi-asserted-by":"crossref","first-page":"6775","DOI":"10.1158\/0008-5472.CAN-04-0508","article-title":"Autocrine secretion of Fas ligand shields tumor cells from Fas-mediated killing by cytotoxic lymphocytes","volume":"64","author":"Hallermalm","year":"2004","journal-title":"Cancer Res"},{"key":"R42-4-20210212","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1126\/science.7533326","article-title":"The Fas death factor","volume":"267","author":"Nagata","year":"1995","journal-title":"Science"},{"key":"R43-4-20210212","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1016\/0092-8674(93)90326-L","article-title":"Molecular cloning and expression of the Fas ligand, a novel member of the tumor necrosis factor family","volume":"75","author":"Suda","year":"1993","journal-title":"Cell"},{"key":"R44-4-20210212","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1084\/jem.184.3.1075","article-title":"The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand","volume":"184","author":"O\u2019Connell","year":"1996","journal-title":"J Exp Med"},{"key":"R45-4-20210212","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0169-5002(03)00276-9","article-title":"Fas A670G polymorphism, apoptotic capacity in lymphocyte cultures, and risk of lung cancer","volume":"42","author":"Wang","year":"2003","journal-title":"Lung Cancer"},{"key":"R46-4-20210212","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/j.ajog.2004.06.106","article-title":"A single nucleotide A>G polymorphism at position -670 in the Fas gene promoter: relationship to preterm premature rupture of fetal membranes in multifetal pregnancies","volume":"192","author":"Kalish","year":"2005","journal-title":"Am J Obstet Gynecol"},{"key":"R47-4-20210212","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1038\/sj.gene.6364158","article-title":"The -844C\/T polymorphism in the Fas ligand promoter associates with Taiwanese SLE","volume":"6","author":"Chen","year":"2005","journal-title":"Genes Immun"},{"key":"R48-4-20210212","first-page":"163","article-title":"Human melanoma cell line UV responses show independency of p53 function","volume":"10","author":"Haapajarvi","year":"1999","journal-title":"Cell Growth Differ"},{"key":"R49-4-20210212","doi-asserted-by":"crossref","first-page":"3003","DOI":"10.1038\/sj.onc.1203602","article-title":"p38 protects human melanoma cells from UV-induced apoptosis through down-regulation of NF-kappaB activity and Fas expression","volume":"19","author":"Ivanov","year":"2000","journal-title":"Oncogene"},{"key":"R50-4-20210212","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.4049\/jimmunol.161.3.1220","article-title":"Human melanoma-reactive CD4+ and CD8+ CTL clones resist Fas ligand-induced apoptosis and use Fas\/Fas ligand-independent mechanisms for tumor killing","volume":"161","author":"Rivoltini","year":"1998","journal-title":"J Immunol"},{"key":"R51-4-20210212","first-page":"811","article-title":"Participation of pigment epithelium of iris and ciliary body in ocular immune privilege. 1. Inhibition of T-cell activation in vitro by direct cell-to-cell contact","volume":"41","author":"Yoshida","year":"2000","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R52-4-20210212","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.1002\/eji.1830201115","article-title":"Dual effect of ciliary body cells on T lymphocyte proliferation","volume":"20","author":"Helbig","year":"1990","journal-title":"Eur J Immunol"}],"container-title":["Pharmacogenetics and Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/01.fpc.0000199501.54466.de","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,18]],"date-time":"2023-05-18T03:25:39Z","timestamp":1684380339000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01213011-200604000-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,4]]},"references-count":52,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.1097\/01.fpc.0000199501.54466.de","relation":{},"ISSN":["1744-6872"],"issn-type":[{"value":"1744-6872","type":"print"}],"subject":[],"published":{"date-parts":[[2006,4]]}}}