{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:59:32Z","timestamp":1770137972927,"version":"3.49.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,11]]},"abstract":"<jats:sec>\n            <jats:title>Objectives:<\/jats:title>\n            <jats:p>To compare the risk of major complications after either minimally invasive plate osteosynthesis (MIPO) or intramedullary nailing (IMN) of humeral shaft fractures.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Design:<\/jats:title>\n            <jats:p>Retrospective, case-match controlled study.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Setting:<\/jats:title>\n            <jats:p>A major metropolitan tertiary referral trauma center in Australia.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Patients:<\/jats:title>\n            <jats:p>Thirty patients with fractures of the humeral shaft.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Intervention:<\/jats:title>\n            <jats:p>Either MIPO or IMN were performed on 15 patients each with traumatic humeral shaft fractures.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Primary Outcome Measure:<\/jats:title>\n            <jats:p>The cumulative risk of 3 major complications associated with these procedures: nonunion, infection, and iatrogenic radial nerve injury.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>An overall major complication rate of 53% was observed in the patients treated with IMN; one complication (7%) was identified in those managed with humeral MIPO, a nonunion. Complications after IMN included 4 patients (27%) with nonunion, 3 patients (20%) with iatrogenic radial nerve injuries, and 1 patient (7%) with a wound infection. Statistical analysis revealed a significant between-group difference (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.01) in the cumulative rate of major complications. When each of these complications was considered independently, no statistically significant difference was demonstrated.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>This study suggests that humeral MIPO results in a significantly lower pooled major complication rate than that of IMN, and it should therefore be considered an attractive alternative to IMN in those patients requiring surgical stabilization of a traumatic humeral shaft fracture.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Level of Evidence:<\/jats:title>\n            <jats:p>Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/bot.0000000000000643","type":"journal-article","created":{"date-parts":[[2016,10,22]],"date-time":"2016-10-22T11:51:57Z","timestamp":1477137117000},"page":"612-617","source":"Crossref","is-referenced-by-count":23,"title":["Case-Match Controlled Comparison of Minimally Invasive Plate Osteosynthesis and Intramedullary Nailing for the Stabilization of Humeral Shaft Fractures"],"prefix":"10.1097","volume":"30","author":[{"given":"Gareth","family":"Davies","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Royal Brisbane and Women's Hospital, Brisbane, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Yeo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Royal Brisbane and Women's Hospital, Brisbane, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahendrakumar","family":"Meta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erik","family":"Hohmann","sequence":"additional","affiliation":[{"name":"Musculoskeletal Research Unit, Central Queensland University, Rockhampton, Australia;"},{"name":"School of Medicine, University of Queensland, Brisbane, Australia; 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