{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:49:46Z","timestamp":1783691386655,"version":"3.55.0"},"reference-count":13,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T00:00:00Z","timestamp":1230854400000},"content-version":"vor","delay-in-days":946,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2006,6]]},"abstract":"Abstract<\/jats:title>Educational Objective:<\/jats:bold> Discuss potential patterns in the epidemiology of infectious disease of the head and neck.<\/jats:p>Study Objectives:<\/jats:bold> To investigate patterns in the epidemiology of severe head and neck infections that may reflect the impact of host factors.<\/jats:p>Study Design:<\/jats:bold> Population\u2010based, historic cohort study.<\/jats:p>Methods:<\/jats:bold> Information on 1,010, incident head and neck infections occurring over a 5\u2010year period was reviewed for demographics, location, and time of year. A nonparametric Kruskal\u2010Wallis test was used to identify significant differences in the age distributions among the diagnosis groups. A Bonferroni, pair\u2010wise comparison procedure was used for comparison of the average age of first onset of severe head and neck infections. Chi\u2010square test was used to identify any significant association between season of the year and disease.<\/jats:p>Results:<\/jats:bold> Significant differences were identified in the age distributions among the diagnosis groups (P<\/jats:italic> < .001). The average age of first onset of cellulitis of the neck and retropharyngeal abscess is earlier than peritonsillar abscess, at 2 to 3 years and 13 years, respectively. Parapharyngeal and periapical abscesses and cellulitis of the face occur at approximately age 6. The incidence of parapharyngeal abscess and diseases of the pharynx is decreased during Spring, whereas peritonsillar abscesses and acute periodontitis occurs more often in Spring and Summer. Age does not appear to be related to season of first occurrence.<\/jats:p>Conclusions:<\/jats:bold> Head and neck infections are not random occurrences based on exposure alone; host factors are clearly important. Given the lack of correlation with school age, the results cannot be explained on the basis of exposure alone. Developmental patterns of the host immune response may be related to the age differential identified in the current study and are cause for further investigation.<\/jats:p>","DOI":"10.1097\/01.mlg.0000217526.19167.c9","type":"journal-article","created":{"date-parts":[[2006,6,1]],"date-time":"2006-06-01T12:25:41Z","timestamp":1149164741000},"page":"887-889","source":"Crossref","is-referenced-by-count":22,"title":["Demographics of Pediatric Head and Neck Infections in a Tertiary Care Hospital"],"prefix":"10.1002","volume":"116","author":[{"given":"John M.","family":"Schweinfurth","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"e_1_2_7_2_2","first-page":"199","article-title":"Peritonsillar abscess associated with infectious mononucleosis: retrospective study of three cases.","volume":"107","author":"Hatanaka A","year":"2004","journal-title":"J Otol Rhinol Laryngol Soc Japan"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949810701213"},{"key":"e_1_2_7_4_2","article-title":"Reported adverse events temporally associated with vaccine administration in Canada: 1993 to 1997","volume":"4","author":"Public Health Agency of Canada","year":"1999","journal-title":"Paediatr Child Health"},{"key":"e_1_2_7_5_2","first-page":"1700","volume-title":"Otolaryngology\u2010Otolaryngology Head Neck Surgery","author":"Weed HG","year":"1998"},{"key":"e_1_2_7_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70270-9"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.131.5.383"},{"key":"e_1_2_7_8_2","first-page":"1547","volume-title":"Textbook of Pediatric Infectious Diseases","author":"Sumaya CV","year":"1992"},{"key":"e_1_2_7_9_2","first-page":"1525","volume-title":"Pediatric Otolaryngology","author":"Yellon RF","year":"1996"},{"key":"e_1_2_7_10_2","first-page":"738","volume-title":"Head and Neck Surgery\u2010Otolaryngology","author":"Scott BA","year":"1993"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2005.02799.x"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.170.4.1958"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.3.1483"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.2003.02390.x"}],"container-title":["The Laryngoscope"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1097%2F01.MLG.0000217526.19167.C9","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1097\/01.MLG.0000217526.19167.C9","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T09:45:19Z","timestamp":1700041519000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1097\/01.MLG.0000217526.19167.C9"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,6]]},"references-count":13,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2006,6]]}},"alternative-id":["10.1097\/01.MLG.0000217526.19167.C9"],"URL":"https:\/\/doi.org\/10.1097\/01.mlg.0000217526.19167.c9","archive":["Portico"],"relation":{},"ISSN":["0023-852X","1531-4995"],"issn-type":[{"value":"0023-852X","type":"print"},{"value":"1531-4995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,6]]}}}