{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T02:00:11Z","timestamp":1791856811519,"version":"4.3.4"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2010,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To identify signs of temporomandibular disorders and cervical pain in individuals with episodic and chronic (transformed) migraine (CM), relative to controls without headaches.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      In this prospective, controlled, double-blind study, we examined 93 individuals divided in 3 groups: episodic migraine EM, (n=31), CM chronic migraine (n=34), and controls without migraine (n=28). We recorded signs of temporomandibular disorders, and of pain in the neck, after the protocol of Helkimo (1974). We calculated the odds ratio (OR) and confidence intervals (CI) of symptoms as a function of headache status. Data from all groups were paired and compared using the \u03c7\n                      <jats:sup>2<\/jats:sup>\n                      test. The level of significance was 5% in 2-tailed tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Relative to controls, participants with EM and CM were significantly more likely to have tenderness in the masticatory muscles [controls=28%, migraine=54%, (OR=3.0, 95% CI=1.1-8.9), CM=73% (OR=6.9, 95% CI=2.3-21.2)], and in the temporomandibular joint [controls=25%, migraine=61%, (OR=4.7, 95% CI=1.5-14.5), CM=61% (OR=4.8, 95% CI=1.6-14.5)]. They were numerically (but nonsignificantly) more likely to have limited lateral jaw movements (CM=34%; EM=26%; NP=18%), joint sounds (CM=44%; EM=29%; NP=28%), and tenderness in neck muscles (CM=64%; EM=51%; NP=35%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In a tertiary care population, individuals with EM and CM are more likely to have tenderness at the temporomandibular joint and on the masticatory muscles, relative to controls. Studies are needed to investigate whether treatment of 1 disorder will improve the other.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/ajp.0b013e3181d10691","type":"journal-article","created":{"date-parts":[[2010,5,14]],"date-time":"2010-05-14T03:41:26Z","timestamp":1273808486000},"page":"418-421","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":45,"title":["Signs of Temporomandibular Disorders in Migraine Patients: A Prospective, Controlled Study"],"prefix":"10.1097","volume":"26","author":[{"given":"Juliana","family":"Stuginski-Barbosa","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique R.","family":"Macedo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo","family":"Eduardo Bigal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Geraldo","family":"Speciali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20251219","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1016\/0895-4356(91)90147-2","article-title":"Epidemiology of headache in a general population\u2014a prevalence study","volume":"44","author":"Rasmussen","year":"1991","journal-title":"J Clin Epidemiol"},{"key":"R2-9-20251219","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1212\/01.wnl.0000252808.97649.21","article-title":"Migraine prevalence, disease burden, and the need for preventive therapy","volume":"68","author":"Lipton","year":"2007","journal-title":"Neurology"},{"key":"R3-9-20251219","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1046\/j.1526-4610.1998.3807497.x","article-title":"Prevalence of frequent headache in a population sample","volume":"38","author":"Scher","year":"1998","journal-title":"Headache"},{"key":"R4-9-20251219","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1590\/S0004-282X1993000300002","article-title":"Prevalence of headache as an symptom in a urban area of Salvador, Bahia","volume":"51","author":"Bastos","year":"1993","journal-title":"Arq Neuropsiquiatr"},{"key":"R5-9-20251219","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1590\/S0004-282X2000000300007","article-title":"Migraine prevalence and impact in employees of the clinical hospital of the medical school of Ribeirao Preto\u2014USP","volume":"58","author":"Bigal","year":"2000","journal-title":"Arq Neuropsiquiatr"},{"key":"R6-9-20251219","doi-asserted-by":"crossref","first-page":"1334","DOI":"10.1111\/j.1526-4610.2006.00577.x","article-title":"Modifiable risk factors for migraine progression","volume":"46","author":"Bigal","year":"2006","journal-title":"Headache"},{"key":"R7-9-20251219","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1111\/j.1526-4610.2007.00970.x","article-title":"Risk factors for headache chronification","volume":"48","author":"Scher","year":"2008","journal-title":"Headache"},{"key":"R8-9-20251219","article-title":"Orofacial Pain. 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