{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T07:26:24Z","timestamp":1790753184005,"version":"4.1.0"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11]]},"abstract":"\n Objectives:<\/jats:title>\n To identify factors associated with the development of prolonged pain after hip fracture surgery.<\/jats:p>\n <\/jats:sec>\n \n Design:<\/jats:title>\n Secondary analysis of a randomized controlled trial.<\/jats:p>\n <\/jats:sec>\n \n Setting:<\/jats:title>\n Eighty hospitals in 10 countries.<\/jats:p>\n <\/jats:sec>\n \n Patients\/Participants:<\/jats:title>\n One thousand four hundred forty-one hip fracture patients in the HEALTH trial.<\/jats:p>\n <\/jats:sec>\n \n Interventions:<\/jats:title>\n Total hip arthroplasty or hemiarthroplasty.<\/jats:p>\n <\/jats:sec>\n \n Main Outcome Measures:<\/jats:title>\n Moderate-to-severe pain (at least 2 activities on the Western Ontario and McMaster Universities Osteoarthritis questionnaire pain subscale with scores \u22652) at 12 and 24 months after hip arthroplasty.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Of 840 and 726 patients with complete baseline data and outcomes at 1-year and 2-year follow-up, 96 (11.4%) and 80 (11.0%) reported moderate-to-severe pain, respectively. An increased risk of pain at both 1 and 2 years after surgery was associated with reporting moderate-to-severe hip pain before fracture [absolute risk increase (ARI) 15.3%, 95% confidence interval (CI) 6.44%\u201324.35%; ARI 12.5%, 95% CI 2.85%\u201322.12%, respectively] and prefracture opioid use (ARI 15.6%, 95% CI 5.41%\u201325.89%; ARI 21.1%; 95% CI 8.23%\u201334.02%, respectively). Female sex was associated with an increased risk of persistent pain at 1 year (ARI 6.2%, 95% CI 3.53%\u20138.84%). A greater risk of persistent pain at 2 years was associated with younger age (\u226479-year-old; ARI 6.3%; 95% CI 2.67%\u20139.91%) and higher prefacture functional status (ARI 10.7%; 95% CI 3.80%\u201317.64%).<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n Among hip fracture patients undergoing arthroplasty, approximately one in 10 will experience moderate-to-severe pain up to 2 years after surgery. Younger age, female sex, higher functioning prefracture, living with hip pain prefracture, and use of prescription opioids were predictive of persistent pain.<\/jats:p>\n <\/jats:sec>\n \n Level of Evidence:<\/jats:title>\n Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.<\/jats:p>\n <\/jats:sec>","DOI":"10.1097\/bot.0000000000001929","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T13:00:22Z","timestamp":1601989222000},"page":"S55-S63","source":"Crossref","is-referenced-by-count":14,"title":["Predictors of Long-Term Pain After Hip Arthroplasty in Patients With Femoral Neck Fractures: A Cohort Study"],"prefix":"10.1097","volume":"34","author":[{"given":"Atefeh","family":"Noori","sequence":"first","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton,Ontario, Canada;"},{"name":"The Michael G. 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