{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:15:28Z","timestamp":1791191728123,"version":"4.1.0"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplantation"],"published-print":{"date-parts":[[2003,12]]},"DOI":"10.1097\/01.tp.0000081043.23751.81","type":"journal-article","created":{"date-parts":[[2003,12,11]],"date-time":"2003-12-11T04:05:54Z","timestamp":1071115554000},"page":"1623-1625","source":"Crossref","is-referenced-by-count":141,"title":["Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity?1"],"prefix":"10.1097","volume":"76","author":[{"given":"Niraj M.","family":"Desai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Goss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaoping","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan A.","family":"Wolf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileen","family":"Markmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maral","family":"Palanjian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela P.","family":"Shock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sue","family":"Feliciano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F. Charles","family":"Brunicardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clyde F.","family":"Barker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Naji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James F.","family":"Markmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1056\/NEJM200007273430401","volume":"343","author":"Shapiro","year":"2000","journal-title":"N Engl J Med"},{"key":"R2-18","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1056\/NEJM199609193351205","volume":"335","author":"Tyden","year":"1996","journal-title":"N Engl J Med"},{"key":"R3-18","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1097\/00007890-199506000-00018","volume":"59","author":"Tamura","year":"1995","journal-title":"Transplantation"},{"key":"R4-18","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/00007890-199109000-00026","volume":"52","author":"Ricordi","year":"1991","journal-title":"Transplantation"},{"key":"R5-18","first-page":"A459","volume":"51","author":"Bell","year":"2002","journal-title":"Diabetes"},{"key":"R6-18","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1038\/nm0202-128","volume":"8","author":"Guba","year":"2002","journal-title":"Nat Med"},{"key":"R7-18","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1016\/S0041-1345(97)01441-3","volume":"30","author":"Shapiro","year":"1998","journal-title":"Transplant Proc"},{"key":"R8-18","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/BF00613427","volume":"9","author":"Andersson","year":"1975","journal-title":"Eur J Clin Pharmacol"}],"container-title":["Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/01.TP.0000081043.23751.81","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T18:56:04Z","timestamp":1785783364000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00007890-200312150-00018"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2003,12]]},"references-count":8,"journal-issue":{"issue":"11"},"URL":"https:\/\/doi.org\/10.1097\/01.tp.0000081043.23751.81","relation":{},"ISSN":["0041-1337"],"issn-type":[{"value":"0041-1337","type":"print"}],"subject":[],"published":{"date-parts":[[2003,12]]}}}