{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:08:43Z","timestamp":1790687323930,"version":"4.1.0"},"reference-count":46,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1097\/aci.0b013e32835c16b6","type":"journal-article","created":{"date-parts":[[2012,12,7]],"date-time":"2012-12-07T12:16:56Z","timestamp":1354882616000},"page":"78-86","source":"Crossref","is-referenced-by-count":76,"title":["Asthma and comorbidities"],"prefix":"10.1097","volume":"13","author":[{"given":"Dennis K.","family":"Ledford","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard F.","family":"Lockey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-14-20210128","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1183\/09059180.00002110","article-title":"Update on asthma control in five European countries: results of a 2008 survey.","volume":"19","author":"Demoly","year":"2010","journal-title":"Eur Respir Rev"},{"key":"R2-14-20210128","doi-asserted-by":"crossref","first-page":"529","DOI":"10.2500\/aap.2009.30.3276","article-title":"The status of asthma control in the U.S. adult population.","volume":"30","author":"Fuhlbrigge","year":"2009","journal-title":"Allergy Asthma Proc"},{"key":"R3-14-20210128","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1183\/09031936.00121308","article-title":"Influence of comorbid conditions on asthma.","volume":"33","author":"Boulet","year":"2009","journal-title":"Eur Respir J"},{"key":"R4-14-20210128","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1586\/1744666X.4.6.731","article-title":"Impact of co-morbidities on asthma.","volume":"4","author":"Thomas","year":"2008","journal-title":"Expert Rev Clin Immunol"},{"key":"R5-14-20210128","doi-asserted-by":"crossref","first-page":"812","DOI":"10.1183\/09031936.05.00037905","article-title":"Risk factors of frequent exacerbations in difficult-to-treat asthma.","volume":"26","author":"ten Brinke","year":"2007","journal-title":"Eur Respir J"},{"key":"R6-14-20210128","doi-asserted-by":"crossref","first-page":"e34967","DOI":"10.1371\/journal.pone.0034967","article-title":"Describing and quantifying asthma comorbidity: a population study.","volume":"7","author":"Gershon","year":"2012","journal-title":"Plos One"},{"key":"R7-14-20210128","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1067\/mai.2001.111593","article-title":"Rhinosinusitis in severe asthma.","volume":"107","author":"Bresciani","year":"2001","journal-title":"J Allergy Clin Immunol"},{"issue":"Suppl 86","key":"R8-14-20210128","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1398-9995.2007.01620.x","article-title":"Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2) LEN and Allergen).","volume":"63","author":"Bousquet","year":"2008","journal-title":"Allergy"},{"key":"R9-14-20210128","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/j.1440-1843.2006.00964.x","article-title":"Nasal polyps and the severity of asthma.","volume":"12","author":"Ceylan","year":"2007","journal-title":"Respirology"},{"key":"R10-14-20210128","first-page":"A198","article-title":"Asthma control and airway obstruction in asthmatic patients with versus without polypoid rhinitis.","volume":"175","author":"Bilodeau","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"R11-14-20210128","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/S0140-6736(08)61446-4","article-title":"Rhinitis and onset of asthma: a longitudinal population-based study.","volume":"372","author":"Shaaban","year":"2008","journal-title":"Lancet"},{"key":"R12-14-20210128","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1164\/ajrccm.161.6.9906121","article-title":"Segmental bronchial provocation induces nasal inflammation in allergic rhinitis patients.","volume":"161","author":"Braunstahl","year":"2000","journal-title":"Am J Respir Crit Care Med"},{"key":"R13-14-20210128","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1067\/mai.2001.113046","article-title":"Nasal allergen provocation induces adhesion molecule expression and tissue eosinophilia in upper and lower airways.","volume":"107","author":"Braunstahl","year":"2001","journal-title":"J Allergy Clin Immunol"},{"key":"R15-14-20210128","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1136\/gut.2007.122465","article-title":"The association between gastro-oesophageal reflux disease and asthma: a systematic review.","volume":"56","author":"Havemann","year":"2007","journal-title":"Gut"},{"key":"R16-14-20210128","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1164\/ajrccm.164.1.2006002","article-title":"Prevalence of upper respiratory symptoms in patients with symptomatic gastroesophageal reflux disease.","volume":"164","author":"Theodoropoulos","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"key":"R17-14-20210128","doi-asserted-by":"crossref","first-page":"1487","DOI":"10.1056\/NEJMoa0806290","article-title":"American Lung Association Asthma Clinical Research CentersThis study assessed the efficacy of esomeprazole for treatment of poorly controlled asthma.","volume":"360","author":"Mastronarde","year":"2009","journal-title":"N Engl J Med"},{"key":"R18-14-20210128","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1001\/jama.2011.2035","article-title":"Writing Committee for the American Lung Association Asthma Clinical Research CentersLansoprazole for children with poorly controlled asthma: a randomized controlled trial.","volume":"307","author":"Holbrook","year":"2012","journal-title":"JAMA"},{"key":"R19-14-20210128","doi-asserted-by":"crossref","first-page":"1128","DOI":"10.1378\/chest.128.3.1128","article-title":"2nd, et al. Lansoprazole Asthma Study GroupEffects of 24 weeks of lansoprazole therapy on asthma symptoms, exacerbations, quality of life and pulmonary function in adult asthmatic patients with acid reflux symptoms.","volume":"128","author":"Littner","year":"2005","journal-title":"Chest"},{"key":"R20-14-20210128","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0002-9343(97)89514-9","article-title":"Asthma and gastroesophageal reflux: acid suppressive therapy improves asthma outcome.","volume":"100","author":"Harding","year":"1996","journal-title":"Am J Med"},{"key":"R22-14-20210128","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.jaci.2010.10.038","article-title":"Chronic cough and irritable larynx.","volume":"127","author":"Bucca","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"R23-14-20210128","first-page":"467","article-title":"Clinical and lung-function variables associated with vocal cord dysfunction.","volume":"54","author":"Watson","year":"2009","journal-title":"Respir Care"},{"key":"R24-14-20210128","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1097\/MLG.0b013e31815ed13a","article-title":"Formal psychological testing in patients with paradoxical vocal fold dysfunction.","volume":"118","author":"Husein","year":"2008","journal-title":"Laryngoscope"},{"key":"R25-14-20210128","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.jaci.2011.06.004","article-title":"Tiotropium is noninferior to salmeterol in maintaining improved lung function in B16-ArgArg patients with asthma.","volume":"128","author":"Bateman","year":"2011","journal-title":"J Allergy Clin Immunol"},{"key":"R26-14-20210128","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1056\/NEJMoa1008770","article-title":"National Heart, Lung, and Blood Institue Asthma Clinical Research NetworkTiotropium bromide step-up therapy for adults with uncontrolled asthma.","volume":"363","author":"Peters","year":"2010","journal-title":"N Engl J Med"},{"key":"R27-14-20210128","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1586\/ers.12.27","article-title":"Efficacy of anticholinergic drugs in asthma.","volume":"6","author":"Novelli","year":"2012","journal-title":"Expert Rev Respir Med"},{"key":"R28-14-20210128","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1056\/NEJMoa1208606","article-title":"Tiotropium in asthma poorly controlled with standard combination therapy.","volume":"367","author":"Kerstjens","year":"2012","journal-title":"N Engl J Med"},{"key":"R29-14-20210128","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1016\/j.jaci.2008.03.004","article-title":"Obesity and asthma: possible mechanisms.","volume":"121","author":"Shore","year":"2008","journal-title":"J Allergy Clin Immunol"},{"key":"R30-14-20210128","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1378\/chest.09-2491","article-title":"A comparison of obese and nonobese people with asthma: exploring an asthma-obesity interaction.","volume":"137","author":"Pakhale","year":"2010","journal-title":"Chest"},{"key":"R31-14-20210128","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1186\/1471-2458-9-88","article-title":"The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-analysis.","volume":"9","author":"Guh","year":"2009","journal-title":"BMC Public Health"},{"key":"R32-14-20210128","first-page":"317","article-title":"Obesity and asthma: a specific phenotype C","volume":"134","author":"Lessard","year":"2008","journal-title":"hest"},{"key":"R33-14-20210128","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1136\/thx.2007.082784","article-title":"Body mass index and asthma severity in the National Asthma Survey.","volume":"63","author":"Taylor","year":"2008","journal-title":"Thorax"},{"key":"R34-14-20210128","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1164\/rccm.200801-076OC","article-title":"Body mass and glucocorticoid response in asthma.","volume":"178","author":"Sutherland","year":"2008","journal-title":"Am J Respir Crit Care Med"},{"key":"R35-14-20210128","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1111\/j.1440-1843.2011.02080.x","article-title":"Asthma and obesity: a known association but unknown mechanism.","volume":"17","author":"Farah","year":"2012","journal-title":"Respirology"},{"key":"R36-14-20210128","doi-asserted-by":"crossref","first-page":"1121","DOI":"10.1503\/cmaj.081332","article-title":"Over diagnosis of asthma in obese and nonobese adults.","volume":"179","author":"Aaron","year":"2008","journal-title":"CMAJ"},{"key":"R37-14-20210128","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1080\/02770900802712963","article-title":"Body mass index-percentile and diagnostic accuracy of childhood asthma.","volume":"46","author":"Lang","year":"2009","journal-title":"J Asthma"},{"key":"R38-14-20210128","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1378\/chest.11-0948","article-title":"Risk of misdiagnosis, health-related quality of life, and BMI in patients who are overweight with doctor-diagnosed asthma.","volume":"141","author":"Scott","year":"2012","journal-title":"Chest"},{"key":"R39-14-20210128","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1136\/thx.2007.086470","article-title":"Weight loss and asthma: a systematic review.","volume":"63","author":"Eneli","year":"2008","journal-title":"Thorax"},{"key":"R40-14-20210128","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.rmed.2007.07.029","article-title":"Weight loss and asthma control in severely obese asthmatic females.","volume":"102","author":"Maniscalco","year":"2008","journal-title":"Respir Med"},{"key":"R42-14-20210128","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.3109\/02770903.2011.631238","article-title":"Relationship between current psychological symptoms and future risk of asthma outcomes: a 12-month prospective cohort study.","volume":"48","author":"Wang","year":"2011","journal-title":"J Asthma"},{"key":"R43-14-20210128","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1186\/1471-244X-11-128","article-title":"Comorbidity of asthma with ADHD.","volume":"11","author":"Fasmer","year":"2011","journal-title":"BMC Psychiatry"},{"key":"R46-14-20210128","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1093\/aje\/kwk026","article-title":"Association between lung function and mental health problems among adults in the United States: findings from the First National Health and Nutrition Examination Survey.","volume":"165","author":"Goodwin","year":"2006","journal-title":"Am J Epidemiol"},{"key":"R47-14-20210128","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pec.2010.03.011","article-title":"Psychological characteristics associated with the onset and course of asthma in children and adolescents: a systematic review of longitudinal effects.","volume":"82","author":"Tibosch","year":"2011","journal-title":"Patient Educ Couns"},{"key":"R49-14-20210128","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/j.rmed.2005.02.013","article-title":"Prevalence of psychiatric morbidity in a difficult asthma population: relationship to asthma outcome.","volume":"99","author":"Heaney","year":"2005","journal-title":"Respir Med"},{"key":"R50-14-20210128","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jaci.2009.11.005","article-title":"Social stress and asthma: the role of corticosteroid insensitivity.","volume":"125","author":"Jaczku","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"R52-14-20210128","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jpsychores.2009.06.005","article-title":"Asthma and mental disorders in Canada: impact on functional impairment and mental health service use.","volume":"68","author":"Goodwein","year":"2010","journal-title":"J Psychosom Res"},{"key":"R53-14-20210128","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/ppul.20464","article-title":"A systematic review of psychological interventions for children with asthma.","volume":"42","author":"Yorke","year":"2007","journal-title":"Pediatr Pulmonol"}],"container-title":["Current Opinion in Allergy & Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/ACI.0b013e32835c16b6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,10]],"date-time":"2021-11-10T16:51:26Z","timestamp":1636563086000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00130832-201302000-00014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/aci.0b013e32835c16b6","relation":{},"ISSN":["1528-4050"],"issn-type":[{"value":"1528-4050","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}