{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:29:29Z","timestamp":1791178169097,"version":"4.1.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,9,15]]},"DOI":"10.1097\/01.tp.0000173382.11916.bf","type":"journal-article","created":{"date-parts":[[2005,9,21]],"date-time":"2005-09-21T04:00:49Z","timestamp":1127275249000},"page":"653-659","source":"Crossref","is-referenced-by-count":26,"title":["Regulation of Hepatocyte Engraftment and Proliferation after Cytotoxic Drug-Induced Perturbation of the Rat Liver"],"prefix":"10.1097","volume":"80","author":[{"given":"Kyung Sik","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigid","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mari","family":"Inada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20210129","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.trim.2003.12.014","article-title":"Emerging insights into liver-directed cell therapy for genetic and acquired disorders.","volume":"12","author":"Gupta","year":"2004","journal-title":"Transplant Immunol"},{"key":"R2-18-20210129","doi-asserted-by":"crossref","first-page":"5860","DOI":"10.1073\/pnas.92.13.5860","article-title":"Integration of transplanted hepatocytes in host liver plates demonstrated with dipeptidyl peptidase IV deficient rats.","volume":"92","author":"Gupta","year":"1995","journal-title":"Proc Natl Acad Sci (USA)"},{"key":"R3-18-20210129","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1002\/hep.510290213","article-title":"Entry and integration of transplanted hepatocytes in liver plates occur by disruption of hepatic sinusoidal endothelium.","volume":"29","author":"Gupta","year":"1999","journal-title":"Hepatology"},{"key":"R4-18-20210129","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/jhep.2002.33896","article-title":"Cyclophosphamide disrupts hepatic sinusoidal endothelium and improves transplanted cell engraftment in rat liver.","volume":"36","author":"Malhi","year":"2002","journal-title":"Hepatology"},{"key":"R5-18-20210129","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1053\/gast.2002.36592","article-title":"Kupffer cells participate in early clearance of syngeneic hepatocytes transplanted in the rat liver.","volume":"123","author":"Joseph","year":"2002","journal-title":"Gastroenterology"},{"key":"R6-18-20210129","doi-asserted-by":"crossref","first-page":"G631","DOI":"10.1152\/ajpgi.2000.279.3.G631","article-title":"Transplanted reporter cells help in defining onset of hepatocyte proliferation during the life of F344 rats.","volume":"279","author":"Sokhi","year":"2000","journal-title":"Am J Physiol Gastroint Liver Physiol"},{"key":"R7-18-20210129","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/S0002-9440(10)65574-5","article-title":"Long-term, near-total liver replacement by transplantation of isolated hepatocytes in rats treated with retrorsine.","volume":"153","author":"Laconi","year":"1998","journal-title":"Am J Pathol"},{"key":"R8-18-20210129","doi-asserted-by":"crossref","first-page":"1818","DOI":"10.1097\/00007890-200206150-00020","article-title":"Liver repopulation after cell transplantation in mice treated with retrorsine and carbon tetrachloride.","volume":"73","author":"Guo","year":"2002","journal-title":"Transplantation"},{"key":"R9-18-20210129","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1002\/hep.510300418","article-title":"Role of thyroid hormone in stimulating liver repopulation in the rat by transplanted hepatocytes.","volume":"30","author":"Oren","year":"1999","journal-title":"Hepatology"},{"key":"R10-18-20210129","first-page":"5871","article-title":"Amelioration of radiation-induced liver damage in partially hepatectomized rats by hepatocyte transplantation.","volume":"59","author":"Guha","year":"1999","journal-title":"Cancer Res"},{"key":"R11-18-20210129","doi-asserted-by":"crossref","first-page":"13114","DOI":"10.1073\/pnas.192365499","article-title":"Cell transplantation after oxidative hepatic preconditioning with radiation and ischemia-reperfusion leads to extensive liver repopulation.","volume":"99","author":"Malhi","year":"2002","journal-title":"Proc Natl Acad Sci USA"},{"key":"R12-18-20210129","doi-asserted-by":"crossref","first-page":"14212","DOI":"10.1073\/pnas.241509698","article-title":"The anticancer drug-DNA complex: femtosecond primary dynamics for anthracycline antibiotics function.","volume":"98","author":"Qu","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"R13-18-20210129","doi-asserted-by":"crossref","first-page":"479","DOI":"10.3727\/000000003108748009","article-title":"Detection of labile anthracycline-DNA adducts by real-time PCR.","volume":"13","author":"Spencer","year":"2003","journal-title":"Oncol Res"},{"key":"R14-18-20210129","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1111\/j.1349-7006.2003.tb01503.x","article-title":"Distinct mechanisms of site-specific oxidative DNA damage by doxorubicin in the presence of copper(II) and NADPH-cytochrome P450 reductase.","volume":"94","author":"Mizutani","year":"2003","journal-title":"Cancer Sci"},{"key":"R15-18-20210129","doi-asserted-by":"crossref","first-page":"2805","DOI":"10.1038\/sj.onc.1206366","article-title":"Caspase inhibition switches doxorubicin-induced apoptosis to senescence.","volume":"22","author":"Rebbaa","year":"2003","journal-title":"Oncogene"},{"key":"R16-18-20210129","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1093\/mutage\/17.2.141","article-title":"Comparison of camptothecin derivatives presently in clinical trials: genotoxic potency and mitotic recombination.","volume":"17","author":"Cunha","year":"2002","journal-title":"Mutagenesis"},{"key":"R17-18-20210129","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S1383-5718(02)00136-5","article-title":"Comparative genotoxic effect of vincristine, vinblastine, and vinorelbine in somatic cells of Drosophila melanogaster.","volume":"519","author":"Tiburi","year":"2002","journal-title":"Mutat Res"},{"key":"R18-18-20210129","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1042\/bj2730497","article-title":"A Fischer rat substrain deficient in dipeptidyl peptidase IV activity makes normal steady-state RNA levels and an altered protein. Use as a liver-cell transplantation model.","volume":"273","author":"Thompson","year":"1991","journal-title":"Biochem J"},{"key":"R19-18-20210129","doi-asserted-by":"crossref","first-page":"11921","DOI":"10.1021\/bi00162a035","article-title":"An active-site mutation (Gly\u2192Arg) of dipeptidyl peptidase IV causes its retention and rapid degradation in the endoplasmic reticulum.","volume":"31","author":"Tsuji","year":"1992","journal-title":"Biochem"},{"key":"R20-18-20210129","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/096368979700600404","article-title":"Analysis of hepatocyte distribution and survival in vascular beds with cells marked by 99m-Tc or endogenous dipeptidyl peptidase IV activity.","volume":"6","author":"Gupta","year":"1997","journal-title":"Cell Transplant"},{"key":"R21-18-20210129","first-page":"G1260","article-title":"Partial hepatectomy-induced polyploidy attenuates hepatocyte replication and activates cell aging events.","volume":"276","author":"Sigal","year":"1999","journal-title":"Am J Physiol"},{"key":"R22-18-20210129","first-page":"G629","article-title":"Transplanted hepatocytes proliferate differently after CCl4 treatment and hepatocyte growth factor infusion.","volume":"276","author":"Gupta","year":"1999","journal-title":"Am J Physiol"},{"key":"R23-18-20210129","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/00005344-199707000-00018","article-title":"Bioactivation of monocrotaline by P-450 3A in rat liver.","volume":"30","author":"Kasahara","year":"1997","journal-title":"J Cardiovasc Pharmacol"},{"key":"R24-18-20210129","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/exmp.2000.2308","article-title":"Induction of cytochrome P450 enzymes in the livers of rats treated with the pyrrolizidine alkaloid retrorsine.","volume":"69","author":"Gordon","year":"2000","journal-title":"Exp Mol Pathol"},{"key":"R25-18-20210129","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1016\/S0016-5085(96)70078-1","article-title":"Efficacy and safety of repeated hepatocyte transplantation for significant liver repopulation in rodents.","volume":"111","author":"Rajvanshi","year":"1996","journal-title":"Gastroenterology"},{"key":"R26-18-20210129","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1182\/blood-2003-03-0869","article-title":"Hfe deficiency increases susceptibility to cardiotoxicity and exacerbates changes in iron metabolism induced by doxorubicin.","volume":"102","author":"Miranda","year":"2003","journal-title":"Blood"},{"key":"R27-18-20210129","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3109\/08880019809009513","article-title":"Veno-occlusive disease-like hepatotoxicity in two children receiving chemotherapy for Wilms' tumor and clear cell sarcoma of kidney.","volume":"15","author":"Hazar","year":"1998","journal-title":"Pediatr Hematol Oncol"}],"container-title":["Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/01.tp.0000173382.11916.bf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T15:02:07Z","timestamp":1785855727000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00007890-200509150-00018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9,15]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.1097\/01.tp.0000173382.11916.bf","relation":{},"ISSN":["0041-1337"],"issn-type":[{"value":"0041-1337","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9,15]]}}}