{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T21:06:07Z","timestamp":1793048767035,"version":"4.5.0"},"reference-count":47,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1097\/aci.0b013e32833b280c","type":"journal-article","created":{"date-parts":[[2010,5,19]],"date-time":"2010-05-19T03:02:08Z","timestamp":1274238128000},"page":"347-353","source":"Crossref","is-referenced-by-count":98,"title":["Mastocytosis and insect venom allergy"],"prefix":"10.1097","volume":"10","author":[{"given":"Patrizia","family":"Bonadonna","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberta","family":"Zanotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ulrich","family":"M\u00fcller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-15-20210128","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0091-6749(97)70188-X","article-title":"Hymenoptera sting anaphylaxis and urticaria pigmentosa: clinical findings and results of venom immunotherapy in ten patients","volume":"100","author":"Fricker","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"R2-15-20210128","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0091-6749(97)70314-2","article-title":"Fatal anaphylaxis after a yellow jacket sting, despite venom immunotherapy, in two patients with mastocytosis","volume":"99","author":"Oude Elberink","year":"1997","journal-title":"J Allergy Clin Immunol"},{"key":"R3-15-20210128","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1097\/01.all.0000136756.20701.f8","article-title":"Mastocytosis and hymenoptera allergy","volume":"4","author":"Dubois","year":"2004","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"R4-15-20210128","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/01.all.0000235903.10548.63","article-title":"Mastocytosis and hymenoptera venom allergy","volume":"6","author":"Rueff","year":"2006","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"R5-15-20210128","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1046\/j.1365-2222.2003.01755.x","article-title":"Elevated basal serum tryptase and hymenoptera venom allergy: relation to severity of sting reactions and to safety and efficacy of venom immunotherapy","volume":"33","author":"Haeberli","year":"2003","journal-title":"Clin Exp Allergy"},{"key":"R6-15-20210128","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1159\/000083954","article-title":"Indolent systemic mastocytosis with elevated serum tryptase, absence of skin lesions, and recurrent severe anaphylactoid episodes","volume":"136","author":"Florian","year":"2005","journal-title":"Int Arch Allergy Immunol"},{"key":"R7-15-20210128","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1111\/j.1365-2222.2007.02804.x","article-title":"Prevalence of allergy and anaphylactic symptoms in 210 adult and pediatric patients with mastocytosis in Spain: a study of the Spanish network on mastocytosis (REMA)","volume":"37","author":"Gonz\u00e1lez de Olano","year":"2007","journal-title":"Clin Exp Allergy"},{"key":"R8-15-20210128","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1111\/j.1398-9995.2007.01569.x","article-title":"Anaphylaxis in patients with mastocytosis: a study on history, clinical features and risk factors in 120 patients","volume":"63","author":"Brockow","year":"2008","journal-title":"Allergy"},{"key":"R9-15-20210128","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1016\/j.jaci.2008.11.018","article-title":"Clonal mast cell disorders in patients with systemic reactions to hymenoptera stings and increased serum tryptase levels","volume":"123","author":"Bonadonna","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"R10-15-20210128","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0140-6736(00)03647-3","article-title":"Constitutively raised serum concentrations of mast-cell tryptase and severe anaphylactic reactions to hymenoptera stings","volume":"357","author":"Ludolph-Hauser","year":"2001","journal-title":"Lancet"},{"key":"R11-15-20210128","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.jaci.2009.08.027","article-title":"Predictors of severe systemic anaphylactic reactions in patients with hymenoptera venom allergy: importance of baseline serum tryptase \u2013 a study of the European Academy of Allergology and Clinical Immunology Interest Group of Insect venom hypersensitivity","volume":"129","author":"Rueff","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"R12-15-20210128","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1111\/j.1398-9995.2006.01077.x","article-title":"European Polistes venom allergy","volume":"61","author":"Severino","year":"2006","journal-title":"Allergy"},{"key":"R13-15-20210128","first-page":"1339","article-title":"Diagnosis of hymenoptera venom allergy.","volume":"60","author":"Bilo","year":"2005","journal-title":""},{"key":"R14-15-20210128","doi-asserted-by":"crossref","first-page":"1459","DOI":"10.1111\/j.1398-9995.2005.00960.x","article-title":"EAACI Interest Group on insect venom hypersensitivity: prevention and treatment of hymenoptera venom allergy: guidelines for clinical practice","volume":"60","author":"Bonifazi","year":"2005","journal-title":"Allergy"},{"key":"R15-15-20210128","doi-asserted-by":"crossref","first-page":"1622","DOI":"10.1056\/NEJM198706253162603","article-title":"Tryptase levels as an indicator of mast-cell activation in systemic anaphylaxis and mastocytosis","volume":"316","author":"Schwartz","year":"1987","journal-title":"N Engl J Med"},{"key":"R16-15-20210128","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/BF01533368","article-title":"Time course of appearance and disappearance of human mast cell tryptase: use in systemic anaphylaxis","volume":"14","author":"Schwartz","year":"1994","journal-title":"J Clin Immunol"},{"key":"R17-15-20210128","doi-asserted-by":"crossref","first-page":"3117","DOI":"10.1182\/blood.V87.8.3117.bloodjournal8783117","article-title":"A point mutation in the catalytic domain of c-Kit induces growth factor independence, tumorigenicity, and differentiation of mast cells","volume":"87","author":"Piao","year":"1996","journal-title":"Blood"},{"key":"R18-15-20210128","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1016\/S0145-2126(01)00038-8","article-title":"Diagnostic criteria and classification of mastocytosis: a consensus proposal","volume":"25","author":"Valent","year":"2001","journal-title":"Leuk Res"},{"key":"R19-15-20210128","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/j.1365-2362.2007.01807.x","article-title":"Standards and standardization in mastocytosis: consensus statements on diagnostics, treatment recommendations and response criteria","volume":"37","author":"Valent","year":"2007","journal-title":"Eur J Clin Invest"},{"key":"R20-15-20210128","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1046\/j.1365-2133.1999.02814.x","article-title":"Carter ND: lack of c-Kit mutation in familial urticaria pigmentosa","volume":"140","author":"Rosbotham","year":"1999","journal-title":"Br J Dermatol"},{"key":"R21-15-20210128","doi-asserted-by":"crossref","first-page":"61","DOI":"10.2174\/187152806775269303","article-title":"Current options in the treatment of mast cell mediator-related symptoms in mastocytosis","volume":"5","author":"Escribano","year":"2006","journal-title":"Inflamm Allergy Drug Targets"},{"key":"R22-15-20210128","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1159\/000048188","article-title":"Mastocytosis: mediator-related signs and symptoms","volume":"127","author":"Castells","year":"2002","journal-title":"Int Arch Allergy Immunol"},{"key":"R23-15-20210128","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1182\/blood-2006-06-028100","article-title":"Demonstration of an aberrant mast cell population with clonal markers in a subset of patients with \u2018idiopathic\u2019 anaphylaxis","volume":"110","author":"Akin","year":"2007","journal-title":"Blood"},{"key":"R24-15-20210128","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1159\/000096442","article-title":"Diagnostic and subdiagnostic accumulation of mast cells in the bone marrow of patients with anaphylaxis: monoclonal mast cell activation syndrome","volume":"142","author":"Sonneck","year":"2007","journal-title":"Int Arch Allergy Immunol"},{"key":"R25-15-20210128","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1111\/j.1398-9995.2009.02108.x","article-title":"How much specific is the association between hymenoptera venom allergy and mastocytosis?","volume":"64","author":"Bonadonna","year":"2009","journal-title":"Allergy"},{"key":"R26-15-20210128","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/0091-6749(83)90630-9","article-title":"Anaphylaxis after hymenoptera sting in three patients with urticaria pigmentosa","volume":"72","author":"M\u00fcller","year":"1983","journal-title":"J Allergy Clin Immunol"},{"key":"R27-15-20210128","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/j.1365-2796.1993.tb00984.x","article-title":"Anaphylactoid shock following hymenoptera sting as a presenting symptom of systemic mastocytosis","volume":"233","author":"Kors","year":"1993","journal-title":"J Intern Med"},{"key":"R28-15-20210128","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1046\/j.1365-2133.1999.03214.x","article-title":"Mastocytosis associated with severe wasp sting anaphylaxis detected by elevated serum mast cell tryptase levels","volume":"141","author":"Biedermann","year":"1999","journal-title":"Br J Dermatol"},{"key":"R29-15-20210128","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/0470861193.ch10","article-title":"Fatal anaphylaxis in the UK, 1992\u20132001","volume":"257","author":"Pumphrey","year":"2004","journal-title":"Novartis Found Symp"},{"key":"R30-15-20210128","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0091-6749(98)70264-7","article-title":"Sting anaphylaxis and urticaria pigmentosa","volume":"101","author":"Wein","year":"1998","journal-title":"J Allergy Clin Immunol"},{"key":"R31-15-20210128","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1111\/j.1365-2222.2009.03210.x","article-title":"Cutaneous manifestations in hymenoptera and Diptera anaphylaxis: relationship with basal serum tryptase","volume":"39","author":"Potier","year":"2009","journal-title":"Clin Exp Allergy"},{"key":"R33-15-20210128","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1111\/j.1365-2222.2009.03436.x","article-title":"Serum concentration of baseline mast cell tryptase: evidence for a decline during long-term immunotherapy for hymenoptera venom allergy","volume":"40","author":"Dugas-Breit","year":"2010","journal-title":"Clin Exp Allergy"},{"key":"R34-15-20210128","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1182\/blood-2009-10-249979","article-title":"WHO subvariants of indolent mastocytosis: clinical details and prognostic evaluation in 159 consecutive adults","volume":"115","author":"Pardanani","year":"2010","journal-title":"Blood"},{"key":"R35-15-20210128","first-page":"276","article-title":"Allergens in hymenoptera venom XII: how much protein is in a sting?","volume":"52","author":"Hofmann","year":"1984","journal-title":"Ann Allergy"},{"key":"R36-15-20210128","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1111\/j.1398-9995.1990.tb00945.x","article-title":"Mastocytosis and atopy: a study of 33 patients with urticaria pigmentosa","volume":"45","author":"M\u00fcller","year":"1990","journal-title":"Allergy"},{"key":"R37-15-20210128","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1007\/s11882-009-0010-9","article-title":"The problem of anaphylaxis and mastocytosis","volume":"9","author":"M\u00fcller","year":"2009","journal-title":"Curr Allergy Asthma Rep"},{"key":"R38-15-20210128","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.jaci.2007.11.010","article-title":"Safety and effectiveness of immunotherapy in patients with indolent systemic mastocytosis presenting with hymenoptera venom anaphylaxis","volume":"121","author":"Gonz\u00e1lez de Olano","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"R39-15-20210128","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/j.jaci.2009.02.003","article-title":"Assessing anaphylactic risk? Consider mast cell clonality","volume":"123","author":"Metcalfe","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"R40-15-20210128","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1111\/j.1398-9995.2009.02118.x","article-title":"Mastocytosis and insect venom allergy: diagnosis, safety and efficacy of venom immunotherapy","volume":"64","author":"Niedoszytko","year":"2009","journal-title":"Allergy"},{"key":"R41-15-20210128","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/0091-6749(94)90213-5","article-title":"Rush hymenoptera venom immunotherapy: successful treatment in a patient with systemic mast cell disease","volume":"94","author":"Engler","year":"1994","journal-title":"J Allergy Clin Immunol"},{"key":"R42-15-20210128","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.jaci.2007.10.014","article-title":"Allergen specific immunotherapy is safe and effective in patients with mastocytosis and hymenoptera allergy","volume":"121","author":"Bonadonna","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"R43-15-20210128","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1034\/j.1398-9995.2000.00520.x","article-title":"Reduction of side-effects from ultrarush immunotherapy with honeybee venom by pretreatment with fexofenadine: a double-blind, placebo-controlled trial","volume":"55","author":"Reimers","year":"2000","journal-title":"Allergy"},{"key":"R45-15-20210128","first-page":"484","article-title":"High omalizumab dose controls recurrent reactions to venom immuno-therapy in indolent systemic mastocytosis","volume":"55","author":"Kontou-Fili","year":"2008","journal-title":"Allergy"},{"key":"R46-15-20210128","first-page":"36","article-title":"Mosbech H, editors. Position paper: immunotherapy with hymenoptera venoms. EAACI Subcommittee on Insect Venom Allergy.","volume":"48","author":"Muller","year":"1993","journal-title":"Allergy"},{"key":"R47-15-20210128","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/ACI.0b013e3282f1eca5","article-title":"Advances in hymenoptera venom immunotherapy","volume":"7","author":"Bil\u00f2","year":"2007","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"R48-15-20210128","first-page":"S14","article-title":"Fatal outcome of a Vespula sting in a patient with mastocytosis after specific immunotherapy with honey bee venom","volume":"135","author":"Reimers","year":"2005","journal-title":"Swiss Med Wkly"},{"key":"R49-15-20210128","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1159\/000113520","article-title":"Fatal anaphylactic sting reaction in a patient with mastocytosis","volume":"146","author":"Wagner","year":"2008","journal-title":"Int Arch Allergy Immunol"}],"container-title":["Current Opinion in Allergy & Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/ACI.0b013e32833b280c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:21:54Z","timestamp":1786040514000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00130832-201008000-00015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":47,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/aci.0b013e32833b280c","relation":{},"ISSN":["1528-4050"],"issn-type":[{"value":"1528-4050","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}