{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T11:10:30Z","timestamp":1785409830412,"version":"3.56.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>Posttraumatic bone defects in the setting of severe open injuries of the lower extremity present a significant challenge for orthopaedic trauma surgeons. The induced membrane technique, also known as the Masquelet technique, has been shown to be generally successful in achieving bony union. This video demonstrates the use of the Masquelet technique for a large (18 cm) femoral defect.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>The Masquelet technique is a 2-stage process. The first stage involves debridement of all devitalized tissue, using open reduction and internal fixation, and placement of a cement spacer with or without antibiotics. In the second stage, which is performed at least 6 weeks after the first, the spacer is removed and the resulting void is filled with bone graft.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>This surgical case video reviews the relevant patient injury presentation, initial management, and indications for the Masquelet technique. The second stage of the Masquelet technique is featured in this video.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>The Masquelet technique is a generally reliable method for treating large segmental bone defects. In addition, this relatively simple technique is suitable for both infected and noninfected cases.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/bot.0000000000000899","type":"journal-article","created":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T15:31:25Z","timestamp":1499787085000},"page":"S21-S22","source":"Crossref","is-referenced-by-count":20,"title":["Segmental Bone Defect Treated With the Induced Membrane Technique"],"prefix":"10.1097","volume":"31","author":[{"given":"Sanjit R.","family":"Konda","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY; and"},{"name":"Jamaica Hospital Medical Center, Queens, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Gage","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY; and"},{"name":"Jamaica Hospital Medical Center, Queens, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Fisher","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY; and"},{"name":"Jamaica Hospital Medical Center, Queens, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth A.","family":"Egol","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, NYU Hospital for Joint Diseases, New York, NY; and"},{"name":"Jamaica Hospital Medical Center, Queens, NY."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20231017","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/adhm.201500793","article-title":"Biomaterial-stabilized soft tissue healing for healing of critical-sized bone defects: the Masquelet technique","volume":"5","author":"Tarchala","year":"2016","journal-title":"Adv Healthc Mater."},{"key":"R2-20231017","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.ocl.2009.07.011","article-title":"The concept of induced membrane for reconstruction of long bone defects","volume":"41","author":"Masquelet","year":"2010","journal-title":"Orthop Clin North Am."},{"key":"R3-20231017","first-page":"e188","article-title":"Reconstruction of long bone infections using the induced membrane technique","volume":"30","author":"Mauffrey","year":"2016","journal-title":"J Orthop Trauma."},{"key":"R4-20231017","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s13037-015-0079-0","article-title":"Innovative strategies for the management of long bone infection: a review of the Masquelet technique","volume":"9","author":"Chadayammuri","year":"2015","journal-title":"Patient Saf Surg."},{"key":"R5-20231017","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1055\/s-0029-1214163","article-title":"Reconstruction of osteomyelitis defects","volume":"23","author":"Dinh","year":"2009","journal-title":"Semin Plast Surg."},{"key":"R6-20231017","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1016\/j.injury.2007.02.012","article-title":"Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions?","volume":"38","author":"Sen","year":"2007","journal-title":"Injury"},{"key":"R7-20231017","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1302\/0301-620X.95B9.31756","article-title":"The viability of cells obtained using the Reamer-Irrigator-Aspirator system and in bone graft from the iliac crest","volume":"95-B","author":"Uppal","year":"2013","journal-title":"Bone Joint J."},{"key":"R8-20231017","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00132-016-3305-2","article-title":"Tibiadefekt- und Infektpseudarthrosen [in German]","volume":"46","author":"Moghaddam","year":"2017","journal-title":"Orthopade"},{"key":"R9-20231017","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1097\/BOT.0000000000000614","article-title":"Membrane induced osteogenesis in the management of posttraumatic bone defects","volume":"30","author":"Azi","year":"2016","journal-title":"J Orthop Trauma."},{"key":"R10-20231017","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.otsr.2011.11.001","article-title":"Treatment of posttraumatic bone defects by the induced membrane technique","volume":"98","author":"Karger","year":"2012","journal-title":"Orthop Traumatol Surg Res."},{"key":"R11-20231017","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1097\/BOT.0000000000000338","article-title":"Treatment of bone loss with the induced membrane technique","volume":"29","author":"Taylor","year":"2015","journal-title":"J Orthop Trauma."}],"container-title":["Journal of Orthopaedic Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00005131-201708003-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T15:00:31Z","timestamp":1697554831000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00005131-201708003-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":11,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017]]}},"URL":"https:\/\/doi.org\/10.1097\/bot.0000000000000899","relation":{},"ISSN":["0890-5339"],"issn-type":[{"value":"0890-5339","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]}}}