{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:07:03Z","timestamp":1788923223599,"version":"build-2803163510"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1097\/ana.0b013e31822ff779","type":"journal-article","created":{"date-parts":[[2011,10,4]],"date-time":"2011-10-04T16:25:40Z","timestamp":1317745540000},"page":"63-70","source":"Crossref","is-referenced-by-count":35,"title":["Long-term Intrathecal Drug Administration for Chronic Nonmalignant Pain"],"prefix":"10.1097","volume":"24","author":[{"given":"Rui V.","family":"Duarte","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon H.","family":"Raphael","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth","family":"Sparkes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jane L.","family":"Southall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen","family":"LeMarchand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert L.","family":"Ashford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20210126","first-page":"249","article-title":"Pain terms: a list with definitions and notes on usage. Recommended by the IASP Subcommittee on Taxonomy.","volume":"6","year":"1979","journal-title":"Pain"},{"key":"R3-11-20210126","first-page":"516","article-title":"Continuous low-dose intrathecal morphine administration in the treatment of chronic pain of malignant origin.","volume":"56","author":"Onofrio","year":"1981","journal-title":"Mayo Clin Proc"},{"key":"R4-11-20210126","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1046\/j.1525-1403.1999.00077.x","article-title":"Cost effectiveness of intrathecal therapy for pain.","volume":"2","author":"Mueller-Schwefe","year":"1999","journal-title":"Neuromodulation"},{"key":"R5-11-20210126","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1227\/00006123-199111000-00025","article-title":"Spinal cord compression complicating subarachnoid infusion of morphine: case report and laboratory experience.","volume":"29","author":"North","year":"1991","journal-title":"Neurosurgery"},{"key":"R6-11-20210126","doi-asserted-by":"crossref","first-page":"2336","DOI":"10.1001\/jama.1983.03340170062030","article-title":"Relief of continuous chronic pain by intraspinal narcotics infusion via an implanted reservoir.","volume":"250","author":"Coombs","year":"1983","journal-title":"JAMA"},{"key":"R7-11-20210126","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/S0149-2918(97)80077-X","article-title":"Cost-effectiveness of long-term intrathecal morphine therapy for pain associated with failed back surgery syndrome.","volume":"19","author":"de Lissovoy","year":"1997","journal-title":"Clin Ther"},{"key":"R9-11-20210126","doi-asserted-by":"crossref","first-page":"E175","DOI":"10.36076\/ppj.2010\/13\/E175","article-title":"Consensus guidelines for the selection and implantation of patients with noncancer pain for intrathecal drug delivery.","volume":"13","author":"Deer","year":"2010","journal-title":"Pain Physician"},{"key":"R10-11-20210126","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/S0090-3019(01)00353-6","article-title":"Continuous intrathecal morphine treatment for chronic pain of nonmalignant etiology: long-term benefits and efficacy.","volume":"55","author":"Kumar","year":"2001","journal-title":"Surg Neurol"},{"key":"R11-11-20210126","first-page":"CD006605","article-title":"Long-term opioid management for chronic noncancer pain.","volume":"1","author":"Noble","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"R13-11-20210126","first-page":"345","article-title":"Systematic review of intrathecal infusion systems for long-term management of chronic non-cancer pain.","volume":"12","author":"Patel","year":"2009","journal-title":"Pain Physician"},{"key":"R14-11-20210126","doi-asserted-by":"crossref","first-page":"1010","DOI":"10.1111\/j.1526-4637.2010.00876.x","article-title":"Intrathecal opioid therapy for chronic nonmalignant pain: a retrospective cohort study with 3-year follow-up.","volume":"11","author":"Atli","year":"2010","journal-title":"Pain Med"},{"key":"R15-11-20210126","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/0885-3924(95)00087-F","article-title":"Long-term intraspinal infusions of opioids in the treatment of neuropathic pain.","volume":"10","author":"Hassenbusch","year":"1995","journal-title":"J Pain Symptom Manage"},{"key":"R16-11-20210126","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1097\/01.ajp.0000210955.93878.44","article-title":"Programmable intrathecal opioid delivery systems for chronic noncancer pain: a systematic review of effectiveness and complications.","volume":"23","author":"Turner","year":"2007","journal-title":"Clin J Pain"},{"key":"R17-11-20210126","first-page":"117","article-title":"Long-term spinal analgesic delivery: a review of the preclinical and clinical literature.","volume":"25","author":"Wallace","year":"2000","journal-title":"Reg Anesth Pain Med"},{"key":"R18-11-20210126","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1046\/j.1525-1403.1999.00055.x","article-title":"Intrathecal therapy for cancer and nonmalignant pain: patient selection and patient management.","volume":"2","author":"Deer","year":"1999","journal-title":"Neuromodulation"},{"key":"R19-11-20210126","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-2474-3-17","article-title":"Long-term experience with implanted intrathecal drug administration systems for failed back syndrome and chronic mechanical low back pain.","volume":"3","author":"Raphael","year":"2002","journal-title":"BMC Musculoskelet Disord"},{"key":"R20-11-20210126","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/j.ejpain.2009.07.006","article-title":"Severe chronic pain is associated with increased 10 year mortality. A cohort record linkage study.","volume":"14","author":"Torrance","year":"2010","journal-title":"Eur J Pain"},{"key":"R21-11-20210126","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1111\/j.1526-4637.2010.00889.x","article-title":"Medical practice perspective: identification and mitigation of risk factors for mortality associated with intrathecal opioids for non-cancer pain.","volume":"11","author":"Coffey","year":"2010","journal-title":"Pain Med"},{"key":"R22-11-20210126","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.jpain.2010.02.019","article-title":"Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-base.","volume":"11","author":"Chapman","year":"2010","journal-title":"J Pain"},{"key":"R23-11-20210126","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0304-3959(93)90184-Q","article-title":"Vivid memory for everyday pains.","volume":"55","author":"Morley","year":"1993","journal-title":"Pain"},{"key":"R24-11-20210126","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S1058-9139(05)80087-7","article-title":"The accuracy of memory for pain: not so bad most of the time.","volume":"2","author":"Salovey","year":"1993","journal-title":"APS J"},{"key":"R26-11-20210126","first-page":"129","article-title":"Pain assessment: global use of the Brief Pain Inventory.","volume":"23","author":"Cleeland","year":"1994","journal-title":"Ann Acad Med Singapore"},{"key":"R27-11-20210126","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.pain.2004.09.012","article-title":"Core outcome measures for chronic pain clinical trials: IMMPACT recommendations.","volume":"113","author":"Dworkin","year":"2005","journal-title":"Pain"},{"key":"R28-11-20210126","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/S0304-3959(01)00349-9","article-title":"Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale.","volume":"94","author":"Farrar","year":"2001","journal-title":"Pain"},{"key":"R29-11-20210126","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jpain.2007.09.005","article-title":"Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations.","volume":"9","author":"Dworkin","year":"2008","journal-title":"J Pain"},{"key":"R30-11-20210126","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.pain.2010.05.011","article-title":"Evidence in chronic painestablishing best practice in the reporting of systematic reviews.","volume":"150","author":"Moore","year":"2010","journal-title":"Pain"},{"key":"R31-11-20210126","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1525-1403.2008.00147.x","article-title":"Management of intrathecal catheter-tip inflammatory masses: an updated 2007 consensus statement from an expert panel.","volume":"11","author":"Deer","year":"2008","journal-title":"Neuromodulation"},{"key":"R32-11-20210126","doi-asserted-by":"crossref","first-page":"458","DOI":"10.3171\/jns.1996.85.3.0458","article-title":"Long-term effects of continuous intrathecal opioid treatment in chronic pain of nonmalignant etiology.","volume":"85","author":"Winkelmuller","year":"1996","journal-title":"J Neurosurg"},{"key":"R33-11-20210126","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0885-3924(95)00099-2","article-title":"Intraspinal morphine for chronic pain: a retrospective, multicenter study.","volume":"11","author":"Paice","year":"1996","journal-title":"J Pain Symptom Manage"},{"key":"R34-11-20210126","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.pain.2004.01.003","article-title":"Intrathecal opioid treatment for chronic non-malignant pain: a 3-year prospective study.","volume":"109","author":"Thimineur","year":"2004","journal-title":"Pain"},{"key":"R35-11-20210126","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/BF03011037","article-title":"Side effects of intrathecal and epidural opioids.","volume":"42","author":"Chaney","year":"1995","journal-title":"Can J Anaesth"},{"key":"R36-11-20210126","doi-asserted-by":"crossref","first-page":"357","DOI":"10.36076\/ppj.2007\/10\/357","article-title":"Drug-related side effects of long-term intrathecal morphine therapy.","volume":"10","author":"Ruan","year":"2007","journal-title":"Pain Physician"},{"key":"R37-11-20210126","first-page":"5","article-title":"Sexual dysfunction and other side effects of intraspinal opiate use in the management of chronic non-cancer pain.","volume":"8","author":"Doleys","year":"1998","journal-title":"Am J Pain Manage"},{"key":"R38-11-20210126","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/AJP.0b013e3181850df6","article-title":"The impact of opioids on the endocrine system.","volume":"25","author":"Katz","year":"2009","journal-title":"Clin J Pain"},{"key":"R39-11-20210126","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1210\/jcem.85.6.6615","article-title":"Endocrine consequences of long-term intrathecal administration of opioids.","volume":"85","author":"Abs","year":"2000","journal-title":"J Clin Endocrinol Metab"},{"key":"R40-11-20210126","first-page":"109","article-title":"Intrathecal inflammatory masses: is the yearly opioid dose increase an early indicator Neuromodulation.","volume":"13","author":"Duarte","year":"2010","journal-title":""},{"key":"R41-11-20210126","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0304-3959(93)90191-Q","article-title":"Long-term intrathecal infusion of morphine and morphinebupivacaine mixtures in the treatment of cancer pain: a retrospective analysis of 51 cases.","volume":"55","author":"Van Dongen","year":"1993","journal-title":"Pain"},{"key":"R42-11-20210126","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1097\/00000542-199402000-00008","article-title":"Long-term intrathecal morphine and bupivacaine in patients with refractory cancer pain. Results from a morphine: bupivacaine dose regimen of 0.5:4.75mgmL.","volume":"80","author":"Sjoberg","year":"1994","journal-title":"Anesthesiology"},{"key":"R43-11-20210126","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1097\/00006123-199805000-00142","article-title":"Spinal cord compression by catheter granulomas in high-dose intrathecal morphine therapy: case report.","volume":"42","author":"Cabbell","year":"1998","journal-title":"Neurosurgery"},{"key":"R44-11-20210126","doi-asserted-by":"crossref","first-page":"S12","DOI":"10.1016\/S0885-3924(00)00204-9","article-title":"Evidence-based review of the literature on intrathecal delivery of pain medication.","volume":"20","author":"Bennett","year":"2000","journal-title":"J Pain Symptom Manage"},{"key":"R45-11-20210126","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1097\/00000542-200603000-00025","article-title":"Opioid-induced hyperalgesia: a qualitative systematic review.","volume":"104","author":"Angst","year":"2006","journal-title":"Anesthesiology"},{"key":"R46-11-20210126","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1097\/AJP.0b013e31816b2f43","article-title":"Opioid-induced hyperalgesia in humans: molecular mechanisms and clinical considerations.","volume":"24","author":"Chu","year":"2008","journal-title":"Clin J Pain"},{"key":"R47-11-20210126","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/S0090-3019(96)00466-1","article-title":"Intrathecal granuloma after implantation of a morphine pump: case report and review of the literature.","volume":"48","author":"Bejjani","year":"1997","journal-title":"Surg Neurol"}],"container-title":["Journal of Neurosurgical Anesthesiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00008506-201201000-00011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T20:30:55Z","timestamp":1786048255000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00008506-201201000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/ana.0b013e31822ff779","relation":{},"ISSN":["0898-4921"],"issn-type":[{"value":"0898-4921","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}