{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T05:50:09Z","timestamp":1793771409281,"version":"4.6.1"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1097\/bor.0b013e3283570238","type":"journal-article","created":{"date-parts":[[2012,7,25]],"date-time":"2012-07-25T08:38:23Z","timestamp":1343205503000},"page":"561-566","source":"Crossref","is-referenced-by-count":50,"title":["Mechanical stimuli and bone health"],"prefix":"10.1097","volume":"24","author":[{"given":"Angela M.","family":"Cheung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lora","family":"Giangregorio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-17-20210128","first-page":"126","article-title":"Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research.","volume":"100","author":"Caspersen","year":"1985","journal-title":"Public Health Rep"},{"key":"R3-17-20210128","first-page":"263","article-title":"Sclerostin: a novel target for intervention in the treatment of osteoporosis.","volume":"12","author":"Lewiecki","year":"2011","journal-title":"Discov Med"},{"key":"R4-17-20210128","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1210\/jc.2011-2152","article-title":"Sclerostin and its association with physical activity, age, gender, body composition, and bone mineral content in healthy adults.","volume":"97","author":"Amrein","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"R5-17-20210128","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.bone.2011.11.009","article-title":"Physical activity, body mass index and bone mineral density-associations in a prospective population-based cohort of women and men: the Canadian Multicentre Osteoporosis Study (CaMos).","volume":"50","author":"Langsetmo","year":"2012","journal-title":"Bone"},{"key":"R6-17-20210128","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s10654-010-9450-8","article-title":"Leisure time physical activity in adulthood is positively associated with bone mineral density 22 years later. The Tromso study.","volume":"25","author":"Morseth","year":"2010","journal-title":"Eur J Epidemiol"},{"key":"R7-17-20210128","first-page":"CD000333","article-title":"Exercise for preventing and treating osteoporosis in postmenopausal women.","volume":"7","author":"Howe","year":"2011","journal-title":"Cochrane Database Syst Rev"},{"issue":"3","key":"R8-17-20210128","first-page":"CD000333","article-title":"Exercise for preventing and treating osteoporosis in postmenopausal women.","author":"Bonaiuti","year":"2002","journal-title":"Cochrane Database Syst Rev"},{"key":"R9-17-20210128","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1097\/00002060-199801000-00015","article-title":"Exercise and regional bone mineral density in postmenopausal women: a meta-analytic review of randomized trials.","volume":"77","author":"Kelley","year":"1998","journal-title":"Am J Phys Med Rehabil"},{"key":"R10-17-20210128","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1210\/jc.2010-2284","article-title":"Independent and combined effects of calcium-vitamin D3 and exercise on bone structure and strength in older men: an 18-month factorial design randomized controlled trial.","volume":"96","author":"Kukuljan","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"R11-17-20210128","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1002\/jbmr.475","article-title":"Exercise training in obese older adults prevents increase in bone turnover and attenuates decrease in hip bone mineral density induced by weight loss despite decline in bone-active hormones.","volume":"26","author":"Shah","year":"2011","journal-title":"J Bone Miner Res"},{"key":"R12-17-20210128","first-page":"1634","article-title":"Have the DXA-based exercise studies seriously underestimated the effects of mechanical loading on bone J Bone Miner R","volume":"14","author":"Jarvinen","year":"1999","journal-title":"es"},{"key":"R13-17-20210128","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1001\/jama.299.12.1468","article-title":"Osteoporosis and fracture: missing the bridge","volume":"299","author":"Cheung","year":"2008","journal-title":"JAMA"},{"key":"R14-17-20210128","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.bone.2009.10.041","article-title":"Associations between leisure physical activity participation and cortical bone mass and geometry at the radius and tibia in a Canadian cohort of postmenopausal women.","volume":"46","author":"Hamilton","year":"2010","journal-title":"Bone"},{"key":"R15-17-20210128","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.bone.2010.05.003","article-title":"Muscle power and physical activity are associated with bone strength in older men: the Osteoporotic Fractures in Men study.","volume":"47","author":"Cousins","year":"2010","journal-title":"Bone"},{"key":"R16-17-20210128","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00198-011-1734-7","article-title":"The effect of exercise on pQCT parameters of bone structure and strength in postmenopausal women: a systematic review and meta-analysis of randomized controlled trials.","volume":"23","author":"Polidoulis","year":"2012","journal-title":"Osteoporos Int"},{"key":"R17-17-20210128","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1016\/j.annepidem.2008.08.007","article-title":"The association between physical activity and osteoporotic fractures: a review of the evidence and implications for future research.","volume":"18","author":"Moayyeri","year":"2008","journal-title":"Ann Epidemiol"},{"key":"R18-17-20210128","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.bone.2010.06.023","article-title":"The association between physical activity in different domains of life and risk of osteoporotic fractures.","volume":"47","author":"Moayyeri","year":"2010","journal-title":"Bone"},{"key":"R19-17-20210128","doi-asserted-by":"crossref","first-page":"2332","DOI":"10.1002\/jbmr.143","article-title":"Physical activity slows femoral bone loss but promotes wrist fractures in postmenopausal women: a 15-year follow-up of the OSTPRE study.","volume":"25","author":"Rikkonen","year":"2010","journal-title":"J Bone Miner Res"},{"key":"R21-17-20210128","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1071\/NB10056","article-title":"Exercise to prevent falls in older adults: an updated meta-analysis and best practice recommendations.","volume":"22","author":"Sherrington","year":"2011","journal-title":"N S W Public Health Bull"},{"key":"R23-17-20210128","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1038\/35088122","article-title":"Anabolism. Low mechanical signals strengthen long bones.","volume":"412","author":"Rubin","year":"2001","journal-title":"Nature"},{"key":"R24-17-20210128","first-page":"7","article-title":"Tiny vibrations may help muscle, bone, and balance.","volume":"14","year":"2006","journal-title":"Harv Womens Health Watch"},{"key":"R25-17-20210128","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.arr.2008.07.004","article-title":"Effects of whole body vibration on the skeleton and other organ systems in man and animal models: what we know and what we need to know.","volume":"7","author":"Prisby","year":"2008","journal-title":"Ageing Res Rev"},{"key":"R26-17-20210128","first-page":"193","article-title":"Reporting whole-body vibration intervention studies: recommendations of the International Society of Musculoskeletal and Neuronal Interactions.","volume":"10","author":"Rauch","year":"2010","journal-title":"J Musculoskelet Neuronal Interact"},{"key":"R27-17-20210128","first-page":"3","article-title":"Is bone formation induced by high-frequency mechanical signals modulated by muscle activity J Musculoskelet Neuronal I","volume":"10","author":"Judex","year":"2010","journal-title":"nteract"},{"key":"R28-17-20210128","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1038\/nrrheum.2009.239","article-title":"Mechanical signals as anabolic agents in bone.","volume":"6","author":"Ozcivici","year":"2010","journal-title":"Nat Rev Rheumatol"},{"key":"R29-17-20210128","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1007\/s00198-010-1228-z","article-title":"Effect of whole-body vibration on BMD: a systematic review and meta-analysis.","volume":"21","author":"Slatkovska","year":"2010","journal-title":"Osteoporos Int"},{"key":"R30-17-20210128","doi-asserted-by":"crossref","first-page":"680","DOI":"10.7326\/0003-4819-155-10-201111150-00006","article-title":"Whole-body vibration therapy for osteoporosis: state of the science.","volume":"155","author":"Wysocki","year":"2011","journal-title":"Ann Intern Med"},{"key":"R31-17-20210128","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.maturitas.2010.01.013","article-title":"The effect of whole body vibration exposure on muscle or bone morphology and function in older adults: a systematic review of the literature.","volume":"66","author":"Mikhael","year":"2010","journal-title":"Maturitas"},{"key":"R32-17-20210128","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1177\/0269215511405078","article-title":"The effects of whole body vibration therapy on bone mineral density and leg muscle strength in older adults: a systematic review and meta-analysis.","volume":"25","author":"Lau","year":"2011","journal-title":"Clin Rehabil"},{"key":"R33-17-20210128","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1089\/acm.2010.0691","article-title":"Using whole-body vibration training in patients affected with common neurological diseases: a systematic literature review.","volume":"18","author":"del Pozo-Cruz B, Adsuar","year":"2012","journal-title":"J Altern Complement Med"},{"key":"R34-17-20210128","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1249\/MSS.0b013e318202f3d3","article-title":"Effects of whole-body vibration training on different devices on bone mineral density.","volume":"43","author":"Von Stengel","year":"2011","journal-title":"Med Sci Sports Exerc"},{"key":"R35-17-20210128","doi-asserted-by":"crossref","first-page":"668","DOI":"10.7326\/0003-4819-155-10-201111150-00005","article-title":"Effect of 12 months of whole-body vibration therapy on bone density and structure in postmenopausal women: a randomized trial.","volume":"155","author":"Slatkovska","year":"2011","journal-title":"Ann Intern Med"},{"key":"R36-17-20210128","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00198-010-1215-4","article-title":"Effects of whole body vibration on bone mineral density and falls: results of the randomized controlled ELVIS study with postmenopausal women.","volume":"22","author":"von Stengel","year":"2011","journal-title":"Osteoporos Int"},{"key":"R37-17-20210128","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1097\/PHM.0b013e3181f71063","article-title":"The effect of 8 mos of twice-weekly low- or higher intensity whole body vibration on risk factors for postmenopausal hip fracture.","volume":"89","author":"Beck","year":"2010","journal-title":"Am J Phys Med Rehabil"},{"key":"R38-17-20210128","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1002\/jbmr.181","article-title":"The effects of whole-body vibration training and vitamin D supplementation on muscle strength, muscle mass, and bone density in institutionalized elderly women: a 6-month randomized, controlled trial.","volume":"26","author":"Verschueren","year":"2011","journal-title":"J Bone Miner Res"}],"container-title":["Current Opinion in Rheumatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/BOR.0b013e3283570238","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T23:04:13Z","timestamp":1620947053000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00002281-201209000-00017"}},"subtitle":["what is the evidence?"],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/bor.0b013e3283570238","relation":{},"ISSN":["1040-8711"],"issn-type":[{"value":"1040-8711","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}