{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,12]],"date-time":"2026-07-12T02:05:15Z","timestamp":1783821915152,"version":"3.55.0"},"reference-count":34,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,11]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Hip fractures are recognized as one of the most devastating injuries impacting older adults because of the complications that follow. Mortality rates postsurgery can range from 14% to 58% within one year of fracture. We aimed to identify factors associated with increased risk of mortality within 24 months of a femoral neck fracture in patients aged \u226550 years enrolled in the FAITH and HEALTH trials.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Two multivariable Cox proportional hazards regressions were used to investigate potential prognostic factors that may be associated with mortality within 90 days and 24 months of hip fracture.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Ninety-one (4.1%) and 304 (13.5%) of 2247 participants died within 90 days and 24 months of suffering a femoral neck fracture, respectively. Older age (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001), lower body mass index (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.002), American Society of Anesthesiologists (ASA) class III\/IV\/V (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.004), use of an ambulatory aid before femoral neck fracture (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001), and kidney disease (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001) were associated with a higher risk of mortality within 24 months of femoral neck fracture. Older age (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.03), lower body mass index (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.02), use of an ambulatory aid before femoral neck fracture (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001), and having a comorbidity (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.04) were associated with a higher risk of mortality within 90 days of femoral neck fracture.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Our analysis found that factors that are indicative of a poorer health status were associated with a higher risk of mortality within 24 months of femoral neck fracture. We did not find a difference in treatment methods (internal fixation vs. joint arthroplasty) on the risk of mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Level of Evidence:<\/jats:title>\n            <jats:p>Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/bot.0000000000001937","type":"journal-article","created":{"date-parts":[[2020,10,6]],"date-time":"2020-10-06T13:00:30Z","timestamp":1601989230000},"page":"S15-S21","source":"Crossref","is-referenced-by-count":25,"title":["Factors Associated With Mortality After Surgical Management of Femoral Neck Fractures"],"prefix":"10.1097","volume":"34","author":[{"given":"Sofia","family":"Bzovsky","sequence":"first","affiliation":[{"name":"Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianne","family":"Comeau-Gauthier","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emil H.","family":"Schemitsch","sequence":"additional","affiliation":[{"name":"Department of Surgery, University of Western Ontario, London, ON, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Swiontkowski","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diane","family":"Heels-Ansdell","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frede","family":"Frihagen","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Oslo University Hospital, Oslo, Norway."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada;"},{"name":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheila","family":"Sprague","sequence":"additional","affiliation":[{"name":"Division of Orthopaedic Surgery, Department of Surgery, McMaster University, Hamilton, ON, Canada;"},{"name":"Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the FAITH and HEALTH Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20230828","doi-asserted-by":"crossref","first-page":"15","DOI":"10.4103\/0019-5413.73656","article-title":"Epidemiology of hip fracture: worldwide geographic variation","volume":"45","author":"Dhanwal","year":"2011","journal-title":"Indian J Orthop."},{"key":"R2-20230828","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF01623184","article-title":"Hip fractures in the elderly: a world-wide projection","volume":"2","author":"Cooper","year":"1992","journal-title":"Osteoporos Int."},{"key":"R3-20230828","doi-asserted-by":"crossref","first-page":"54","DOI":"10.3109\/17453674.2013.878831","article-title":"Similar mortality rates in hip fracture patients over the past 31 Years: a systematic review of RCTs","volume":"85","author":"Mundi","year":"2014","journal-title":"Acta Orthop."},{"key":"R4-20230828","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1046\/j.1532-5415.2002.50455.x","article-title":"Mortality, disability, and nursing home use for persons with and without hip fracture: a population-based study","volume":"50","author":"Leibson","year":"2002","journal-title":"J Am Geriatr Soc."},{"key":"R5-20230828","doi-asserted-by":"crossref","first-page":"402","DOI":"10.5312\/wjo.v5.i4.402","article-title":"Complications of hip fractures: a review","volume":"5","author":"Carpintero","year":"2014","journal-title":"World J Orthop."},{"key":"R6-20230828","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1177\/2151458510378105","article-title":"The 1-year mortality of patients treated in a hip fracture Program for elders","volume":"1","author":"Schnell","year":"2010","journal-title":"Geriatr Orthop Surg Rehabil."},{"key":"R7-20230828","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1016\/S0140-6736(17)30066-1","article-title":"Fixation using Alternative Implants for the Treatment of Hip fractures (FAITH) Investigators. 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