{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T11:03:03Z","timestamp":1794654183393,"version":"4.9.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:sec>\n            <jats:title>Objectives:<\/jats:title>\n            <jats:p>To evaluate the effect of a traditional \u201ccenter-center\u201d end point for distal tibia nailing in comparison with a lateral-of-center end point on fracture malalignment in a cadaver model.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Nine matched pairs of human cadaveric lower-extremity specimens were used to model the effect of nail end point on fracture alignment in extra-articular distal tibia fractures. After simulation of the fracture through a standardized osteotomy, 1 member of each pair was fixed with an intramedullary nail using a \u201ccenter-center\u201d end point, whereas a lateral-of-center end point was used for the other member of the pair. Specimens were stripped of soft tissue, and digital calipers were used to measure fracture translation and gap medially, laterally, anteriorly, and posteriorly. Coronal plane angulation at each fracture was measured on the final mortise image.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>The average coronal angulation was 7.0 degrees of valgus (with a SD of 4.1) in central-end point specimens versus 0.2 degrees of valgus (SD = 1.5) in lateral-end point specimens (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001). Lateral-end point specimens also demonstrated significantly less fracture gap medially (mean 0.2 vs. 3.1 mm for central-end point specimens, <jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001), anteriorly (mean 0.1 vs. 1.3 mm, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.003), and posteriorly (mean 0.3 vs. 2.2 mm, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.003). Lateral-end point specimens also showed less lateral translation (mean 0.6 vs. 1.6 mm, <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.006).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Lateral-of-center nail end points may help surgeons restore native alignment in extra-articular distal tibia fractures and avoid valgus malalignment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/bot.0000000000002345","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T00:05:59Z","timestamp":1641773159000},"page":"400-405","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["A Critical Analysis of Lateral Versus Central Endpoint in Distal Tibia Nailing: Does It Affect Alignment?"],"prefix":"10.1097","volume":"36","author":[{"given":"Dane J.","family":"Brodke","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Upfill-Brown","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai K.","family":"Devana","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily K.","family":"Eichenlaub","sequence":"additional","affiliation":[{"name":"Musculoskeletal Education and Research Center, A Division of Globus Medical, Inc, Audubon, PA; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan M.","family":"Mahoney","sequence":"additional","affiliation":[{"name":"Musculoskeletal Education and Research Center, A Division of Globus Medical, Inc, Audubon, PA; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mattan R.","family":"Orbach","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Science and Health Systems, Drexel University, Philadelphia, PA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brandon S.","family":"Bucklen","sequence":"additional","affiliation":[{"name":"Musculoskeletal Education and Research Center, A Division of Globus Medical, Inc, Audubon, PA; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin V.","family":"Kelley","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik N.","family":"Mayer","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan Y.","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of California Los Angeles, Los Angeles, CA;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250614","first-page":"349","article-title":"Osteosynthesis of 245 tibial shaft fractures: early and late complications","volume":"35","author":"Bilat","year":"2004","journal-title":"Injury"},{"key":"R2-20250614","doi-asserted-by":"crossref","first-page":"174","DOI":"10.2106\/00004623-199802000-00004","article-title":"Closed fractures of the tibial shaft. 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