{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T09:25:37Z","timestamp":1790414737545,"version":"4.1.0"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1097\/bor.0b013e3282f154d1","type":"journal-article","created":{"date-parts":[[2009,3,4]],"date-time":"2009-03-04T21:56:08Z","timestamp":1236203768000},"page":"82-87","source":"Crossref","is-referenced-by-count":71,"title":["Beh\u00e7et's disease"],"prefix":"10.1097","volume":"20","author":[{"given":"Ilan","family":"Krause","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham","family":"Weinberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-15-20210128","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1097\/01.rhu.0000255693.75314.fd","article-title":"What does it take to diagnose Beh\u00e7et disease?","volume":"13","author":"Pandrea","year":"2007","journal-title":"J Clin Rheumatol"},{"key":"R2-15-20210128","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/s10067-006-0349-4","article-title":"Prevalence and clinical aspects of Beh\u00e7et's disease in the north of Israel","volume":"26","author":"Krause","year":"2007","journal-title":"Clin Rheumatol"},{"key":"R3-15-20210128","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1097\/RHU.0b013e3180645878","article-title":"Beh\u00e7et disease in adult Druze in north Israel: the influence of ethnic origin on disease expression and severity","volume":"13","author":"Rozenbaum","year":"2007","journal-title":"J Clin Rheumatol"},{"key":"R4-15-20210128","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/art.22500","article-title":"Epidemiology and clinical course of Beh\u00e7et's disease in the Reggio Emilia area of northern Italy: a seventeen-year population-based study","volume":"57","author":"Salvarani","year":"2007","journal-title":"Arthritis Rheum"},{"key":"R5-15-20210128","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/j.1365-2133.2006.07348.x","article-title":"TNF-alpha gene 1031 T\/C polymorphism in Turkish patients with Behcet's disease","volume":"155","author":"Akman","year":"2006","journal-title":"Br J Dermatol"},{"key":"R6-15-20210128","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1007\/s00296-005-0610-1","article-title":"Lack of association of tumor necrosis factor-alpha gene polymorphisms with disease susceptibility and severity in Behcet's disease","volume":"26","author":"Ates","year":"2006","journal-title":"Rheumatol Int"},{"key":"R7-15-20210128","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.humimm.2006.12.006","article-title":"Tumor necrosis factor gene polymorphisms in Tunisian patients with Behcet's disease","volume":"68","author":"Kamoun","year":"2007","journal-title":"Hum Immunol"},{"key":"R8-15-20210128","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.humimm.2006.11.010","article-title":"IL-10 genotype analysis in patients with Behcet's disease","volume":"68","author":"Wallace","year":"2007","journal-title":"Hum Immunol"},{"key":"R9-15-20210128","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/j.1399-0039.2006.00736.x","article-title":"Haplotype association of IL-8 gene with Behcet's disease","volume":"69","author":"Lee","year":"2007","journal-title":"Tissue Antigens"},{"key":"R10-15-20210128","first-page":"S79","article-title":"Endothelial nitric oxide synthase gene Glu298Asp polymorphism is associated with Behcet's disease","volume":"24","author":"Oksel","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"R11-15-20210128","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1001\/archopht.125.2.246","article-title":"Nitric oxide synthase and superoxide dismutase gene polymorphisms in Behcet disease","volume":"125","author":"Nakao","year":"2007","journal-title":"Arch Ophthalmol"},{"key":"R12-15-20210128","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1744-313X.2007.00655.x","article-title":"Analysis of CD28 and CTLA-4 gene polymorphisms in Turkish patients with Behcet's disease","volume":"34","author":"Gunesacar","year":"2007","journal-title":"Int J Immunogenet"},{"key":"R13-15-20210128","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1399-0039.2006.00742.x","article-title":"HLA-E*0101 and HLA-G*010101 reduce the risk of Behcet's disease","volume":"69","author":"Park","year":"2007","journal-title":"Tissue Antigens"},{"key":"R14-15-20210128","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1080\/03009740600759639","article-title":"Common FMF alleles may predispose to development of Behcet's disease with increased risk for venous thrombosis","volume":"36","author":"Rabinovich","year":"2007","journal-title":"Scand J Rheumatol"},{"key":"R15-15-20210128","first-page":"S71","article-title":"CD4(+)CD25(+) regulatory T cells in patients with Behcet's disease","volume":"24","author":"Hamzaoui","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"R16-15-20210128","doi-asserted-by":"crossref","first-page":"1534","DOI":"10.1038\/sj.jid.5700203","article-title":"Role of IL-12B promoter polymorphism in adamantiades-Behcet's disease susceptibility: a involvement of Th1 immunoreactivity against Streptococcus sanguinis antigen","volume":"126","author":"Yanagihori","year":"2006","journal-title":"J Invest Dermatol"},{"key":"R17-15-20210128","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1007\/s00296-005-0029-8","article-title":"Serum interleukin-18 levels in patients with Behcet's disease: is its expression associated with disease activity or clinical presentations?","volume":"26","author":"Musabak","year":"2006","journal-title":"Rheumatol Int"},{"key":"R18-15-20210128","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1365-3083.2006.01844.x","article-title":"Levels of IL-15 in serum and cerebrospinal fluid of patients with Behcet's disease","volume":"64","author":"Hamzaoui","year":"2006","journal-title":"Scand J Immunol"},{"key":"R19-15-20210128","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ajo.2006.04.016","article-title":"Intraocular cytokine environment in active Behcet uveitis","volume":"142","author":"Ahn","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"R20-15-20210128","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1016\/j.exer.2007.01.003","article-title":"Proteomic surveillance of autoimmunity in Behcet's disease with uveitis: selenium binding protein is a novel autoantigen in Behcet's disease","volume":"84","author":"Okunuki","year":"2007","journal-title":"Exp Eye Res"},{"key":"R21-15-20210128","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1080\/03009740600905380","article-title":"Expression of cytokines, chemokines, and chemokine receptors in oral ulcers of patients with Behcet's disease (BD) and recurrent aphthous stomatitis is Th1-associated, although Th2-association is also observed in patients with BD","volume":"35","author":"Dalghous","year":"2006","journal-title":"Scand J Rheumatol"},{"key":"R22-15-20210128","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1365-2230.2006.02284.x","article-title":"Pathergy reaction in different body areas in Behcet's disease","volume":"32","author":"Ozdemir","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"R23-15-20210128","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1111\/j.1365-4632.2006.02859.x","article-title":"The frequency of scarring after genital ulcers in Behcet's syndrome: a prospective study","volume":"45","author":"Mat","year":"2006","journal-title":"Int J Dermatol"},{"key":"R24-15-20210128","first-page":"146","article-title":"Histopathologic and direct immunofluorescence findings of the papulopustular lesions in Behcet's disease","volume":"16","author":"Ilknur","year":"2006","journal-title":"Eur J Dermatol"},{"key":"R25-15-20210128","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1007\/s10067-005-0070-8","article-title":"CNS involvement occurs more frequently in patients with Behcet's disease under cyclosporin A (CSA) than under other medications: results of a retrospective analysis of 117 cases","volume":"25","author":"Kotter","year":"2006","journal-title":"Clin Rheumatol"},{"key":"R26-15-20210128","first-page":"S65","article-title":"Silent neurological involvement in Behcet's disease","volume":"24","author":"Yesilot","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"R27-15-20210128","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1093\/rheumatology\/kei255","article-title":"The prevalence of headache in Behcet's syndrome","volume":"45","author":"Kidd","year":"2006","journal-title":"Rheumatology"},{"key":"R28-15-20210128","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/j.1468-2982.2005.01017.x","article-title":"Headache in Behcet's disease","volume":"26","author":"Aykutlu","year":"2006","journal-title":"Cephalalgia"},{"key":"R29-15-20210128","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s10067-006-0208-3","article-title":"Evaluation of left ventricular diastolic dysfunction with conventional and current Doppler techniques in Behcet's disease","volume":"25","author":"Baris","year":"2006","journal-title":"Clin Rheumatol"},{"key":"R30-15-20210128","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1111\/j.1540-8175.2006.00301.x","article-title":"Left and right ventricular function is impaired in Behcet's disease","volume":"23","author":"Yavuz","year":"2006","journal-title":"Echocardiography"},{"key":"R31-15-20210128","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.amjcard.2005.09.120","article-title":"Echocardiographic findings in patients with Behcet's disease","volume":"97","author":"Bozkurt","year":"2006","journal-title":"Am J Cardiol"},{"key":"R32-15-20210128","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1080\/07853890701204866","article-title":"Patients with Behcet's disease carry a higher risk for microvascular involvement in active disease period","volume":"39","author":"Gullu","year":"2007","journal-title":"Ann Med"},{"key":"R33-15-20210128","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1007\/s11605-006-0031-9","article-title":"Intestinal perforations in Behcet's disease","volume":"11","author":"Chou","year":"2007","journal-title":"J Gastrointest Surg"},{"key":"R34-15-20210128","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1093\/rheumatology\/kem034","article-title":"Anti-TNF therapy in the management of Behcet's disease: review and basis for recommendations","volume":"46","author":"Sfikakis","year":"2007","journal-title":"Rheumatology"},{"key":"R35-15-20210128","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1097\/01.rhu.0000249894.03016.de","article-title":"Behcet disease: recommendation for clinical management of mucocutaneous lesions","volume":"12","author":"Lin","year":"2006","journal-title":"J Clin Rheumatol"},{"key":"R36-15-20210128","first-page":"S83","article-title":"Lactobacilli lozenges in the management of oral ulcers of Behcet's syndrome","volume":"24","author":"Tasli","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"R37-15-20210128","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1111\/j.1468-3083.2006.01677.x","article-title":"Topical granulocyte colony-stimulating factor for the treatment of oral and genital ulcers of patients with Behcet's disease","volume":"20","author":"Bacanli","year":"2006","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R38-15-20210128","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1111\/j.1346-8138.2006.00128.x","article-title":"Oral zinc sulfate in the treatment of Behcet's disease: a double blind cross-over study","volume":"33","author":"Sharquie","year":"2006","journal-title":"J Dermatol"},{"key":"R39-15-20210128","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1093\/rheumatology\/kei165","article-title":"A double-blind trial of depot corticosteroids in Behcet's syndrome","volume":"45","author":"Mat","year":"2006","journal-title":"Rheumatology"},{"key":"R40-15-20210128","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/jca.20076","article-title":"Granulocytapheresis in patients with refractory ocular Behcet's disease","volume":"21","author":"Namba","year":"2006","journal-title":"J Clin Apheresis"},{"key":"R41-15-20210128","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.jdermsci.2006.11.008","article-title":"Homocysteine: an activity marker in Behcet's disease?","volume":"45","author":"Sarican","year":"2007","journal-title":"J Dermatol Sci"},{"key":"R42-15-20210128","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1515\/CCLM.2007.018","article-title":"Assessment of homocysteine, neopterin and nitric oxide levels in Behcet's disease","volume":"45","author":"Ozkan","year":"2007","journal-title":"Clin Chem Lab Med"},{"key":"R43-15-20210128","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1160\/TH05-10-0659","article-title":"Thrombophilic risk factors and homocysteine levels in Behcet's disease in eastern Spain and their association with thrombotic events","volume":"95","author":"Ricart","year":"2006","journal-title":"Throm Haemost"},{"key":"R44-15-20210128","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1007\/s10067-006-0513-x","article-title":"Oxidant\/antioxidant status in men with Behcet's disease","volume":"26","author":"Taysi","year":"2007","journal-title":"Clin Rheumatol"},{"key":"R45-15-20210128","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/j.1365-2230.2006.02330.x","article-title":"Detection of parvovirus B19 DNA in the lesional skin of patients with Behcet's disease","volume":"32","author":"Baskan","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"R46-15-20210128","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1002\/cbf.1227","article-title":"The relationship between serum prolactin levels and disease activity in patients with Behcet's disease","volume":"24","author":"Atasoy","year":"2006","journal-title":"Cell Biochem Funct"},{"key":"R47-15-20210128","doi-asserted-by":"crossref","first-page":"1849","DOI":"10.1007\/s10350-006-0706-z","article-title":"Anti-Saccharomyces cerevisiae antibody in intestinal Behcet's disease patients: relation to clinical course","volume":"49","author":"Choi","year":"2006","journal-title":"Dis Colon Rectum"},{"key":"R48-15-20210128","first-page":"S87","article-title":"Antisaccharomyces cerevisiae antibodies in Behcet's disease: a familial study","volume":"24","author":"Monselise","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"R49-15-20210128","first-page":"S104","article-title":"Increased titres of IgM antiheparan sulfate antibody in Behcet's disease","volume":"24","author":"Briani","year":"2006","journal-title":"Clin Exp Rheumatol"},{"key":"R50-15-20210128","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1111\/j.1365-2230.2006.02157.x","article-title":"Serum substance P and calcitonin gene-related peptide levels in Behcet's disease and their association with disease activity","volume":"31","author":"Aki","year":"2006","journal-title":"Clin Exp Dermatol"}],"container-title":["Current Opinion in Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/BOR.0b013e3282f154d1","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:45:33Z","timestamp":1786038333000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00002281-200801000-00015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/bor.0b013e3282f154d1","relation":{},"ISSN":["1040-8711"],"issn-type":[{"value":"1040-8711","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}