{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:04:29Z","timestamp":1786118669726,"version":"build-2736575974"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2007,6]]},"DOI":"10.1097\/01.pas.0000213441.86030.fc","type":"journal-article","created":{"date-parts":[[2007,5,22]],"date-time":"2007-05-22T20:58:53Z","timestamp":1179867533000},"page":"919-925","source":"Crossref","is-referenced-by-count":52,"title":["Role of Human Papillomavirus in Squamous Cell Metaplasia-Dysplasia-Carcinoma of the Rectum"],"prefix":"10.1097","volume":"31","author":[{"given":"Christina S.","family":"Kong","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark L.","family":"Welton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teri A.","family":"Longacre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20210131","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1007\/BF02553732","article-title":"Squamous-cell metaplasia with severe dysplasia of the colonic mucosa in ulcerative colitis. Report of a case","volume":"31","author":"Adamsen","year":"1988","journal-title":"Dis Colon Rectum"},{"key":"R2-14-20210131","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0016-5085(19)35241-2","article-title":"Carcinoma and ulcerative colitis: prognosis","volume":"39","author":"Bargen","year":"1960","journal-title":"Gastroenterology"},{"key":"R3-14-20210131","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1136\/jcp.55.4.244","article-title":"The causal relation between human papillomavirus and cervical cancer","volume":"55","author":"Bosch","year":"2002","journal-title":"J Clin Pathol"},{"key":"R4-14-20210131","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1002\/1097-0142(1971)28:5<1111::AID-CNCR2820280504>3.0.CO;2-V","article-title":"Primary squamous cell carcinoma and adenocanthoma of the colon","volume":"28","author":"Comer","year":"1971","journal-title":"Cancer"},{"key":"R5-14-20210131","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1097\/00002030-199511000-00007","article-title":"Prospective study of high grade anal squamous intraepithelial neoplasia in a cohort of homosexual men: influence of HIV infection, immunosuppression and human papillomavirus infection","volume":"9","author":"Critchlow","year":"1995","journal-title":"AIDS"},{"key":"R6-14-20210131","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1002\/cncr.21711","article-title":"Immunoreactivity of p16 in anal cytology specimens: histologic correlation","volume":"108","author":"Darvishian","year":"2006","journal-title":"Cancer"},{"key":"R7-14-20210131","doi-asserted-by":"crossref","first-page":"10002","DOI":"10.1073\/pnas.170093297","article-title":"The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle","volume":"97","author":"Duensing","year":"2000","journal-title":"Proc Natl Acad Sci USA"},{"key":"R8-14-20210131","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/path.1700700118","article-title":"Squamous-cell carcinoma of the ascending colon","volume":"70","author":"Hicks","year":"1955","journal-title":"J Pathol Bacteriol"},{"key":"R9-14-20210131","first-page":"249","article-title":"Squamous cell carcinoma of the rectum complicating ulcerative colitis: report of two cases","volume":"39","author":"Hohm","year":"1964","journal-title":"Mayo Clin Proc"},{"key":"R10-14-20210131","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1097\/00000478-200403000-00009","article-title":"Cytomegalovirus infection in steroid-refractory ulcerative colitis: a case-control study","volume":"28","author":"Kambham","year":"2004","journal-title":"Am J Surg Pathol"},{"key":"R11-14-20210131","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/BF02587186","article-title":"Epidermoid carcinoma of the anorectum: review of 31 cases","volume":"20","author":"Kapur","year":"1977","journal-title":"Dis Colon Rectum"},{"key":"R12-14-20210131","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/01.pas.0000213347.65014.ee","article-title":"p16INK4A immunohistochemistry is superior to HPV in situ hybridization for the detection of high-risk HPV in atypical squamous metaplasia","volume":"31","author":"Kong","year":"2007","journal-title":"Am J Surg Pathol"},{"key":"R13-14-20210131","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1002\/jso.2930590113","article-title":"Squamous cell carcinoma complicating idiopathic inflammatory bowel disease","volume":"59","author":"Kulaylat","year":"1995","journal-title":"J Surg Oncol"},{"key":"R14-14-20210131","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1007\/BF02554319","article-title":"Primary squamous carcinoma of the rectum. Report of a case and review of the literature","volume":"28","author":"Lafreniere","year":"1985","journal-title":"Dis Colon Rectum"},{"key":"R15-14-20210131","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1097\/01.MP.0000077417.08371.CE","article-title":"Expression of p16, Rb, and p53 proteins in squamous cell carcinomas of the anorectal region harboring human papillomavirus DNA","volume":"16","author":"Lu","year":"2003","journal-title":"Mod Pathol"},{"key":"R16-14-20210131","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/BF02562498","article-title":"Primary squamous carcinoma of the proximal large bowel. Report of a case and review of the literature","volume":"26","author":"Lyttle","year":"1983","journal-title":"Dis Colon Rectum"},{"key":"R17-14-20210131","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S0016-5107(90)70929-7","article-title":"Squamous cell metaplasia without dysplasia of the colonic mucosa in ulcerative colitis","volume":"36","author":"Maruoka","year":"1990","journal-title":"Gastrointest Endosc"},{"key":"R18-14-20210131","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1016\/0140-6736(91)91233-K","article-title":"Aetiological parallel between anal cancer and cervical cancer","volume":"338","author":"Melbye","year":"1991","journal-title":"Lancet"},{"key":"R19-14-20210131","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1007\/BF02552552","article-title":"Squamous-cell carcinoma of the colon. Experience at the University of Chicago, review of the literature, report of two cases","volume":"31","author":"Michelassi","year":"1988","journal-title":"Dis Colon Rectum"},{"key":"R20-14-20210131","first-page":"77","article-title":"Primary squamous cell carcinoma of the rectosigmoid portion of the colon","volume":"84","author":"Minkowitz","year":"1967","journal-title":"Arch Pathol"},{"key":"R21-14-20210131","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3949\/ccjm.52.2.257","article-title":"Squamous cell carcinoma of the rectal stump in a patient with ulcerative colitis. Report of a case and review of the literature","volume":"52","author":"Mir-Madjlessi","year":"1985","journal-title":"Cleve Clin Q"},{"key":"R22-14-20210131","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1002\/bjs.1800550409","article-title":"Squamous-cell carcinoma of the caecum following ovarian adenocarcinoma","volume":"55","author":"Pemberton","year":"1968","journal-title":"Br J Surg"},{"key":"R23-14-20210131","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/BF02553663","article-title":"Primary squamous-cell carcinoma of the cecum and ascending colon: report of a case and review of the literature","volume":"25","author":"Pittella","year":"1982","journal-title":"Dis Colon Rectum"},{"key":"R24-14-20210131","first-page":"474","article-title":"Squamous cell carcinoma of the anus, anal canal, and rectum in 109 patients","volume":"114","author":"Richards","year":"1962","journal-title":"Surg Gynecol Obstet"},{"key":"R25-14-20210131","doi-asserted-by":"crossref","first-page":"1030","DOI":"10.1053\/j.gastro.2005.12.035","article-title":"Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis","volume":"130","author":"Rutter","year":"2006","journal-title":"Gastroenterology"},{"key":"R26-14-20210131","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1097\/01.pgp.0000130108.03231.89","article-title":"Immunohistochemical staining for p16 and p53 in premalignant and malignant epithelial lesions of the vulva","volume":"23","author":"Santos","year":"2004","journal-title":"Int J Gynecol Pathol"},{"key":"R27-14-20210131","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1053\/gast.2001.22523","article-title":"Human papillomavirus type 16-associated primary squamous cell carcinoma of the rectum","volume":"120","author":"Sotlar","year":"2001","journal-title":"Gastroenterology"},{"key":"R28-14-20210131","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/BF02560169","article-title":"Squamous-cell carcinoma of the colon and rectum","volume":"26","author":"Vezeridis","year":"1983","journal-title":"Dis Colon Rectum"},{"key":"R29-14-20210131","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1002\/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F","article-title":"Human papillomavirus is a necessary cause of invasive cervical cancer worldwide","volume":"189","author":"Walboomers","year":"1999","journal-title":"J Pathol"},{"key":"R30-14-20210131","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.soc.2003.12.005","article-title":"The etiology and epidemiology of anal cancer","volume":"13","author":"Welton","year":"2004","journal-title":"Surg Oncol Clin N Am"},{"key":"R31-14-20210131","first-page":"48","article-title":"Squamous carcinoma with schistosomiasis of the colon","volume":"37","author":"Wiener","year":"1962","journal-title":"Am J Gastroenterol"},{"key":"R32-14-20210131","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/path.1711290306","article-title":"Squamous carcinoma of the colorectum and its genesis","volume":"129","author":"Williams","year":"1979","journal-title":"J Pathol"},{"key":"R33-14-20210131","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1007\/BF02618400","article-title":"Squamous cell carcinoma of the rectum: report of a case complicating chronic ulcerative colitis","volume":"127","author":"Zirkin","year":"1963","journal-title":"Dis Colon Rectum"}],"container-title":["American Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00000478-200706000-00014","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:40:14Z","timestamp":1786034414000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00000478-200706000-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":33,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007]]}},"URL":"https:\/\/doi.org\/10.1097\/01.pas.0000213441.86030.fc","relation":{},"ISSN":["0147-5185"],"issn-type":[{"value":"0147-5185","type":"print"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}