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Treatment should focus on neonatal feeding and growth, followed by hormonal therapy for hypothalamic dysfunction, and should then be directed at the prevention and treatment of obesity and obesity-related complications. Effective treatment requires a comprehensive multidisciplinary approach.<\/jats:p>","DOI":"10.1097\/01.jaa.0000000000000079","type":"journal-article","created":{"date-parts":[[2025,1,23]],"date-time":"2025-01-23T09:00:14Z","timestamp":1737622814000},"page":"e1-e6","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["A review of Prader-Willi syndrome"],"prefix":"10.1097","volume":"38","author":[{"given":"Seth","family":"Metzler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gina R.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,23]]},"reference":[{"issue":"1","key":"R1-20250123","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/gim.0b013e31822bead0","article-title":"Prader-Willi 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