{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T19:06:26Z","timestamp":1767035186822,"version":"3.44.0"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n            <jats:title>OBJECTIVES:<\/jats:title>\n            <jats:p>To identify practices for treating interprosthetic femur fractures (IFFs) and determine factors that positively affect patient outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Design:<\/jats:title>\n            <jats:p>Retrospective cohort study.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Setting:<\/jats:title>\n            <jats:p>Fifteen trauma centers in the United States.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Patient Selection Criteria:<\/jats:title>\n            <jats:p>Patients aged 50\u201390 years who underwent operative fixation of an AO\/OTA 32 A-B-C type IFF fracture from 2011 to 2021 were included. Patients who underwent revision arthroplasty at the time of fixation or were nonambulatory were excluded.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Outcome Measures and Comparisons:<\/jats:title>\n            <jats:p>The primary outcome was union rate. Secondary outcomes included postoperative complications, revision surgery, mortality, and change in ambulation status. Univariate analyses using chi-square tests, Fisher exact tests, and analysis of variance were performed to detect associations between demographic, injury, and surgical characteristics with postoperative outcomes.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>One hundred thirty-nine patients were included, with 110 (79%) women and median age 78 [range, 57\u201390]. Distal one-third fractures were most common, 68% (N = 95). One hundred eighteen (85%) patients were treated with a lateral plate, 8% (N = 11) were treated with nail\u2013plate combination and 7% (N = 10) were treated with dual plates. The median time to full-weight bearing was 2.5 months. Dual plate combination was associated with the fastest time to full-weight bearing (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.048) at 2 weeks. In total, 61% (n = 85) of patients returned to baseline ambulation status (100% [11] IMN\u2013plate, 60% [71] lateral plate, and 25% [3] dual plate) with patients treated with nail\u2013plate had higher rates of return to baseline function (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.009). The overall mortality rate was 13% and associated with greater than 1 comorbidity (<jats:italic toggle=\"yes\">P<\/jats:italic> = 0.022).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>A spanning lateral plate was the most common fixation of IFF. Patients with dual fixation were more likely to return to baseline ambulatory status, particularly those with intramedullary nail\u2013plate combination. The mortality rate at 1 year was 11% and comorbidity burden was associated with higher risk of mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>LEVEL OF EVIDENCE:<\/jats:title>\n            <jats:p>Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/bot.0000000000003003","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T14:00:15Z","timestamp":1746626415000},"page":"462-469","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Interprosthetic Femur Fractures: A Multicenter Retrospective Study"],"prefix":"10.1097","volume":"39","author":[{"given":"Samuel","family":"Landoch","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, University of Kentucky, Lexington, KY, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey A.","family":"Foster","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, Atrium Health Wake Forest Baptist, Winston Salem, NS, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5969-8018","authenticated-orcid":false,"given":"Lisa","family":"Cannada","sequence":"additional","affiliation":[{"name":"Novant Health Orthopaedic Fracture Clinic, Charlotte, NC, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William T.","family":"Obremskey","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan","family":"Will","sequence":"additional","affiliation":[{"name":"Department of Orthopedics and Sports Medicine, Multicare Health Systems, Tacoma, WA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Brianna","family":"Fram","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yale University, New Haven, CT, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon C.","family":"Mears","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, University of Florida, Gaineseville, FL, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey B.","family":"Stambough","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjamin M.","family":"Stronach","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harrison","family":"Brown","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arkansas for Medical Sciences, Little Rock, AR, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason J.","family":"Halvorson","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, Atrium Health Wake Forest Baptist, Winston Salem, NS, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nicholas","family":"Andring","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, Atrium Health Wake Forest Baptist, Winston Salem, NS, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalie","family":"Marenghi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Rehabilitation, Atrium Health Wake Forest Baptist, Winston Salem, NS, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niloofar","family":"Dehghan","sequence":"additional","affiliation":[{"name":"The CORE Institute, Phoenix, AZ, USA;"},{"name":"Department of Orthopaedic Surgery, University of Arizona College of Medicine Phoenix, Phoenix, AZ, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tony","family":"Huynh","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, University of Arizona College of Medicine Phoenix, Phoenix, AZ, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Ryan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Tufts Medical Center, Boston, MA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guy","family":"Guenthner","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Tufts Medical Center, Boston, MA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron","family":"Shiinoki","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Tufts Medical Center, Boston, MA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacob M.","family":"Fischman","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Tufts Medical Center, Boston, MA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elsa","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andres F.","family":"Moreno-Diaz","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksander","family":"Mika","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farhan","family":"Chowdry","sequence":"additional","affiliation":[{"name":"Novant Health Orthopaedic Fracture Clinic, Charlotte, NC, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of North Carolina, Chapel Hill, NC, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zohair","family":"Zaidi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, University of North Carolina, Chapel Hill, NC, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna N.","family":"Miller","sequence":"additional","affiliation":[{"name":"Orthopedics, Washington University, St. Louis, MO, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Gutbrod","sequence":"additional","affiliation":[{"name":"Orthopedics, Washington University, St. Louis, MO, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin","family":"Hofer","sequence":"additional","affiliation":[{"name":"TriStar Skyline Medical Center, Nashville, TN, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carmen","family":"Quatman","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics, Ohio State University, Columbus, OH, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jarrod","family":"Dumpe","sequence":"additional","affiliation":[{"name":"Atrium Health Navicent, Orthopaedic Trauma Institute, Macon, GA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Denisiuk","sequence":"additional","affiliation":[{"name":"Atrium Health Navicent, Orthopaedic Trauma Institute, Macon, GA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marylou","family":"Sutherland","sequence":"additional","affiliation":[{"name":"Atrium Health Navicent, Orthopaedic Trauma Institute, Macon, GA, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heidi","family":"Israel","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Saint Louis University School of Medicine, St. Louis, MO, USA; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul E.","family":"Matuszewski","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery and Sports Medicine, University of Kentucky, Lexington, KY, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arun","family":"Aneja","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA, USA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20250904","first-page":"1","article-title":"Hospitalization for total hip replacement among inpatients aged 45 and over: United States, 2000-2010","volume":"186","author":"Wolford","year":"2015","journal-title":"NCHS Data Brief"},{"key":"R2-20250904","first-page":"1","article-title":"Hospitalization for total knee replacement among inpatients aged 45 and over: United States, 2000-2010","volume":"210","author":"Williams","year":"2015","journal-title":"NCHS Data Brief"},{"key":"R3-20250904","doi-asserted-by":"crossref","first-page":"1455","DOI":"10.2106\/JBJS.17.01617","article-title":"Projected volume of primary total joint arthroplasty in the U.S., 2014 to 2030","volume":"100","author":"Sloan","year":"2018","journal-title":"J Bone Joint Surg Am."},{"key":"R4-20250904","first-page":"1","article-title":"Interprosthetic femur fractures: systematic review","volume":"3","author":"Golub","year":"2022","journal-title":"J Orthop Exp Innovation"},{"key":"R5-20250904","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1097\/BOT.0b013e3181d73508","article-title":"Interprosthetic femoral fractures","volume":"24","author":"Mamczak","year":"2010","journal-title":"J Orthop Trauma"},{"key":"R6-20250904","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.arth.2008.10.008","article-title":"Interprosthetic fractures of the femur: treatment with a single-locked plate","volume":"25","author":"Sah","year":"2010","journal-title":"J Arthroplasty"},{"key":"R7-20250904","doi-asserted-by":"crossref","first-page":"e63","DOI":"10.5435\/JAAOS-D-15-00664","article-title":"Management of interprosthetic femur fractures","volume":"25","author":"Scolaro","year":"2017","journal-title":"J Am Acad Orthop Surg."},{"key":"R8-20250904","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.otsr.2011.07.009","article-title":"Interprosthetic femoral fractures: analysis of 14 cases. Proposal for an additional grade in the Vancouver and SoFCOT classifications","volume":"97","author":"Soenen","year":"2011","journal-title":"Orthop Traumatol Surg Res."},{"key":"R12-20250904","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s12306-023-00808-8","article-title":"Interimplant femoral fracture: analysis of risk factors","volume":"108","author":"Caldaria","year":"2024","journal-title":"Musculoskelet Surg."},{"key":"R9-20250904","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1302\/2058-5241.5.200003","article-title":"Postoperative periprosthetic femoral fracture around total hip replacements: current concepts and clinical outcomes","volume":"5","author":"Ramavath","year":"2020","journal-title":"EFORT Open Rev."},{"key":"R10-20250904","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.otsr.2018.07.026","article-title":"Interprosthetic femoral fractures: morbidity and mortality in a retrospective, multicenter study","volume":"105","author":"Bonnevialle","year":"2019","journal-title":"Orthop Traumatol Surg Res."},{"key":"R11-20250904","doi-asserted-by":"crossref","first-page":"396","DOI":"10.2106\/JBJS.16.00499","article-title":"Subsequent total joint arthroplasty after primary total knee or hip arthroplasty: a 40-year population-based study","volume":"99","author":"Sanders","year":"2017","journal-title":"J Bone Joint Surg Am."},{"key":"R13-20250904","first-page":"35","article-title":"Radiographic risk factors for interprosthetic femur fractures","volume":"37","author":"Lipof","year":"2017","journal-title":"Iowa Orthop J."},{"key":"R25-20250904","doi-asserted-by":"crossref","first-page":"1918","DOI":"10.1016\/j.injury.2021.04.014","article-title":"Interprosthetic femoral fractures managed with modern distal femoral locking plates: 10 years' experience at a UK major trauma centre","volume":"52","author":"Mittal","year":"2021","journal-title":"Injury"},{"key":"R14-20250904","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jor.2022.07.013","article-title":"A systematic review of the surgical outcomes of interprosthetic femur fractures","volume":"33","author":"Rao","year":"2022","journal-title":"J Orthop."},{"key":"R15-20250904","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1097\/BOT.0000000000001749","article-title":"Supplemental fixation of supracondylar distal femur fractures: a biomechanical comparison of dual-plate and plate-nail constructs","volume":"34","author":"Wright","year":"2020","journal-title":"J Orthop Trauma"},{"key":"R16-20250904","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.injury.2022.11.035","article-title":"Nail plate combination in fractures of the distal femur in the elderly: a new paradigm for optimum fixation and early mobilization?","volume":"54","author":"Kontakis","year":"2023","journal-title":"Injury"},{"key":"R17-20250904","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1007\/s11999-010-1530-2","article-title":"Mortality after distal femur fractures in elderly patients","volume":"469","author":"Streubel","year":"2011","journal-title":"Clin Orthop Relat Res."},{"key":"R18-20250904","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1007\/s00264-018-4132-3","article-title":"Functional outcomes and mortality in geriatric and fragility hip fractures-results of an integrated, multidisciplinary model experienced by the \u201cFlorence hip fracture unit\u201d","volume":"43","author":"Civinini","year":"2019","journal-title":"Int Orthop."},{"key":"R19-20250904","doi-asserted-by":"crossref","first-page":"402","DOI":"10.14336\/AD.2016.1228","article-title":"One-year readmission risk and mortality after hip fracture surgery: a national population-based study in Taiwan","volume":"8","author":"Lee","year":"2017","journal-title":"Aging Dis."},{"key":"R20-20250904","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1093\/gerona\/gls097","article-title":"Older people with hip fracture and IADL disability require earlier surgery","volume":"67","author":"Pioli","year":"2012","journal-title":"J Gerontol A Biol Sci Med Sci."},{"key":"R21-20250904","doi-asserted-by":"crossref","first-page":"547","DOI":"10.6061\/clinics\/2012(06)02","article-title":"Early interdisciplinary hospital intervention for elderly patients with hip fractures: functional outcome and mortality","volume":"67","author":"Tarazona-Santabalbina","year":"2012","journal-title":"Clin (Sao Paulo)"},{"key":"R22-20250904","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1016\/j.arth.2023.03.024","article-title":"Effect of fracture type, treatment, and surgeon training on reoperation after Vancouver B periprosthetic femur fractures","volume":"38","author":"Toci","year":"2023","journal-title":"J Arthroplasty"},{"issue":"8","key":"R23-20250904","doi-asserted-by":"crossref","DOI":"10.2106\/JBJS.RVW.21.00008","article-title":"Revision arthroplasty versus open reduction and internal fixation of vancouver type-B2 and B3 periprosthetic femoral fractures","volume":"9","author":"Haider","year":"2021","journal-title":"JBJS Rev"},{"key":"R24-20250904","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.5435\/JAAOS-D-20-00968","article-title":"To fix or revise: differences in periprosthetic distal femur fracture management between trauma and arthroplasty surgeons","volume":"30","author":"Van Rysselberghe","year":"2022","journal-title":"J Am Acad Orthop Surg."}],"container-title":["Journal of Orthopaedic Trauma"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/BOT.0000000000003003","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,4]],"date-time":"2025-09-04T04:00:46Z","timestamp":1756958446000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/BOT.0000000000003003"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":25,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.1097\/bot.0000000000003003","relation":{},"ISSN":["0890-5339","1531-2291"],"issn-type":[{"type":"print","value":"0890-5339"},{"type":"electronic","value":"1531-2291"}],"subject":[],"published":{"date-parts":[[2025,8]]},"assertion":[{"value":"2025-04-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}