{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:22:21Z","timestamp":1745554941172,"version":"3.40.4"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,5]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n          <jats:p>Marjolin ulcers are aggressive, cutaneous malignancies typically arising from chronic, nonhealing wounds. The presence of an obvious defect often masks this potentially life-threatening condition, making detection difficult and frequently leading to delayed diagnosis. Most cases of Marjolin ulcers are squamous cell carcinoma (SCC) in histology. Unlike for other common cutaneous malignancies, no clear guidelines or protocols are in place for early surveillance and management of Marjolin ulcers. Given the aggressive nature of this malignancy when associated with metastasis, early diagnosis and intervention are imperative. We present a unique case describing an immunocompromised patient with an extensive surgical abdominal history who had developed a cutaneous mass determined to be well-differentiated invasive SCC on final histology. The mass was superimposed over a chronic enteroatmospheric fistula that was present for more than 20 years.<\/jats:p>","DOI":"10.1097\/01.jaa.0000000000000074","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T18:02:42Z","timestamp":1745517762000},"page":"32-34","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Squamous cell carcinoma arising from chronic enteroatmospheric fistula"],"prefix":"10.1097","volume":"38","author":[{"given":"Phillip","family":"Alix","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Genesis","family":"Moseley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shai","family":"Chazin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Courtland","family":"Polley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Bowers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda P.","family":"Stanton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2025,4,24]]},"reference":[{"key":"R1-20250424","first-page":"1435","article-title":"Enterocutaneous fistula: evidence-based management","volume":"2","author":"Dumas","year":"2017","journal-title":"Clin Surg"},{"key":"R2-20250424","doi-asserted-by":"crossref","first-page":"564379","DOI":"10.3389\/fnut.2020.564379","article-title":"Nutritional management of patients with enterocutaneous fistulas: practice and progression","volume":"7","author":"Tang","year":"2020","journal-title":"Front Nutr"},{"issue":"245","key":"R3-20250424","first-page":"93","article-title":"Management of enterocutaneous fistula: a review","volume":"60","author":"Ghimire","year":"2022","journal-title":"JNMA J Nepal Med Assoc"},{"issue":"4","key":"R4-20250424","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1177\/0884533612444541","article-title":"Enteroatmospheric fistula: from soup to nuts","volume":"27","author":"Majercik","year":"2012","journal-title":"Nutr Clin Pract"},{"issue":"3","key":"R5-20250424","first-page":"60","article-title":"A comprehensive review on Marjolin's ulcers: diagnosis and treatment","volume":"3","author":"Pekarek","year":"2011","journal-title":"J Am Col Certif Wound Spec"},{"issue":"7","key":"R6-20250424","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.kjms.2017.04.008","article-title":"Clinicopathological evaluation of Marjolin ulcers over two decades","volume":"33","author":"Oru\u00e7","year":"2017","journal-title":"Kaohsiung J Med Sci"},{"issue":"7","key":"R7-20250424","first-page":"e16476","article-title":"Marjolin's ulcer: mesh-related vaginal cutaneous fistula with superimposed osteomyelitis and neoplastic transformation","volume":"13","author":"Gajarawala","year":"2021","journal-title":"Cureus"},{"issue":"3","key":"R8-20250424","first-page":"197","article-title":"Marjolin's ulcer in chronic wounds\u2014review of available literature","volume":"21","author":"Bazali\u0144ski","year":"2017","journal-title":"Contemp Oncol (Pozn)"},{"issue":"10","key":"R9-20250424","doi-asserted-by":"crossref","first-page":"507","DOI":"10.12998\/wjcc.v2.i10.507","article-title":"Marjolin's ulcers in the post-burned lesions and scars","volume":"2","author":"Saaiq","year":"2014","journal-title":"World J Clin Cases"},{"issue":"12","key":"R10-20250424","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1097\/01.ASW.0000720252.15291.18","article-title":"Marjolin ulcer: a comprehensive review","volume":"33","author":"Khan","year":"2020","journal-title":"Adv Skin Wound Care"}],"container-title":["JAAPA"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/01.JAA.0000000000000074","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T18:02:44Z","timestamp":1745517764000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/01.JAA.0000000000000074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1097\/01.jaa.0000000000000074","relation":{},"ISSN":["1547-1896","0893-7400"],"issn-type":[{"value":"1547-1896","type":"print"},{"value":"0893-7400","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,24]]}}}