{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T07:46:50Z","timestamp":1790840810702,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,11,1]],"date-time":"2020-11-01T00:00:00Z","timestamp":1604188800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,27]],"date-time":"2023-12-27T00:00:00Z","timestamp":1703635200000},"content-version":"vor","delay-in-days":1151,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Asia-Pacific Journal of Ophthalmology"],"published-print":{"date-parts":[[2020,11]]},"DOI":"10.1097\/apo.0000000000000336","type":"journal-article","created":{"date-parts":[[2021,1,19]],"date-time":"2021-01-19T14:18:51Z","timestamp":1611065931000},"page":"565-570","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Bowman Layer Transplantation\u2014A Review"],"prefix":"10.1016","volume":"9","author":[{"given":"Jack S.","family":"Parker","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip W.","family":"Dockery","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerrit R.J.","family":"Melles","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1097\/APO.0000000000000336_bib1","doi-asserted-by":"crossref","first-page":"433","DOI":"10.2147\/OPTH.S141127","article-title":"Bowman's layer transplantation: evidence to date","volume":"12","author":"Sharma","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib2","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.joco.2017.11.002","article-title":"Updates on managements for keratoconus","volume":"30","author":"Mohammadpour","year":"2017","journal-title":"J Curr Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib3","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.survophthal.2015.02.004","article-title":"Treatment options for advanced keratoconus: a review","volume":"60","author":"Parker","year":"2015","journal-title":"Surv Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib4","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/ICU.0000000000000570","article-title":"Update on Bowman layer transplantation","volume":"30","author":"Tong","year":"2019","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib5","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","article-title":"Keratoconus","volume":"42","author":"Rabinowitz","year":"1998","journal-title":"Surv Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib6","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.exer.2005.09.021","article-title":"Stromal haze, myofibroblasts, and surface irregularity after PRK","volume":"82","author":"Netto","year":"2006","journal-title":"Exp Eye Res"},{"key":"10.1097\/APO.0000000000000336_bib7","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jtos.2015.08.006","article-title":"Salzmann's nodular degeneration","volume":"14","author":"Maharana","year":"2016","journal-title":"Ocul Surf"},{"key":"10.1097\/APO.0000000000000336_bib8","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.jcrs.2010.03.032","article-title":"Isolated Bowman layer transplantation to manage persistent subepithelial haze after excimer laser surface ablation","volume":"36","author":"Lie","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"10.1097\/APO.0000000000000336_bib9","doi-asserted-by":"crossref","first-page":"6143","DOI":"10.1167\/iovs.13-12535","article-title":"Age-related thinning of Bowman's layer in the human cornea in vivo","volume":"54","author":"Germundsson","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1097\/APO.0000000000000336_bib10","doi-asserted-by":"crossref","first-page":"24959","DOI":"10.1016\/S0021-9258(17)31483-7","article-title":"Type V collagen and Bowman's membrane. Quantitation of mRNA in corneal epithelium and stroma","volume":"269","author":"Gordon","year":"1994","journal-title":"J Biol Chem"},{"key":"10.1097\/APO.0000000000000336_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000265406","article-title":"Distribution of types I, II, III, IV and V collagen in normal and keratoconus corneas","volume":"18","author":"Nakayasu","year":"1986","journal-title":"Ophthalmic Res"},{"key":"10.1097\/APO.0000000000000336_bib12","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/0002-9394(60)90354-8","article-title":"The fine structure of Bowman's layer and the basement membrane of the corneal epithelium","volume":"50","author":"Holmberg","year":"1960","journal-title":"Am J Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib13","first-page":"1","article-title":"On the structural origin of refractive instability and corneal haze after excimer laser keratectomy for myopia","volume":"237","author":"Muller-Pedersen","year":"2003","journal-title":"Acta Ophthalmol Scand Suppl"},{"key":"10.1097\/APO.0000000000000336_bib14","doi-asserted-by":"crossref","first-page":"4192","DOI":"10.1167\/iovs.09-3781","article-title":"The role of Bowman's layer in corneal regeneration after phototherapeutic keratectomy: a prospective study using in vivo confocal microscopy","volume":"50","author":"Lagali","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"10.1097\/APO.0000000000000336_bib15","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1097\/PAT.0b013e3283511b42","article-title":"An in depth analysis of histopathological characteristics found in keratoconus","volume":"44","author":"Sykakis","year":"2012","journal-title":"Pathology"},{"key":"10.1097\/APO.0000000000000336_bib16","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/S0014-4835(88)80031-9","article-title":"Comparative studies of collagens in normal and keratoconus corneas","volume":"46","author":"Zimmermann","year":"1988","journal-title":"Exp Eye Res"},{"key":"10.1097\/APO.0000000000000336_bib17","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.3928\/1081597X-20080101-16","article-title":"Biomechanical and wound healing characteristics of corneas after excimer laser keratorefractive surgery: is there a difference between advanced surface ablation and sub-Bowman's keratomileusis?","volume":"24","author":"Dawson","year":"2008","journal-title":"J Refract Surg"},{"key":"10.1097\/APO.0000000000000336_bib18","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1097\/ICO.0000000000000905","article-title":"Donor tissue preparation for Bowman layer transplantation","volume":"35","author":"Groeneveld-van Beek","year":"2016","journal-title":"Cornea"},{"key":"10.1097\/APO.0000000000000336_bib19","doi-asserted-by":"crossref","first-page":"675","DOI":"10.5301\/ejo.5000990","article-title":"Technical feasibility of isolated Bowman layer graft preparation by femtosecond laser: a pilot study","volume":"27","author":"Parker","year":"2017","journal-title":"Eur J Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib20","doi-asserted-by":"crossref","first-page":"e8","DOI":"10.1097\/ICO.0000000000001142","article-title":"Keratoconus and Bowman layer transplantation","volume":"36","author":"Galvis","year":"2017","journal-title":"Cornea"},{"key":"10.1097\/APO.0000000000000336_bib21","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1001\/jamaophthalmol.2013.5841","article-title":"Midstromal isolated Bowman layer graft for reduction of advanced keratoconus: a technique to postpone penetrating or deep anterior lamellar keratoplasty","volume":"132","author":"van Dijk","year":"2014","journal-title":"JAMA Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib22","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.ophtha.2014.12.005","article-title":"Bowman layer transplantation to reduce and stabilize progressive, advanced keratoconus","volume":"122","author":"van Dijk","year":"2015","journal-title":"Ophthalmology"},{"key":"10.1097\/APO.0000000000000336_bib23","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1097\/ICO.0000000000000860","article-title":"Corneal densitometry and higher order aberrations after Bowman layer transplantation: 1-year results","volume":"35","author":"Luceri","year":"2016","journal-title":"Cornea"},{"key":"10.1097\/APO.0000000000000336_bib24","doi-asserted-by":"crossref","first-page":"776","DOI":"10.1055\/s-0043-111085","article-title":"Transplantation der Bowman-lamelle bei progressivem keratokonus \u2013 was bringt\u02bcs? [Bowman layer transplantation in progressive keratoconus - what is it good for?]","volume":"234","author":"Blasberg","year":"2017","journal-title":"Klin Monbl Augenheilkd"},{"key":"10.1097\/APO.0000000000000336_bib25","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/j.jcrs.2018.10.034","article-title":"Bowman layer transplantation using a femtosecond laser","volume":"45","author":"Garc\u00eda de Oteyza","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"10.1097\/APO.0000000000000336_bib26","doi-asserted-by":"crossref","first-page":"e1031","DOI":"10.1111\/aos.14104","article-title":"Use of intraoperative anterior segment optical coherence tomography for Bowman layer transplantation","volume":"97","author":"Tong","year":"2019","journal-title":"Acta Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib27","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1186\/s40662-018-0117-y","article-title":"Bowman layer transplantation in the treatment of keratoconus","volume":"5","author":"Dragnea","year":"2018","journal-title":"Eye Vis (Lond)"},{"key":"10.1097\/APO.0000000000000336_bib28","doi-asserted-by":"crossref","first-page":"e901","DOI":"10.1111\/aos.13745","article-title":"Validity of Bowman layer transplantation for keratoconus: visual performance at 5-7 years","volume":"96","author":"Zygoura","year":"2018","journal-title":"Acta Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib29","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1007\/s00417-018-3927-7","article-title":"Bowman layer transplantation: 5-year results","volume":"256","author":"van Dijk","year":"2018","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib30","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s40662-018-0121-2","article-title":"Manual mid-stromal dissection as a low risk procedure to stabilize mild to moderate progressive keratoconus","volume":"5","author":"Birbal","year":"2018","journal-title":"Eye Vis (Lond)"},{"key":"10.1097\/APO.0000000000000336_bib31","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/ICU.0000000000000665","article-title":"Potential benefits of modified corneal tissue grafts for keratoconus: Bowman layer \u2019inlay\u2019 and \u2019onlay\u2019 transplantation, and allogenic tissue ring segments","volume":"31","author":"Dapena","year":"2020","journal-title":"Curr Opin Ophthalmol"},{"key":"10.1097\/APO.0000000000000336_bib32","doi-asserted-by":"crossref","unstructured":"Parker JS, Dockery PW, Parker JS, Dapena I, van Dijk K, Melles GRJ. Bowman layer onlay graft for reducing fluctuation in visual acuity after previous radial keratotomy [published online ahead of print, 2020 May 4]. Cornea 2020; 10.1097\/ICO.0000000000002346.","DOI":"10.1097\/ICO.0000000000002346"},{"key":"10.1097\/APO.0000000000000336_bib33","doi-asserted-by":"crossref","unstructured":"Dapena I, Musayeva A, Dragnea DC, et al. Bowman layer onlay transplantation to manage herpes corneal scar [published online ahead of print, 2020 Feb 17]. Cornea 2020; 10.1097\/ICO.0000000000002292.","DOI":"10.1097\/ICO.0000000000002292"},{"key":"10.1097\/APO.0000000000000336_bib34","unstructured":"Dapena I, van de Star L, Groeneveld-van Beek E, et al. Bowman layer onlay grafting: new technique to flatten the corneal curvature and reduce progression in keratoconus. Presented at: European Society of Cataract and Refractive Surgeons Winter Meeting; Feb. 21-23, 2020; Marrakech, Morocco."}],"container-title":["Asia-Pacific Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2162098923001640?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2162098923001640?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.lww.com\/10.1097\/APO.0000000000000336","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T01:20:48Z","timestamp":1761873648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2162098923001640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,11]]},"references-count":34,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2020,11]]}},"alternative-id":["S2162098923001640"],"URL":"https:\/\/doi.org\/10.1097\/apo.0000000000000336","relation":{},"ISSN":["2162-0989"],"issn-type":[{"value":"2162-0989","type":"print"}],"subject":[],"published":{"date-parts":[[2020,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bowman Layer Transplantation\u2014A Review","name":"articletitle","label":"Article Title"},{"value":"Asia-Pacific Journal of Ophthalmology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1097\/APO.0000000000000336","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 Asia-Pacific Academy of Ophthalmology and Academy of Asia-Pacific Professors of Ophthalmology. Published by Elsevier Inc. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}