{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T19:46:35Z","timestamp":1768679195625,"version":"3.49.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec>\n            <jats:title>Objective:<\/jats:title>\n            <jats:p>Botulinum toxin is a neurotoxin that has been widely used in chronic pain for the treatment of multiple conditions with a component of localized muscle spasm. Recent studies suggest that botulinum toxin is effective in the treatment of neuropathic pain syndromes such as postherpetic neuralgia or painful scars.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>We searched the PubMed and OvidSP databases. We also included cross-referencing bibliographies from primary and review articles.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Discussion:<\/jats:title>\n            <jats:p>In this descriptive review, we evaluate the usefulness, safety, and potential pathophysiological mechanism of botulinum toxin type A for treatment of painful disorders with neuropathic component such as postherpetic neuralgia, diabetic neuropathy, or trigeminal neuralgia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>On the basis of the analysis of the reports published in the literature, it would seem that fractioned peripheral subcutaneous and perineural injections of botulinum toxin type A may be useful for the treatment of various chronic pain conditions with neuropathic component.<\/jats:p>\n          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botulinum toxin type A into trigger zone of trigeminal neuralgia as a means to control pain.","volume":"109","author":"Ngeow","year":"2010","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"R27-13-20240226","doi-asserted-by":"crossref","first-page":"1476","DOI":"10.1111\/j.1526-4610.2008.01089.x","article-title":"Botulinum toxin type A in the treatment of occipital neuralgia: a pilot study.","volume":"48","author":"Taylor","year":"2008","journal-title":"Headache"},{"key":"R33-13-20240226","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00702-004-0265-1","article-title":"Botulinum toxin type A in experimental neuropathic pain.","volume":"112","author":"Bach-Rojecky","year":"2005","journal-title":"J Neural Transm"},{"key":"R34-13-20240226","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejphar.2010.01.020","article-title":"Botulinum toxin type A reduces pain supersensitivity in experimental diabetic neuropathy: bilateral effect after unilateral injection.","volume":"633","author":"Bach-Rojecky","year":"2010","journal-title":"Eur J Pharmacol"},{"key":"R36-13-20240226","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1016\/j.jbiomech.2007.11.016","article-title":"Botox produces functional weakness in non-injected muscles adjacent to the target muscle.","volume":"41","author":"Yaraskavitch","year":"2008","journal-title":"J Biomech"}],"container-title":["The Clinical Journal of Pain"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00002508-201311000-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T12:00:49Z","timestamp":1708948849000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00002508-201311000-00013"}},"subtitle":["A Descriptive 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