{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T02:11:15Z","timestamp":1785723075819,"version":"3.56.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":["Anesthesiology"],"published-print":{"date-parts":[[2011,3,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Previous studies have reported a greater frequency of sensitization to latex in the female population and a higher incidence of anaphylactic reactions to latex during cesarean section. In this study, the authors investigated the prevalence of latex sensitization in obstetric patients compared with nonpregnant subjects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two hundred ninety-four healthy pregnant women who were at term with a singleton fetus and scheduled for caesarean section (group A) were compared with 294 healthy nulliparous women with childbirth potential undergoing gynecologic surgery (group B). Before surgery, patients completed a questionnaire, and venous blood samples were collected to measure specific immunoglobulin E serum concentrations with a fluorescent enzyme immunoassay test. Skin-prick tests were performed if adverse reactions occurred during surgery. Latex allergy was diagnosed on the basis of immunoglobulin E results and\/or positive skin-prick tests.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The prevalence of latex sensitization was higher in group A than in group B (15\/294, 5.1% vs. 5\/294, 1.7%; P &lt; 0.05). A significant difference in specific immunoglobulin E serum concentration was noted between pregnant and nonpregnant patients who had a positive fluorescent enzyme immunoassay test (median serum concentration: 1.93 kilounits\/l; interquartile range = 2.28 vs. 0.78 kilounits\/l; interquartile range = 1.07; P less than 0.05). Two patients in group A experienced an anaphylactic reaction to latex. Statistical analysis disclosed no association between latex sensitization and accepted risk factor for latex allergy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The authors report a higher prevalence of latex sensitization in the obstetric population than in nonpregnant subjects undergoing gynecologic surgery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/aln.0b013e318206ff50","type":"journal-article","created":{"date-parts":[[2011,1,21]],"date-time":"2011-01-21T03:20:12Z","timestamp":1295580012000},"page":"565-569","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":37,"title":["Latex Sensitization"],"prefix":"10.1097","volume":"114","author":[{"given":"Gaetano","family":"Draisci","sequence":"first","affiliation":[{"name":"Staff Anesthesiologist, Department of Anesthesiology and Intensive Care."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno A.","family":"Zanfini","sequence":"additional","affiliation":[{"name":"Staff Anesthesiologist, Department of Anesthesiology and Intensive Care."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eleonora","family":"Nucera","sequence":"additional","affiliation":[{"name":"Staff Allergologist, Department of Allergology."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Catarci","sequence":"additional","affiliation":[{"name":"Staff Anesthesiologist, Department of Anesthesiology and Intensive Care."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raffaella","family":"Sangregorio","sequence":"additional","affiliation":[{"name":"Resident in Anesthesiology, Department of Anesthesiology and Intensive Care, Catholic University of Sacred Heart, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Domenico","family":"Schiavino","sequence":"additional","affiliation":[{"name":"Staff Allergologist, Department of Allergology."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alice","family":"Mannocci","sequence":"additional","affiliation":[{"name":"Staff Biostatistic, Unit of Hygiene, Department of Public Health and Infectious Diseases, Sapienza University of Roma, Rome, Italy."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giampiero","family":"Patriarca","sequence":"additional","affiliation":[{"name":"Staff Allergologist, Department of Allergology."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-21-20250925"},{"key":"R2-21-20250925"},{"key":"R3-21-20250925"},{"key":"R4-21-20250925"},{"key":"R5-21-20250925"},{"key":"R6-21-20250925"},{"key":"R7-21-20250925"},{"key":"R8-21-20250925"},{"key":"R9-21-20250925"},{"key":"R10-21-20250925"},{"key":"R11-21-20250925"},{"key":"R12-21-20250925"},{"key":"R13-21-20250925"},{"key":"R14-21-20250925"},{"key":"R15-21-20250925"},{"key":"R16-21-20250925"},{"key":"R17-21-20250925"},{"key":"R18-21-20250925"},{"key":"R19-21-20250925"},{"key":"R20-21-20250925"},{"key":"R21-21-20250925"},{"key":"R22-21-20250925"},{"key":"R23-21-20250925"},{"key":"R24-21-20250925"},{"key":"R25-21-20250925"},{"key":"R26-21-20250925"},{"key":"R27-21-20250925"},{"key":"R28-21-20250925"},{"key":"R29-21-20250925"},{"key":"R30-21-20250925"}],"container-title":["Anesthesiology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/pubs.asahq.org\/anesthesiology\/article-pdf\/114\/3\/565\/253040\/0000542-201103000-00021.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/journals.lww.com\/00000542-201103000-00017","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T17:04:05Z","timestamp":1758819845000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00000542-201103000-00017"}},"subtitle":["A Special Risk for the Obstetric Population?"],"short-title":[],"issued":{"date-parts":[[2011,3,1]]},"references-count":30,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/aln.0b013e318206ff50","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.10875956.11831055","asserted-by":"object"}]},"ISSN":["0003-3022"],"issn-type":[{"value":"0003-3022","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3,1]]}}}