{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:21:02Z","timestamp":1786119662828,"version":"build-2736575974"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,3]]},"DOI":"10.1097\/aog.0b013e31820b3c61","type":"journal-article","created":{"date-parts":[[2011,2,23]],"date-time":"2011-02-23T03:18:19Z","timestamp":1298431099000},"page":"573-582","source":"Crossref","is-referenced-by-count":51,"title":["Development of a Multiple Marker Test for Ectopic Pregnancy"],"prefix":"10.1097","volume":"117","author":[{"given":"Mary E.","family":"Rausch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary D.","family":"Sammel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Takacs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karine","family":"Chung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alka","family":"Shaunik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kurt T.","family":"Barnhart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-9-20210126","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1056\/NEJMcp0810384","article-title":"Clinical practice. Ectopic pregnancy.","volume":"361","author":"Barnhart","year":"2009","journal-title":"N Engl J Med"},{"key":"R2-9-20210126","doi-asserted-by":"crossref","first-page":"2824","DOI":"10.1093\/humrep\/dem283","article-title":"The diagnostic effectiveness of an initial transvaginal scan in detecting ectopic pregnancy.","volume":"22","author":"Kirk","year":"2007","journal-title":"Hum Reprod"},{"key":"R3-9-20210126","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1111\/j.1471-0528.2003.02253.x","article-title":"Improved fertility following conservative surgical treatment of ectopic pregnancy.","volume":"110","author":"Bangsgaard","year":"2003","journal-title":"BJOG"},{"key":"R4-9-20210126","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.fertnstert.2006.11.005","article-title":"Care pathways for ectopic pregnancy: a population-based cost-effectiveness analysis.","volume":"87","author":"Seror","year":"2007","journal-title":"Fertil Steril"},{"key":"R5-9-20210126","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1530\/REP-09-0060","article-title":"Serum biomarkers of tubal ectopic pregnancy: current candidates and future possibilities.","volume":"138","author":"Cartwright","year":"2009","journal-title":"Reproduction"},{"key":"R6-9-20210126","article-title":"Methods in observational epidemiology.","author":"Kelsely","year":"1996"},{"key":"R7-9-20210126","doi-asserted-by":"crossref","first-page":"2137","DOI":"10.1016\/j.fertnstert.2008.12.121","article-title":"Proteomic analysis of serum yields six candidate proteins that are differentially regulated in a subset of women with endometriosis.","volume":"93","author":"Seeber","year":"2010","journal-title":"Fertil Steril"},{"key":"R8-9-20210126","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1016\/j.fertnstert.2007.05.014","article-title":"Panel of markers can accurately predict endometriosis in a subset of patients.","volume":"89","author":"Seeber","year":"2008","journal-title":"Fertil Steril"},{"key":"R9-9-20210126","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/j.1600-0897.2007.00512.x","article-title":"Progesterone during pregnancy: endocrine-immune cross talk in mammalian species and the role of stress.","volume":"58","author":"Arck","year":"2007","journal-title":"Am J Reprod Immunol"},{"key":"R10-9-20210126","doi-asserted-by":"crossref","first-page":"3220","DOI":"10.1093\/humrep\/13.11.3220","article-title":"The accuracy of single serum progesterone measurement in the diagnosis of ectopic pregnancy: a meta-analysis.","volume":"13","author":"Mol","year":"1998","journal-title":"Hum Reprod"},{"key":"R11-9-20210126","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1210\/jcem.82.5.3934","article-title":"Inhibin A and activin A in the first trimester of human pregnancy.","volume":"82","author":"Birdsall","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"R12-9-20210126","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1093\/humrep\/12.5.1089","article-title":"Source of circulating levels of inhibin A, pro alpha C-containing inhibins and activin A in early pregnancy.","volume":"12","author":"Muttukrishna","year":"1997","journal-title":"Hum Reprod"},{"key":"R13-9-20210126","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1530\/eje.1.01928","article-title":"The secretion and effect of inhibin A, activin A and follistatin on first-trimester trophoblasts in vitro.","volume":"152","author":"Bearfield","year":"2005","journal-title":"Eur J Endocrinol"},{"key":"R14-9-20210126","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/humupd\/dmh057","article-title":"Inhibins in female and male reproductive physiology: role in gametogenesis, conception, implantation and early pregnancy.","volume":"11","author":"Luisi","year":"2005","journal-title":"Hum Reprod Update"},{"key":"R15-9-20210126","doi-asserted-by":"crossref","first-page":"3530","DOI":"10.1093\/humrep\/13.12.3530","article-title":"A longitudinal study of maternal serum inhibin-A, inhibin-B, activin-A, activin-AB, pro-alphaC and follistatin during pregnancy.","volume":"13","author":"Fowler","year":"1998","journal-title":"Hum Reprod"},{"key":"R16-9-20210126","doi-asserted-by":"crossref","first-page":"2451","DOI":"10.1093\/humrep\/dep066","article-title":"The use of serum inhibin A and activin A levels in predicting the outcome of \u2018pregnancies of unknown location.\u2019","volume":"24","author":"Kirk","year":"2009","journal-title":"Hum Reprod"},{"key":"R17-9-20210126","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/S1472-6483(10)60406-3","article-title":"Inhibin A: marker for diagnosis of ectopic and early abnormal pregnancies.","volume":"17","author":"Segal","year":"2008","journal-title":"Reprod Biomed Online"},{"key":"R18-9-20210126","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1093\/humrep\/13.4.1057","article-title":"A longitudinal study of maternal serum vascular endothelial growth factor in early pregnancy.","volume":"13","author":"Evans","year":"1998","journal-title":"Hum Reprod"},{"key":"R19-9-20210126","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1016\/j.fertnstert.2003.12.052","article-title":"Increased messenger RNA expression of vascular endothelial growth factor and its receptors in the implantation site of the human oviduct with ectopic gestation.","volume":"82","author":"Lam","year":"2004","journal-title":"Fertil Steril"},{"key":"R20-9-20210126","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1093\/humrep\/17.2.490","article-title":"Serum vascular endothelial growth factor as a possible marker for early ectopic pregnancy.","volume":"17","author":"Felemban","year":"2002","journal-title":"Hum Reprod"},{"key":"R21-9-20210126","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/S0015-0282(99)00417-3","article-title":"Levels of vascular endothelial growth factor are elevated in patients with ectopic pregnancy: is this a novel marker?","volume":"72","author":"Daniel","year":"1999","journal-title":"Fertil Steril"},{"key":"R22-9-20210126","doi-asserted-by":"crossref","first-page":"1106","DOI":"10.1016\/j.fertnstert.2003.08.049","article-title":"Novel placental and nonplacental serum markers in ectopic versus normal intrauterine pregnancy.","volume":"81","author":"Mueller","year":"2004","journal-title":"Fertil Steril"},{"key":"R23-9-20210126","first-page":"571","article-title":"Localization and regulation of the activin-A dimer in human placental cells.","volume":"75","author":"Rabinovici","year":"1992","journal-title":"J Clin Endocrinol Metab"},{"key":"R24-9-20210126","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1053\/plac.2002.0787","article-title":"The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour.","volume":"23","author":"Schneider-Kolsky","year":"2002","journal-title":"Placenta"},{"key":"R25-9-20210126","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1210\/endo.133.1.8319577","article-title":"Acute stimulation of human chorionic gonadotropin secretion by recombinant human activin-A in first trimester human trophoblast.","volume":"133","author":"Steele","year":"1993","journal-title":"Endocrinology"},{"key":"R26-9-20210126","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1093\/humrep\/14.3.827","article-title":"Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study.","volume":"14","author":"O'Connor","year":"1999","journal-title":"Hum Reprod"},{"key":"R27-9-20210126","doi-asserted-by":"crossref","first-page":"1748","DOI":"10.1210\/jc.2006-2188","article-title":"Single serum activin a testing to predict ectopic pregnancy.","volume":"92","author":"Florio","year":"2007","journal-title":"J Clin Endocrinol Metab"},{"key":"R28-9-20210126","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0028-2243(91)90074-U","article-title":"Serum levels of steroid and placental protein hormones in ectopic pregnancy.","volume":"39","author":"Mantzavinos","year":"1991","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R29-9-20210126","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/S0301-2115(01)00470-5","article-title":"Accuracy of single measurements of pregnancy-associated plasma protein-A, human chorionic gonadotropin and progesterone in the diagnosis of early pregnancy failure.","volume":"100","author":"Dumps","year":"2002","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R30-9-20210126","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1196\/annals.1318.046","article-title":"A serum proteomics approach to the diagnosis of ectopic pregnancy.","volume":"1022","author":"Gerton","year":"2004","journal-title":"Ann N Y Acad Sci"},{"key":"R31-9-20210126","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/S0015-0282(02)04853-7","article-title":"Serum concentrations of interleukin-2R (IL-2R), IL-6, IL-8, and tumor necrosis factor alpha in patients with ectopic pregnancy.","volume":"79","author":"Soriano","year":"2003","journal-title":"Fertil Steril"},{"key":"R32-9-20210126","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1016\/j.fertnstert.2007.10.063","article-title":"Early serum interleukin-8 evaluation may prove useful in localizing abnormally implanted human gestations after in vitro fertilization.","volume":"90","author":"Morelli","year":"2008","journal-title":"Fertil Steril"},{"key":"R33-9-20210126","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1053\/ajem.2000.7327","article-title":"The utility of maternal creatine kinase in the evaluation of ectopic pregnancy.","volume":"18","author":"Birkhahn","year":"2000","journal-title":"Am J Emerg Med"},{"key":"R34-9-20210126","doi-asserted-by":"crossref","first-page":"3348","DOI":"10.1093\/humrep\/dei227","article-title":"Do levels of serum cancer antigen 125 and creatine kinase predict the outcome in pregnancies of unknown location?","volume":"20","author":"Condous","year":"2005","journal-title":"Hum Reprod"},{"key":"R35-9-20210126","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.ajog.2005.06.047","article-title":"Creatine phosphokinase in ectopic pregnancy revisited: significant diagnostic value of its MB and MM isoenzyme fractions.","volume":"194","author":"Katsikis","year":"2006","journal-title":"Am J Obstet Gynecol"},{"key":"R36-9-20210126","first-page":"300","article-title":"Serum creatine kinase is not a reliable indicator of ectopic pregnancy.","volume":"46","author":"Kurzel","year":"2001","journal-title":"Int J Fertil Womens Med"},{"key":"R37-9-20210126","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.ijgo.2007.03.052","article-title":"Serum creatine kinase as a predictor of tubal ectopic pregnancy.","volume":"98","author":"Soundravally","year":"2007","journal-title":"Int J Gynaecol Obstet"},{"key":"R38-9-20210126","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1089\/15246090050073620","article-title":"Early diagnosis of ectopic pregnancy: can we do it accurately using a biochemical profile?","volume":"9","author":"Spitzer","year":"2000","journal-title":"J Womens Health Gend Based Med"}],"container-title":["Obstetrics & Gynecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/AOG.0b013e31820b3c61","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:52:07Z","timestamp":1786042327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006250-201103000-00009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,3]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/aog.0b013e31820b3c61","relation":{},"ISSN":["0029-7844"],"issn-type":[{"value":"0029-7844","type":"print"}],"subject":[],"published":{"date-parts":[[2011,3]]}}}