{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T07:19:54Z","timestamp":1768288794151,"version":"3.49.0"},"reference-count":55,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,12]]},"DOI":"10.1097\/adm.0b013e31826bd76c","type":"journal-article","created":{"date-parts":[[2012,9,26]],"date-time":"2012-09-26T16:40:05Z","timestamp":1348677605000},"page":"304-310","source":"Crossref","is-referenced-by-count":11,"title":["Heroin Dependence Duration Influences the Metabolic Parameters"],"prefix":"10.1097","volume":"6","author":[{"given":"Zanina","family":"Pereska","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cvetanka","family":"Bozinovska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cedo","family":"Dimitrovski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koco","family":"Cakalarovski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andon","family":"Chibishev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Milka","family":"Zdravkovska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Babulovska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Janicevic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-11-20210126","doi-asserted-by":"crossref","first-page":"9047","DOI":"10.1074\/jbc.275.12.9047","article-title":"The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307).","volume":"275","author":"Aguirre","year":"2000","journal-title":"J Biol Chem"},{"issue":"9491","key":"R2-11-20210126","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/S0140-6736(05)67402-8","article-title":"The metabolic syndromea new worldwide definition.","volume":"366","author":"Alberti","year":"2005","journal-title":"Lancet"},{"key":"R3-11-20210126","doi-asserted-by":"crossref","first-page":"57","DOI":"10.2337\/diacare.23.1.57","article-title":"Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity.","volume":"23","author":"Bonora","year":"2000","journal-title":"Diabetes Care"},{"issue":"5-6","key":"R4-11-20210126","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1159\/000117565","article-title":"Glucoseinsulin metabolism in heroin addicts.","volume":"2","author":"Brambilla","year":"1976","journal-title":"Neuropsychobiologia"},{"issue":"4","key":"R5-11-20210126","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1520\/JFS15456J","article-title":"GCMS determination of pyrolysis products from diacetilmorphine and adulterans of street heroin camples.","volume":"47","author":"Brenneisen","year":"2002","journal-title":"J Forensic Sci"},{"key":"R6-11-20210126","first-page":"684","article-title":"The effect of bronchitis, smoking and occupation on ventilation.","volume":"87","author":"Brinkman","year":"1964","journal-title":"Ann Rev Respir Dis"},{"issue":"9","key":"R7-11-20210126","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1055\/s-2007-1011844","article-title":"Impaired glucose metabolism in heroin and methadone users.","volume":"19","author":"Ceriello","year":"1987","journal-title":"Horm Metb Res"},{"issue":"2","key":"R8-11-20210126","first-page":"117","article-title":"Insulin action and the insulin signaling network.","volume":"16","author":"Cheatham","year":"1995","journal-title":"Endocr Rev"},{"issue":"4","key":"R9-11-20210126","first-page":"463","article-title":"Chronic intermittent hypoxia from pedo-stage decreases glucose transporter 4 expression in adipose tissue and causes insulin resistance.","volume":"123","author":"Chen","year":"2010","journal-title":"Chin Med J"},{"key":"R10-11-20210126","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1007\/s00125-003-1074-z","article-title":"Relationship of adiponectin to body fat distribution, insulin sensitivity and plasma lipoproteins: evidence for independent roles of age and sex.","volume":"46","author":"Cnop","year":"2003","journal-title":"Diabetologia"},{"issue":"2","key":"R11-11-20210126","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1111\/j.1365-2036.2005.02604.x","article-title":"Concluding remarks: metabolic syndrome, liver and HCV.","volume":"22","author":"Cortez-Pinto","year":"2005","journal-title":"Aliment Pharmacol Ther"},{"issue":"3","key":"R12-11-20210126","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1097\/01.pra.0000351884.83377.e2","article-title":"Benefits of retention in methadone maintenance and chronic medical conditions as risk factors for premature death among older heroin addicts.","volume":"15","author":"Fareed","year":"2009","journal-title":"J Psychiatr Pract"},{"issue":"7","key":"R13-11-20210126","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1001\/archneur.62.7.1067","article-title":"Insulin resistance in cognitive impairment: the InCHIANTI study.","volume":"62","author":"Geroldi","year":"2005","journal-title":"Arch Neurol"},{"issue":"1","key":"R14-11-20210126","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.pnpbp.2003.09.029","article-title":"Aggressive responding in abstinent heroin addicts: neuroendocrine and personality correlates.","volume":"28","author":"Gerra","year":"2004","journal-title":"Prog Neuropsychopharmacol Biol Psychiatry"},{"issue":"3","key":"R15-11-20210126","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/BF02732039","article-title":"Sodium salicylate restores the impaired insulin response to glucose and improves glucose tolerance in heroin addicts.","volume":"24","author":"Giugliano","year":"1987","journal-title":"Acta Diabetol Lat"},{"issue":"2","key":"R17-11-20210126","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1007\/BF00421864","article-title":"Effect of enkephalins and morphine on insulin secretion from isolated rat islets.","volume":"19","author":"Green","year":"1980","journal-title":"Diabetologia"},{"issue":"4","key":"R18-11-20210126","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0361-9230(95)00104-M","article-title":"Modulation of metabolic effects of morphine-6-glucuronide by morphine-3-glucuronide.","volume":"38","author":"Hashiguchi","year":"1995","journal-title":"Brain Res Bull"},{"issue":"1","key":"R19-11-20210126","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1046\/j.1365-2249.2003.02103.x","article-title":"Augmented production of proinflammatory cytokines and accelerated allotransplantation reactions in heroin-treated mice.","volume":"132","author":"Holan","year":"2003","journal-title":"Clin Exp Immunol"},{"issue":"1","key":"R20-11-20210126","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1124\/jpet.300.1.213","article-title":"Rapid elevation of plasma interleukin-6 by morphine is dependent on autonomic stimulation of adrenal gland.","volume":"300","author":"Houghtling","year":"2002","journal-title":"J Pharmacol Exp Ther"},{"key":"R21-11-20210126","doi-asserted-by":"crossref","first-page":"73","DOI":"10.33549\/physiolres.930568","article-title":"Adipocyte-derived hormones in heroin addicts: the influence of methadone maintenance treatment.","volume":"54","author":"Housova","year":"2005","journal-title":"Physiol Res"},{"issue":"10","key":"R22-11-20210126","doi-asserted-by":"crossref","first-page":"1492","DOI":"10.1086\/429824","article-title":"Disorders of glucose metabolism among HIV-infected women.","volume":"40","author":"Howard","year":"2005","journal-title":"Clin Infect Dis"},{"issue":"6","key":"R23-11-20210126","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1111\/j.1468-1293.2006.00398.x","article-title":"Abnormal glucose metabolism among older men with or at-risk for HIV.","volume":"7","author":"Howard","year":"2006","journal-title":"HIV Med"},{"issue":"10","key":"R24-11-20210126","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1086\/374838","article-title":"Association of hepatitis C infection and antiretroviral use with diabetes mellitus in drug users.","volume":"36","author":"Howard","year":"2003","journal-title":"Clin Infect Dis"},{"key":"R25-11-20210126","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1038\/276190a0","article-title":"Morphine and -endorphin influence the secretion of the endocrine pancreas.","volume":"276","author":"Ipp","year":"1978","journal-title":"Nature"},{"issue":"6","key":"R26-11-20210126","first-page":"430","article-title":"Alcohol, tobacco, and drug use and the onset of type 2 diabetes among inner-city minority patients.","volume":"14","author":"Johnson","year":"2001","journal-title":"J Am Board Fam Pract"},{"key":"R27-11-20210126","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/j.1601-5215.2007.00192.x","article-title":"Heroin-dependent patients attempting and not attempting suicide: a comparison.","volume":"19","author":"Kalyoncu","year":"2007","journal-title":"Acta Neuropsychiatr"},{"issue":"2","key":"R28-11-20210126","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.metabol.2004.08.014","article-title":"Limitation of the validity of the homeostasis model assessment as an index of insulin resistance in Korea.","volume":"54","author":"Kang","year":"2005","journal-title":"Metabolism"},{"issue":"5","key":"R29-11-20210126","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1023\/A:1007016329300","article-title":"Morphine stimulates mesangial cell TNF- and nitrite production.","volume":"24","author":"Kapasi","year":"2000","journal-title":"Inflammation"},{"issue":"2","key":"R30-11-20210126","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0196-9781(91)90004-9","article-title":"Dual action of -endorphin on insulin release in genetically obese and lean mice.","volume":"12","author":"Khawaja","year":"1991","journal-title":"Peptides"},{"key":"R31-11-20210126","doi-asserted-by":"crossref","first-page":"588","DOI":"10.2337\/diacare.24.3.588","article-title":"Recent advances in our understanding of insulin action and insulin resistance.","volume":"24","author":"Le Roith","year":"2001","journal-title":"Diabetes Care"},{"key":"R32-11-20210126","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1093\/ajcn\/87.5.1254","article-title":"Caffeinated coffee consumption impairs blood glucose homeostasis in response to high et low glycemic index meals in healthy men.","volume":"87","author":"Lesley","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"R33-11-20210126","doi-asserted-by":"crossref","first-page":"6255","DOI":"10.1128\/MCB.23.17.6255-6266.2003","article-title":"Morphine induces desensitization of insulin receptor signaling.","volume":"17","author":"Li","year":"2003","journal-title":"Mol Cell Biol"},{"issue":"7","key":"R34-11-20210126","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1111\/j.1742-4658.2009.06938.x","article-title":"Chronic high-dose morphine treatment promotes SH-SY5Y cell apoptosis via c-Jun N-terminal kinase-mediated activation of mitochondria-dependent pathway.","volume":"276","author":"Lin","year":"2009","journal-title":"FEBS J"},{"issue":"5","key":"R35-11-20210126","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1152\/japplphysiol.91523.2008","article-title":"Effects of acute intermittent hypoxia on glucose metabolism in awake healthy volunteers.","volume":"106","author":"Louis","year":"2009","journal-title":"J Appl Physiol"},{"issue":"8","key":"R36-11-20210126","first-page":"599","article-title":"Morphine decreases early peritoneal innate immunity responses in Swiss-Webster and C57BL6J mice through the inhibition of mast cell TNF- release.","volume":"32","author":"Madera-Salcedo","year":"2010","journal-title":"J Neuroimmunol"},{"key":"R37-11-20210126","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1007\/BF00280883","article-title":"Homeostasis model assessment: insulin resistance and -cell function from fasting plasma glucose and insulin concentrations in man.","volume":"28","author":"Matthews","year":"1985","journal-title":"Diabetologia"},{"issue":"3","key":"R38-11-20210126","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1097\/00008506-199907000-00007","article-title":"Heart rate variability and plasma catecholamines in patients during opioid detoxification.","volume":"11","author":"McDonald","year":"1999","journal-title":"J Neurosurg Anesthesiol"},{"issue":"2","key":"R39-11-20210126","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1111\/j.1471-4159.2009.06156.x","article-title":"Inhibition of EGF-induced ERKMAP kinase-mediated astrocyte proliferation by mu opioids: integration of G protein and -arrestin 2-dependent pathways.","volume":"110","author":"Miyatake","year":"2009","journal-title":"J Neurochem"},{"issue":"1-2","key":"R40-11-20210126","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/0006-8993(94)91962-3","article-title":"Differential hemodynamic, metabolic and hormonal effects of morphine and morphine-6-glucuronide.","volume":"664","author":"Molina","year":"1994","journal-title":"Brain Res"},{"key":"R41-11-20210126","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1007\/BF03346942","article-title":"Impaired insulin response to glucose but not to arginine in heroin addicts.","volume":"9","author":"Passariello","year":"1986","journal-title":"J Endocrinol Invest"},{"issue":"7","key":"R42-11-20210126","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/0002-9149(94)90676-9","article-title":"Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women.","volume":"73","author":"Pouliot","year":"1994","journal-title":"Am J Cardiol"},{"key":"R43-11-20210126","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1136\/bmj.2.5866.582","article-title":"Oral glucose tolerance and hormonal response in heroin-dependent males.","volume":"2","author":"Reed","year":"1973","journal-title":"BMJ"},{"issue":"4","key":"R44-11-20210126","first-page":"217","article-title":"Does opioid therapy affect quality of care for diabetes mellitus Am J Manag C","volume":"15","author":"Rose","year":"2009","journal-title":"are"},{"key":"R45-11-20210126","doi-asserted-by":"crossref","first-page":"1562","DOI":"10.2337\/diabetes.47.10.1562","article-title":"Prolonged oxidative stress impairs insulin-induced GLUT4 translocation in 3T3L-1 adipocites.","volume":"47","author":"Rudidi","year":"1998","journal-title":"Diabetes"},{"key":"R46-11-20210126","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1126\/science.1160794","article-title":"A stress signaling pathway in adipose tissue regulates hepatic insulin resistance.","volume":"322","author":"Sabio","year":"2008","journal-title":"Science"},{"issue":"4","key":"R47-11-20210126","first-page":"492","article-title":"Utilization of on-site primary care services by HIV-seropositive and seronegative drug users in a methadone maintenance program.","volume":"108","author":"Selwyn","year":"1993","journal-title":"Public Health Rep"},{"issue":"8","key":"R48-11-20210126","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/S0006-3223(03)00290-7","article-title":"Safety of injectable opioid maintenance treatment for heroin dependence.","volume":"54","author":"Stoermera","year":"2003","journal-title":"Biol Psychiatry"},{"issue":"6","key":"R49-11-20210126","doi-asserted-by":"crossref","first-page":"3401","DOI":"10.1210\/jc.2004-0761","article-title":"Combination therapy with epidermal growth factor and gastrin induces neogenesis of human Islet -cells from pancreatic duct cells and an increase in functional -cell mass.","volume":"90","author":"Suarez-Pinzon","year":"2005","journal-title":"J Clin Endocrinol Metab"},{"issue":"1","key":"R50-11-20210126","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1042\/bj2450019","article-title":"Effect of cyclic AMP-dependent protein kinase on insulin receptor tyrosine kinase activity.","volume":"245","author":"Tanti","year":"1987","journal-title":"Biochem J"},{"key":"R51-11-20210126","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.2337\/diab.46.11.1733","article-title":"Relation between antioxidant enzyme gene expression and antioxidative defense status of insulin-producing cells.","volume":"46","author":"Tiedge","year":"1997","journal-title":"Diabetes"},{"issue":"11","key":"R52-11-20210126","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1016\/0026-0495(79)90146-X","article-title":"Insulin deficiency and insulin resistance interaction in diabetes: estimation of their relative contribution by feedback analysis from basal plasma insulin and glucose concentrations.","volume":"28","author":"Turner","year":"1979","journal-title":"Metabolism"},{"issue":"2","key":"R53-11-20210126","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/0167-4889(86)90024-8","article-title":"The significance of mu- and delta-receptors in rat pancreatic islets for the opioid-mediated insulin release.","volume":"888","author":"Verspohl","year":"1986","journal-title":"Biochim Biophys Acta"},{"issue":"3","key":"R54-11-20210126","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1042\/cs0740283","article-title":"Effects of heroin addiction on the response of glucose, C-peptide and insulin to a standard meal.","volume":"74","author":"Zandomeneghi","year":"1988","journal-title":"Clin Sci (Lond)"},{"issue":"3","key":"R55-11-20210126","first-page":"387","article-title":"Leptin, adiponectin, leptin to adiponectin ratio and insulin resistance in depressive women.","volume":"30","author":"Zeman","year":"2009","journal-title":"Neuro Endocrinol Lett"},{"key":"R56-11-20210126","first-page":"131","article-title":"Heroin abuse and nitric oxide, oxidation, peroxidation, lipoperoxidation.","volume":"13","author":"Zhou","year":"2000","journal-title":"Biomed Environ Sci"}],"container-title":["Journal of Addiction Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/ADM.0b013e31826bd76c","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,25]],"date-time":"2023-06-25T23:35:16Z","timestamp":1687736116000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01271255-201212000-00011"}},"subtitle":["Mechanisms and Consequences of Impaired Insulin Sensitivity in Hepatitis C Virus Seronegative Heroin Dependents"],"short-title":[],"issued":{"date-parts":[[2012,12]]},"references-count":55,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/adm.0b013e31826bd76c","relation":{},"ISSN":["1932-0620"],"issn-type":[{"value":"1932-0620","type":"print"}],"subject":[],"published":{"date-parts":[[2012,12]]}}}